ng-nitroarginine methyl ester has been researched along with Cardiomegaly in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (20.83) | 18.2507 |
| 2000's | 31 (43.06) | 29.6817 |
| 2010's | 24 (33.33) | 24.3611 |
| 2020's | 2 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Balkan, W; Cai, R; Dulce, RA; Hare, JM; Kanashiro-Takeuchi, RM; Kazmierczak, K; Schally, AV; Sha, W; Takeuchi, LM | 1 |
| Huang, S; Jia, Z; Niu, Y; Shi, W; Wang, S; Yu, J; Zhang, A; Zhang, Y; Zhou, W | 1 |
| Abolarinwa, BA; Achile, CJ; Kim, IK; Olaniyi, KS; Olatunji, LA; Usman, TO | 1 |
| Abo-Elmatty, DM; El-Baz, AA; Ibrahim, A; Mosaad, SM; Moustafa, YM; Zaitone, SA | 1 |
| Hein, TW; Kuo, L; Lu, G; Ren, Y; Tsai, SH; Xu, X | 1 |
| Almeida, JF; Alves, GM; Castro, CH; Colugnati, DB; Ferreira, AJ; Macedo, LM; Mendes, EP; Porto, JE; Santos, RA; Sobrinho, DB; Souza, ÁP; Vêncio, EF | 1 |
| Boe, AE; Eren, M; Ichimura, A; Kamide, CE; McAnally, D; Miyata, T; Murphy, SB; Smith, LH; Terry, D; Vaughan, DE | 1 |
| Hambly, BD; Lai, YN; McLachlan, CS; Ocsan, RJ; Prabhu, KV | 1 |
| Jia, Z; Li, J; Liu, J; Qi, Z; Tang, X; Tian, W; Wu, P; Yang, L; Zhang, J; Zhu, M | 1 |
| Coelho-Filho, OR; Jerosch-Herold, M; Kwong, R; Mitchell, R; Moreno, H; Neilan, TG; Shah, RV | 1 |
| Cacanyiova, S; Drobna, M; Kristek, F | 1 |
| Iwao, H; Izumi, Y; Kawaguchi, H; Miura, K; Nakamura, Y; Okamura, T; Osada-Oka, M; Shiota, M; Tanimoto, A; Tawa, M; Yamaguchi, T; Yamazaki, T; Yoshiyama, M | 1 |
| Lira, VA | 1 |
| Li, J; Liu, J; Lu, P; Qi, Z; Ren, J; Tian, W; Yang, L; Zhu, M | 1 |
| Engle, SK; Watson, DE | 1 |
| Cao, TN; Cordero-Reyes, AM; Gupte, AA; Hamilton, DJ; Li, S; Smith, JA; Torre-Amione, G; Vedula, I; Youker, KA; Zhang, A | 1 |
| Aslan, M; Olgar, Y; Ozdemir, S; Ozturk, N | 1 |
| Coffman, TM; Ellison, J; Francois, H; Makhanova, N; Mao, L; Rockman, HA; Ruiz, P | 1 |
| Bonney, W; Cheema, FH; Gonzalez, AM; Homma, S; Kinnear, C; Liao, JK; Mahmut, N; Martens, TP; Mital, S; Osorio, JC | 1 |
| McLemore, GR; Ryan, MJ; Stec, DE; Storm, MV; Vera, T | 1 |
| Adler, GK; Coutinho, P; Guo, C; Lapointe, N; Loutraris, P; Pojoga, LH; Ricchiuti, V; Romero, JR; Stone, JR; Williams, GH; Yao, TM | 1 |
| Berger, S; Duan, SZ; Frieler, RA; Ivaschenko, CY; Lumeng, CN; Mortensen, RM; Schütz, G; Usher, MG | 1 |
| Bell, D; Campbell, M; Cosby, SL; Earle, JA; McDermott, BJ; Wang, X | 1 |
| Baumann, M; Eissler, R; Heemann, U; Kühne, L; Lahmer, T; Lutz, J; Rusai, K; Schmaderer, C; Sollinger, D; Witzke, O | 1 |
| Buckley, MM; Johns, EJ | 1 |
| Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I | 1 |
| Fantinelli, JC; González Arbeláez, LF; Mosca, SM; Pérez Núñez, IA; Schinella, GR | 1 |
| Dinda, AK; Maulik, SK; Prabhakar, P; Seth, S | 1 |
| Al Kaabba, A; Khatib, S; Mohammad, M; Siam, A; Zeidan, A | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sanada, S; Takashima, S | 2 |
| Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Minamino, T; Node, K; Ogita, H; Sanada, S; Takashima, S | 1 |
| Beck, CR; Katovich, MJ; Raizada, MK; Reaves, PY; Wang, HW | 1 |
| Ishimitu, T; Matsuoka, H; Ono, H; Ono, Y; Saitoh, M | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Liao, Y; Minamino, T; Ogai, A; Sanada, S; Shintani, Y; Takashima, S; Tomoike, H | 1 |
| Wang, YX | 1 |
| Bell, D; Kelso, EJ; Lamont, VM; McDermott, BJ; McHenry, EM; Nicholls, DP; Rush, LM; Zhao, YY | 1 |
| Chang, HR; Chen, HI; Hsu, YH; Hu, CT; Liu, CJ | 1 |
| Al-Shabanah, O; Khattab, MM; Mostafa, A | 1 |
| Kim, HH; Liao, JK; Noma, K; Oyama, N; Rikitake, Y; Satoh, M; Wang, CY | 1 |
| Antunes, E; Araujo, EG; De Nucci, G; Faro, R; Guaraldo, AM; Zanfolin, M | 1 |
| Kim, J; Kitakaze, M; Minamino, T; Mochizuki, N; Myoishi, M; Okada, K; Okazaki, H; Takashima, S; Tsukamoto, O; Wakeno, M | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Carmeliet, P; Chorianopoulos, E; Elfenbein, A; Eriksson, U; Fu, Q; Hall, AE; Moodie, KL; Moons, L; Palac, RT; Roncal, C; Simons, M; Tirziu, D; Tjwa, M; Zhuang, ZW | 1 |
| Abbate, A; Brown, WR; Das, A; Hoke, NN; Houser, JE; Kukreja, RC; Mudrick, CA; Prabhakar, S; Qureshi, IZ; Roy, SK; Salloum, FN | 1 |
| Hou, Y; Matsuo, O; Okada, K; Okamoto, C; Ueshima, S | 1 |
| Egashira, K; Kadokami, T; Numaguchi, K; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A | 1 |
| Carretero, OA; Rhaleb, NE; Scicli, AG; Yang, XP | 1 |
| Grötsch, H; Hropot, M; Klaus, E; Langer, KH; Linz, W; Schölkens, BA; Wiemer, G | 1 |
| Fujita, H; Itoh, H; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K; Tanaka, M; Uchida, A | 1 |
| Lantelme, P; Lo, M; Sassard, J | 1 |
| Adams, MA; Banting, JD; Wiseman, SL | 1 |
| Li, JS; Schiffrin, EL; Sventek, P | 1 |
| Egashira, K; Numaguchi, K; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A; Tomita, H; Tsutsui, H; Usui, M | 1 |
| Egashira, K; Kitabatake, A; Okamoto, H; Shimokawa, H; Sueishi, K; Takemoto, M; Takeshita, A; Tomita, H; Usui, M | 1 |
| Anderson, NH; Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McPhaden, A; Reid, JL | 1 |
| Brosnan, MJ; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M; McPhaden, AR; Morton, JJ; Reid, JL | 1 |
| Cardinal, R; de Champlain, J; K-Laflamme, A; Oster, L | 1 |
| Anderson, NH; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; Morton, JJ; Reid, JL; Schork, NJ | 1 |
| Brunner, HR; Formenton, A; Haefliger, JA; Hayoz, D; Meda, P; Nicod, P; Wiesel, P; Zanchi, A | 1 |
| Bartunek, J; Douglas, PS; Katz, SE; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO | 1 |
| Antunes, E; Cintra, KA; De Luca, IM; De Nucci, G; de Oliveira, CF; Teixeira, SA | 1 |
| Egashira, K; Katoh, M; Mitsui, T; Narita, H; Takeshita, A | 1 |
| Laverty, R; Ledingham, JM; Orange, SJ | 1 |
| Mandarim-De-Lacerda, CA; Pereira, LM | 2 |
| Anand-Srivastava, MB; Di Fusco, F | 1 |
| Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Ogai, A; Papst, PJ; Sakata, Y; Terada, N; Ueda, Y | 1 |
| Abassi, Z; Brezis, M; Goldfarb, M; Heyman, SN; Rosen, S; Shina, A | 1 |
| Asakura, M; Asanuma, H; Fukushima, T; Hori, M; Kitakaze, M; Kuzuya, T; Liao, Y; Minamino, T; Node, K; Ogai, A; Ogita, H; Sakata, Y; Sanada, S; Takashima, S; Yamada, J | 1 |
| Holtz, J; Jäger, D; Müller, SP; Müller-Werdan, U; Pönicke, K; Werdan, K | 1 |
| Babal, P; Bernatova, I; Hulin, I; Luptak, I; Matuskova, J; Pechanova, O; Simko, F | 1 |
2 review(s) available for ng-nitroarginine methyl ester and Cardiomegaly
| Article | Year |
|---|---|
Cardiovascular functional phenotypes and pharmacological responses in apolipoprotein E deficient mice.
Topics: Angiotensin II; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Cardiac Output, High; Cardiomegaly; Cardiovascular System; Enzyme Inhibitors; Estradiol; Hypercholesterolemia; Hyperglycemia; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Phenotype; Simvastatin | 2005 |
Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Susceptibility; Humans; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1997 |
70 other study(ies) available for ng-nitroarginine methyl ester and Cardiomegaly
| Article | Year |
|---|---|
Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Growth Hormone-Releasing Hormone; Heart Failure; Inflammation; Mice; NG-Nitroarginine Methyl Ester; Stroke Volume; Vascular Endothelial Growth Factor A; Ventricular Function, Left | 2023 |
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Electrolytes; Endothelial Cells; Glycine; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Kidney Glomerulus; Male; Mice; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proteinuria; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Urine; Vascular Remodeling | 2021 |
Combined oral contraceptive and nitric oxide synthesis inhibition synergistically causes cardiac hypertrophy and exacerbates insulin resistance in female rats.
Topics: Animals; Blood Pressure; C-Reactive Protein; Cardiomegaly; Contraceptives, Oral, Combined; Estradiol; Ethinyl Estradiol; Female; Insulin Resistance; Levonorgestrel; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Rats, Wistar; Uric Acid | 2017 |
Celecoxib aggravates cardiac apoptosis in L-NAME-induced pressure overload model in rats: Immunohistochemical determination of cardiac caspase-3, Mcl-1, Bax and Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Caspase 3; Celecoxib; Creatine Kinase, MB Form; Disease Models, Animal; DNA Fragmentation; L-Lactate Dehydrogenase; Male; Myeloid Cell Leukemia Sequence 1 Protein; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2017 |
Enhanced endothelin-1/Rho-kinase signalling and coronary microvascular dysfunction in hypertensive myocardial hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arterioles; Cardiomegaly; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; rho-Associated Kinases; Signal Transduction; Vasoconstriction; Vasodilator Agents | 2017 |
Angiotensin II type 1 receptor blockade restores angiotensin-(1-7)-induced coronary vasodilation in hypertrophic rat hearts.
Topics: Angiotensin I; Animals; Cardiomegaly; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Vasodilation | 2013 |
Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence.
Topics: Animals; Aorta; Blood Pressure; Cardiomegaly; Cellular Senescence; Drug Interactions; Enzyme Inhibitors; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; para-Aminobenzoates; Piperazines; Rats; Rats, Wistar; Serpin E2; Structure-Activity Relationship; Telomere | 2013 |
Chronic NG-nitro-l-arginine methyl ester (L-NAME) administration in C57BL/6J mice induces a sustained decrease in c-kit positive cells during development of cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Proto-Oncogene Proteins c-kit | 2013 |
Exercise protects against chronic β-adrenergic remodeling of the heart by activation of endothelial nitric oxide synthase.
Topics: Animals; Cardiomegaly; Fibrosis; Heart; Hemodynamics; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Physical Conditioning, Animal; Proto-Oncogene Proteins c-akt; Receptors, Adrenergic, beta; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transcriptional Activation | 2014 |
Cardiac magnetic resonance assessment of interstitial myocardial fibrosis and cardiomyocyte hypertrophy in hypertensive mice treated with spironolactone.
Topics: Animals; Cardiac Imaging Techniques; Cardiomegaly; Fibrosis; Heart; Hypertension; Magnetic Resonance Imaging; Mice; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Receptors, Mineralocorticoid; Spironolactone; Stroke Volume | 2014 |
Different effects of 7-nitroindazole and L-NAME administered both individually and together on the cardiovascular system of the rat.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Carotid Arteries; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats, Inbred SHR; Rats, Wistar; Vascular Remodeling; Vasodilation; Ventricular Remodeling | 2015 |
Noninvasive metabolic syndrome model using an extremely small minipig, the microminipig.
Topics: Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Cholesterol, Dietary; Coronary Vessels; Diet, High-Fat; Disease Models, Animal; Drug Discovery; Endothelium, Vascular; Lipoproteins, LDL; Male; Metabolic Syndrome; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Swine; Swine, Miniature | 2014 |
Exercise-induced cardioprotection: more to k‘NO’w.
Topics: Animals; Blood Pressure; Cardiomegaly; Female; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase | 2015 |
Nitric oxide synthase inhibition abolishes exercise-mediated protection against isoproterenol-induced cardiac hypertrophy in female mice.
Topics: Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Echocardiography; Enzyme Inhibitors; Female; Fibrosis; Isoproterenol; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Physical Conditioning, Animal; Real-Time Polymerase Chain Reaction; Up-Regulation | 2015 |
Natriuretic Peptides as Cardiovascular Safety Biomarkers in Rats: Comparison With Blood Pressure, Heart Rate, and Heart Weight.
Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomegaly; Heart Rate; Indoles; Male; Minoxidil; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Size; Peptide Fragments; Prostaglandins F, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Sunitinib; Thyroxine | 2016 |
Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; DNA, Mitochondrial; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Gene Expression; Heart; Heart Failure; Hydrogen Peroxide; Mice; Mitochondria, Heart; Myocardium; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Protein Precursors; Pyruvate Dehydrogenase Complex; Reverse Transcriptase Polymerase Chain Reaction; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Vasoconstrictor Agents | 2016 |
Effects of magnesium supplementation on electrophysiological remodeling of cardiac myocytes in L-NAME induced hypertensive rats.
Topics: Animals; Atrial Remodeling; Calcium; Cardiomegaly; Dietary Supplements; Heart Ventricles; Hypertension; Magnesium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats | 2016 |
A role for the thromboxane receptor in L-NAME hypertension.
Topics: Albuminuria; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Drinking; Eating; Enzyme Inhibitors; Hypertension, Renal; Isoprostanes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Thromboxane A2, Prostaglandin H2; Renin-Angiotensin System; Sodium, Dietary; Thromboxane B2 | 2008 |
Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor.
Topics: Animals; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Signal Transduction; Simvastatin; Stroke Volume; Ultrasonography | 2008 |
Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Vascular Resistance; Vasoconstriction | 2009 |
Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Caveolin 1; Endothelial Cells; Male; Mice; Mice, Knockout; Molecular Sequence Data; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Signal Transduction | 2010 |
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.
Topics: Aldosterone; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Fibrosis; Heart; Hypertension; Hypertrophy; Interleukin-4; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; NG-Nitroarginine Methyl Ester; Receptors, Glucocorticoid; Receptors, Mineralocorticoid | 2010 |
Adrenomedullin gene delivery is cardio-protective in a model of chronic nitric oxide deficiency combining pressure overload, oxidative stress and cardiomyocyte hypertrophy.
Topics: Adrenomedullin; Animals; Atrial Natriuretic Factor; Cardiomegaly; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Humans; Myocytes, Cardiac; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pressure; Rats; Superoxide Dismutase | 2010 |
Hypertension augments cardiac Toll-like receptor 4 expression and activity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Chemokine CCL2; Heparitin Sulfate; Hypertension; Interleukin-6; Myocardium; NG-Nitroarginine Methyl Ester; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Impact of L-NAME on the cardiopulmonary reflex in cardiac hypertrophy.
Topics: Animals; Baroreflex; Blood Pressure; Blood Volume; Caffeine; Cardiomegaly; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Heart Rate; Isoproterenol; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Sympathetic Nervous System; Thyroxine; Urodynamics | 2011 |
Role of angiotensin-converting enzyme 2 in cardiac hypertrophy induced by nitric oxide synthase inhibition.
Topics: Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger | 2011 |
Participation of mitochondrial permeability transition pore in the effects of ischemic preconditioning in hypertrophied hearts: role of NO and mitoKATP.
Topics: Animals; Cardiomegaly; Ischemic Preconditioning, Myocardial; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Treatment Outcome | 2013 |
Genistein prevents isoproterenol-induced cardiac hypertrophy in rats.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genistein; Glutathione; Guanidines; Hydroxyproline; Isoproterenol; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
The ability of phosphodiesterase-5 inhibitors sildenafil and ordonafil to reverse L-NAME induced cardiac hypertrophy in the rabbit: possible role of calcineurin and p38.
Topics: Animals; Calcineurin; Cardiomegaly; Cell Size; Female; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rabbits; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones | 2012 |
Opening of the adenosine triphosphate-sensitive potassium channel attenuates cardiac remodeling induced by long-term inhibition of nitric oxide synthesis: role of 70-kDa S6 kinase and extracellular signal-regulated kinase.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Body Weight; Cardiomegaly; Glyburide; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases | 2002 |
[Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Chromans; Hydralazine; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channels; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Ventricular Remodeling | 2003 |
Long-acting Ca2+ blockers prevent myocardial remodeling induced by chronic NO inhibition in rats.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Kinetics; Male; Mitogen-Activated Protein Kinases; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases, 70-kDa | 2003 |
Endothelial-independent prevention of high blood pressure in L-NAME-treated rats by angiotensin II type I receptor antisense gene therapy.
Topics: Animals; Cardiomegaly; DNA, Antisense; Endothelium, Vascular; Enzyme Inhibitors; Genetic Therapy; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Retroviridae | 2003 |
Imidapril improves L-NAME-exacerbated nephrosclerosis with TGF-beta 1 inhibition in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Aorta; Cardiomegaly; Caspase 3; Caspases; Enzyme Inhibitors; Hypertension, Renal; Imidazolidines; Kidney; Male; Nephrosclerosis; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Celiprolol; Cells, Cultured; Disease Progression; Drug Evaluation, Preclinical; Enzyme Induction; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertrophy; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenylephrine; Pressure; Rats; RNA, Messenger; Transcription, Genetic; Vasodilator Agents | 2004 |
Upregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in rats.
Topics: Adrenomedullin; Animals; Blood Pressure; Body Weight; Cardiomegaly; Drug Administration Schedule; Enzyme Inhibitors; Heart Ventricles; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Peptides; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Up-Regulation | 2006 |
Ventricular hypertrophy and arterial hemodynamics following deprivation of nitric oxide in rats.
Topics: Algorithms; Animals; Arteries; Body Weight; Cardiomegaly; Cell Count; Collagen; Cyclic GMP; Electrocardiography; Enzyme Inhibitors; Hemodynamics; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2005 |
Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartate Aminotransferases; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Creatinine; Enzyme Inhibitors; Glutathione; Heart Rate; Hypertension, Renal; L-Lactate Dehydrogenase; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar | 2005 |
Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; rho-Associated Kinases; Vascular Diseases | 2005 |
Protective effects of BAY 41-2272 (sGC stimulator) on hypertension, heart, and cardiomyocyte hypertrophy induced by chronic L-NAME treatment in rats.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Fibrosis; Guanylate Cyclase; Heart Rate; Hypertension; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrazoles; Pyridines; Rats; Rats, Wistar | 2006 |
Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Heart Atria; Heart Rate; Hydralazine; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Tetrazoles; Thrombomodulin | 2006 |
Apoptosis signal-regulating kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency.
Topics: Animals; Apoptosis; Blood Pressure; Cardiomegaly; Chemokine CCL2; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Macrophages; MAP Kinase Kinase Kinase 5; Mice; Mice, Knockout; Muscle Cells; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrogen Oxides; Superoxides; Transforming Growth Factor beta; Ventricular Remodeling | 2007 |
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice.
Topics: Angiogenic Proteins; Animals; Cardiomegaly; Cells, Cultured; Echocardiography; Endothelial Cells; Enzyme Inhibitors; Heart; Hemodynamics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Transgenes | 2007 |
Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice.
Topics: Animals; Apoptosis; Blotting, Western; Cardiomegaly; Cardiomyopathy, Restrictive; Coronary Vessels; Echocardiography, Doppler; Enzyme Inhibitors; In Situ Nick-End Labeling; Ligation; Male; Mice; Mice, Inbred ICR; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperazines; Pulmonary Edema; Purines; Sildenafil Citrate; Sulfones; Survival Analysis; Vasodilator Agents; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Eye Proteins; Fibrosis; Gelatinases; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Growth Factors; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Serpins; Thoracic Arteries; Tumor Suppressor Protein p53 | 2008 |
Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats.
Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Data Interpretation, Statistical; Enzyme Inhibitors; Fibrosis; Heart; Heart Rate; Histological Techniques; Hydralazine; Hypertension; Male; Microcirculation; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY | 1995 |
Role of kinins and nitric oxide in the antihypertrophic effect of ramipril.
Topics: Amino Acid Oxidoreductases; Animals; Aortic Coarctation; Arginine; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Heart Ventricles; Hypertension; Kinins; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Ramipril; Rats | 1994 |
Ramipril prevents the detrimental sequels of chronic NO synthase inhibition in rats: hypertension, cardiac hypertrophy and renal insufficiency.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiomegaly; Cyclic GMP; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ramipril; Rats; Rats, Wistar; Renal Insufficiency; Ventricular Fibrillation | 1994 |
Effect of an angiotensin II receptor antagonist, TCV-116, on cardiac hypertrophy and coronary circulation in spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Vessels; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prodrugs; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vascular Resistance | 1994 |
Decreased cardiac baroreflex sensitivity is not due to cardiac hypertrophy in NG-nitro-L-arginine methyl ester-induced hypertension.
Topics: Animals; Arginine; Baroreflex; Blood Pressure; Cardiomegaly; Heart; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reference Values | 1994 |
Hypertension without cardiac hypertrophy does not induce a cardiac baroreflex deficit.
Topics: Animals; Baroreflex; Blood Pressure; Cardiomegaly; Heart Rate; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 1996 |
Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiomegaly; Cilazapril; Desoxycorticosterone; Endothelin-1; Hypertension; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Size; Rats; Rats, Sprague-Dawley; Renin | 1996 |
Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Coronary Vessels; Enzyme Inhibitors; Fibrosis; Immunohistochemistry; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Tissue Distribution | 1997 |
Chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade: effects on cardiovascular remodeling in rats induced by the long-term blockade of nitric oxide synthesis.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bradykinin; Cardiomegaly; Coronary Vessels; Fibrosis; Heart; Heart Rate; Imidazoles; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Olmesartan Medoxomil; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Thiazepines | 1997 |
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
Topics: Actins; Aldosterone; Animals; Aorta, Thoracic; Carbachol; Cardiomegaly; Cell Cycle; DNA; Heart; Hypertension; In Vitro Techniques; Isometric Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Polyploidy; Rats; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Transcription, Genetic | 1998 |
Role of NO and angiotensin II in the early development of endothelial functions impairment and cardiac hypertrophy in deoxycorticosterone acetate-salt hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Desoxycorticosterone; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Sodium Chloride; Splanchnic Circulation | 1998 |
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Cell Nucleus; Diastole; DNA; Female; Heart Rate; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Indoles; Losartan; Lymphocytes; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Perindopril; Rats; Rats, Inbred SHR; Systole; Telemetry; Time Factors | 1999 |
Aortic connexin43 is decreased during hypertension induced by inhibition of nitric oxide synthase.
Topics: Animals; Aorta; Cardiomegaly; Carotid Arteries; Connexin 43; Enzyme Inhibitors; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylation; Rats; Rats, Inbred WKY | 1999 |
Chronic N(G)-nitro-L-arginine methyl ester-induced hypertension : novel molecular adaptation to systolic load in absence of hypertrophy.
Topics: Animals; Aortic Valve Stenosis; Blood Pressure; Calcium; Cardiomegaly; Cyclic GMP; Hypertension; Major Histocompatibility Complex; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Systole; Transcription, Genetic | 2000 |
Development of cardiomyocyte hypotrophy in rats under prolonged treatment with a low dose of a nitric oxide synthesis inhibitor.
Topics: Animals; Blood Pressure; Body Weight; Brain; Cardiomegaly; Enzyme Inhibitors; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Wistar | 2000 |
Differential effects of imidapril and candesartan cilexetil on plasminogen activator inhibitor-1 expression induced by prolonged inhibition of nitric oxide synthesis in rat hearts.
Topics: Actins; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Gene Expression Regulation; Heart; Imidazoles; Imidazolidines; Immunohistochemistry; Male; Muscle, Skeletal; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles | 2000 |
Cardiovascular effects of chronic nitric oxide synthase inhibition in genetically hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hindlimb; Hypertension; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow | 2000 |
Quantitative study of myocardial microcirculation in arterial hypertension due to progressive inhibition of NO synthesis.
Topics: Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Enzyme Inhibitors; Hypertension; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats; Rats, Wistar; Time Factors | 1999 |
Enhanced expression of Gi proteins in non-hypertrophic hearts from rats with hypertension-induced by L-NAME treatment.
Topics: Adenylyl Cyclases; Animals; Blotting, Northern; Blotting, Western; Cardiomegaly; Cholera Toxin; Densitometry; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stimulation, Chemical; Subcellular Fractions | 2000 |
Inhibition of nitric oxide synthesis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Coronary Vessels; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hydralazine; Imidazoles; Imidazolidines; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred WKY; Ribosomal Protein S6 Kinases; Sirolimus; Ventricular Remodeling | 2000 |
Compensated heart failure predisposes to outer medullary tubular injury: studies in rats.
Topics: Acute Kidney Injury; Animals; Cardiomegaly; Cardiovascular Agents; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Hypoxia; Indomethacin; Kidney Medulla; Kidney Tubular Necrosis, Acute; Loop of Henle; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction; Vasodilation | 2001 |
Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Coronary Vessels; Enalapril; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Imidazoles; Losartan; Male; Mitogen-Activated Protein Kinases; Myocardium; Neutrophil Infiltration; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Olmesartan Medoxomil; Organ Size; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ribosomal Protein S6 Kinases; Tetrazoles; Thiazepines | 2001 |
Stereology of cardiac hypertrophy induced by NO blockade in rats treated with enalapril and verapamil.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Enalapril; Male; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Verapamil | 2001 |
The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload.
Topics: Animals; Apoptosis; Body Weight; Cardiomegaly; Disease Models, Animal; DNA Fragmentation; Enzyme Inhibitors; Genetic Variation; Heart; Hemodynamics; Hypertension; Insulin-Like Growth Factor I; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Elongation Factor 2; Rats; Rats, Wistar | 2002 |
Heart remodeling in the hereditary hypertriglyceridemic rat: effect of captopril and nitric oxide deficiency.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Cardiomegaly; Enzyme Inhibitors; Hypertriglyceridemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats | 2002 |