ng-nitroarginine methyl ester has been researched along with Cardiovascular Stroke in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (13.11) | 18.2507 |
| 2000's | 65 (53.28) | 29.6817 |
| 2010's | 37 (30.33) | 24.3611 |
| 2020's | 4 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Böhm, F; Collado, A; Jiao, T; Jurga, J; Mahdi, A; Pernow, J; Saleh, N; Tengbom, J; Verouhis, D; Yang, J; Zhou, Z | 1 |
| Derkachev, IA; Maslov, LN; Naryzhnaya, NV; Sementsov, AS | 1 |
| Bao, H; Cheng, X; Deng, H; Hu, X; Huang, X; Wan, K; Wang, D; Wang, H; Wu, Q; Xu, Z; Zhan, B; Zhang, Y | 1 |
| Boricic, N; Bozic Nedeljkovic, B; Celic, V; Djuric, D; Ilic, A; Mutavdzin, S; Simic, T; Stankovic, S; Stevanovic, P; Todorovic, D | 1 |
| Duan, MX; Liao, HH; Liu, C; Meng, YY; Tang, QZ; Wu, QQ; Xiao, Y; Yang, Z; Yuan, Y | 1 |
| Maslov, LN; Naryzhnaya, NV | 1 |
| Basiri, S; Enayati, A; Ghorghanlu, S; Khori, V; Mazaheri, Z; Pourabouk, M; Rajaei, M; Yassa, N | 1 |
| Feng, L; Kang, L; Li, J; Li, Y; Liu, J; Ma, C; Qi, Z; Ren, J; Yang, G; Yang, L; Zhang, S | 1 |
| Ding, Z; Jiang, S; Li, C; Li, J; Liu, L; Liu, Y; Xie, J; Zhang, X; Zhang, Y; Zhu, W | 1 |
| Angelos, MG; Aune, SE; Khan, M; Kuppusamy, ML; Kuppusamy, P; Yeh, ST | 1 |
| Bi, X; He, X; Liu, J; Lu, Y; Qin, F; Yu, X; Zang, W; Zhao, M | 1 |
| Ahn, Y; Bae, JW; Cho, AS; Cho, HH; Cho, MC; Hong, MH; Hwang, KK; Jeong, HY; Jeong, MH; Kang, WS; Kim, JS; Kim, YS; Kwon, JS | 1 |
| Ding, L; Gao, G; Hu, L; Hu, T; Jin, Z; Li, H; Lu, B; Lu, X; Yu, X; Zhang, L; Zhang, Z | 1 |
| Faghihi, M; Houshmand, F; Zahediasl, S | 1 |
| Fernandes, AA; Padilha, AS; Silveira, EA; Siman, FD; Stefanon, I; Vassallo, DV | 1 |
| Jia, D; Li, W; Lv, Y; Shu, W; Wu, N | 2 |
| Britto, LR; Couto, GK; Mill, JG; Rossoni, LV | 1 |
| Buelna-Chontal, M; Chagoya, V; Correa, F; García-Niño, WR; García-Rivas, G; Hernández-Pando, R; León-Contreras, JC; Pedraza-Chaverri, J; Vigueras, RM; Zazueta, C | 1 |
| Cao, J; Qiao, S; Shao, Q; Sun, Y; Wang, C; Wu, H; Xie, H; Ying, M; Zhu, J | 1 |
| Ding, M; Fu, E; Fu, F; Han, H; Lei, J; Li, W; Qu, Y; Wang, X | 1 |
| Lishmanov, YB; Maslov, LN; Naryzhnaya, NV; Prokudina, ES; Tsibulnikov, SY | 1 |
| Del Mauro, J; Donato, M; Evelson, P; Garces, M; Gelpi, RJ; Goyeneche, MA; Höcht, C; Marchini, T; Pérez, V; Rodríguez, M | 1 |
| Hao, L; Lin, MJ; Rong, B; Sun, T; Xie, F; Zhong, JQ | 1 |
| Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K | 1 |
| Bazargan, M; Dehpour, AR; Faghihi, M; Mirershadi, F | 1 |
| Akin, KO; Aypar, E; Basgut, B; Basgut, E; Cakici, I; Kilic, N | 1 |
| Aoyama, T; Bao, N; Iwasa, M; Kawamura, I; Kawasaki, M; Kobayashi, H; Minatoguchi, S; Nagashima, K; Nishigaki, K; Sumi, S; Takemura, G; Ushikoshi, H; Yamaki, T; Yasuda, S | 1 |
| Amour, J; Bienengraeber, MW; Billstrom, AR; Brzezinska, AK; Kersten, JR; Krolikowski, JG; Pratt, PF; Warltier, DC; Weihrauch, D; Zielonka, J | 1 |
| Fujiwara, H; Fujiwara, T; Iwasa, M; Kawamura, I; Kobayashi, H; Minatoguchi, S; Nagashima, K; Narentuoya, B; Nishigaki, K; Sumi, S; Takemura, G; Ushikoshi, H; Yamaki, T; Yasuda, S | 1 |
| Andjelkovic, N; Davidovic, G; Djuric, DM; Jakovljevic, VLj; Jankovic, S; Milanovic, Z; Novokmet, S | 1 |
| Erikson, JM; Lao, S; Wilson, BS; Xu, X; Zhang, JQ; Zhao, W | 1 |
| Chen, CC; Lee, TM; Lin, CC | 1 |
| Alizadeh, AM; Faghihi, M; Imani, A; Niaraki, SS; Sadr, SS | 1 |
| Aoyama, T; Hattori, A; Iwasa, M; Kobayashi, H; Minatoguchi, S; Nishigaki, K; Sumi, S; Takemura, G; Ushikoshi, H; Yamada, Y; Yamaki, T; Yasuda, S | 1 |
| Dai, X; Kharbanda, RK; Li, J; Manlhiot, C; Redington, A; Steensrud, T; Tropak, M | 1 |
| Ebel, D; Frädorf, J; Hollmann, MW; Huhn, R; Preckel, B; Schlack, W; Toma, O; Weber, NC; Wingert, N | 1 |
| Lowman, JD; Pittman, RN; Tevald, MA | 1 |
| Chen, M; Huo, Y; Li, J; Lou, L; Pan, C; Singh, G; Wang, S; Wu, A; Zhang, D; Zhao, M | 1 |
| Ge, ZD; Hirata, N; Ionova, IA; Kersten, JR; Pieper, GM; Pratt, PF; Pravdic, D; Vásquez-Vivar, J; Vladic, N; Warltier, DC | 1 |
| Akula, A; Challa, SR; Gopal, PN; Metla, S | 1 |
| Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y | 1 |
| Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K | 1 |
| Akasaki, Y; Araki, S; Hanatani, S; Izumiya, Y; Nakagata, N; Ogawa, H; Rokutanda, T; Takeo, T; Usuku, H; Walsh, K | 1 |
| Das, B; Sarkar, C | 1 |
| Meira, EF; Moreira, CM; Padilha, AS; Stefanon, I; Vassallo, DV; Vestena, L | 1 |
| Bonios, MJ; Charitos, E; Diakos, N; Lazaris, N; Malliaras, K; Nanas, JN; Papalois, A; Papazoglou, P; Pierrakos, CN; Pozios, IA; Terrovitis, JV; Tsolakis, EJ; Venetsanakos, J | 1 |
| Cai, A; Dong, Y; Feng, Y; Huang, Y; Mai, W; Qiu, R; Rao, S; Yu, D; Zheng, D; Zhou, Y | 1 |
| Arnaud, C; Demenge, P; Godin-Ribuot, D; Joyeux, M; Lamontagne, D; Ribuot, C | 1 |
| Bauer, WR; Bauersachs, J; Ertl, G; Fraccarollo, D; Galuppo, P; Haase, A; Hiller, KH; Hu, K; Nahrendorf, M; Schweizer, G | 1 |
| Andrew, P; Brunner, F; Maier, R; Mayer, B; Wölkart, G; Zechner, R | 1 |
| Boekstegers, P; Dimmeler, S; Feron, O; Hinkel, R; Horstkotte, J; Kreuzpointner, R; Kupatt, C; Müller, F; Raake, P; Sandner, T; Vachenauer, R | 1 |
| Dietz, V; Kapitza, J; Lee, CH; Niroomand, F; Tiefenbacher, CP | 1 |
| Arai, M; Chen, X; Fujiwara, H; Lu, C; Minatoguchi, S; Misao, Y; Takemura, G; Uno, Y; Wang, N | 1 |
| Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Minamino, T; Node, K; Ogita, H; Sanada, S; Soma, M; Takashima, S | 1 |
| Headrick, JP; Peart, J | 1 |
| Ashitkov, T; Ballinger, S; Birnbaum, Y; Motamedi, M; Uretsky, BF | 1 |
| Menon, V | 1 |
| Blatt, A; Cotter, G; Golick, A; Hendler, A; Kaluski, E; Krakover, R; Milo, O; Salah, A; Vered, Z | 1 |
| Gaballa, M; Goldman, S; Thai, H; Wollmuth, J | 1 |
| Akula, A; Veeravalli, KK | 1 |
| Harada, M; Kitaura, Y; Komuro, I; Masaya, M; Minamino, T; Nagai, T; Sugaya, T; Terasaki, F; Toko, H; Zou, Y | 1 |
| Chen, JK; Hung, LM; Su, MJ | 1 |
| Andriantsitohaina, R; Diebolt, M; Ralay Ranaivo, H; Schott, C | 1 |
| Andriantsitohaina, R; Diebolt, M; Ralay Ranaivo, H | 1 |
| Boekstegers, P; Bouzin, C; Daneau, G; Dessy, C; Feron, O; Hinkel, R; Kupatt, C; Raake, P | 1 |
| Cohen, MV; Cui, L; Downey, JM; Krieg, T; Proctor, JB; Yang, XM | 1 |
| Ahluwalia, A; Foster, P; Hobbs, A; Prescott, C; Scotland, R | 1 |
| Gaballa, MA; Goldman, S; Spooner, PH; Thai, HM | 1 |
| Dendorfer, A; Dominiak, P; Heep, A; Klein, HH; Richardt, G; Schutt, M; Tempel, K; Weidtmann, B; Wolfrum, S | 1 |
| Bajović, BV; Durić, DM; Jakovljević, VLj; Mujović, VM; Novokmet, SS | 1 |
| Pereira, RB; Sartório, CL; Stefanon, I; Vassallo, DV | 1 |
| Chih, CL; Huang, CH; Huang, SS; Hung, WC; Lin, SM; Tsai, SK | 1 |
| Berges, A; Timmermans, JP; Van Nassauw, L; Vrints, C | 1 |
| Baxter, GF; Hamid, SA | 1 |
| Amanpour, S; Dehpour, AR; Ebrahimi, F; Hajrasouliha, AR; Jabehdar-Maralani, P; Mirkhani, SH; Shafaroodi, H; Tavakoli, S | 1 |
| Nasyrov, AG; Rakhmatullina, FF; Zefirov, AL | 1 |
| Bianchi, PR; Giuberti, K; Gumz, BP; Stefanon, I | 1 |
| Kim, HH; Liao, JK; Noma, K; Oyama, N; Rikitake, Y; Satoh, M; Wang, CY | 1 |
| Bullard, AJ; Yellon, DM | 1 |
| Hiroi, T; Ishii, M; Kiuchi, Y; Shimizu, S; Wajima, T | 1 |
| Chakravarty, S; Dugar, S; Kerr, I; Li, Z; Ma, JY; Protter, AA; Schreiner, G | 1 |
| Chiari, PC; Kersten, JR; Krolikowski, JG; Pagel, PS; Pratt, PF; Wang, C; Warltier, DC; Weihrauch, D | 1 |
| Ferreira, LF; Hageman, KS; Hahn, SA; Musch, TI; Padilla, DJ; Poole, DC; Williams, J | 1 |
| Aksulu, HE; Deniz, E; Sahna, E | 1 |
| Arai, M; Bao, N; Chen, XH; Fujiwara, H; Kobayashi, H; Maruyama, R; Minatoguchi, S; Misao, Y; Onogi, H; Takemura, G; Uno, Y; Yamaki, T; Yasuda, S | 1 |
| Almeida, AP; Araújo, CA; Caliari, MV; Ferreira, AJ; Jacoby, BA; Macedo, FA; Santos, RA; Silva, GA | 1 |
| Blatt, A; Hendler, A; Kaluski, E; Uriel, N | 1 |
| Baxter, GF; Bower, HS; Hamid, SA | 1 |
| Kukreja, RC | 1 |
| Czibik, G; Flatebø, T; Ruusalepp, A; Vaage, J; Valen, G | 1 |
| Losano, G; Mancardi, D; Pagliaro, P; Penna, C; Rastaldo, R | 1 |
| Chen, WL; Fu, Y; Moore, PK; Wang, Z; Zhu, YZ | 1 |
| Chao, J; Chao, L; Yin, H | 1 |
| Abbate, A; Brown, WR; Das, A; Hoke, NN; Houser, JE; Kukreja, RC; Mudrick, CA; Prabhakar, S; Qureshi, IZ; Roy, SK; Salloum, FN | 1 |
| Akita, Y; Imamura, H; Iwasaka, T; Matsuhisa, S; Moriguchi, A; Okazaki, T; Otani, H; Sato, D; Yamashita, K | 1 |
| Cui, F; Wang, YP; Yang, CY; Zhang, LP; Zhang, Y | 1 |
| Hartman, JC | 1 |
| Neild, GH; Patel, VC; Woolfson, RG; Yellon, DM | 1 |
| Kaeffer, N; Richard, V; Thuillez, C; Tron, C | 1 |
| Neild, GH; Patel, VC; Singh, KJ; Woolfson, RG; Yellon, DM | 1 |
| Arnal, JF; el Amrani, AI; Michel, JB | 1 |
| Carretero, OA; Liu, YH; Sabbath, HN; Sharov, VG; Sigmon, DH; Yang, XP | 1 |
| Hashizume, Y; Nasa, Y; Ohaku, H; Sanbe, A; Takeo, S; Toyoshima, H | 1 |
| Antunes, E; Costa, SK; de Nucci, G; Hyslop, S; Metze, K; Moreno Júnior, H; Nathan, LP; Zatz, R | 1 |
| Funaya, H; Hori, M; Kitakaze, M; Kosaka, H; Minamino, T; Node, K | 1 |
| Hori, M; Kitakaze, M; Kosaka, H; Minamino, T; Mori, H; Node, K | 1 |
| Cohen, MV; Downey, JM; Liu, GS; Weinbrenner, C | 1 |
| Hori, M; Hoshida, S; Kawahara, K; Kuzuya, T; Yamashita, N | 1 |
| de Lima, RJ; Madi, K; Marques, NM; Paes, Lda S; Reis, Ade A; Xavier-Vidal, R | 1 |
| Frohlich, ED; Fujimori, T; Matsuoka, H; Ono, H; Ono, Y | 1 |
| Gaballa, MA; Goldman, S; Hoover, CA; Raya, TE | 1 |
| Brown, M; Emani, VR; Krottapalli, K; Kukreja, RC; Ockaili, R; Okubo, S | 1 |
| Jung, O; Jung, W; Linz, W; Malinski, T; Schoelkens, BA; Wiemer, G | 1 |
| Cohen, MV; Downey, JM; Heusch, G; Liu, GS; Nakano, A | 1 |
| Gaudette, GR; Horimoto, H; Krukenkamp, IB; Saltman, AE | 1 |
| Bernareggi, M; Berti, F; Colonna, VD; Manfredi, B; Rossoni, G | 1 |
| Baxter, GF; Ebrahim, Z; Yellon, DM | 1 |
| Asakura, M; Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Mori, H; Node, K; Sakata, Y; Sanada, S; Shinozaki, Y; Tada, M; Takashima, S | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Mori, H; Node, K; Sakata, Y; Sanada, S; Shinozaki, Y; Tada, M; Takashima, S | 1 |
| Deng, HW; Li, YJ; Lu, R; Peng, J | 1 |
| Das, DK; Hattori, R; Maulik, N; Otani, H | 1 |
2 review(s) available for ng-nitroarginine methyl ester and Cardiovascular Stroke
| Article | Year |
|---|---|
[INVOLVEMENT OF NITRIC OXIDE CYNTHASE IN THE EARLY PHASE OF THE HEART ISCHEMIC PRECONDITIONING].
Topics: Animals; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrites | 2016 |
Nitric oxide synthase inhibitors in post-myocardial infarction cardiogenic shock--an update.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Enzyme Inhibitors; Humans; Myocardial Infarction; Myocardial Revascularization; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Risk Assessment; Shock, Cardiogenic | 2006 |
1 trial(s) available for ng-nitroarginine methyl ester and Cardiovascular Stroke
| Article | Year |
|---|---|
LINCS: L-NAME (a NO synthase inhibitor) in the treatment of refractory cardiogenic shock: a prospective randomized study.
Topics: Aged; Enzyme Inhibitors; Female; Humans; Intra-Aortic Balloon Pumping; Male; Myocardial Infarction; Myocardial Revascularization; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prospective Studies; Shock, Cardiogenic; Survival Analysis; Treatment Outcome | 2003 |
119 other study(ies) available for ng-nitroarginine methyl ester and Cardiovascular Stroke
| Article | Year |
|---|---|
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection through the purinergic P2Y
Topics: Adenosine Triphosphate; Animals; Cyclic GMP-Dependent Protein Kinases; Erythrocytes; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Soluble Guanylyl Cyclase; ST Elevation Myocardial Infarction | 2022 |
The Role of NO Synthase in the Infarct-Limiting Effect of Urgent and Chronic Adaptation to Normobaric Hypoxia.
Topics: Animals; Hypoxia; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 2023 |
Nicorandil reversed homocysteine-induced coronary microvascular dysfunction via regulating PI3K/Akt/eNOS pathway.
Topics: Animals; Cell Survival; Cells, Cultured; Chromones; Endothelial Cells; Homocysteine; Humans; Hyperhomocysteinemia; Hypoxia; Male; Mice; Microcirculation; Morpholines; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Plant Lectins; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Ventricular Function, Left | 2020 |
Translocator Protein Modulation by 4'-Chlorodiazepam and NO Synthase Inhibition Affect Cardiac Oxidative Stress, Cardiometabolic and Inflammatory Markers in Isoprenaline-Induced Rat Myocardial Infarction.
Topics: Animals; Benzodiazepinones; Biomarkers; Carrier Proteins; Enzyme Inhibitors; Glutathione Peroxidase; Homocysteine; Isoproterenol; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Rats, Wistar; Receptors, GABA-A; Superoxide Dismutase; Troponin T; Tumor Necrosis Factor-alpha | 2021 |
Aucubin Protects against Myocardial Infarction-Induced Cardiac Remodeling via nNOS/NO-Regulated Oxidative Stress.
Topics: Animals; Cell Line; Disease Models, Animal; Echocardiography; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Iridoid Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Thioredoxins; Ventricular Remodeling | 2018 |
Cardioprotective and anti-apoptotic effects of Potentilla reptans L. root via Nrf2 pathway in an isolated rat heart ischemia/reperfusion model.
Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NF-E2-Related Factor 2; NG-Nitroarginine Methyl Ester; Plant Extracts; Plant Roots; Potentilla; Rats; Rats, Wistar; Reactive Oxygen Species | 2018 |
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
Topics: Animals; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Structure-Activity Relationship; Vascular Endothelial Growth Factor B | 2019 |
HSPA12B attenuates cardiac dysfunction and remodelling after myocardial infarction through an eNOS-dependent mechanism.
Topics: Animals; Apoptosis; Fibrosis; Heart; HSP70 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-bcl-2; Vascular Endothelial Growth Factor A; Ventricular Remodeling | 2013 |
Sivelestat attenuates myocardial reperfusion injury during brief low flow postischemic infusion.
Topics: Animals; Aorta; Cardiotonic Agents; Cattle; Coronary Circulation; Creatine Kinase; Electron Spin Resonance Spectroscopy; Endothelial Cells; Glycine; Heart Ventricles; In Vitro Techniques; Male; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfonamides; Superoxides; Vasoconstriction; Ventricular Function, Left | 2013 |
Pyridostigmine prevents peripheral vascular endothelial dysfunction in rats with myocardial infarction.
Topics: Animals; Coronary Vessels; Endothelium, Vascular; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Vasodilation; Vasodilator Agents | 2014 |
Regulation of MMP/TIMP by HUVEC transplantation attenuates ventricular remodeling in response to myocardial infarction.
Topics: Animals; Enzyme Inhibitors; Female; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-3; Ventricular Remodeling | 2014 |
Nebivolol protects against myocardial infarction injury via stimulation of beta 3-adrenergic receptors and nitric oxide signaling.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Apoptosis; Arteries; Benzopyrans; Blood Pressure; Echocardiography; Ethanolamines; Heart; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Nebivolol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Propanolamines; Receptors, Adrenergic, beta-3; Signal Transduction | 2014 |
Role of atrial natriuretic Peptide in oxytocin induced cardioprotection.
Topics: Animals; Atrial Natriuretic Factor; Cardiotonic Agents; Enzyme Inhibitors; Hormone Antagonists; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Oxytocics; Oxytocin; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Vasotocin | 2015 |
Ouabain induces nitric oxide release by a PI3K/Akt-dependent pathway in isolated aortic rings from rats with heart failure.
Topics: Animals; Aorta, Thoracic; Heart Failure; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Phenylephrine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar | 2015 |
Inhibition of Rho-kinase by fasudil restores the cardioprotection of ischemic postconditioninng in hypercholesterolemic rat heart.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Apoptosis; Cholesterol; Coronary Vessels; Hypercholesterolemia; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Wistar; rho-Associated Kinases; Wortmannin | 2014 |
Cardioprotective effects of low-dose combination therapy with rosuvastatin and fasudil in the isolated rat heart.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Calcium Channel Blockers; Cardiotonic Agents; Drug Synergism; Enzyme Inhibitors; Fluorobenzenes; Heart; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrimidines; Rats; Rats, Wistar; Rosuvastatin Calcium; Sulfonamides; Ventricular Function, Left | 2014 |
Enhanced nitric oxide bioavailability in coronary arteries prevents the onset of heart failure in rats with myocardial infarction.
Topics: Acetylcholine; Animals; Biological Availability; Coronary Occlusion; Coronary Vessels; Endothelium, Vascular; Heart Failure; Humans; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Vasodilation; Vasodilator Agents | 2015 |
Inhibition of the nitric oxide/cyclic guanosine monophosphate pathway limited the cardioprotective effect of post-conditioning in hearts with apical myocardial infarction.
Topics: Animals; Guanosine Monophosphate; Ischemic Postconditioning; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Signal Transduction | 2015 |
Sevoflurane post-conditioning reduces rat myocardial ischemia reperfusion injury through an increase in NOS and a decrease in phopshorylated NHE1 levels.
Topics: Anesthetics, Inhalation; Animals; Autophagy; Blotting, Western; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Heart; In Vitro Techniques; Ischemic Postconditioning; Male; Methyl Ethers; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phagosomes; Phosphorylation; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sevoflurane; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers | 2015 |
SIRT1 protects against myocardial ischemia-reperfusion injury via activating eNOS in diabetic rats.
Topics: Acetylation; Animals; Apoptosis; Blotting, Western; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diet, High-Fat; Enzyme Inhibitors; Genetic Vectors; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sirtuin 1; Superoxide Dismutase; Superoxides; Up-Regulation; Ventricular Function, Left | 2015 |
[INVOLVEMENT OF NO-SYNTHASE IN THE INFARCT REDUCING EFFECT OF CONTINUOUS CHRONIC NORMOBARTC HYPOXTA].
Topics: Animals; Hypoxia; Ischemic Preconditioning, Myocardial; Isothiuronium; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Wistar | 2015 |
Myocardial triggers involved in activation of remote ischaemic preconditioning.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Heart; Hindlimb; Hydrogen Peroxide; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Mitochondria; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Parasympathetic Nervous System; Phosphorylation; Potassium Channels; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Vagus Nerve | 2016 |
Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Connexin 43; Enzyme Inhibitors; Gap Junctions; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Phosphorylation; Protein Kinase C-epsilon; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine | 2016 |
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproterenol; Male; Maleimides; Melatonin; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; p38 Mitogen-Activated Protein Kinases; Propranolol; Protein Kinase C; Quinoxalines; Rats; Rats, Wistar; Receptors, Melatonin; Tryptamines | 2008 |
Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart.
Topics: Animals; Cardiotonic Agents; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Lithium Chloride; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Recovery of Function; Ventricular Function, Left; Ventricular Pressure | 2008 |
The mechanism of the late preconditioning effect of 3-nitropropionic acid.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase, MB Form; Electrocardiography; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Ischemic Preconditioning, Myocardial; KATP Channels; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitro Compounds; Potassium Channel Blockers; Propionates; Rats; Rats, Wistar | 2008 |
Simvastatin reduces myocardial infarct size via increased nitric oxide production in normocholesterolemic rabbits.
Topics: Animals; Cholesterol; Coronary Vessels; Enzyme Inhibitors; Heart; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rabbits; Simvastatin | 2009 |
Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning.
Topics: Anesthetics; Animals; Benzoquinones; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Endothelial Cells; Enzyme Inhibitors; Heart Rate; HSP90 Heat-Shock Proteins; Immunoprecipitation; Ischemic Preconditioning, Myocardial; Lactams, Macrocyclic; Luminescence; Macrolides; Male; Microscopy, Confocal; Myocardial Infarction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ozone; Rabbits; Signal Transduction | 2009 |
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Topics: Androstadienes; Anilides; Animals; Blood Glucose; Blotting, Western; Decanoic Acids; Disease Models, Animal; Enzyme Activation; Hemodynamics; Hydroxy Acids; Hypoglycemic Agents; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Pioglitazone; Potassium Channel Blockers; Potassium Channels; PPAR gamma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rabbits; Thiazolidinediones; Time Factors; Ventricular Function, Left; Wortmannin | 2009 |
Human platelets perfusion through isolated guinea-pig heart: the effects on coronary flow and oxidative stress markers.
Topics: Animals; Biomarkers; Blood Platelets; Coronary Circulation; Female; Guinea Pigs; Heart; Humans; In Vitro Techniques; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Perfusion; Platelet-Rich Plasma | 2009 |
Effects of exercise and L-arginine on ventricular remodeling and oxidative stress.
Topics: Animals; Arginine; Echocardiography; Enzyme Inhibitors; Free Radicals; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Oxidative Stress; Physical Conditioning, Animal; Polymerase Chain Reaction; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Analysis, DNA; Survival Analysis; Ventricular Remodeling | 2010 |
17beta-Estradiol decreases vulnerability to ventricular arrhythmias by preserving connexin43 protein in infarcted rats.
Topics: Animals; Arrhythmias, Cardiac; Body Weight; Connexin 43; Echocardiography; Electrophysiological Phenomena; Estradiol; Estrogens; Female; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats; Rats, Wistar; Uterus | 2010 |
Noradrenaline protects in vivo rat heart against infarction and ventricular arrhythmias via nitric oxide and reactive oxygen species.
Topics: Adrenergic alpha-Agonists; Animals; Arrhythmias, Cardiac; Cyclic N-Oxides; Ischemic Preconditioning, Myocardial; Male; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Rats; Rats, Wistar; Reactive Oxygen Species; Spin Labels | 2011 |
Postconditioning effect of granulocyte colony-stimulating factor is mediated through activation of risk pathway and opening of the mitochondrial KATP channels.
Topics: Androstadienes; Animals; Decanoic Acids; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Granulocyte Colony-Stimulating Factor; Heart; Hydroxy Acids; KATP Channels; Male; Mitochondria, Heart; Models, Animal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rabbits; Reperfusion Injury; Signal Transduction; Wortmannin | 2010 |
Pretreatment with the nitric oxide donor SNAP or nerve transection blocks humoral preconditioning by remote limb ischemia or intra-arterial adenosine.
Topics: Adenosine; Animals; Enzyme Inhibitors; Femoral Nerve; Hindlimb; Injections, Intra-Arterial; Ischemia; Ischemic Preconditioning; Male; Models, Animal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Rabbits; S-Nitroso-N-Acetylpenicillamine; Signal Transduction | 2010 |
Sevoflurane-induced preconditioning: impact of protocol and aprotinin administration on infarct size and endothelial nitric-oxide synthase phosphorylation in the rat heart in vivo.
Topics: Anesthetics, Inhalation; Animals; Aprotinin; Blotting, Western; Cardiotonic Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hemodynamics; Hemostatics; Ischemic Preconditioning, Myocardial; Male; Methyl Ethers; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Alveoli; Rats; Rats, Wistar; Sevoflurane | 2010 |
Skeletal muscle arteriolar function following myocardial infarction: Analysis of branch-order effects.
Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Female; Heart Rate; Muscle Contraction; Muscle, Skeletal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Vasodilation; Ventricular Dysfunction, Left | 2011 |
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation | 2011 |
Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia.
Topics: Analysis of Variance; Animals; Biopterins; Calcium; Disease Models, Animal; Enzyme Inhibitors; GTP Cyclohydrolase; Humans; Hyperglycemia; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Time Factors; Ultrasonography; Ventricular Function, Left | 2011 |
Partial role of nitric oxide in infarct size limiting effect of quercetin and rutin against ischemia-reperfusion injury in normal and diabetic rats.
Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Quercetin; Rats; Rats, Wistar; Rutin | 2011 |
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Hydroxy Acids; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion Injury; Superoxides; Tetrazoles; Theophylline | 2011 |
Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Biopterins; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; GTP Cyclohydrolase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pterins; Recovery of Function; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Ventricular Function, Left | 2011 |
Akt1-mediated skeletal muscle growth attenuates cardiac dysfunction and remodeling after experimental myocardial infarction.
Topics: Animals; Enzyme Inhibitors; Fibroblast Growth Factor 1; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Muscle, Skeletal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Signal Transduction; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Left; Ventricular Remodeling | 2012 |
Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart?
Topics: Anesthesia; Animals; Decanoic Acids; Electrocardiography; Energy Metabolism; Enzyme Inhibitors; Heart; Hemodynamics; Hormone Antagonists; Hydroxy Acids; Ischemic Preconditioning; KATP Channels; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Oxytocin; Potassium Channel Blockers; Rabbits; Survival; Vasotocin | 2012 |
Tension cost correlates with mechanical and biochemical parameters in different myocardial contractility conditions.
Topics: Animals; Desoxycorticosterone; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hypertension; Male; Myocardial Contraction; Myocardial Infarction; Nephrectomy; NG-Nitroarginine Methyl Ester; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Function, Left; Ventricular Myosins | 2012 |
Effects of L-NAME on coronary blood flow, infarct size and the extent of the no-reflow phenomenon.
Topics: Animals; Blood Flow Velocity; Coronary Circulation; Enzyme Inhibitors; Myocardial Infarction; NG-Nitroarginine Methyl Ester; No-Reflow Phenomenon; Swine; Treatment Outcome | 2013 |
SDF-1α upregulation by atorvastatin in rats with acute myocardial infarction via nitric oxide production confers anti-inflammatory and anti-apoptotic effects.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Atorvastatin; Benzylamines; Chemokine CXCL12; Coronary Vessels; Cyclams; Heptanoic Acids; Heterocyclic Compounds; Ligation; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; STAT3 Transcription Factor; Up-Regulation | 2012 |
Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
Topics: Analysis of Variance; Animals; Camphanes; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; Fever; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Time Factors | 2002 |
Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study.
Topics: Animals; Disease Models, Animal; Hydralazine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.
Topics: Animals; Calcium; Cyclic GMP; Enzyme Inhibitors; Homeostasis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III | 2003 |
VEGF165 transfection decreases postischemic NF-kappa B-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation.
Topics: Animals; Endothelial Growth Factors; Enzyme Inhibitors; Inflammation; Intercellular Signaling Peptides and Proteins; Liposomes; Lymphokines; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Swine; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Reduction of myocardial infarct size by fluvastatin.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclic GMP; Echocardiography, Doppler, Pulsed; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart Rate; Hydrogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Inbred WF; Ventricular Function, Left | 2003 |
Quinaprilat reduces myocardial infarct size involving nitric oxide production and mitochondrial KATP channel in rabbits.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Decanoic Acids; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hydroxyl Radical; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channel Blockers; Potassium Channels; Rabbits; Tetrahydroisoquinolines | 2003 |
Eicosapentaenoic acid reduces myocardial injury induced by ischemia and reperfusion in rabbit hearts.
Topics: Animals; Cardiotonic Agents; Charybdotoxin; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Hemodynamics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channel Blockers; Rabbits; Time Factors | 2003 |
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.
Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine | 2003 |
Reduction of infarct size by short-term pretreatment with atorvastatin.
Topics: Animals; Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Pyrroles; Rats; Rats, Sprague-Dawley | 2003 |
Cardiogenic shock: have we really found the magic potion?
Topics: Adult; Age Factors; Aged; Enzyme Inhibitors; Humans; Intra-Aortic Balloon Pumping; Middle Aged; Myocardial Infarction; Myocardial Revascularization; NG-Nitroarginine Methyl Ester; Nitric Oxide; Randomized Controlled Trials as Topic; Shock, Cardiogenic | 2003 |
Angiotensin subtype 1 rReceptor (AT1) blockade improves vasorelaxation in heart failure by up-regulation of endothelial nitric-oxide synthase via activation of the AT2 receptor.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cattle; Cells, Cultured; Enzyme Inhibitors; Heart Failure; Hemodynamics; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation; Vascular Resistance; Ventricular Function, Left | 2003 |
Involvement of nitric oxide and prostaglandin pathways in the cardioprotective actions of bradykinin in rats with experimental myocardial infarction.
Topics: Animals; Aspirin; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Injections, Intravenous; Lisinopril; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Peptides; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts | 2004 |
Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium.
Topics: Angiotensin II; Animals; Arterioles; Capillaries; Chemotaxis, Leukocyte; Collateral Circulation; Cytokines; Enzyme Inhibitors; Granulocytes; Macrophages; Male; Mice; Mice, Knockout; Myocardial Infarction; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Sarcoma 180; T-Lymphocytes; Ventricular Remodeling | 2004 |
Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Creatine Kinase; Gene Expression; Heart Rate; L-Lactate Dehydrogenase; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2004 |
Polyphenolic compounds from Cognac induce vasorelaxation in vitro and decrease post-ischaemic cardiac infarction after an oral administration.
Topics: Administration, Oral; Alcoholic Beverages; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Flavonoids; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Myocardial Infarction; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenols; Polyphenols; Rats; Rats, Wistar; Vasodilation | 2004 |
Wine polyphenols induce hypotension, and decrease cardiac reactivity and infarct size in rats: involvement of nitric oxide.
Topics: Administration, Oral; Aldehydes; Animals; Blood Pressure; Blotting, Western; Carbachol; Coronary Circulation; Drug Administration Schedule; Drug Therapy, Combination; Flavonoids; France; Heart Rate; Heart Ventricles; Hypotension; Isoproterenol; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Phenols; Polyphenols; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Ventricular Function; Ventricular Pressure; Wine | 2004 |
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.
Topics: Animals; Benzoquinones; Calcineurin; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Genetic Therapy; Genetic Vectors; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Liposomes; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinones; Sus scrofa; Transfection; Umbilical Veins; Vascular Endothelial Growth Factor A | 2004 |
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways.
Topics: Animals; Calcium Channel Blockers; Decanoic Acids; Enzyme Inhibitors; Female; Glyburide; Hemodynamics; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Potassium Channels; Rabbits; Signal Transduction; Time Factors | 2004 |
Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide.
Topics: Acetylcholine; Animals; Atrial Natriuretic Factor; Barium; Coronary Circulation; Drug Evaluation, Preclinical; Endothelium, Vascular; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Peptide Fragments; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Signal Transduction; Vasodilation; Vasodilator Agents | 2004 |
Thyroid hormone analog, DITPA, improves endothelial nitric oxide and beta-adrenergic mediated vasorelaxation after myocardial infarction.
Topics: Acetylcholine; Animals; Cattle; Cells, Cultured; Coronary Vessels; Diiodothyronines; Endothelium, Vascular; Heart Failure; Hemodynamics; Isoproterenol; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasodilator Agents; Ventricular Function, Left | 2004 |
Simvastatin acutely reduces myocardial reperfusion injury in vivo by activating the phosphatidylinositide 3-kinase/Akt pathway.
Topics: Androstadienes; Animals; Cholesterol; Coronary Stenosis; Drug Administration Schedule; Injections, Intravenous; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Simvastatin; Time Factors; Wortmannin | 2004 |
[Effects of platelet single passage on coronary circulation in the isolated guinea-pig heart: focus on the L-arginine: nitric oxide system].
Topics: Animals; Arginine; Blood Flow Velocity; Blood Platelets; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 2003 |
Differences in tail vascular bed reactivity in rats with and without heart failure following myocardial infarction.
Topics: Animals; Dose-Response Relationship, Drug; Heart Failure; Indomethacin; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Tail; Vasoconstriction | 2005 |
Effect of desflurane-induced preconditioning following ischemia-reperfusion on nitric oxide release in rabbits.
Topics: Anesthetics, Inhalation; Animals; Creatine Kinase; Desflurane; Enzyme Inhibitors; Hemodynamics; Isoflurane; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Tachycardia, Ventricular; Ventricular Fibrillation | 2004 |
Role of nitric oxide during coronary endothelial dysfunction after myocardial infarction.
Topics: Adenosine; Amidines; Animals; Benzylamines; Bradykinin; Coronary Circulation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Heart; Immunohistochemistry; In Vitro Techniques; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Proadifen; Rats; Rats, Wistar; RNA, Messenger; Superoxides | 2005 |
Adrenomedullin limits reperfusion injury in experimental myocardial infarction.
Topics: Adrenomedullin; Animals; Coronary Circulation; Extracellular Signal-Regulated MAP Kinases; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
Cholestatic liver disease modulates susceptibility to ischemia/reperfusion-induced arrhythmia, but not necrosis and hemodynamic instability: the role of endogenous opioid peptides.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cholestasis, Intrahepatic; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Infarction; Naltrexone; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2005 |
The course of experimental myocardial infarction under conditions of Suppressed and enhanced NO synthesis.
Topics: Animals; Arginine; Enzyme Inhibitors; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats | 2005 |
Myocardial infarction increases reactivity to phenylephrine in isolated aortic rings of ovariectomized rats.
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Female; In Vitro Techniques; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents | 2006 |
Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; rho-Associated Kinases; Vascular Diseases | 2005 |
Chronic erythropoietin treatment limits infarct-size in the myocardium in vitro.
Topics: Animals; Cardiotonic Agents; Drug Administration Schedule; Enzyme Inhibitors; Erythropoietin; Heart; Hematocrit; In Vitro Techniques; Male; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Rats; Rats, Sprague-Dawley | 2005 |
Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.
Topics: Animals; Anti-Arrhythmia Agents; Arginine; Biopterins; Cyclic GMP; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxy Acids; Male; Malondialdehyde; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Potassium Channels; Rats; Rats, Sprague-Dawley | 2006 |
Selective inhibition of p38alpha MAPK improves cardiac function and reduces myocardial apoptosis in rat model of myocardial injury.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Cardiac Output; Caspase 3; Caspases; Enzyme Inhibitors; Heart; Indoles; Inflammation; Male; Mitogen-Activated Protein Kinase 14; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Stroke Volume; Vasoconstrictor Agents | 2006 |
Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase.
Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Female; Guanidines; Heart Rate; Indazoles; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rabbits; Sex Factors | 2006 |
Muscle microvascular oxygenation in chronic heart failure: role of nitric oxide availability.
Topics: Animals; Blood Vessels; Exercise Tolerance; Heart Failure; Male; Microcirculation; Muscle, Skeletal; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxygen; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2006 |
Nitric oxide synthase inhibition in rats: melatonin reduces blood pressure and ischemia/reperfusion-induced infarct size.
Topics: Animals; Antioxidants; Blood Pressure; Hypertension; Male; Melatonin; Models, Animal; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 2006 |
Edaravone reduces myocardial infarct size and improves cardiac function and remodelling in rabbits.
Topics: Animals; Antipyrine; Blood Pressure; Edaravone; Enzyme Inhibitors; Free Radical Scavengers; Gentisates; Heart Rate; Hydroxybenzoates; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Rabbits; Superoxides; Ventricular Remodeling | 2006 |
The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Imidazoles; Ligation; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Time Factors; Vasoconstriction; Vasodilator Agents; Ventricular Function, Left | 2007 |
Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Androstadienes; Animals; Apoptosis; Cardiotonic Agents; Coronary Circulation; Cytoskeletal Proteins; Enzyme Activation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Microfilament Proteins; Multiprotein Complexes; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Wortmannin | 2007 |
Cardiovascular protection with sildenafil following chronic inhibition of nitric oxide synthase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Antihypertensive Agents; Carbolines; Cardiomyopathies; Cardiovascular Agents; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Doxorubicin; Endothelium, Vascular; Enzyme Inhibitors; Erectile Dysfunction; Heart Failure; Humans; Hypertension; Hypertension, Pulmonary; Imidazoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents; Ventricular Remodeling | 2007 |
Myocardial protection evoked by hyperoxic exposure involves signaling through nitric oxide and mitogen activated protein kinases.
Topics: Animals; Coronary Circulation; Enzyme Inhibitors; Flavonoids; Hyperoxia; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrazoles; Pyridines; Signal Transduction; Ventricular Function, Left; Ventricular Pressure | 2007 |
Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Decanoic Acids; Hydroxy Acids; Mitochondria, Heart; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Bradykinin B2; Signal Transduction | 2007 |
Cardioprotective effects of nitric oxide-aspirin in myocardial ischemia-reperfused rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Inhibitors; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Ventricular Dysfunction, Left; Ventricular Function, Left | 2007 |
Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion.
Topics: Adenoviridae; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Enzyme Inhibitors; Gene Expression; Gene Transfer Techniques; Heart Function Tests; Heart Ventricles; Hemodynamics; Humans; Kallikreins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocarditis; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Wistar; Receptor, Bradykinin B2; Ventricular Remodeling | 2008 |
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice.
Topics: Animals; Apoptosis; Blotting, Western; Cardiomegaly; Cardiomyopathy, Restrictive; Coronary Vessels; Echocardiography, Doppler; Enzyme Inhibitors; In Situ Nick-End Labeling; Ligation; Male; Mice; Mice, Inbred ICR; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperazines; Pulmonary Edema; Purines; Sildenafil Citrate; Sulfones; Survival Analysis; Vasodilator Agents; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart.
Topics: Aldehydes; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzylamines; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Hypertension; Losartan; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Tiopronin; Up-Regulation; Ventricular Function, Left | 2008 |
Protective effect of polydatin against ischemia/reperfusion injury in rat heart.
Topics: Animals; Glucosides; Heart; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Stilbenes; Superoxide Dismutase | 2008 |
The role of bradykinin and nitric oxide in the cardioprotective action of ACE inhibitors.
Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Heart; Imidazoles; Losartan; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Ramipril; Receptors, Angiotensin; Receptors, Bradykinin; Tetrazoles | 1995 |
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits; Theophylline; Time Factors | 1995 |
Ischemic preconditioning protects against coronary endothelial dysfunction induced by ischemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Coronary Vessels; Endothelium, Vascular; Male; Molsidomine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Serotonin; Vasodilator Agents | 1994 |
Inhibition of nitric oxide limits infarct size in the in situ rabbit heart.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Heart Rate; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits | 1993 |
Atrial natriuretic factor influences in vivo plasma, lung and aortic wall cGMP concentrations differently.
Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Disease Models, Animal; Infusions, Intravenous; Lung; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Renin | 1993 |
Paracrine systems in the cardioprotective effect of angiotensin-converting enzyme inhibitors on myocardial ischemia/reperfusion injury in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arrhythmias, Cardiac; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Hemodynamics; Indomethacin; Male; Myocardial Infarction; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ramipril; Rats; Rats, Inbred Lew; Reperfusion Injury | 1996 |
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
Topics: Animals; Aorta, Thoracic; Cardiac Output, Low; Chronic Disease; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Heart; Isoproterenol; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Norepinephrine; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation | 1996 |
Non-specific inhibitors of nitric oxide synthase cause myocardial necrosis in the rat.
Topics: Animals; Blood Pressure; Coronary Circulation; Enzyme Inhibitors; Male; Myocardial Infarction; Myocardium; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism | 1997 |
Amelioration of ischemia- and reperfusion-induced myocardial injury by 17beta-estradiol: role of nitric oxide and calcium-activated potassium channels.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Dogs; Enzyme Inhibitors; Estradiol; Heart Ventricles; Indomethacin; Ion Channel Gating; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Potassium Channels; Tachycardia, Ventricular; Toxins, Biological | 1997 |
Role of Ca2+-activated K+ channels in the protective effect of ACE inhibition against ischemic myocardial injury.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcium; Cilazapril; Collateral Circulation; Coronary Circulation; Data Interpretation, Statistical; Dogs; Enzyme Inhibitors; Epoprostenol; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channels; Scorpion Venoms; Time Factors; Toxins, Biological | 1998 |
Cyclosporine A limits myocardial infarct size even when administered after onset of ischemia.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cyclosporine; Enzyme Inhibitors; Female; Immunosuppressive Agents; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Perfusion; Rabbits; Tacrolimus | 1998 |
Amelioration by quinapril of myocardial infarction induced by coronary occlusion/reperfusion in a rabbit model of atherosclerosis: possible mechanisms.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arterial Occlusive Diseases; Coronary Artery Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Isoquinolines; Leukocytes; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; P-Selectin; Peroxidase; Quinapril; Rabbits; Receptor, Bradykinin B2; Receptors, Bradykinin; Tetrahydroisoquinolines; Ventricular Fibrillation | 1999 |
[Experimental anatomo-pathologic study in the myocardium of animals with arterial hypertension caused via a nitric oxide synthesis blocker].
Topics: Animals; Enzyme Inhibitors; Fibrosis; Heart Atria; Heart Ventricles; Hypertension; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Time Factors | 1999 |
Apoptosis, coronary arterial remodeling, and myocardial infarction after nitric oxide inhibition in SHR.
Topics: Animals; Apoptosis; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Fibrosis; Hemodynamics; Hypertension; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR | 1999 |
Effects of endothelial and inducible nitric oxide synthases inhibition on circulatory function in rats after myocardial infarction.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hemodynamics; Isoproterenol; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley | 1999 |
Opening of mitochondrial KATP channel induces early and delayed cardioprotective effect: role of nitric oxide.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Decanoic Acids; Diazoxide; Hydroxy Acids; In Vitro Techniques; Ion Channel Gating; Ischemic Preconditioning; Male; Mitochondria; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rabbits; Time Factors | 1999 |
Ischemic preconditioning and infarct mass: the effect of hypercholesterolemia and endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Calcimycin; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Hypercholesterolemia; Ionophores; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Polyethylene Glycols; Potassium Chloride; Rabbits; Superoxide Dismutase; Vasodilation | 2000 |
Exogenous nitric oxide can trigger a preconditioned state through a free radical mechanism, but endogenous nitric oxide is not a trigger of classical ischemic preconditioning.
Topics: Animals; Antioxidants; Enzyme Inhibitors; Female; Free Radicals; Glycine; Heart; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Protein Kinase C; Rabbits; Sulfhydryl Compounds | 2000 |
The role of nitric oxide, K(+)(ATP) channels, and cGMP in the preconditioning response of the rabbit.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arginine; Coronary Circulation; Cyclic GMP; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning; Male; Methylene Blue; Muscle Fibers, Skeletal; Myocardial Infarction; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rabbits | 2000 |
The nitroderivative of aspirin, NCX 4016, reduces infarct size caused by myocardial ischemia-reperfusion in the anesthetized rat.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Creatine Kinase; Cyclic GMP; Fibrinolytic Agents; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; NG-Nitroarginine Methyl Ester; Peroxidase; Platelet Aggregation Inhibitors; Rats; Rats, Wistar | 2001 |
Bradykinin elicits "second window" myocardial protection in rat heart through an NO-dependent mechanism.
Topics: Animals; Blood Flow Velocity; Body Weight; Bradykinin; Coronary Circulation; Coronary Disease; Cytoprotection; Drug Administration Schedule; Hemodynamics; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Sprague-Dawley | 2001 |
Nifedipine limits infarct size via NO-dependent mechanisms in dogs.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dogs; Endothelium; Enzyme Inhibitors; Heart Rate; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Peroxidase | 2001 |
Benidipine, a long-acting Ca channel blocker, limits infarct size via bradykinin- and NO-dependent mechanisms in canine hearts.
Topics: Adrenergic beta-Antagonists; Animals; Bradykinin; Calcium Channel Blockers; Dihydropyridines; Dogs; Enzyme Inhibitors; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase | 2001 |
Involvement of alpha-calcitonin gene-related peptide in monophosphoryl lipid A-induced delayed preconditioning in rat hearts.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Creatine Kinase; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Lipid A; Male; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2002 |
Pharmacological preconditioning with resveratrol: role of nitric oxide.
Topics: Animals; Apoptosis; Enzyme Inhibitors; Gene Expression; Guanidines; Heart Ventricles; Ischemic Preconditioning; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2002 |