ng-nitroarginine methyl ester has been researched along with Chronic Disease in 112 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 39 (34.82) | 18.2507 |
2000's | 58 (51.79) | 29.6817 |
2010's | 14 (12.50) | 24.3611 |
2020's | 1 (0.89) | 2.80 |
Authors | Studies |
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Beaton, HG; Boughton-Smith, N; Cook, TR; Cooper, SL; Fraser-Rae, L; Hallam, K; Hamley, P; McInally, T; Nicholls, DJ; Pimm, AD; Tinker, AC; Wallace, AV | 1 |
Luo, Q; Shen, L; Tang, B; Tu, J; Ye, J; Yu, J; Zhang, M; Zhang, Z | 1 |
Fang, ZH; Gao, JR; Guo, MF; Han, LP; Jiang, NN; Qin, XJ | 1 |
Beber, AP; Bella-Cruz, A; Bresolin, TM; Cechinel-Filho, V; Faloni de Andrade, S; Klein-Júnior, LC; Lemos, M; Rocha, JA; Santin, JR; Silveira, AC; Wagner, TM | 1 |
Gelisgen, R; Genc, H; Guner, I; Hallac, M; Karter, Y; Korkmaz, GG; Sahin, G; Simsek, G; Uzun, DD; Yaman, MO; Yelmen, N | 1 |
de Oliveira Faria, T; Furieri, LB; Lizardo, JH; Padilha, AS; Silveira, EA; Siman, FD; Stefanon, I; Vassallo, DV; Vescovi, MV | 1 |
Gamal-Eldin, MM; Kabil, NN; Seddiek, HA; Yassin, NA | 1 |
Abareghi, F; Nazeri, M; Razavinasab, M; Shabani, M | 1 |
Kruyer, A; Norris, EH; Soplop, N; Strickland, S | 1 |
Baitharu, I; Deep, SN; Gurjar, AK; Prasad, D; Sharma, A; Singh, SB | 1 |
Coutinho, HD; de Albuquerque, TR; de Lacerda Neto, LJ; de Menezes, IR; de Oliveira, LR; de Souza, SD; Dos Santos, AT; Kerntopf, MR; Quintans-Júnior, LJ; Ramos, AG; Santos Sales, V; Wanderley, AG | 1 |
Bulani, VD; Deshpande, PS; Gawali, NB; Gursahani, MS; Juvekar, AR; Kothavade, PS | 1 |
Bonaventura, D; de Oliveira, AM; Tirapelli, CR | 1 |
Baek, WY; Han, CG; Hong, JG; Jeon, Y; Kim, SO; Kwak, KH; Lee, SH; Lim, DG; Park, SS | 1 |
Chadjichristos, C; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Guerrot, D; Helle, F; Jouzel, C; Placier, S | 1 |
Chapman, AC; Cipolla, MJ; Roberts, TJ | 1 |
Garg, R; Gaur, V; Kumar, A; Kumar, P | 1 |
Bauman, WA; Cardozo, CP; DeMeersman, RE; La Fountaine, MF; Radulovic, M; Spungen, AM | 1 |
Fujita, M; Hattori, M; Kishimoto, C; Mikami, Y; Okabe, TA; Shimada, K | 1 |
Gupta, A; Kalonia, H; Kumar, A; Kumar, P; Meena, S | 1 |
Curry, PL; Gao, L; Haack, KK; Pellegrino, PR; Schiller, AM; Zucker, IH | 1 |
Blanco, CE; De Mey, JG; Kessels, LC; Ruijtenbeek, K | 1 |
Andoh, TF; Bennett, WM; Isaac, J; Shihab, FS; Yi, H | 1 |
Arican, N; Elmas, I; Kalayci, R; Kaya, M; Küçük, M | 1 |
Gardner, DS; Giussani, DA | 1 |
Binion, DG; Gutterman, DD; Hatoum, OA; Otterson, MF | 1 |
Bartlett, IS; Marshall, JM | 1 |
Liao, QK; Wang, Q | 1 |
Bishay, M; Coney, AM; Marshall, JM | 1 |
Aschner, JL; Fike, CD; Kaplowitz, MR; Zhang, Y | 1 |
Blom, HJ; De Vriese, AS; Heil, SG; Kluijtmans, LA; Lameire, NH; Mortier, S; Van de Voorde, J | 1 |
Adamidis, A; Mattana, J; Singhal, PC | 1 |
Déciga-Campos, M; Díaz-Reval, MI; González-Trujano, ME; López-Muñoz, FJ; Ventura-Martínez, R | 1 |
Dixon, LJ; Hanratty, CG; Hughes, SM; Johnston, GD; Leahey, WJ; McVeigh, GE; Morgan, DR; Rooney, KP | 1 |
Arata, V; Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Prado, CM; Tibério, IF | 1 |
Boekstegers, P; Brouet, A; Büttner, K; Feron, O; Kupatt, C; Pfosser, A; Thalgott, M | 1 |
Aliev, G; de la Torre, JC | 1 |
Aydin, S; Benian, A; Dariyerli, N; Karter, Y; Kaya, S; Simsek, G; Uzun, H; Yigit, G | 1 |
Capelozzi, VL; Kasahara, DI; Leick-Maldonado, EA; Martins, MA; Prado, CM; Tibério, IF | 1 |
Banasová, A; Bíbová, J; Hampl, V; Herget, J; Hnilicková, O; Lachmanová, V; Miková, D; Uhlík, J | 1 |
Balbinott, AW; Brasileiro-Santos, Mdo S; de Lima, NG; Irigoyen, MC; Passaglia, J; Schaan, BD; Zottis, B | 1 |
Chu, YC; Guan, Y; Johns, RA; Raja, SN; Skinner, J; Tao, YX | 1 |
Bilsborough, W; Burke, V; Erickson, M; Green, DJ; Maiorana, AJ; Minson, CT; O'Driscoll, G; Siong, JH | 1 |
Baylis, C; Erdely, A; Freshour, G | 1 |
Gunning, Y; Hopkins, N; Laffey, JG; McLoughlin, P; O'Croinin, DF | 1 |
Eroglu, L; Ozek, M; Sevgi, S | 1 |
Capelozzi, VL; Leick-Maldonado, EA; Leme, AS; Martins, MA; Prado, CM; Tibério, IF; Yano, L | 1 |
Kulkarni, SK; Padi, SV; Patil, CS; Singh, VP | 1 |
Delles, C; Fleischmann, EH; Klingbeil, AU; Schäufele, TG; Schlaich, MP; Schmieder, RE | 1 |
Alcaraz, A; Atucha, NM; García-Estañ, J; Iyú, D; Ortiz, MC | 1 |
Bahtiyar, MO; Buhimschi, C; Buhimschi, IA; Copel, J; Guller, S; Julien, S; Norwitz, E; Ravishankar, V | 1 |
da Cruz-Höfling, MA; da Silva, GH; Hyslop, S; Paffaro, VA; Pauli, JR; Saad, MJ; Salgado, I; Tarsitano, CA | 1 |
Evans, RG; Fitzgerald, SM; Head, GA; Kemp-Harper, BK; Parkington, HC | 1 |
Grundy, D; McLean, P; Stead, R | 1 |
Kim, JH; Kim, YH; Park, CK; Park, SH | 1 |
Chichester, P; Guven, A; Johnson, A; Juan, YS; Kogan, B; Leggett, R; Levin, RM; Lin, WY; Mannikarottu, A; Neumann, P; Whitbeck, C | 1 |
Allières, C; Banquet, S; Bégueret, H; Bellance, N; Delannoy, E; Desgranges, C; Fresquet, F; Gadeau, A; Leblais, V; Leroux, L; Muller, B | 1 |
Alcaraz, A; Atucha, NM; García-Estañ, J; Hernández, D; Iyú, D; Mota, R; Ortiz, AJ; Ortiz, MC | 1 |
Ahrén, B; Karlsson, S; Scheurink, AJ; Steffens, AB | 1 |
Archer, SL; Hampl, V; Isaacson, TC; Nelson, DP; Weir, EK | 1 |
Flynn, JT; Herndon, DN; Hinder, F; Meyer, J; Stothert, J; Traber, DL; Traber, LD | 1 |
Shudo, H | 1 |
Grisham, MB; Specian, RD; Zimmerman, TE | 1 |
Choi, KC; Kim, W; Lee, J; Park, JW; Yeum, CH; Yoo, K; Yoon, PJ | 1 |
Bouriquet, N; Casellas, D | 1 |
Chotinaruemol, S; Clark, DA; Kakkis, JL; Miller, MJ; Sadowska-Krowicka, H | 1 |
Barer, G; Bee, D; Emery, C; Howard, P; Stewart, A | 1 |
Boegehold, MA | 1 |
Yang, ST | 1 |
Hao, JX; Xu, XJ | 1 |
Adams, HR; Gupta, M; Mattox, ML; Myers, PR; Parker, JL; Rogers, S | 1 |
Chida, M; Voelkel, NF | 1 |
Hashizume, Y; Nasa, Y; Ohaku, H; Sanbe, A; Takeo, S; Toyoshima, H | 1 |
Granger, J; Pigg, K; Schnackenberg, C; Tucker, B | 1 |
Asano, K; Drazen, JM; Haley, KJ; Lilly, CM; Mehta, S; Rollenhagen, JE | 1 |
Dumont, L; Fontaine, E; Jasmin, G; Tanguay, M; Véronneau, M | 1 |
Baggett, HC; Lane, AP; Pillsbury, HC; Prazma, J; Randell, SH; Rose, AS | 1 |
Blaise, G; Dumont, L; Jasmin, G; Tanguay, M | 1 |
Arévalo, M; Atucha, NM; Criado, M; Eleno, N; Flores, O; Garcia-Estañ, J; Hidalgo, F; López-Novoa, JM; Ortíz, MC; Rodríguez-López, AM; Sánchez-Rodríguez, A | 1 |
Dumont, L; Fontaine, E; Jasmin, G; Véronneau, M; Viau, S | 1 |
Nakamura, T | 1 |
Beierwaltes, WH; Sigmon, DH | 1 |
Abbott, BM; Bertelsen, DL; DeSiato, MA; Rumsey, WL | 1 |
Du, J; Li, W; Zhao, B | 1 |
Poston, RS; Reitz, BA; Robbins, RC; Teranishi, K | 1 |
Hashimoto, S; Kawata, T; Koike, T | 1 |
Abe, I; Fujishima, M; Kagiyama, S; Liu, Y; Matsumura, K; Tsuchihashi, T | 1 |
Nekooeian, AA; Pang, CC | 1 |
Criado, M; Esteller, A; López-Novoa, JM; Martín de Arriba, A; Rodríguez-López, AM; Sánchez-Rodríguez, A | 1 |
Morel, N; Noël, F; Silva, CL | 1 |
Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
Buchholz, J; Duckles, SP; Edwards-Teunissen, K | 1 |
Kurnaz, F; Sarioğlu, Y; Utkan, NZ; Utkan, T; Yildirim, S | 1 |
Bogdan, C; Deckert-Schlüter, M; Lorenz, E; Meyer, T; Röllinghoff, M; Schlüter, D | 1 |
Bin, Z; Heping, Z; Jianfeng, J; Junbao, D; Wanzhen, L | 1 |
Adnot, S; Crozatier, B; Depond, S; Eddahibi, S; Laplace, M; Raffestin, B; Rouet-Benzineb, P | 1 |
Bannigan, JG; Cadogan, E; Giles, S; Hopkins, N; McLoughlin, P; Moynihan, J | 1 |
Ferguson, DJ; McLeod, R; Roberts, CW; Roberts, F | 1 |
Badavi, M; Hajizadeh, S; Khoshbaten, A | 1 |
Andoh, TF; Bennett, WM; Shihab, FS; Yi, H | 1 |
Egashira, K; Kitamoto, S; Koyanagi, M; Ni, W; Shimokawa, H; Takeshita, A; Takeya, M; Yoshimura, T | 1 |
Bernheim, J; Bursztyn, M; Mekler, J; Peleg, E | 1 |
Blumberg, FC; Lorenz, C; Pfeifer, M; Riegger, GA; Sandner, P; Wolf, K | 1 |
Egashira, K; Kataoka, C; Katoh, M; Kitamoto, S; Koyanagi, M; Narita, H; Ohmachi, Y; Takeshita, A; Usui, M | 1 |
Bader, M; Fletcher, EC; Joshua, IG; Orolinova, N; Tahawi, Z | 1 |
Chrissobolis, S; Sobey, CG | 1 |
Jover, B; Mimran, A | 1 |
Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Okubo, K; Ozawa, Y; Saruta, T; Tokuyama, H | 1 |
Anderson, CR; Chrissobolis, S; Chu, Y; Faraci, FM; Sobey, CG; Ziogas, J | 1 |
Fung, ML; Fung, PC; Tipoe, GL; Ye, JS | 1 |
Ago, T; Fujishima, M; Ibayashi, S; Kamouchi, M; Kitazono, T; Ooboshi, H; Santa, N | 1 |
Demir, N; Ergüler, G; Erkiliç, M; Kuru, O; Sentürk, UK; Yeşilkaya, A | 1 |
2 review(s) available for ng-nitroarginine methyl ester and Chronic Disease
Article | Year |
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Nitric oxide and tubulointerstitial nephritides.
Topics: Animals; Biomarkers; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Transgenic; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prognosis; Severity of Illness Index | 2004 |
Nitric oxide inhibition and renal alterations.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Humans; Kidney; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
1 trial(s) available for ng-nitroarginine methyl ester and Chronic Disease
Article | Year |
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Effects of acute nitric oxide synthase inhibition on lower leg vascular function in chronic tetraplegia.
Topics: Adult; Analysis of Variance; Blood Pressure; Blood Volume; Case-Control Studies; Chronic Disease; Enzyme Inhibitors; Female; Humans; Leg; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plethysmography; Quadriplegia; Vascular Resistance | 2009 |
109 other study(ies) available for ng-nitroarginine methyl ester and Chronic Disease
Article | Year |
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1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.
Topics: Acute Disease; Administration, Oral; Amines; Animals; Arthritis, Experimental; Cell Line; Chronic Disease; Enzyme Inhibitors; Injections, Intravenous; Isoenzymes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quinazolines; Rats; Spiro Compounds; Structure-Activity Relationship | 2003 |
Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps.
Topics: Chronic Disease; Humans; Interleukin-13; Nasal Mucosa; Nasal Polyps; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proto-Oncogene Proteins c-akt; Retrospective Studies; Rhinitis; Sinusitis | 2023 |
To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway.
Topics: Animals; Aorta, Abdominal; Blood Glucose; Blood Pressure; Chronic Disease; Diabetes Mellitus, Type 2; Glycosylation; Heart Rate; Human Umbilical Vein Endothelial Cells; Humans; Male; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Phosphatidylinositol 3-Kinases; Phosphorylation; Prognosis; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Treatment Outcome | 2019 |
Role of gastric mucus secretion, oxinitrergic system and sulfhydryl groups on the gastroprotection elicited by Polygala cyparissias (Polygalaceae) in mice.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Ethanol; Gastric Mucosa; Helicobacter pylori; Hydrochloric Acid; Kaempferols; Mice; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phytotherapy; Plant Extracts; Polygala; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Xanthones | 2013 |
The effect of chronic long-term intermittent hypobaric hypoxia on bone mineral density in rats: role of nitric oxide.
Topics: Alkaline Phosphatase; Animals; Bone Density; Chronic Disease; Cytokines; Enzyme Inhibitors; Humans; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parathyroid Hormone; Rats; Rats, Wistar; Time Factors | 2013 |
Low-dose chronic lead exposure increases systolic arterial pressure and vascular reactivity of rat aortas.
Topics: Acetophenones; Animals; Antioxidants; Aorta; Blood Pressure; Chronic Disease; Cyclooxygenase 2 Inhibitors; Indomethacin; Lead Poisoning; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Renin-Angiotensin System; Superoxide Dismutase; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2014 |
Effect of ghrelin on chronic liver injury and fibrogenesis in male rats: possible role of nitric oxide.
Topics: Animals; bcl-2-Associated X Protein; Chronic Disease; Enzyme Inhibitors; Gene Expression Regulation; Ghrelin; Liver; Liver Cirrhosis; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats | 2014 |
Role of nitric oxide in altered nociception and memory following chronic stress.
Topics: Animals; Anxiety; Arginine; Avoidance Learning; Chronic Disease; Electroshock; Enzyme Inhibitors; Exploratory Behavior; Hot Temperature; Hyperalgesia; Learning Disabilities; Male; Memory; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociception; Rats, Sprague-Dawley; Stress, Psychological; Swimming | 2014 |
Chronic Hypertension Leads to Neurodegeneration in the TgSwDI Mouse Model of Alzheimer's Disease.
Topics: Age of Onset; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Blood-Brain Barrier; Brain; Cerebral Amyloid Angiopathy; Chronic Disease; Dementia, Vascular; Disease Models, Animal; Female; Hippocampus; Humans; Hypertension; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Mutation; Nerve Degeneration; NG-Nitroarginine Methyl Ester; Pericytes; Vasculitis | 2015 |
Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour.
Topics: Air Pressure; Animals; Behavior, Animal; Chronic Disease; Crowding; Cytoprotection; Depression; Hypoxia; Male; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2016 |
Gastroprotective and ulcer healing effects of hydroethanolic extract of leaves of Caryocar coriaceum: Mechanisms involved in the gastroprotective activity.
Topics: Animals; Antioxidants; Capsaicin; Chromatography, High Pressure Liquid; Chronic Disease; Disease Models, Animal; Ericales; Ethanol; Female; Flavonoids; Gastrointestinal Motility; Glyburide; Histamine; Indomethacin; Male; Mice; Mucus; Naloxone; NG-Nitroarginine Methyl Ester; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Protective Agents; Stomach Ulcer; Water; Yohimbine | 2017 |
Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway.
Topics: Agmatine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Chronic Disease; Cognition Disorders; Cognitive Dysfunction; Corticosterone; Depression; Depressive Disorder; Hippocampus; Male; Maze Learning; Mice; NG-Nitroarginine Methyl Ester; Signal Transduction; Stress, Psychological | 2017 |
Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid.
Topics: Animals; Bradykinin; Cardiovascular Agents; Carotid Arteries; Chronic Disease; Enzyme Inhibitors; Hyperhomocysteinemia; Indazoles; Indomethacin; Male; Methionine; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin Antagonists; Rats; Rats, Wistar; Receptors, Thromboxane A2, Prostaglandin H2; Vasodilator Agents; Xanthones | 2009 |
Reactive oxygen species in rats with chronic post-ischemia pain.
Topics: Allopurinol; Animals; Chronic Disease; Cold Temperature; Enzyme Inhibitors; Free Radical Scavengers; Ischemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Xanthine Oxidase | 2009 |
Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism.
Topics: Animals; Arterioles; Blood Pressure; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Hypertension; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Quinazolines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstriction | 2009 |
PPAR-gamma agonist rosiglitazone reverses increased cerebral venous hydraulic conductivity during hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Brain Edema; Capillary Permeability; Cerebral Veins; Cerebrovascular Circulation; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Female; Hydrostatic Pressure; Hypertension; NG-Nitroarginine Methyl Ester; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Spin Labels; Thiazolidinediones; Time Factors | 2009 |
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous System Stimulants; Chronic Disease; Cyclohexanols; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Random Allocation; Swimming; Venlafaxine Hydrochloride | 2010 |
Therapy with granulocyte colony-stimulating factor in the chronic stage, but not in the acute stage, improves experimental autoimmune myocarditis in rats via nitric oxide.
Topics: Acute Disease; Animals; Autoimmune Diseases; Cardiac Myosins; Chronic Disease; Cytokines; Echocardiography; Enzyme Inhibitors; Granulocyte Colony-Stimulating Factor; Humans; Immunization; Immunoenzyme Techniques; Myocarditis; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred Lew; Recombinant Proteins; Superoxides; Swine | 2010 |
Effect of nitric oxide in protective effect of melatonin against chronic constriction sciatic nerve injury induced neuropathic pain in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Chronic Disease; Disease Models, Animal; Glutathione; Hyperalgesia; Lipid Peroxidation; Male; Melatonin; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve | 2011 |
Central Rho kinase inhibition restores baroreflex sensitivity and angiotensin II type 1 receptor protein imbalance in conscious rabbits with chronic heart failure.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Baroreflex; Brain Stem; Chronic Disease; Consciousness; Enzyme Inhibitors; Heart; Heart Failure; Heart Rate; Male; Metoprolol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rabbits; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Sympathetic Nervous System; Vagus Nerve | 2013 |
Chronic moderate hypoxia and protein malnutrition both induce growth retardation, but have distinct effects on arterial endothelium-dependent reactivity in the chicken embryo.
Topics: Acetylcholine; Animals; Chick Embryo; Chickens; Chronic Disease; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Fetal Growth Retardation; Fetal Hypoxia; NG-Nitroarginine Methyl Ester; Nitroprusside; Protein-Energy Malnutrition; Vasodilation; Vasodilator Agents | 2003 |
Nitric oxide modulates vascular endothelial growth factor and receptors in chronic cyclosporine nephrotoxicity.
Topics: Animals; Chronic Disease; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2003 |
Effect of aluminum on the blood-brain barrier permeability during nitric oxide-blockade-induced chronic hypertension in rats.
Topics: Aluminum; Animals; Blood Pressure; Blood-Brain Barrier; Body Weight; Chronic Disease; Coloring Agents; Enzyme Inhibitors; Evans Blue; Hypertension; Indicators and Reagents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2003 |
Enhanced umbilical blood flow during acute hypoxemia after chronic umbilical cord compression: a role for nitric oxide.
Topics: Acute Disease; Animals; Blood Flow Velocity; Blood Gas Analysis; Chronic Disease; Constriction, Pathologic; Disease Models, Animal; Enzyme Inhibitors; Fetal Diseases; Fetus; Hemodynamics; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Regional Blood Flow; Sheep; Umbilical Cord | 2003 |
Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation.
Topics: Acetylcholine; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Endothelium, Vascular; Enzyme Inhibitors; Humans; In Vitro Techniques; Intestines; Ischemia; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2003 |
Effects of chronic systemic hypoxia on contraction evoked by noradrenaline in the rat iliac artery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Carbon Dioxide; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypoxia; Iliac Artery; Isoproterenol; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Oxygen; Phenylephrine; Potassium; Rats; Receptors, Adrenergic, alpha; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Yohimbine | 2003 |
[Effect of nitric oxide on iron metabolism in rats with anemia of chronic disease].
Topics: Aconitate Hydratase; Anemia; Animals; Chronic Disease; Hemoglobins; Iron; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2003 |
Influence of endogenous nitric oxide on sympathetic vasoconstriction in normoxia, acute and chronic systemic hypoxia in the rat.
Topics: Acute Disease; Animals; Chronic Disease; Electric Stimulation; Enzyme Inhibitors; Guanidines; Hindlimb; Hypoxia; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Wistar; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 2004 |
Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets.
Topics: Animals; Animals, Newborn; Caveolin 1; Caveolins; Chronic Disease; Enzyme Inhibitors; Guanidines; HSP90 Heat-Shock Proteins; Hypoxia; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Signal Transduction; Swine | 2004 |
Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia.
Topics: Acetylcholine; Acute Disease; Adenosine; Animals; Biological Factors; Chronic Disease; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Hyperhomocysteinemia; Indomethacin; Methionine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Renal Circulation; Vasodilation; Vitamin B Complex; Vitamin B Deficiency | 2004 |
Peripheral involvement of the nitric oxide-cGMP pathway in the indomethacin-induced antinociception in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Gout; Indomethacin; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Signal Transduction; Uric Acid | 2004 |
Impaired endothelium-dependent and -independent vasodilation in elderly patients with chronic heart failure.
Topics: Acetylcholine; Aged; Aged, 80 and over; Area Under Curve; Case-Control Studies; Chronic Disease; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Heart Failure; Humans; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Plethysmography; Regional Blood Flow; Stroke Volume; United Kingdom; Vasodilation; Vasodilator Agents | 2004 |
Neurokinins and inflammatory cell iNOS expression in guinea pigs with chronic allergic airway inflammation.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Bronchial Hyperreactivity; Capsaicin; Chronic Disease; Elasticity; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Inflammation; Lung; Male; Neurokinin A; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin | 2005 |
Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia.
Topics: Animals; Capillaries; Chronic Disease; DNA, Complementary; Female; Genetic Therapy; HSP90 Heat-Shock Proteins; Ischemia; Liposomes; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Transfection | 2005 |
Inhibition of vascular nitric oxide after rat chronic brain hypoperfusion: spatial memory and immunocytochemical changes.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Chronic Disease; Cognition Disorders; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Male; Maze Learning; Memory; Microscopy, Electron; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Space Perception | 2005 |
The role of nitric oxide on bone metabolism in ovariectomized rats following chronic ethanol intake.
Topics: Alcohol Drinking; Animals; Bone Resorption; Chronic Disease; Cytokines; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Rats; Rats, Wistar | 2005 |
Effects of acute and chronic nitric oxide inhibition in an experimental model of chronic pulmonary allergic inflammation in guinea pigs.
Topics: Animals; Asthma; Chronic Disease; Collagen; Disease Models, Animal; Enzyme Inhibitors; Guinea Pigs; Leukocytes, Mononuclear; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovalbumin; Pneumonia; Pulmonary Edema | 2005 |
Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension.
Topics: Administration, Oral; Animals; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exhalation; Hypertension, Pulmonary; Hypoxia; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Tyrosine | 2006 |
Dose-dependent autonomic dysfunction in chronic L-NAME-hypertensive diabetic rats.
Topics: Animals; Autonomic Nervous System Diseases; Baroreflex; Blood Pressure; Chronic Disease; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 2005 |
Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain.
Topics: Animals; Behavior, Animal; Chronic Disease; Freund's Adjuvant; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pain Threshold; Posterior Horn Cells | 2005 |
Impaired skin blood flow response to environmental heating in chronic heart failure.
Topics: Blood Flow Velocity; Blood Pressure; Body Temperature; Body Temperature Regulation; Chronic Disease; Enzyme Inhibitors; Heart Failure; Heating; Hot Temperature; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Skin; Vasodilation | 2006 |
Resistance to renal damage by chronic nitric oxide synthase inhibition in the Wistar-Furth rat.
Topics: Animals; Chronic Disease; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen Dioxide; omega-N-Methylarginine; Puromycin; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Time Factors | 2006 |
Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection.
Topics: Animals; Arginine; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Interleukin-1; Interleukin-6; Lung; Lung Diseases; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pseudomonas Infections; Rats; Rats, Inbred WKY; Tyrosine; Vascular Endothelial Growth Factor A | 2006 |
L-NAME prevents anxiety-like and depression-like behavior in rats exposed to restraint stress.
Topics: Acute Disease; Animals; Anxiety; Arginine; Chronic Disease; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2006 |
Effects of nitric oxide synthases in chronic allergic airway inflammation and remodeling.
Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Chronic Disease; Enzyme Inhibitors; Eosinophils; Guinea Pigs; Inhalation; Isoenzymes; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovalbumin; Pneumonia; Respiratory Mechanics; Time Factors; Trachea | 2006 |
Sildenafil induces hyperalgesia via activation of the NO-cGMP pathway in the rat neuropathic pain model.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chronic Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Threshold; Piperazines; Purines; Rats; Rats, Wistar; Sciatic Neuropathy; Signal Transduction; Sildenafil Citrate; Sulfones | 2006 |
Impaired basal NO activity in patients with glomerular disease and the influence of oxidative stress.
Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; Case-Control Studies; Chronic Disease; Drug Combinations; Endothelium, Vascular; Enzyme Inhibitors; Fasting; Female; Glomerular Filtration Rate; Glomerulonephritis; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Reference Values; Regional Blood Flow; Vasodilation | 2006 |
Vitamin E supplementation reverses renal altered vascular reactivity in chronic bile duct-ligated rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Bile Ducts; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Kidney; Ligation; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Nitroprusside; Perfusion; Phenylephrine; Random Allocation; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents; Vasodilator Agents; Vitamin E | 2007 |
Contrasting effects of chronic hypoxia and nitric oxide synthase inhibition on circulating angiogenic factors in a rat model of growth restriction.
Topics: Animals; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Female; Fetal Growth Retardation; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2007 |
Hepatic morphological alterations, glycogen content and cytochrome P450 activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME).
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Chronic Disease; Cytochrome P-450 Enzyme System; Enalapril; Enzyme Activation; Enzyme Inhibitors; Fasting; Glucose; Glycogen; Glycogen Synthase Kinase 3; Hypertension; Hypertrophy; Liver; Liver Cirrhosis; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Endothelial dysfunction and arterial pressure regulation during early diabetes in mice: roles for nitric oxide and endothelium-derived hyperpolarizing factor.
Topics: Acetylcholine; Animals; Biological Factors; Blood Pressure; Chronic Disease; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelium, Vascular; Enzyme Inhibitors; Heart Rate; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandins; Vasodilation; Vasodilator Agents | 2007 |
Impact of 5-HT3 receptor blockade on colonic haemodynamic responses to ischaemia and reperfusion in the rat.
Topics: Acute Disease; Animals; Carbolines; Chronic Disease; Colitis; Colon; Enzyme Inhibitors; Hyperemia; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Regional Blood Flow; Reperfusion Injury; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Ultrasonography, Doppler | 2007 |
Expression of neuronal nitric oxide synthase in the retina of a rat model of chronic glaucoma.
Topics: Animals; Blotting, Western; Cell Count; Chronic Disease; Glaucoma; Immunohistochemistry; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Retinal Horizontal Cells | 2007 |
Effects of L-arginine and L-NAME on chronic partial bladder outlet obstruction in rabbit.
Topics: Animals; Arginine; Chronic Disease; Dose-Response Relationship, Drug; Drug Interactions; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rabbits; Treatment Outcome; Urinary Bladder; Urinary Bladder Neck Obstruction | 2007 |
beta-adrenergic relaxation in pulmonary arteries: preservation of the endothelial nitric oxide-dependent beta2 component in pulmonary hypertension.
Topics: Animals; Chronic Disease; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Reactive Oxygen Species; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-2; Vasodilation | 2008 |
Effects of chronic L-NAME on nitrotyrosine expression and renal vascular reactivity in rats with chronic bile-duct ligation.
Topics: Animals; Body Weight; Chronic Disease; Kidney; Liver Cirrhosis, Experimental; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Circulation; Spleen; Tyrosine | 2008 |
Involvement of nitric oxide in neuroglycopenia-induced insulin and glucagon secretion in the mouse.
Topics: Animals; Arginine; Blood Glucose; Carbachol; Catecholamines; Chronic Disease; Deoxyglucose; Drug Interactions; Female; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Stimulation, Chemical | 1995 |
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
Topics: Animals; Arginine; Chronic Disease; Hypertension; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasoconstriction | 1994 |
Increased organ blood flow in chronic endotoxemia is reversed by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Chronic Disease; Escherichia coli; Female; Lactates; Lactic Acid; Lipopolysaccharides; Microspheres; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Regional Blood Flow; Sheep; Thromboxane B2; Toxemia; Vascular Resistance; Vasodilation | 1994 |
[Study on roles of L-arginine to nitric oxide pathway for the cardiovascular control: assessment with a new model of hypertension produced by the chronic administration of nitric oxide synthase inhibitor].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Chronic Disease; Disease Models, Animal; Hemodynamics; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System | 1994 |
Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Chronic Disease; Crohn Disease; Female; Guanidines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Inbred Lew | 1994 |
Impairment of endothelium-dependent vasorelaxation in chronic two-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Chronic Disease; Disease Models, Animal; Hypertension, Renal; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation | 1995 |
Chronic L-NAME hypertension in rats and autoregulation of juxtamedullary preglomerular vessels.
Topics: Actins; Animals; Arginine; Blood Pressure; Blood Vessels; Chronic Disease; Hemodynamics; Homeostasis; Hypertension; Juxtaglomerular Apparatus; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation | 1995 |
Amelioration of chronic ileitis by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chronic Disease; Disease Models, Animal; Guinea Pigs; Ileitis; Ileum; Intestinal Mucosa; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Peroxidase; Therapeutic Irrigation; Trinitrobenzenesulfonic Acid | 1993 |
Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats.
Topics: Almitrine; Animals; Arginine; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Endothelins; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Rats; Rats, Wistar; Respiration; Vasoconstriction | 1993 |
Enhanced arteriolar vasomotion in rats with chronic salt-induced hypertension.
Topics: Animals; Arginine; Arterioles; Chronic Disease; Hypertension; Male; Muscles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred Strains; Sodium, Dietary; Vasomotor System | 1993 |
Role of nitric oxide in the maintenance of resting cerebral blood flow during chronic hypertension.
Topics: Animals; Arginine; Blood Pressure; Cerebrovascular Circulation; Chronic Disease; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sensitivity and Specificity | 1996 |
Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered nitric oxide synthase inhibitors.
Topics: Adrenergic Agonists; Analgesics; Animals; Arousal; Blood Pressure; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Female; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain; Physical Stimulation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 1996 |
Chronic endotoxemia and endothelium-dependent vasodilation in coronary arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Body Temperature; Body Weight; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Endotoxemia; Hemodynamics; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; omega-N-Methylarginine; Rabbits; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Effects of acute and chronic hypoxia on rat lung cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Disease; Animals; Blotting, Northern; Chronic Disease; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Hypoxia; Isoenzymes; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
Topics: Animals; Aorta, Thoracic; Cardiac Output, Low; Chronic Disease; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Heart; Isoproterenol; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Norepinephrine; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation | 1996 |
Role of nitric oxide in modulating the chronic renal and arterial pressure responses to angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chronic Disease; Dogs; Enzyme Inhibitors; Glomerular Filtration Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Renal Plasma Flow; Vasoconstrictor Agents | 1997 |
Acute and chronic effects of allergic airway inflammation on pulmonary nitric oxide production.
Topics: Acute Disease; Administration, Inhalation; Animals; Antigens; Bronchitis; Cholinergic Antagonists; Chronic Disease; Enzyme Inhibitors; Guinea Pigs; Hypersensitivity; Male; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pneumonia; Pulmonary Alveoli; Trachea; Vagotomy | 1997 |
Reactivity to endothelium-dependent and -independent vasoactive substances is maintained in coronary resistance vessels of the failing hamster heart.
Topics: Acetylcholine; Animals; Cardiomyopathy, Dilated; Chronic Disease; Coronary Vessels; Cricetinae; Cyclooxygenase Inhibitors; Endothelium, Vascular; Indomethacin; Mesocricetus; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Perfusion; Potassium Channels; Tetraethylammonium Compounds; Vasodilator Agents | 1997 |
Nitric oxide mediates mucin secretion in endotoxin-induced otitis media with effusion.
Topics: Animals; Chronic Disease; Ear, Middle; Enzyme-Linked Immunosorbent Assay; Epithelium; Immunohistochemistry; Lipopolysaccharides; Mucins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Otitis Media with Effusion; Rats; Rats, Sprague-Dawley; Therapeutic Irrigation | 1997 |
Coronary and cardiac sensitivity to the vasoselective benzothiazepine-like calcium antagonist, clentiazem, in experimental heart failure.
Topics: Animals; Body Weight; Calcium Channel Blockers; Chronic Disease; Coronary Vessels; Cricetinae; Cyclooxygenase Inhibitors; Diltiazem; Enzyme Inhibitors; Heart; Heart Failure; In Vitro Techniques; Indomethacin; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase | 1997 |
Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: role of inducible nitric oxide synthase activation.
Topics: Animals; Chronic Disease; Enzyme Activation; Guanidines; Kidney Glomerulus; Liver Cirrhosis, Experimental; Lymphocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Myocardial reactive hyperemia in experimental chronic heart failure: evidence for the role of K+ adenosine triphosphate-dependent channels and cyclooxygenase activity.
Topics: Animals; Cardiac Output, Low; Chronic Disease; Coronary Circulation; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Hyperemia; Indomethacin; NG-Nitroarginine Methyl Ester; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Theophylline | 1997 |
[Contribution of L-arginine-derived nitric oxide to the structural integrity of coronary artery and cardiac interstitium, and to the regulation of sympathetic nerve activity: assessment using a rat model produced by chronic nitric oxide inhibition].
Topics: Animals; Arginine; Catecholamines; Chronic Disease; Coronary Vessels; Disease Models, Animal; Fibrosis; Heart Rate; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renin; Sympathetic Nervous System | 1997 |
Influence of nitric oxide in the chronic phase of two-kidney, one clip renovascular hypertension.
Topics: Animals; Antihypertensive Agents; Chronic Disease; Enzyme Inhibitors; Hemodynamics; Hypertension, Renovascular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Renal Circulation | 1998 |
Nitric oxide and endothelin in acute hypoxic pulmonary vasoconstriction and adaptation to chronic hypoxia.
Topics: Acclimatization; Acute Disease; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Chronic Disease; Endothelium, Vascular; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction | 1997 |
[Impact of nitric oxide on endothelin gene expression in intrapulmonary arteries of chronic hypoxic rats].
Topics: Animals; Chronic Disease; Endothelin-1; Gene Expression; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger | 1997 |
Effect of low molecular weight heparin on suppression of chronic graft vascular disease in a rat cardiac allograft model.
Topics: Anastomosis, Surgical; Animals; Aorta, Abdominal; Chronic Disease; Coronary Artery Disease; Coronary Vessels; Cyclosporine; Fibrinolytic Agents; Heart Transplantation; Heparin, Low-Molecular-Weight; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Postoperative Complications; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Transplantation, Heterotopic; Transplantation, Homologous; Vena Cava, Inferior | 1998 |
Effects of chronic nitric oxide synthase inhibition on renal function and histology in polycythemic rats.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chronic Disease; Enzyme Inhibitors; Erythropoietin; Follow-Up Studies; Glomerular Filtration Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polycythemia; Prodrugs; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tetrazoles | 1998 |
Central and peripheral mechanisms involved in hypertension induced by chronic inhibition of nitric oxide synthase in rats.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Denervation; Enzyme Inhibitors; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phentolamine; Rats; Rats, Wistar; Sinoatrial Node; Tetrazoles | 1998 |
Estrogen restores role of basal nitric oxide in control of vascular tone in rats with chronic heart failure.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output, Low; Chronic Disease; Coronary Vessels; Delayed-Action Preparations; Drug Implants; Enzyme Inhibitors; Estradiol; Female; Ligation; NG-Nitroarginine Methyl Ester; Nitroprusside; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus; Vascular Resistance; Vasodilator Agents | 1998 |
Increased nitric oxide synthesis and inducible nitric oxide synthase expression in patients with alcoholic and non-alcoholic liver cirrhosis.
Topics: Blotting, Northern; Cardiac Output; Chronic Disease; Endotoxins; Enzyme Activation; Female; Humans; Leukocytes, Mononuclear; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; Vascular Resistance | 1998 |
Portal veins of mice infected with Schistosoma mansoni exhibit an increased reactivity to 5-hydroxytryptamine.
Topics: Animals; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Schistosomiasis mansoni; Serotonin | 1998 |
Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Diltiazem; Disease Models, Animal; Endothelium, Vascular; Hypertension; Isoquinolines; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Treatment Outcome; Vasodilation; Vasodilator Agents | 1999 |
Impact of development and chronic hypoxia on NE release from adrenergic nerves in sheep arteries.
Topics: Adrenergic Fibers; Aging; Animals; Arteries; Capsaicin; Chronic Disease; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Fetus; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Sheep | 1999 |
Effects of chronic unilateral internal pudendal arterial occlusion on reactivity of isolated corpus cavernosum strips from rabbits.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Arteries; Carbachol; Chronic Disease; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Parasympathomimetics; Penis; Phenylephrine; Potassium Chloride; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Inhibition of inducible nitric oxide synthase exacerbates chronic cerebral toxoplasmosis in Toxoplasma gondii-susceptible C57BL/6 mice but does not reactivate the latent disease in T. gondii-resistant BALB/c mice.
Topics: Administration, Oral; Animals; Brain; Chronic Disease; Encephalitis; Enzyme Induction; Enzyme Inhibitors; Female; Genetic Predisposition to Disease; Immunity, Innate; Kinetics; Lysine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Species Specificity; Toxoplasma; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral | 1999 |
Nitric oxide impacts endothelin-1 gene expression in intrapulmonary arteries of chronically hypoxic rats.
Topics: Animals; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Hypoxia; In Situ Hybridization; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Vasodilator Agents | 1999 |
Induction of cardiac nitric oxide synthase 2 in rats exposed to chronic hypoxia.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Chronic Disease; Enzyme Induction; Heart Ventricles; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Interleukin-6; Male; Molecular Sequence Data; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments; Protein Kinase C; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Function, Right | 1999 |
Enhanced expression of inducible nitric oxide synthase without vasodilator effect in chronically infected lungs.
Topics: Animals; Chronic Disease; Enzyme Inhibitors; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Perfusion; Pressure; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Vasodilation | 1999 |
Inhibition of nitric oxide production exacerbates chronic ocular toxoplasmosis.
Topics: Animals; Chronic Disease; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Toxoplasmosis, Animal; Toxoplasmosis, Ocular | 2000 |
Decreased response of rat knee joint blood vessels to phenylephrine in chronic inflammation: involvement of nitric oxide.
Topics: Adrenergic alpha-Antagonists; Animals; Arthritis, Experimental; Blood Pressure; Chronic Disease; Enzyme Inhibitors; Forelimb; Joints; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Regional Blood Flow; Synovial Membrane; Time Factors; Vasoconstrictor Agents | 2000 |
Effect of nitric oxide modulation on TGF-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity.
Topics: Animals; Arginine; Arterioles; Biglycan; Blood Pressure; Blotting, Northern; Chronic Disease; Collagen; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hyalin; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Proteoglycans; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 2000 |
Role of monocyte chemoattractant protein-1 in cardiovascular remodeling induced by chronic blockade of nitric oxide synthesis.
Topics: Animals; Antibodies, Monoclonal; Blood Pressure; Cell Division; Chemokine CCL2; Chronic Disease; Collagen; Coronary Artery Disease; Dermis; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Inflammation; Male; Monocytes; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Recombinant Proteins; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling | 2000 |
Subpressor dose of L-NAME unmasks hypertensive effect of chronic hyperinsulinemia.
Topics: Animals; Blood Pressure; Chronic Disease; Dose-Response Relationship, Drug; Drug Implants; Enzyme Inhibitors; Hyperinsulinism; Hypertension; Insulin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vasodilation | 2000 |
The NO donor molsidomine reduces endothelin-1 gene expression in chronic hypoxic rat lungs.
Topics: Animals; Chronic Disease; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger; Vasodilator Agents | 2001 |
Regression by ACE inhibition of arteriosclerotic changes induced by chronic blockade of NO synthesis in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Apoptosis; Blood Pressure; Chronic Disease; Coronary Artery Disease; Coronary Vessels; Enzyme Inhibitors; Imidazoles; Imidazolidines; In Situ Nick-End Labeling; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred WKY | 2001 |
Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Chronic Disease; Circadian Rhythm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation, Enzymologic; Hypoxia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes; Telemetry; Transcription, Genetic; Vasodilation | 2001 |
Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C.
Topics: Amides; Animals; Basilar Artery; Blood Pressure; Cerebral Arteries; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; Species Specificity; Vasodilator Agents; Vasomotor System | 2001 |
Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Chronic Disease; Dinoprostone; Dipyrone; Dogs; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Ischemia; Kidney; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Prostaglandins; Renal Artery; Renal Artery Obstruction | 2002 |
Neuronal NO mediates cerebral vasodilator responses to K+ in hypertensive rats.
Topics: Animals; Barium; Basilar Artery; Cerebral Arteries; Chronic Disease; Enzyme Inhibitors; Hypertension; Imidazoles; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Vasodilation | 2002 |
Augmentation of hypoxia-induced nitric oxide generation in the rat carotid body adapted to chronic hypoxia: an involvement of constitutive and inducible nitric oxide synthases.
Topics: Animals; Carotid Body; Chronic Disease; Electrodes; Electrophysiology; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2002 |
Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo.
Topics: Acetylcholine; Amides; Animals; Antihypertensive Agents; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; NG-Nitroarginine Methyl Ester; Nicardipine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2002 |
Effect of exercise on blood pressure in rats with chronic NOS inhibition.
Topics: Adaptation, Physiological; Animals; Aorta; Blood Pressure; Body Weight; Chronic Disease; Heart; Heart Rate; Hypertension; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Physical Conditioning, Animal; Rats; Rats, Wistar | 2002 |