Page last updated: 2024-08-23

ng-nitroarginine methyl ester and Cardiomegaly

ng-nitroarginine methyl ester has been researched along with Cardiomegaly in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (20.83)18.2507
2000's31 (43.06)29.6817
2010's24 (33.33)24.3611
2020's2 (2.78)2.80

Authors

AuthorsStudies
Balkan, W; Cai, R; Dulce, RA; Hare, JM; Kanashiro-Takeuchi, RM; Kazmierczak, K; Schally, AV; Sha, W; Takeuchi, LM1
Huang, S; Jia, Z; Niu, Y; Shi, W; Wang, S; Yu, J; Zhang, A; Zhang, Y; Zhou, W1
Abolarinwa, BA; Achile, CJ; Kim, IK; Olaniyi, KS; Olatunji, LA; Usman, TO1
Abo-Elmatty, DM; El-Baz, AA; Ibrahim, A; Mosaad, SM; Moustafa, YM; Zaitone, SA1
Hein, TW; Kuo, L; Lu, G; Ren, Y; Tsai, SH; Xu, X1
Almeida, JF; Alves, GM; Castro, CH; Colugnati, DB; Ferreira, AJ; Macedo, LM; Mendes, EP; Porto, JE; Santos, RA; Sobrinho, DB; Souza, ÁP; Vêncio, EF1
Boe, AE; Eren, M; Ichimura, A; Kamide, CE; McAnally, D; Miyata, T; Murphy, SB; Smith, LH; Terry, D; Vaughan, DE1
Hambly, BD; Lai, YN; McLachlan, CS; Ocsan, RJ; Prabhu, KV1
Jia, Z; Li, J; Liu, J; Qi, Z; Tang, X; Tian, W; Wu, P; Yang, L; Zhang, J; Zhu, M1
Coelho-Filho, OR; Jerosch-Herold, M; Kwong, R; Mitchell, R; Moreno, H; Neilan, TG; Shah, RV1
Cacanyiova, S; Drobna, M; Kristek, F1
Iwao, H; Izumi, Y; Kawaguchi, H; Miura, K; Nakamura, Y; Okamura, T; Osada-Oka, M; Shiota, M; Tanimoto, A; Tawa, M; Yamaguchi, T; Yamazaki, T; Yoshiyama, M1
Lira, VA1
Li, J; Liu, J; Lu, P; Qi, Z; Ren, J; Tian, W; Yang, L; Zhu, M1
Engle, SK; Watson, DE1
Cao, TN; Cordero-Reyes, AM; Gupte, AA; Hamilton, DJ; Li, S; Smith, JA; Torre-Amione, G; Vedula, I; Youker, KA; Zhang, A1
Aslan, M; Olgar, Y; Ozdemir, S; Ozturk, N1
Coffman, TM; Ellison, J; Francois, H; Makhanova, N; Mao, L; Rockman, HA; Ruiz, P1
Bonney, W; Cheema, FH; Gonzalez, AM; Homma, S; Kinnear, C; Liao, JK; Mahmut, N; Martens, TP; Mital, S; Osorio, JC1
McLemore, GR; Ryan, MJ; Stec, DE; Storm, MV; Vera, T1
Adler, GK; Coutinho, P; Guo, C; Lapointe, N; Loutraris, P; Pojoga, LH; Ricchiuti, V; Romero, JR; Stone, JR; Williams, GH; Yao, TM1
Berger, S; Duan, SZ; Frieler, RA; Ivaschenko, CY; Lumeng, CN; Mortensen, RM; Schütz, G; Usher, MG1
Bell, D; Campbell, M; Cosby, SL; Earle, JA; McDermott, BJ; Wang, X1
Baumann, M; Eissler, R; Heemann, U; Kühne, L; Lahmer, T; Lutz, J; Rusai, K; Schmaderer, C; Sollinger, D; Witzke, O1
Buckley, MM; Johns, EJ1
Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I1
Fantinelli, JC; González Arbeláez, LF; Mosca, SM; Pérez Núñez, IA; Schinella, GR1
Dinda, AK; Maulik, SK; Prabhakar, P; Seth, S1
Al Kaabba, A; Khatib, S; Mohammad, M; Siam, A; Zeidan, A1
Asakura, M; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sanada, S; Takashima, S2
Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Minamino, T; Node, K; Ogita, H; Sanada, S; Takashima, S1
Beck, CR; Katovich, MJ; Raizada, MK; Reaves, PY; Wang, HW1
Ishimitu, T; Matsuoka, H; Ono, H; Ono, Y; Saitoh, M1
Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Liao, Y; Minamino, T; Ogai, A; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H1
Wang, YX1
Bell, D; Kelso, EJ; Lamont, VM; McDermott, BJ; McHenry, EM; Nicholls, DP; Rush, LM; Zhao, YY1
Chang, HR; Chen, HI; Hsu, YH; Hu, CT; Liu, CJ1
Al-Shabanah, O; Khattab, MM; Mostafa, A1
Kim, HH; Liao, JK; Noma, K; Oyama, N; Rikitake, Y; Satoh, M; Wang, CY1
Antunes, E; Araujo, EG; De Nucci, G; Faro, R; Guaraldo, AM; Zanfolin, M1
Kim, J; Kitakaze, M; Minamino, T; Mochizuki, N; Myoishi, M; Okada, K; Okazaki, H; Takashima, S; Tsukamoto, O; Wakeno, M1
Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yamashita, T1
Carmeliet, P; Chorianopoulos, E; Elfenbein, A; Eriksson, U; Fu, Q; Hall, AE; Moodie, KL; Moons, L; Palac, RT; Roncal, C; Simons, M; Tirziu, D; Tjwa, M; Zhuang, ZW1
Abbate, A; Brown, WR; Das, A; Hoke, NN; Houser, JE; Kukreja, RC; Mudrick, CA; Prabhakar, S; Qureshi, IZ; Roy, SK; Salloum, FN1
Hou, Y; Matsuo, O; Okada, K; Okamoto, C; Ueshima, S1
Egashira, K; Kadokami, T; Numaguchi, K; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A1
Carretero, OA; Rhaleb, NE; Scicli, AG; Yang, XP1
Grötsch, H; Hropot, M; Klaus, E; Langer, KH; Linz, W; Schölkens, BA; Wiemer, G1
Fujita, H; Itoh, H; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K; Tanaka, M; Uchida, A1
Lantelme, P; Lo, M; Sassard, J1
Adams, MA; Banting, JD; Wiseman, SL1
Li, JS; Schiffrin, EL; Sventek, P1
Egashira, K; Numaguchi, K; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A; Tomita, H; Tsutsui, H; Usui, M1
Egashira, K; Kitabatake, A; Okamoto, H; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A; Tomita, H; Usui, M1
Anderson, NH; Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McPhaden, A; Reid, JL1
Brosnan, MJ; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M; McPhaden, AR; Morton, JJ; Reid, JL1
Cardinal, R; de Champlain, J; K-Laflamme, A; Oster, L1
Anderson, NH; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; Morton, JJ; Reid, JL; Schork, NJ1
Brunner, HR; Formenton, A; Haefliger, JA; Hayoz, D; Meda, P; Nicod, P; Wiesel, P; Zanchi, A1
Bartunek, J; Douglas, PS; Katz, SE; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO1
Antunes, E; Cintra, KA; De Luca, IM; De Nucci, G; de Oliveira, CF; Teixeira, SA1
Egashira, K; Katoh, M; Mitsui, T; Narita, H; Takeshita, A1
Laverty, R; Ledingham, JM; Orange, SJ1
Mandarim-De-Lacerda, CA; Pereira, LM2
Anand-Srivastava, MB; Di Fusco, F1
Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Ogai, A; Papst, PJ; Sakata, Y; Terada, N; Ueda, Y1
Abassi, Z; Brezis, M; Goldfarb, M; Heyman, SN; Rosen, S; Shina, A1
Asakura, M; Asanuma, H; Fukushima, T; Hori, M; Kitakaze, M; Kuzuya, T; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sakata, Y; Sanada, S; Takashima, S; Yamada, J1
Holtz, J; Jäger, D; Müller, SP; Müller-Werdan, U; Pönicke, K; Werdan, K1
Babal, P; Bernatova, I; Hulin, I; Luptak, I; Matuskova, J; Pechanova, O; Simko, F1

Reviews

2 review(s) available for ng-nitroarginine methyl ester and Cardiomegaly

ArticleYear
Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice.
    Neurobiology of aging, 2005, Volume: 26, Issue:3

    Topics: Angiotensin II; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Cardiac Output, High; Cardiomegaly; Cardiovascular System; Enzyme Inhibitors; Estradiol; Hypercholesterolemia; Hyperglycemia; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Phenotype; Simvastatin

2005
Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension.
    Advances in experimental medicine and biology, 1997, Volume: 432

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Susceptibility; Humans; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY

1997

Other Studies

70 other study(ies) available for ng-nitroarginine methyl ester and Cardiomegaly

ArticleYear
Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction.
    American journal of physiology. Heart and circulatory physiology, 2023, 06-01, Volume: 324, Issue:6

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Growth Hormone-Releasing Hormone; Heart Failure; Inflammation; Mice; NG-Nitroarginine Methyl Ester; Stroke Volume; Vascular Endothelial Growth Factor A; Ventricular Function, Left

2023
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS.
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Electrolytes; Endothelial Cells; Glycine; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Kidney Glomerulus; Male; Mice; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proteinuria; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Urine; Vascular Remodeling

2021
Combined oral contraceptive and nitric oxide synthesis inhibition synergistically causes cardiac hypertrophy and exacerbates insulin resistance in female rats.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Animals; Blood Pressure; C-Reactive Protein; Cardiomegaly; Contraceptives, Oral, Combined; Estradiol; Ethinyl Estradiol; Female; Insulin Resistance; Levonorgestrel; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Rats, Wistar; Uric Acid

2017
Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2.
    Chemico-biological interactions, 2017, Jun-25, Volume: 272

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Caspase 3; Celecoxib; Creatine Kinase, MB Form; Disease Models, Animal; DNA Fragmentation; L-Lactate Dehydrogenase; Male; Myeloid Cell Leukemia Sequence 1 Protein; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

2017
Enhanced endothelin-1/Rho-kinase signalling and coronary microvascular dysfunction in hypertensive myocardial hypertrophy.
    Cardiovascular research, 2017, Sep-01, Volume: 113, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arterioles; Cardiomegaly; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilator Agents

2017
Angiotensin II type 1 receptor blockade restores angiotensin-(1-7)-induced coronary vasodilation in hypertrophic rat hearts.
    Clinical science (London, England : 1979), 2013, Volume: 125, Issue:9

    Topics: Angiotensin I; Animals; Cardiomegaly; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Vasodilation

2013
Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence.
    Circulation, 2013, Nov-19, Volume: 128, Issue:21

    Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Cellular Senescence; Drug Interactions; Enzyme Inhibitors; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; para-Aminobenzoates; Piperazines; Rats; Rats, Wistar; Serpin E2; Structure-Activity Relationship; Telomere

2013
Chronic NG-nitro-l-arginine methyl ester (L-NAME) administration in C57BL/6J mice induces a sustained decrease in c-kit positive cells during development of cardiac hypertrophy.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2013, Volume: 64, Issue:6

    Topics: Animals; Cardiomegaly; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Proto-Oncogene Proteins c-kit

2013
Exercise protects against chronic β-adrenergic remodeling of the heart by activation of endothelial nitric oxide synthase.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Cardiomegaly; Fibrosis; Heart; Hemodynamics; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Physical Conditioning, Animal; Proto-Oncogene Proteins c-akt; Receptors, Adrenergic, beta; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transcriptional Activation

2014
Cardiac magnetic resonance assessment of interstitial myocardial fibrosis and cardiomyocyte hypertrophy in hypertensive mice treated with spironolactone.
    Journal of the American Heart Association, 2014, Jun-25, Volume: 3, Issue:3

    Topics: Animals; Cardiac Imaging Techniques; Cardiomegaly; Fibrosis; Heart; Hypertension; Magnetic Resonance Imaging; Mice; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Receptors, Mineralocorticoid; Spironolactone; Stroke Volume

2014
Different effects of 7-nitroindazole and L-NAME administered both individually and together on the cardiovascular system of the rat.
    Physiological research, 2015, Volume: 64, Issue:1

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Carotid Arteries; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats, Inbred SHR; Rats, Wistar; Vascular Remodeling; Vasodilation; Ventricular Remodeling

2015
Noninvasive metabolic syndrome model using an extremely small minipig, the microminipig.
    Journal of pharmacological sciences, 2014, Volume: 126, Issue:2

    Topics: Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Cholesterol, Dietary; Coronary Vessels; Diet, High-Fat; Disease Models, Animal; Drug Discovery; Endothelium, Vascular; Lipoproteins, LDL; Male; Metabolic Syndrome; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Swine; Swine, Miniature

2014
Exercise-induced cardioprotection: more to k‘NO’w.
    Cardiology, 2015, Volume: 130, Issue:3

    Topics: Animals; Blood Pressure; Cardiomegaly; Female; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase

2015
Nitric oxide synthase inhibition abolishes exercise-mediated protection against isoproterenol-induced cardiac hypertrophy in female mice.
    Cardiology, 2015, Volume: 130, Issue:3

    Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Echocardiography; Enzyme Inhibitors; Female; Fibrosis; Isoproterenol; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Physical Conditioning, Animal; Real-Time Polymerase Chain Reaction; Up-Regulation

2015
Natriuretic Peptides as Cardiovascular Safety Biomarkers in Rats: Comparison With Blood Pressure, Heart Rate, and Heart Weight.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 149, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomegaly; Heart Rate; Indoles; Male; Minoxidil; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Size; Peptide Fragments; Prostaglandins F, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Sunitinib; Thyroxine

2016
Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure.
    American journal of physiology. Heart and circulatory physiology, 2016, Mar-15, Volume: 310, Issue:6

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; DNA, Mitochondrial; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Gene Expression; Heart; Heart Failure; Hydrogen Peroxide; Mice; Mitochondria, Heart; Myocardium; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Protein Precursors; Pyruvate Dehydrogenase Complex; Reverse Transcriptase Polymerase Chain Reaction; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Vasoconstrictor Agents

2016
Effects of magnesium supplementation on electrophysiological remodeling of cardiac myocytes in L-NAME induced hypertensive rats.
    Journal of bioenergetics and biomembranes, 2016, Volume: 48, Issue:4

    Topics: Animals; Atrial Remodeling; Calcium; Cardiomegaly; Dietary Supplements; Heart Ventricles; Hypertension; Magnesium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats

2016
A role for the thromboxane receptor in L-NAME hypertension.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:4

    Topics: Albuminuria; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Drinking; Eating; Enzyme Inhibitors; Hypertension, Renal; Isoprostanes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Thromboxane A2, Prostaglandin H2; Renin-Angiotensin System; Sodium, Dietary; Thromboxane B2

2008
Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:9

    Topics: Animals; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Signal Transduction; Simvastatin; Stroke Volume; Ultrasonography

2008
Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:6

    Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Vascular Resistance; Vasoconstriction

2009
Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.
    Endocrinology, 2010, Volume: 151, Issue:3

    Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Caveolin 1; Endothelial Cells; Male; Mice; Mice, Knockout; Molecular Sequence Data; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Signal Transduction

2010
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:9

    Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Fibrosis; Heart; Hypertension; Hypertrophy; Interleukin-4; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; NG-Nitroarginine Methyl Ester; Receptors, Glucocorticoid; Receptors, Mineralocorticoid

2010
Adrenomedullin gene delivery is cardio-protective in a model of chronic nitric oxide deficiency combining pressure overload, oxidative stress and cardiomyocyte hypertrophy.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:3

    Topics: Adrenomedullin; Animals; Atrial Natriuretic Factor; Cardiomegaly; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Humans; Myocytes, Cardiac; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pressure; Rats; Superoxide Dismutase

2010
Hypertension augments cardiac Toll-like receptor 4 expression and activity.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Chemokine CCL2; Heparitin Sulfate; Hypertension; Interleukin-6; Myocardium; NG-Nitroarginine Methyl Ester; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Up-Regulation

2011
Impact of L-NAME on the cardiopulmonary reflex in cardiac hypertrophy.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Caffeine; Cardiomegaly; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Heart Rate; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Sympathetic Nervous System; Thyroxine; Urodynamics

2011
Role of angiotensin-converting enzyme 2 in cardiac hypertrophy induced by nitric oxide synthase inhibition.
    Journal of hypertension, 2011, Volume: 29, Issue:11

    Topics: Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger

2011
Participation of mitochondrial permeability transition pore in the effects of ischemic preconditioning in hypertrophied hearts: role of NO and mitoKATP.
    International journal of cardiology, 2013, Jun-05, Volume: 166, Issue:1

    Topics: Animals; Cardiomegaly; Ischemic Preconditioning, Myocardial; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Treatment Outcome

2013
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:8

    Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genistein; Glutathione; Guanidines; Hydroxyproline; Isoproterenol; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2012
The ability of phosphodiesterase-5 inhibitors sildenafil and ordonafil to reverse L-NAME induced cardiac hypertrophy in the rabbit: possible role of calcineurin and p38.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:9

    Topics: Animals; Calcineurin; Cardiomegaly; Cell Size; Female; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rabbits; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones

2012
Opening of the adenosine triphosphate-sensitive potassium channel attenuates cardiac remodeling induced by long-term inhibition of nitric oxide synthesis: role of 70-kDa S6 kinase and extracellular signal-regulated kinase.
    Journal of the American College of Cardiology, 2002, Sep-04, Volume: 40, Issue:5

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Body Weight; Cardiomegaly; Glyburide; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases

2002
[Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
    Journal of cardiology, 2003, Volume: 41, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Chromans; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Ventricular Remodeling

2003
Long-acting Ca2+ blockers prevent myocardial remodeling induced by chronic NO inhibition in rats.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:4

    Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Kinetics; Male; Mitogen-Activated Protein Kinases; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa

2003
Endothelial-independent prevention of high blood pressure in L-NAME-treated rats by angiotensin II type I receptor antisense gene therapy.
    Experimental physiology, 2003, Volume: 88, Issue:4

    Topics: Animals; Cardiomegaly; DNA, Antisense; Endothelium, Vascular; Enzyme Inhibitors; Genetic Therapy; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Retroviridae

2003
Imidapril improves L-NAME-exacerbated nephrosclerosis with TGF-beta 1 inhibition in spontaneously hypertensive rats.
    Journal of hypertension, 2004, Volume: 22, Issue:7

    Topics: Animals; Antihypertensive Agents; Aorta; Cardiomegaly; Caspase 3; Caspases; Enzyme Inhibitors; Hypertension, Renal; Imidazolidines; Kidney; Male; Nephrosclerosis; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
    Circulation, 2004, Aug-10, Volume: 110, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Celiprolol; Cells, Cultured; Disease Progression; Drug Evaluation, Preclinical; Enzyme Induction; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertrophy; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenylephrine; Pressure; Rats; RNA, Messenger; Transcription, Genetic; Vasodilator Agents

2004
Upregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in rats.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:2

    Topics: Adrenomedullin; Animals; Blood Pressure; Body Weight; Cardiomegaly; Drug Administration Schedule; Enzyme Inhibitors; Heart Ventricles; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Peptides; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Up-Regulation

2006
Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats.
    Life sciences, 2005, Nov-26, Volume: 78, Issue:2

    Topics: Algorithms; Animals; Arteries; Body Weight; Cardiomegaly; Cell Count; Collagen; Cyclic GMP; Electrocardiography; Enzyme Inhibitors; Hemodynamics; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Ventricular Function, Left

2005
Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat.
    Kidney & blood pressure research, 2005, Volume: 28, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartate Aminotransferases; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Creatinine; Enzyme Inhibitors; Glutathione; Heart Rate; Hypertension, Renal; L-Lactate Dehydrogenase; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar

2005
Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
    Circulation, 2005, Nov-08, Volume: 112, Issue:19

    Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; rho-Associated Kinases; Vascular Diseases

2005
Protective effects of BAY 41-2272 (sGC stimulator) on hypertension, heart, and cardiomyocyte hypertrophy induced by chronic L-NAME treatment in rats.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Fibrosis; Guanylate Cyclase; Heart Rate; Hypertension; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrazoles; Pyridines; Rats; Rats, Wistar

2006
Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Heart Atria; Heart Rate; Hydralazine; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Tetrazoles; Thrombomodulin

2006
Apoptosis signal-regulating kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:3

    Topics: Animals; Apoptosis; Blood Pressure; Cardiomegaly; Chemokine CCL2; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Macrophages; MAP Kinase Kinase Kinase 5; Mice; Mice, Knockout; Muscle Cells; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrogen Oxides; Superoxides; Transforming Growth Factor beta; Ventricular Remodeling

2007
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Angiogenic Proteins; Animals; Cardiomegaly; Cells, Cultured; Echocardiography; Endothelial Cells; Enzyme Inhibitors; Heart; Hemodynamics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Transgenes

2007
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Cardiomegaly; Cardiomyopathy, Restrictive; Coronary Vessels; Echocardiography, Doppler; Enzyme Inhibitors; In Situ Nick-End Labeling; Ligation; Male; Mice; Mice, Inbred ICR; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperazines; Pulmonary Edema; Purines; Sildenafil Citrate; Sulfones; Survival Analysis; Vasodilator Agents; Ventricular Function, Left; Ventricular Remodeling

2008
Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:7

    Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Eye Proteins; Fibrosis; Gelatinases; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Growth Factors; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Serpins; Thoracic Arteries; Tumor Suppressor Protein p53

2008
Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1

    Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Data Interpretation, Statistical; Enzyme Inhibitors; Fibrosis; Heart; Heart Rate; Histological Techniques; Hydralazine; Hypertension; Male; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY

1995
Role of kinins and nitric oxide in the antihypertrophic effect of ramipril.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2

    Topics: Amino Acid Oxidoreductases; Animals; Aortic Coarctation; Arginine; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Heart Ventricles; Hypertension; Kinins; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Ramipril; Rats

1994
Ramipril prevents the detrimental sequels of chronic NO synthase inhibition in rats: hypertension, cardiac hypertrophy and renal insufficiency.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:6

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiomegaly; Cyclic GMP; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ramipril; Rats; Rats, Wistar; Renal Insufficiency; Ventricular Fibrillation

1994
Effect of an angiotensin II receptor antagonist, TCV-116, on cardiac hypertrophy and coronary circulation in spontaneously hypertensive rats.
    Blood pressure. Supplement, 1994, Volume: 5

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prodrugs; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vascular Resistance

1994
Decreased cardiac baroreflex sensitivity is not due to cardiac hypertrophy in NG-nitro-L-arginine methyl ester-induced hypertension.
    Journal of hypertension, 1994, Volume: 12, Issue:7

    Topics: Animals; Arginine; Baroreflex; Blood Pressure; Cardiomegaly; Heart; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reference Values

1994
Hypertension without cardiac hypertrophy does not induce a cardiac baroreflex deficit.
    Journal of hypertension, 1996, Volume: 14, Issue:10

    Topics: Animals; Baroreflex; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar

1996
Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 1996, Volume: 14, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiomegaly; Cilazapril; Desoxycorticosterone; Endothelin-1; Hypertension; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Size; Rats; Rats, Sprague-Dawley; Renin

1996
Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats.
    The Journal of clinical investigation, 1997, Jan-15, Volume: 99, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Coronary Vessels; Enzyme Inhibitors; Fibrosis; Immunohistochemistry; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Tissue Distribution

1997
Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:6

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bradykinin; Cardiomegaly; Coronary Vessels; Fibrosis; Heart; Heart Rate; Imidazoles; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Olmesartan Medoxomil; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Thiazepines

1997
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Actins; Aldosterone; Animals; Aorta, Thoracic; Carbachol; Cardiomegaly; Cell Cycle; DNA; Heart; Hypertension; In Vitro Techniques; Isometric Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Polyploidy; Rats; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Transcription, Genetic

1998
Role of NO and angiotensin II in the early development of endothelial functions impairment and cardiac hypertrophy in deoxycorticosterone acetate-salt hypertension.
    Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Desoxycorticosterone; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Sodium Chloride; Splanchnic Circulation

1998
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Cell Nucleus; Diastole; DNA; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Indoles; Losartan; Lymphocytes; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Perindopril; Rats; Rats, Inbred SHR; Systole; Telemetry; Time Factors

1999
Aortic connexin43 is decreased during hypertension induced by inhibition of nitric oxide synthase.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:7

    Topics: Animals; Aorta; Cardiomegaly; Carotid Arteries; Connexin 43; Enzyme Inhibitors; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylation; Rats; Rats, Inbred WKY

1999
Chronic N(G)-nitro-L-arginine methyl ester-induced hypertension : novel molecular adaptation to systolic load in absence of hypertrophy.
    Circulation, 2000, Feb-01, Volume: 101, Issue:4

    Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Calcium; Cardiomegaly; Cyclic GMP; Hypertension; Major Histocompatibility Complex; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Systole; Transcription, Genetic

2000
Development of cardiomyocyte hypotrophy in rats under prolonged treatment with a low dose of a nitric oxide synthesis inhibitor.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Animals; Blood Pressure; Body Weight; Brain; Cardiomegaly; Enzyme Inhibitors; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Wistar

2000
Differential effects of imidapril and candesartan cilexetil on plasminogen activator inhibitor-1 expression induced by prolonged inhibition of nitric oxide synthesis in rat hearts.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6

    Topics: Actins; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Gene Expression Regulation; Heart; Imidazoles; Imidazolidines; Immunohistochemistry; Male; Muscle, Skeletal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles

2000
Cardiovascular effects of chronic nitric oxide synthase inhibition in genetically hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:7

    Topics: Aging; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hindlimb; Hypertension; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow

2000
Quantitative study of myocardial microcirculation in arterial hypertension due to progressive inhibition of NO synthesis.
    Arquivos brasileiros de cardiologia, 1999, Volume: 73, Issue:5

    Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Enzyme Inhibitors; Hypertension; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats; Rats, Wistar; Time Factors

1999
Enhanced expression of Gi proteins in non-hypertrophic hearts from rats with hypertension-induced by L-NAME treatment.
    Journal of hypertension, 2000, Volume: 18, Issue:8

    Topics: Adenylyl Cyclases; Animals; Blotting, Northern; Blotting, Western; Cardiomegaly; Cholera Toxin; Densitometry; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stimulation, Chemical; Subcellular Fractions

2000
Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats.
    Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hydralazine; Imidazoles; Imidazolidines; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases; Sirolimus; Ventricular Remodeling

2000
Compensated heart failure predisposes to outer medullary tubular injury: studies in rats.
    Kidney international, 2001, Volume: 60, Issue:2

    Topics: Acute Kidney Injury; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Hypoxia; Indomethacin; Kidney Medulla; Kidney Tubular Necrosis, Acute; Loop of Henle; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction; Vasodilation

2001
Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Coronary Vessels; Enalapril; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Imidazoles; Losartan; Male; Mitogen-Activated Protein Kinases; Myocardium; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Olmesartan Medoxomil; Organ Size; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ribosomal Protein S6 Kinases; Tetrazoles; Thiazepines

2001
Stereology of cardiac hypertrophy induced by NO blockade in rats treated with enalapril and verapamil.
    Analytical and quantitative cytology and histology, 2001, Volume: 23, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Enalapril; Male; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Verapamil

2001
The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload.
    Molecular and cellular biochemistry, 2002, Volume: 229, Issue:1-2

    Topics: Animals; Apoptosis; Body Weight; Cardiomegaly; Disease Models, Animal; DNA Fragmentation; Enzyme Inhibitors; Genetic Variation; Heart; Hemodynamics; Hypertension; Insulin-Like Growth Factor I; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Elongation Factor 2; Rats; Rats, Wistar

2002
Heart remodeling in the hereditary hypertriglyceridemic rat: effect of captopril and nitric oxide deficiency.
    Annals of the New York Academy of Sciences, 2002, Volume: 967

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Cardiomegaly; Enzyme Inhibitors; Hypertriglyceridemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats

2002