ng-nitroarginine methyl ester has been researched along with Aging in 178 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 50 (28.09) | 18.2507 |
| 2000's | 81 (45.51) | 29.6817 |
| 2010's | 46 (25.84) | 24.3611 |
| 2020's | 1 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Csiszar, A; Tarantini, S; Ungvari, A; Ungvari, Z; Yabluchanskiy, A | 1 |
| Bellini, C; Caulk, AW; Ferruzzi, J; Humphrey, JD; Murtada, SI; Spronck, B | 1 |
| Chertok, AG; Chertok, VM; Kotsyuba, AE | 1 |
| Smith, FG; Vinturache, AE | 1 |
| Ashikari, A; Kimura, R; Miyazato, M; Oshiro, T; Saito, S | 1 |
| Maslyukov, AP; Maslyukov, PM; Moiseev, KY; Verbovetskaya, AI | 1 |
| Bourque, SL; Davidge, ST; Gragasin, FS | 1 |
| Dantas, AP; Garabito, M; Hermenegildo, C; Medina, P; Mompeón, A; Novella, S; Segarra, G; Vidal-Gómez, X | 1 |
| Donato, AJ; Durrant, JR; Folian, BJ; Lesniewski, LA; Nowlan, MJ; Seals, DR; Zigler, ML | 1 |
| Abbas, AM; Abdel-Malek, H; Omar, NM; Suddek, GM | 1 |
| Carter, M; Fujii, N; Kenny, GP; Stapleton, JM | 1 |
| Hasegawa, Y; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Ma, M; Maeda, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H | 1 |
| Gao, YZ; Morgan, KG; Saphirstein, RJ; Suki, B; Yamin, R | 1 |
| Azma, T; Hatakeyama, N; Kawahito, S; Kinoshita, H; Kitahata, H; Mita, N; Nakaya, Y; Sakai, Y; Takaishi, K | 1 |
| Cruz, M; García-Macedo, R; Gómez-Zamudio, JH; Ibarra-Barajas, M; Kumate, J; Lázaro-Suárez, M | 1 |
| Chang, F; Flavahan, NA; Flavahan, S | 1 |
| Breevoort, SR; Donato, AJ; Hazra, S; Henson, GD; Ives, SJ; Lesniewski, LA; Morgan, RG; Richardson, RS | 1 |
| Kim, N; Kim, SK; Kim, YS; Kwon, YH; Lee, DH; Lee, HS; Lee, SM; Nam, RH; Park, JH | 1 |
| Ashpole, N; Csiszar, A; Fulop, GA; Gautam, T; Giles, CB; Sonntag, WE; Springo, Z; Tarantini, S; Ungvari, Z; Valcarcel-Ares, NM; Wren, JD; Yabluchanskiy, A | 1 |
| Chakraborti, A; Gulati, K; Ray, A | 1 |
| Kang, LS; LeBlanc, AJ; Muller-Delp, JM; Shipley, RD | 1 |
| Costa, CA; Criddle, DN; Espinoza, LA; Marins de Carvalho, LC; Ognibene, DT; Oliveira, PR; Resende, AC; Soares de Moura, R; Tano, T | 1 |
| Amour, J; Andriantsitohaina, R; Birenbaum, A; Heymes, C; Loyer, X; Michelet, P; Riou, B; Tesse, A | 1 |
| Anderson, MC; Connell, ML; Donato, AJ; Durrant, JR; Folian, BJ; Lesniewski, LA; Seals, DR | 1 |
| Abdel Aziz, MT; Atta, H; Fouad, H; Kamel, M; Mahfouz, S; Mostafa, T; Mouhamed, O; Rashed, L; Sabry, D; Wassef, M | 1 |
| Connell, ML; Donato, AJ; Durrant, JR; Folian, BJ; Lawson, BR; Lesniewski, LA; Russell, MJ; Seals, DR | 1 |
| Davidge, ST; Gragasin, FS | 1 |
| Berkowitz, DE; Bivalacqua, TJ; Bugaj, LJ; Camara, A; Champion, HC; Christianson, DW; Ilies, M; Kim, JH; Nyhan, D; Oh, YJ; Ryoo, S; Santhanam, L; Shoukas, AA; Sikka, G; Soucy, KG; Webb, A | 1 |
| Boegehold, MA; Frisbee, JC; Goodwill, AG; Samora, JB | 1 |
| Holowatz, LA; Jennings, JD; Kenney, WL; Lang, JA | 1 |
| Denvir, MA; Gray, GA | 1 |
| Coppinger, BJ; Miller, SJ; Unthank, JL; Zhou, X | 1 |
| Huang, A; Kaley, G; Sun, D; Yang, YM | 1 |
| Dailey, RA; Kang, LS; LeBlanc, AJ; Moningka, NC; Muller-Delp, JM; Reyes, R; Stallone, JN | 1 |
| Anderson, JE; Leiter, JR | 1 |
| Hobara, N; Jin, X; Kawasaki, H; Kitamura, Y; Koyama, T; Li, S; Satoh-Otonashi, Y; Sun, P; Zamami, Y | 1 |
| Li, S; Tang, YY; Wang, C; Wang, W | 1 |
| Davidge, ST; Morton, JS; Rueda-Clausen, CF | 1 |
| Inukai, N; Miyazaki, Y; Morita, H; Suzuki, T; Takizawa, T; Tanaka, K; Uchida, M; Yoshikawa, H | 1 |
| Marshall, JM; Omar, NM | 2 |
| Berkowitz, DE; Flavahan, NA; Flavahan, S; Goel, A; Lowenstein, CJ; Su, B | 1 |
| Mazet, B; Merrot, T; Wittmeyer, V | 1 |
| Heman-Ackah, SE; Huang, TC; Juhn, SK; Wiedmann, TS | 1 |
| Czabanka, M; Eklund, L; Heljasvaara, R; Ilves, M; Janmey, P; Kerkelä, R; Leskinen, H; Peuhkurinen, K; Pihlajaniemi, T; Piuhola, J; Rasi, K; Ruskoaho, H; Rysä, J; Sormunen, R; Vajkoczy, P; Vuolteenaho, O | 1 |
| Bridenbaugh, EA; Gashev, AA; Nagai, T | 1 |
| Emel'yanov, MO; Kim, YA; Korystov, YN; Korystova, AF; Kublik, LN; Levitman, MKh; Shaposhnikova, VV | 1 |
| Donato, AJ; Durrant, JR; Lawson, BR; Lesniewski, LA; Magerko, KA; Seals, DR | 1 |
| Copp, SW; Hageman, KS; Hirai, DM; Musch, TI; Poole, DC | 1 |
| Emel'yanov, MO; Korystov, YN; Korystova, AF; Kublik, LN; Levitman, MKh; Shaposhnikova, VV | 1 |
| Akl, TJ; Coté, GL; Gashev, AA; Nagai, T | 1 |
| Ebenezar, KK; Smith, FG; Wong, AK | 1 |
| Anjum, S; Banerjee, A; Krishna, A; Verma, R | 1 |
| Clavreul, N; Isabelle, M; Ragonnet, C; Sansilvestri-Morel, P; Simonet, S; Vayssettes-Courchay, C; Verbeuren, TJ | 1 |
| Borst, SE; Buford, TW; Calvani, R; Carter, CS; Diz, D; DuPree, J; Giovannini, S; Krotova, K; Lees, HA; Marzetti, E; Moningka, N; Morgan, D; Seo, DO; Strehler, KY; Sweet, K | 1 |
| Davidge, ST; Jiang, Y; Lekontseva, O; Schleppe, C | 1 |
| Behnke, BJ; Delp, MD; Dominguez, JM; Donato, AJ; Lesniewski, LA; Muller-Delp, J; Park, Y; Prisby, RD | 1 |
| Copp, SW; Ferguson, SK; Hirai, DM; Holdsworth, CT; Musch, TI; Poole, DC | 1 |
| Allen, MR; Delp, MD; Dominguez, JM; Muller-Delp, J; Prisby, RD | 1 |
| Arutyunyan, TV; Korystov, YN; Korystova, AF; Kublik, LN; Levitman, MKh; Shaposhnikova, VV | 1 |
| Fujimoto, S; Ihoriya, C; Kashihara, N; Kidokoro, K; Nagasu, H; Nishi, Y; Ozeki, M; Sasaki, T; Satoh, M | 1 |
| Ağar, A; Bîlmen, S; Gümüşlü, S; Hacioğlu, G; Ozdemir, S; Yargiçoğlu, P | 1 |
| Delp, MD; Muller-Delp, JM; Ramsey, MW; Spier, SA | 1 |
| Buchholz, JN; Geary, GG; Pearce, WJ | 1 |
| Harding, AW; Holowatz, LA; Houghton, BL; Kenney, WL; Minson, CT; Wilkins, BW; Wong, BJ | 1 |
| Tobisawa, M; Yamaguchi, M | 1 |
| Balfagón, G; Ferrer, M; Salaices, M; Sánchez, M | 1 |
| Dobesová, Z; Kunes, J; Pechánová, O; Zicha, J | 1 |
| Khalil, RA; Payne, JA; Reckelhoff, JF | 1 |
| Buchholz, JN; Geary, GG | 1 |
| Fernandez-Salguero, PM; Merino, JM; Mulero-Navarro, S; Pozo-Guisado, E; Santiago-Josefat, B | 1 |
| Aïtoubah, J; Itaya, S; Molotchnikoff, S | 1 |
| Delp, MD; Donato, AJ; Meininger, CJ; Muller-Delp, JM; Ramsey, MW; Spier, SA | 1 |
| Davidge, ST; Hemmings, DG; Xu, Y | 1 |
| Chaikomin, R; Gentilcore, D; Horowitz, M; Jones, KL; Russo, A; Stevens, JE; Tonkin, A; Visvanathan, R; Wishart, JM | 1 |
| Muller-Delp, JM; Shipley, RD | 1 |
| Llorens, S; Nava, E; Salazar, FJ | 1 |
| Briones, AM; Giraldo, J; Montoya, N; Vila, E | 1 |
| Andriantsitohaina, R; de Sotomayor, MA; Herrrera, MD; Jimenez, L; Marhuenda, E; Marín, R; Pérez-Guerrero, C | 1 |
| Berkowitz, DE; Bugayenko, A; Haile, A; Irani, K; Jeon, BH; Kasuno, K; Khanday, FA; Mattagajasingh, I; Qi, B; White, AR; Yamamori, T | 1 |
| Ariznavarreta, C; Cachofeiro, V; Castillo, C; Cruzado, M; Gil-Loyzaga, P; Lahera, V; Tresguerres, JA | 1 |
| Aita, T; Ishihata, A; Ito, T; Kaga, M; Katano, Y; Ohwada, K; Shimoda, T; Tomoike, H | 1 |
| Ibarra, M; López-Guerrero, JJ; Mejía-Zepeda, R; Villalobos-Molina, R | 1 |
| Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M | 1 |
| Fisher, ND; Hollenberg, NK; Sorond, FA | 1 |
| Ferri, C; Grassi, D; Grassi, G | 1 |
| Fisher, ND; Hollenberg, NK | 1 |
| Aaronson, PI; Knock, GA; Mahn, K; Mann, GE; Ward, JP | 1 |
| Delp, MD; Donato, AJ; Lesniewski, LA | 1 |
| Cardinali, DP; Linares, LM; Obaya-Naredo, D; Pinto, JE; Planells, FM; Reyes-Toso, CF; Ricci, CR | 1 |
| Eisenach, JH; Joyner, MJ; Schrage, WG | 1 |
| Frohlich, ED; Zhou, X | 1 |
| Delp, MD; Dominguez, JM; Muller-Delp, JM; Spier, SA; Stallone, JN | 1 |
| Allen, MR; Behnke, BJ; Delp, MD; Dominguez, JM; Donato, AJ; Prisby, RD; Ramsey, MW | 1 |
| Ishiguro, K; Itoh, H; Sakamaki, Y; Saruta, T; Sasamura, H | 1 |
| Edwards, J; Gao, Q; Huang, A; Jacobson, A; Kaley, G; Rincon-Skinner, T; Rivera, A; Sun, D; Yan, C | 1 |
| Javorková, V; Kunes, J; Pechanova, O; Vlkovicova, J; Vrbjar, N; Zicha, J | 1 |
| Larson, DF; Rohdewald, PJ; Watson, RR; Yu, Q; Zibadi, S | 1 |
| Benter, IF; Kehinde, EO; Yousif, MH | 1 |
| Dreshaj, IA; Haxhiu, MA; Kamath, S; Martin, RJ; Sopi, RB; Zaidi, SI | 1 |
| de Cabo, C; de Mera, RM; Jordán, J; Lloréns, S; Mendizábal, Y; Nava, E; Pascual, A; Prieto-Martín, A | 1 |
| Cañuelo, A; Martínez-Lara, E; Martínez-Romero, R; Peinado, MA; Siles, E | 1 |
| Estrada, C; Moreno-López, B; Romero-Grimaldi, C | 1 |
| Behnke, BJ; Delp, MD; Muller-Delp, JM; Spier, SA; Wu, G | 1 |
| Bradfield, CA; FitzGerald, GA; Kaneko, S; Katsuno, T; Komuro, I; Kunieda, T; Minamino, T; Miura, K; Miyauchi, H; Tateno, K | 1 |
| Adams, MA; Beharry, RKS; Hale, TM; Heaton, JPW; Shamloul, R | 1 |
| Alvarez de Sotomayor, M; Andriantsitohaina, R; Mingorance, C | 1 |
| Aggarwal, NT; Campbell, WB; Gauthier, KM | 1 |
| Black, MA; Cable, NT; Green, DJ | 1 |
| Arranz, C; Arreche, N; Balaszczuk, AM; Fellet, A; López, M; López-Costa, J | 1 |
| Moliken, W; Russo, P; Wagerle, LC | 1 |
| Bowyer, JF | 1 |
| Griffith, TM; Hutcheson, IR; Smith, JA | 1 |
| Freedman, A; Garbán, H; González-Cadavid, N; Rajfer, J; Vernet, D | 1 |
| Baird, JD; Lindsay, RM; McIntyre, MA; Rossiter, SP; Smith, W; Williams, BC | 1 |
| Aliev, G; Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Prosdocimi, M; Ragazzi, E | 1 |
| Lang, MG; Lüscher, TF; Noll, G | 1 |
| Amerini, S; Ledda, F; Mantelli, L | 1 |
| Bliss, TV; Errington, ML; Li, YG; Murphy, KP; Nayak, A; Williams, JH | 1 |
| Mancusi, G; Raberger, G; Schütz, W; Sexl, V | 1 |
| Anderson, S; Houghton, DC; Tank, JE; Vora, JP | 1 |
| Arribas, S; Balfagón, G; Marín, J; Ponte, A; Salaices, M | 1 |
| Andreucci, VE; Conte, G; De Nicola, L; Giliberti, A; Margri, P; Sabbatini, M; Sansone, G; Sepe, V; Uccello, F | 1 |
| Joshua, IG; Li, F | 1 |
| Hasegawa, K; Khosla, MC; Nishimura, H | 1 |
| Cai, L; Garban, H; Gonzalez-Cadavid, NF; Marquez, D; Rajfer, J | 1 |
| Farr, S; Flood, JF; Kumar, VB; Mattammal, MB; Morley, JE; Morley, PM | 1 |
| Aguilar, E; Aguilar, R; González, D; Pinilla, L; Tena-Sempere, M | 2 |
| Hata, I; Hata, K; Ishii, Y; Miura, M; Muramatsu, I; Sudo, M; Tsuchida, S; Tsukahara, H; Yamamoto, K | 1 |
| Davidge, ST; Hubel, CA; McLaughlin, MK | 1 |
| Frohlich, ED | 1 |
| Nabeshima, T; Noda, Y; Yamada, K | 1 |
| Araki, T; Fujiwara, T; Itoyama, Y; Kato, H; Shuto, K | 1 |
| Gozal, D; Gozal, E; Gozal, YM; Hornby, PJ; Nuckton, TJ; Torres, JE | 1 |
| Pinto, A; Sorrentino, R | 1 |
| Arribas, SM; Giraldo, J; Tabernero, A; Vila, E; Vivas, NM | 1 |
| Baylis, C; Engels, K; Hill, C; Lateef, AM; Samsell, L | 1 |
| Reckelhoff, JF | 1 |
| Dreshaj, IA; Ernsberger, P; Haxhiu, MA; Jakupaj, M; Martin, RJ; Potter, CF | 1 |
| Goebels, J; Heremans, H; Kuschnaroff, LM; Matthys, P; Valckx, D; Waer, M | 1 |
| Bredt, DS; Comtois, A; El Dwairi, Q; Greenwood, MT; Guo, Y; Hussain, SN; Zhu, E | 1 |
| Ioroi, T; Nakamura, H; Yonetani, M | 1 |
| Kulkarni, SK; Reddy, DS | 1 |
| Harb, R; Lincoln, J | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Konishi, C; Naito, Y; Ohara, N | 2 |
| Dreshaj, IA; Haxhiu, MA; Martin, RJ; Mhanna, MJ | 1 |
| Cella, SG; Marazzi, N; Müller, EE; Rigamonti, AE | 1 |
| Buchholz, J; Duckles, SP; Edwards-Teunissen, K | 1 |
| Brown, RA; Natavio, M; Ren, J; Sowers, JR | 1 |
| Almeida, A; Bolaños, JP; Medina, JM | 1 |
| Amrani, M; Goodwin, AT; Gray, CC; Jayakumar, J; Marchbank, AJ; Yacoub, MH | 1 |
| Davidge, ST; O'brien, SF; Russell, JC | 1 |
| Borgonio, A; Lemmer, B; Stahrenberg, R; Witte, K | 1 |
| Brown, RA; Jefferson, L; Ren, J; Sowers, JR | 1 |
| Abernethy, DR; Andrawis, N; Jones, DS | 1 |
| Artuso, A; Bouriquet, N; Casellas, D | 1 |
| Chamiot-Clerc, P; Choukri, N; Droy-Lefaix, MT; Legrand, M; Renaud, JF; Safar, ME | 1 |
| Baena, AB; Diez-Picazo, LD; Garcia-Cohen, EC; Marin, J; Rodriguez-Martinez, MA; Salaices, M | 1 |
| Dworkin, LD; Feiner, HD; Tolbert, EM; Weisstuch, J | 1 |
| Laverty, R; Ledingham, JM; Orange, SJ | 1 |
| Barr, GA; Zhu, H | 1 |
| Dreshaj, IA; Farver, CF; Haxhiu, MA; Iben, SC; Martin, RJ | 1 |
| Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M | 1 |
| Headrick, JP; Hinschen, AK; Rose'Meyer, RB | 1 |
| Asai, K; Kudej, AB; Kudej, RK; Natividad, F; Shen, YT; Takagi, G; Vatner, DE; Vatner, SF | 1 |
| Balfagón, G; Ferrer, M | 1 |
| Sener, A; Smith, FG | 2 |
| Gangula, PR; Thompson, ML; Witlin, AG; Yallampalli, C | 1 |
| Dobesová, Z; Kunes, J; Zicha, J | 1 |
| Csiszar, A; Edwards, JG; Kaley, G; Kaminski, P; Koller, A; Ungvari, Z; Wolin, MS | 1 |
| Chun, MH; Jung, CS; Kim, KY; Kwon, SO; Lee, EJ; Lee, MY; Oh, SJ; Park, SJ | 1 |
| Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW | 1 |
| Hisayama, T; Moritoki, H; Takeuchi, S; Yoshikawa, T | 1 |
| Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S | 1 |
1 review(s) available for ng-nitroarginine methyl ester and Aging
| Article | Year |
|---|---|
Analogy of cardiac and renal complications in essential hypertension and aged SHR or L-NAME/SHR.
Topics: Aging; Animals; Antihypertensive Agents; Disease Models, Animal; Enzyme Inhibitors; Heart Diseases; Hypertension; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR | 2007 |
3 trial(s) available for ng-nitroarginine methyl ester and Aging
| Article | Year |
|---|---|
Nitric oxide and attenuated reflex cutaneous vasodilation in aged skin.
Topics: Adult; Aged; Aging; Body Temperature Regulation; Enzyme Inhibitors; Fever; Humans; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Reflex; Regional Blood Flow; Skin; Skin Temperature; Vasodilation | 2003 |
Role of nitric oxide mechanisms in gastric emptying of, and the blood pressure and glycemic responses to, oral glucose in healthy older subjects.
Topics: Administration, Oral; Age Factors; Aged; Aging; Blood Pressure; Double-Blind Method; Enzyme Inhibitors; Female; Gastric Emptying; Glucose; Heart Rate; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Postprandial Period | 2005 |
Ageing reduces nitric-oxide- and prostaglandin-mediated vasodilatation in exercising humans.
Topics: Aged; Aged, 80 and over; Aging; Blood Pressure; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Forearm; Heart Rate; Humans; Hyperemia; Ketorolac; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Physical Exertion; Prostaglandins; Regional Blood Flow; Signal Transduction; Vasodilation | 2007 |
174 other study(ies) available for ng-nitroarginine methyl ester and Aging
| Article | Year |
|---|---|
Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice.
Topics: Aging; Animals; Catalase; Cerebrovascular Circulation; Enzyme Inhibitors; Lasers; Mice, Inbred C57BL; Mice, Transgenic; Microcirculation; Mitochondria; Neurovascular Coupling; NG-Nitroarginine Methyl Ester | 2019 |
Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging.
Topics: Aging; Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Female; Hemodynamics; Hypertension; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phenotype; Sodium Chloride, Dietary | 2020 |
Age-Specific Characteristics of CO-Mediated Reaction of the Pial Arteries of Various Diameters in Rats.
Topics: Aging; Animals; Arginine; Carbon Monoxide; Cerebral Arteries; Hemin; Male; NG-Nitroarginine Methyl Ester; Protoporphyrins; Rats, Wistar; Signal Transduction; Vasodilation | 2017 |
Glomerular and tubular effects of nitric oxide (NO) are regulated by angiotensin II (Ang II) in an age-dependent manner through activation of both angiotensin receptors (AT1Rs and AT2Rs) in conscious lambs.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Male; Nephrons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Angiotensin; Sheep; Urodynamics; Wakefulness; Water-Electrolyte Balance | 2018 |
Age-associated urethral dysfunction in urethane-anesthetized rats.
Topics: Age Factors; Aging; Anesthetics, Intravenous; Animals; Enzyme Inhibitors; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Urethane; Urethra; Urinary Bladder Diseases; Urination | 2018 |
Age-Dependent Effects of NO on Rhythmic Activity of Postganglionic Sympathetic Fibers.
Topics: Aging; Animals; Female; Ganglia, Sympathetic; NG-Nitroarginine Methyl Ester; Nitroprusside; Rats; Rats, Wistar; Sympathetic Fibers, Postganglionic | 2019 |
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril.
Topics: Aging; Anesthetics, Intravenous; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve; Blood Pressure; Captopril; Endothelium, Vascular; Enzyme Inhibitors; Methacholine Chloride; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2013 |
Aging-related endothelial dysfunction in the aorta from female senescence-accelerated mice is associated with decreased nitric oxide synthase expression.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Endothelium, Vascular; Female; Gene Expression; Mice; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phenylephrine; Vasoconstriction | 2013 |
Aging compounds western diet-associated large artery endothelial dysfunction in mice: prevention by voluntary aerobic exercise.
Topics: Aging; Animals; Carotid Arteries; Cyclic N-Oxides; Diet; Endothelium, Vascular; Free Radical Scavengers; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Spin Labels; Superoxides; Vascular Stiffness; Vasodilation | 2013 |
Effect of age on the contractile response of the rat carotid artery in the presence of sympathetic drugs and L-NAME.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Carotid Arteries; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Rats; Vasodilator Agents | 2013 |
Diminished nitric oxide-dependent sweating in older males during intermittent exercise in the heat.
Topics: Adult; Aged; Aging; Body Temperature; Exercise; Hot Temperature; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Sweating; Young Adult | 2014 |
Blood pressure variability, impaired autonomic function and vascular senescence in aged spontaneously hypertensive rats are ameliorated by angiotensin blockade.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Autonomic Nervous System; Baroreflex; beta-Galactosidase; Blood Pressure; Drug Evaluation, Preclinical; Endothelium, Vascular; Hypertension; Imidazoles; Myocardium; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Norepinephrine; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex, Abnormal; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation | 2014 |
Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function?
Topics: Adrenergic Agonists; Aging; Animals; Aorta; Enzyme Inhibitors; Focal Adhesions; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Phenylephrine; Pyrimidines; src-Family Kinases; Stress, Mechanical; Vascular Stiffness | 2014 |
Propofol-induced relaxation of rat aorta is altered by aging.
Topics: Aging; Anesthetics, Intravenous; Animals; Aorta, Thoracic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Propofol; Rats; Rats, Wistar; Vasodilation | 2014 |
Vascular endothelial function is improved by oral glycine treatment in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Endothelium, Vascular; Glycine; Humans; Indomethacin; Interleukin-1beta; Male; NADPH Oxidase 4; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrobenzenes; Phenylephrine; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Aging; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Endothelium, Vascular; Enzyme Inhibitors; Fumarates; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Inbred F344; Renin; Renin-Angiotensin System; Valsartan; Vasodilation | 2016 |
Experimental reduction of miR-92a mimics arterial aging.
Topics: Adult; Aged; Aging; Animals; Aorta; Endothelium, Vascular; Female; Humans; Male; Mice; MicroRNAs; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulse Wave Analysis; Up-Regulation; Vascular Stiffness | 2016 |
Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats.
Topics: Aging; Animals; Enteric Nervous System; Immunohistochemistry; Interstitial Cells of Cajal; Male; Myenteric Plexus; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Proto-Oncogene Proteins c-kit; Rats; Rats, Inbred F344; RNA, Messenger; Stem Cell Factor; Stomach | 2017 |
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Disease Models, Animal; Extracellular Matrix; Gait; Hypertension; Infusion Pumps, Implantable; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenotype; Psychomotor Performance | 2017 |
Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Arginine; Behavior, Animal; Catalase; Enzyme Inhibitors; Exploratory Behavior; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase | 2008 |
Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles.
Topics: Acetylcholine; Age Factors; Aging; Androstadienes; Animals; Arterioles; Blood Flow Velocity; Cinnamates; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Stress, Mechanical; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vasodilation; Vasodilator Agents; Wortmannin | 2008 |
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation | 2009 |
Involvement of beta 3-adrenoceptor in altered beta-adrenergic response in senescent heart: role of nitric oxide synthase 1-derived nitric oxide.
Topics: Age Factors; Aging; Animals; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptors, Adrenergic, beta-3 | 2008 |
B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Superoxides; Tyrosine; Vascular Resistance; Vasodilation; Vasodilator Agents | 2009 |
Effect of HO-1 cDNA-liposome complex transfer on erectile signalling of aged rats.
Topics: Aging; Animals; Carbon Monoxide; DNA, Complementary; Enzyme Activation; Erectile Dysfunction; Gene Expression; Gene Transfer Techniques; Guanylate Cyclase; Heme Oxygenase-1; Liposomes; Male; NG-Nitroarginine Methyl Ester; Penile Erection; Rats; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Soluble Guanylyl Cyclase | 2009 |
Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase.
Topics: Acetophenones; Acetylcholine; Aging; Animals; Carotid Arteries; Down-Regulation; Endothelium, Vascular; In Vitro Techniques; Male; Mice; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Physical Exertion; Superoxide Dismutase; Tyrosine; Vasodilation | 2009 |
The effects of propofol on vascular function in mesenteric arteries of the aging rat.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Biological Factors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Hypnotics and Sedatives; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phenylephrine; Propofol; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Topics: Acetylcholine; Age Factors; Aging; Aminocaproates; Animals; Aorta; Arginase; Boron Compounds; Carotid Arteries; Compliance; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Protein Multimerization; Rats; Rats, Inbred F344; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2009 |
Growth-dependent changes in the contribution of carbon monoxide to arteriolar function.
Topics: Acetylcholine; Age Factors; Aging; Aminolevulinic Acid; Animals; Animals, Newborn; Arterioles; Carbon Dioxide; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Heme Oxygenase (Decyclizing); In Vitro Techniques; Male; Mesoporphyrins; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Age Factors; Aged; Aging; Blood Flow Velocity; Blood Pressure; Blood Vessels; Body Temperature Regulation; Cold Temperature; Female; Forearm; Humans; Laser-Doppler Flowmetry; Male; Microdialysis; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Protein Kinase Inhibitors; Reflex; Regional Blood Flow; rho-Associated Kinases; Skin; Vasoconstriction; Vasodilator Agents; Young Adult | 2009 |
Run for your life: exercise, oxidative stress and the ageing endothelium.
Topics: Acetophenones; Acetylcholine; Aging; Animals; Carotid Arteries; Down-Regulation; Endothelium, Vascular; Male; Mice; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Physical Exertion; Superoxide Dismutase; Tyrosine; Vasodilation | 2009 |
Antioxidants reverse age-related collateral growth impairment.
Topics: Acetophenones; Age Factors; Aging; Animals; Antioxidants; Collateral Circulation; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Ileum; Ligation; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred WKY; Rats, Wistar; RNA, Messenger; Spin Labels | 2010 |
eNOS uncoupling and endothelial dysfunction in aged vessels.
Topics: Acetylcholine; Age Factors; Aging; Alcohol Oxidoreductases; Animals; Biopterins; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Enzyme Stability; GTP Cyclohydrolase; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidation-Reduction; Protein Multimerization; Pterins; Superoxides; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents | 2009 |
Estrogen replacement restores flow-induced vasodilation in coronary arterioles of aged and ovariectomized rats.
Topics: Age Factors; Aging; Animals; Arterioles; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Drug Implants; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Female; Hydrazines; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Ovariectomy; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred F344; RNA, Messenger; Vasodilation | 2009 |
Satellite cells are increasingly refractory to activation by nitric oxide and stretch in aged mouse-muscle cultures.
Topics: Aging; Animals; Cells, Cultured; Female; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Satellite Cells, Skeletal Muscle; Stress, Mechanical | 2010 |
Age-related disappearance of the inhibitory effect of vascular endothelium on agonist-induced vasoconstriction in rat mesenteric vascular beds.
Topics: Acetylcholine; Aging; Animals; Benzoquinones; Biological Factors; Calcimycin; Catalase; Cyclic N-Oxides; Deoxycholic Acid; Drug Interactions; Endothelium, Vascular; Heptanoic Acids; Indomethacin; Male; Methoxamine; NG-Nitroarginine Methyl Ester; Potassium Chloride; Rats; Rats, Wistar; Spin Labels; Splanchnic Circulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Possible involvement of NO/NOS signaling in hippocampal amyloid-beta production induced by transient focal cerebral ischemia in aged rats.
Topics: Acute Disease; Aging; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Death; Enzyme Inhibitors; Hippocampus; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors | 2010 |
Mechanisms of endothelium-dependent vasodilation in male and female, young and aged offspring born growth restricted.
Topics: Aging; Animals; Arteries; Biological Factors; Body Weight; Female; Fetal Growth Retardation; Humans; Hypoxia; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstriction; Vasodilation | 2010 |
Nitric oxide production and its contribution to hepatocyte proliferation in normal juvenile rats.
Topics: Aging; Animals; Cell Division; DNA Primers; Hepatocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Reference Values; RNA, Messenger | 2010 |
Age-related changes in the sympathetic innervation of cerebral vessels and in carotid vascular responses to norepinephrine in the rat: in vitro and in vivo studies.
Topics: Age Factors; Aging; Animals; Basilar Artery; Blood Pressure; Carotid Arteries; Cerebrovascular Circulation; Enzyme Inhibitors; Femoral Artery; Heart Rate; Infusions, Intravenous; Male; Middle Cerebral Artery; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Age-related changes in carotid vascular responses to adenosine and nitric oxide in the rat: in vitro and in vivo studies.
Topics: Adenosine; Age Factors; Aging; Animals; Blood Pressure; Carotid Artery, Common; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Infusions, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2010 |
Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.
Topics: Age Factors; Aging; Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Exocytosis; Fluorescent Antibody Technique; Glycopeptides; Hydrazines; In Vitro Techniques; Mesenteric Arteries; Metalloendopeptidases; N-Ethylmaleimide-Sensitive Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Peptides, Cyclic; Rats; Rats, Inbred F344; Receptor, Endothelin A; RNA, Messenger; Sulfonamides; Sulfonylurea Compounds; Thrombin; Up-Regulation; Vasoconstriction; von Willebrand Factor | 2010 |
Tonic inhibition of human small intestinal motility by nitric oxide in children but not in adults.
Topics: Adult; Aged; Aging; Atropine; Child; Electric Stimulation; Electromyography; Enzyme Inhibitors; Female; Gastrointestinal Motility; Humans; In Vitro Techniques; Intestine, Small; Male; Middle Aged; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 2010 |
A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice.
Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Auditory Threshold; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Glutathione; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Presbycusis; Vitamin B Complex | 2010 |
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomyopathies; Collagen; Coronary Circulation; Disease Models, Animal; Echocardiography; Elasticity; Enzyme Inhibitors; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Genotype; Heart Ventricles; Hemodynamics; Hypertension; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Electron; Microscopy, Video; Myocardium; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Polymerase Chain Reaction; RNA, Messenger; Telemetry; Ventricular Remodeling | 2010 |
Aging-associated alterations in contractility of rat mesenteric lymphatic vessels.
Topics: Aging; Animals; Enzyme Inhibitors; Lymphatic Vessels; Male; Mesentery; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred F344 | 2011 |
Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of L-NAME.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Aorta; Aorta, Thoracic; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Wistar; Reference Values | 2012 |
SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aging; Animals; Arteries; Benzamides; Cells, Cultured; Endothelium, Vascular; Female; Humans; Male; Mice; Mice, Inbred Strains; Middle Aged; Models, Animal; Naphthols; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Sirtuin 1; Vasodilation; Young Adult | 2011 |
Aging alters the contribution of nitric oxide to regional muscle hemodynamic control at rest and during exercise in rats.
Topics: Aging; Animals; Blood Pressure; Hemodynamics; Hindlimb; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Regional Blood Flow; Rest; Vasodilation; Vasomotor System | 2011 |
Low doses of ethanol decrease the activity of the angiotensin-converting enzyme in the aorta of aging rats and rats treated with a nitric oxide synthase inhibitor and dexamethasone.
Topics: Aging; Alcohol Drinking; Animals; Aorta; Cardiovascular Diseases; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Risk Factors; Thymus Gland | 2012 |
Mesenteric lymph flow in adult and aged rats.
Topics: Age Factors; Aging; Animals; Biomechanical Phenomena; Enzyme Inhibitors; Lymph; Lymphatic Vessels; Male; Mesentery; Microscopy, Video; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulsatile Flow; Rats; Rats, Inbred F344; Stress, Mechanical; Time Factors | 2011 |
Haemodynamic responses to angiotensin II in conscious lambs: role of nitric oxide and prostaglandins.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Cyclooxygenase Inhibitors; Female; Hemodynamics; Indomethacin; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Renal Circulation; Sheep, Domestic; Vasoconstriction | 2012 |
Alteration in expression of estrogen receptor isoforms alpha and beta, and aromatase in the testis and its relation with changes in nitric oxide during aging in mice.
Topics: 3-Hydroxysteroid Dehydrogenases; Aging; Animals; Aromatase; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroprusside; Phosphoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Testis; Testosterone | 2012 |
Chronic reduction of nitric oxide level in adult spontaneously hypertensive rats induces aortic stiffness similar to old spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Clonidine; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Stiffness | 2012 |
Late-life enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscle.
Topics: Adaptation, Physiological; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Energy Metabolism; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred BN; Rats, Inbred F344 | 2013 |
Altered neuronal nitric oxide synthase in the aging vascular system: implications for estrogens therapy.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Estradiol; Female; In Vitro Techniques; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Ovariectomy; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine | 2012 |
Effects of aging, TNF-α, and exercise training on angiotensin II-induced vasoconstriction of rat skeletal muscle arterioles.
Topics: Aging; Angiotensin II; Animals; Arterioles; Education; Endothelium, Vascular; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 2012 |
Effects of neuronal nitric oxide synthase inhibition on microvascular and contractile function in skeletal muscle of aged rats.
Topics: Acetylcholine; Aging; Animals; Citrulline; Enzyme Inhibitors; Hemodynamics; Male; Microcirculation; Models, Biological; Muscle Contraction; Muscle Strength; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxygen Consumption; Rats; Rats, Inbred BN; Rats, Inbred F344; Regional Blood Flow; Thiourea; Vasodilator Agents | 2012 |
Aging and estrogen status: a possible endothelium-dependent vascular coupling mechanism in bone remodeling.
Topics: Aging; Animals; Arteries; Bone and Bones; Bone Remodeling; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Estrogen Replacement Therapy; Estrogens; Female; Hydrazines; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Ovariectomy; Rats; Rats, Inbred F344; Regression Analysis; Vasodilator Agents | 2012 |
Effects of taxifolin on the activity of angiotensin-converting enzyme and reactive oxygen and nitrogen species in the aorta of aging rats and rats treated with the nitric oxide synthase inhibitor and dexamethasone.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atherosclerosis; Dexamethasone; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Glucocorticoids; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species | 2013 |
Angiostatin production increases in response to decreased nitric oxide in aging rat kidney.
Topics: Aging; Angiostatins; Animals; Blotting, Western; Cathepsin D; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Kidney; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Statistics, Nonparametric | 2013 |
Role of nitric oxide on age-dependent alterations: investigation of electrophysiologic and biochemical parameters.
Topics: Aging; Animals; Antioxidants; Arginine; Brain; Enzyme Inhibitors; Evoked Potentials, Visual; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrous Acid; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 2002 |
Aging impairs endothelium-dependent vasodilation in rat skeletal muscle arterioles.
Topics: Acetylcholine; Adenosine; Aging; Animals; Arterioles; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Inbred F344; Stress, Mechanical; Vasodilation; Vasodilator Agents | 2002 |
Maturation depresses mouse cerebrovascular tone through endothelium-dependent mechanisms.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Cerebral Arteries; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Time Factors; Vasomotor System | 2003 |
Inhibitory role of regucalcin in the regulation of nitric oxide synthase activity in rat brain cytosol: involvement of aging.
Topics: Age Factors; Aging; Animals; Antibodies, Monoclonal; Brain Chemistry; Calcium Chloride; Calcium-Binding Proteins; Calmodulin; Carboxylic Ester Hydrolases; Chelating Agents; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfotransferases; Trifluoperazine | 2003 |
Different effects of acute clenbuterol on vasomotor response in mesenteric arteries from young and old spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Clenbuterol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred SHR; Tetrodotoxin; Tritium; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Hypertensive response to chronic NG-nitro-L-arginine methyl ester (L-NAME) treatment is similar in immature and adult Wistar rats.
Topics: Aging; Animals; Aorta; Heart Ventricles; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sodium Chloride, Dietary; Weaning | 2003 |
Role of oxidative stress in age-related reduction of NO-cGMP-mediated vascular relaxation in SHR.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Phenylephrine; Rats; Rats, Inbred SHR; Vasoconstrictor Agents; Vasodilation | 2003 |
Selected contribution: Effects of aging on cerebrovascular tone and [Ca2+]i.
Topics: Aging; Animals; Body Weight; Calcium; Cerebrovascular Circulation; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Intracellular Membranes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Osmolar Concentration; Pressure; Rats; Rats, Inbred F344; Vasomotor System | 2003 |
Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: role of nitric oxide accumulation.
Topics: Aging; Aniline Compounds; Animals; Animals, Newborn; Calcimycin; Calcium; Cells, Cultured; Cellular Senescence; Cerebellum; Citrulline; Copper Sulfate; Cytochrome P-450 CYP1A2; Dizocilpine Maleate; DNA-Binding Proteins; Down-Regulation; Enzyme Induction; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluoresceins; Ionophores; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tritium; Xanthenes | 2003 |
Nitric oxide and its influence on oscillations of collicular responses in developing rats.
Topics: Aging; Animals; Animals, Newborn; Arginine; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Evoked Potentials; Immunohistochemistry; Models, Neurological; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Periodicity; Rats; Rats, Long-Evans; Superior Colliculi | 2003 |
Effects of ageing and exercise training on endothelium-dependent vasodilatation and structure of rat skeletal muscle arterioles.
Topics: Acetylcholine; Aging; Animals; Arterioles; Blotting, Western; Body Weight; Citrate (si)-Synthase; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Indomethacin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Physical Conditioning, Animal; Rats; Rats, Inbred F344; RNA, Messenger; Vasodilation | 2004 |
Sphingosine 1-phosphate-induced vasoconstriction is elevated in mesenteric resistance arteries from aged female rats.
Topics: Aging; Animals; Canada; Drug Implants; Estradiol; Estrogen Replacement Therapy; Female; Fluorescent Antibody Technique; Gene Expression; Lysophospholipids; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Vascular Resistance; Vasoconstriction | 2004 |
Aging decreases vasoconstrictor responses of coronary resistance arterioles through endothelium-dependent mechanisms.
Topics: Aging; Animals; Arterioles; Blood Pressure; Coronary Circulation; Endothelins; Endothelium, Vascular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; Piperidines; Potassium Chloride; Rats; Rats, Inbred F344; Receptors, Endothelin; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Assessment of the nitric oxide system in the heart, aorta and kidney of aged Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Ventricles; Kidney; Kidney Cortex; Kidney Medulla; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation | 2005 |
Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries.
Topics: Acetylcholine; Aging; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitrobenzenes; Oxidative Stress; Phenylephrine; Rats; Rats, Sprague-Dawley; Sulfonamides; Up-Regulation; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways.
Topics: Acetylcholine; Aging; Animals; Aorta; Calcimycin; Cholesterol; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Simvastatin; Thromboxane B2; Triglycerides; Vasodilation; Vasodilator Agents | 2005 |
P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction.
Topics: Acetylcholine; Adaptor Proteins, Signal Transducing; Aging; Animals; Aorta; Chlorocebus aethiops; COS Cells; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Culture Techniques; Protein Processing, Post-Translational; Proto-Oncogene Mas; Rats; Rats, Inbred WKY; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Umbilical Veins; Vasodilation; Vasodilator Agents | 2005 |
Effect of recombinant human growth hormone administration on body composition and vascular function and structure in old male Wistar rats.
Topics: Acetylcholine; Adipose Tissue; Aging; Animals; Aorta, Thoracic; Body Composition; Dose-Response Relationship, Drug; Human Growth Hormone; Humans; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Recombinant Proteins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Progression of severe atherosclerosis and increased arterial pulse pressure in the newly developed heritable mixed hyperlipidaemic rabbits.
Topics: Aging; Animals; Aorta; Atherosclerosis; Blood Pressure; Body Weight; Cholesterol; Disease Progression; Electrocardiography; Enzyme Inhibitors; Hyperlipoproteinemia Type V; Hypertension; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rabbits; Triglycerides | 2006 |
Endothelium-dependent inhibition of the contractile response is decreased in aorta from aged and spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Disease Models, Animal; Endothelium; Hypertension; Indomethacin; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Serotonin | 2006 |
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
Topics: Aging; Arginine; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; NG-Nitroarginine Methyl Ester; Oxidative Stress; Telomerase; Time Factors | 2006 |
Cocoa flavanols and brain perfusion.
Topics: Aged; Aging; Beverages; Cacao; Cerebrovascular Circulation; Dementia, Vascular; Endothelium, Vascular; Flavonoids; Humans; Magnetic Resonance Imaging; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vasodilation | 2006 |
Cocoa beans, endothelial function and aging: an unexpected friendship?
Topics: Aging; Blood Pressure; Blood Volume; Cacao; Endothelium, Vascular; Enzyme Inhibitors; Fabaceae; Fingers; Flavonoids; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulsatile Flow; Regional Blood Flow; Vasodilation | 2006 |
Aging and vascular responses to flavanol-rich cocoa.
Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Blood Volume; Cacao; Endothelium, Vascular; Enzyme Inhibitors; Female; Fingers; Flavonoids; Humans; Male; Manometry; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulsatile Flow; Reference Values; Regional Blood Flow; Vasodilation | 2006 |
Dietary soy modulates endothelium-dependent relaxation in aged male rats: Increased agonist-induced endothelium-derived hyperpolarising factor and basal nitric oxide activity.
Topics: Acetylcholine; Aging; Animals; Apamin; Biological Factors; Charybdotoxin; Endothelium, Vascular; Glycine max; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Soybean Proteins | 2006 |
Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles.
Topics: Adrenergic beta-Agonists; Aging; Animals; Arterioles; Colforsin; Enzyme Inhibitors; Hindlimb; Isoproterenol; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2007 |
Effect of melatonin on vascular responses in aortic rings of aging rats.
Topics: Acetylcholine; Aging; Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Lipid Peroxidation; Male; Melatonin; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Exercise training enhances flow-induced vasodilation in skeletal muscle resistance arteries of aged rats: role of PGI2 and nitric oxide.
Topics: Age Factors; Aging; Animals; Arterioles; Blood Flow Velocity; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epoprostenol; Indomethacin; Male; Membrane Proteins; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Physical Exertion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Regional Blood Flow; RNA, Messenger; Signal Transduction; Up-Regulation; Vascular Resistance; Vasodilation; Vasodilator Agents | 2007 |
Aging reduces skeletal blood flow, endothelium-dependent vasodilation, and NO bioavailability in rats.
Topics: Acetylcholine; Aging; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium; Femur; Gene Expression Regulation, Enzymologic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Rats; Rats, Inbred F344; RNA, Messenger; Vasodilation | 2007 |
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Critical Period, Psychological; Drug Administration Schedule; Enzyme Inhibitors; Hypertension; Kidney; Male; Mortality; NG-Nitroarginine Methyl Ester; Oxidative Stress; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles; Vasoconstrictor Agents | 2007 |
Aging enhances pressure-induced arterial superoxide formation.
Topics: Acetophenones; Aging; Animals; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Inbred F344; Superoxides; Vasoconstriction; Xanthine Oxidase | 2007 |
Effect of maturation on renal Na+/K+-atpase and its susceptibility to nitric oxide-deficient hypertension in rats.
Topics: Adenosine Triphosphate; Age Factors; Aging; Animals; Binding Sites; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Kinetics; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Sodium Chloride; Sodium-Potassium-Exchanging ATPase | 2007 |
Impact of Pycnogenol on cardiac extracellular matrix remodeling induced by L-NAME administration to old mice.
Topics: Aging; Animals; Blood Pressure; Collagen; Cross-Linking Reagents; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Heart; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ventricular Remodeling | 2007 |
Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erectile Dysfunction; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penis; Peptide Fragments; Peptides; Potassium Channel Blockers; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma.
Topics: Aging; Animals; Animals, Newborn; Arginase; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Hyperoxia; In Vitro Techniques; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
The nitric oxide system response to hypoxia/reoxygenation in the aged cerebral cortex.
Topics: Aging; Animals; Cerebral Cortex; Gene Expression; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Age-dependent effect of nitric oxide on subventricular zone and olfactory bulb neural precursor proliferation.
Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Glutathione; Green Fluorescent Proteins; Lateral Ventricles; Mice; NADPH Dehydrogenase; Neural Cell Adhesion Molecule L1; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Olfactory Bulb; Sialic Acids; Stem Cells | 2008 |
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.
Topics: Aging; Animals; Arginase; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pterins; Rats; Rats, Inbred F344; Vasodilation | 2008 |
Reduced nitric oxide causes age-associated impairment of circadian rhythmicity.
Topics: Aging; Animals; Blood Pressure; Cell Cycle Proteins; Cells, Cultured; Chronobiology Disorders; Circadian Rhythm; Culture Media, Serum-Free; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nuclear Proteins; Period Circadian Proteins; Phosphorylation; Promoter Regions, Genetic; Time Factors; Transfection; Up-Regulation | 2008 |
Restoration of female genital vasocongestive arousal responses in young and aged rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Female; Genitalia, Female; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroprusside; Ovariectomy; Rats; Rats, Wistar; Regional Blood Flow; Sexual Behavior, Animal; Vasodilation; Vasodilator Agents | 2008 |
Cedrelopsis grevei improves endothelial vasodilatation in aged rats through an increase of NO participation.
Topics: Acetylcholine; Aging; Animals; Body Weight; Endothelium, Vascular; Magnoliopsida; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Systole; Vasodilation | 2008 |
15-Lipoxygenase metabolites contribute to age-related reduction in acetylcholine-induced hypotension in rabbits.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Age Factors; Aging; Animals; Apamin; Arachidonate 15-Lipoxygenase; Blood Pressure; Charybdotoxin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Hypotension; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channel Blockers; Rabbits; Vasodilation; Vasodilator Agents | 2008 |
Exercise prevents age-related decline in nitric-oxide-mediated vasodilator function in cutaneous microvessels.
Topics: Acetylcholine; Adult; Aging; Capillaries; Dose-Response Relationship, Drug; Exercise; Female; Hot Temperature; Humans; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Skin; Time Factors; Vasodilation | 2008 |
Hypovolemic state: involvement of nitric oxide in the aged related alterations of aquaporins-2 abundance in rat kidney.
Topics: Aging; Animals; Aquaporin 2; Blood Pressure; Blotting, Western; Enzyme Inhibitors; Hemorrhage; Hypovolemia; Immunohistochemistry; Kidney; Male; Microscopy, Immunoelectron; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Water | 2008 |
Nitric oxide and beta-adrenergic mechanisms modify contractile responses to norepinephrine in ovine fetal and newborn cerebral arteries.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Arginine; Cerebral Arteries; Embryonic and Fetal Development; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Propranolol; Receptors, Adrenergic, beta; Sheep; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
Abolition of flow-dependent EDRF release before that evoked by agonists in hypercholesterolaemic rabbits.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Viscosity; Cholesterol; Cholesterol, Dietary; Dextrans; Hypercholesterolemia; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits | 1994 |
Effect of aging on nitric oxide-mediated penile erection in rats.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Papaverine; Penile Erection; Penis; Rats; Rats, Inbred F344 | 1995 |
N omega-nitro-L-arginine methyl ester reduces the incidence of IDDM in BB/E rats.
Topics: Administration, Oral; Aging; Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 1; Female; Insulin; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred BB | 1995 |
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hyperlipidemia, Familial Combined; Male; Methylene Blue; Microscopy, Electron; Microscopy, Electron, Scanning; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Uridine Triphosphate | 1995 |
Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors.
Topics: Aging; Angiotensins; Animals; Arginine; Arteries; Blood Pressure; Body Weight; Endothelium, Vascular; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Biological Factors; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Tetraethylammonium Compounds; Vasodilation | 1995 |
The suppression of long-term potentiation in rat hippocampus by inhibitors of nitric oxide synthase is temperature and age dependent.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Hemoglobins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Temperature | 1993 |
Age-related changes in vascular reactivity in genetically diabetic rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Calcimycin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker | 1995 |
Altered renal vascular responses in the aging rat kidney.
Topics: Aging; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetrazoles | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Norepinephrine; Ouabain; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Yohimbine | 1994 |
Functional versus structural changes in the pathophysiology of acute ischemic renal failure in aging rats.
Topics: Acute Kidney Injury; Aging; Animals; Arginine; Dietary Proteins; Glomerular Filtration Rate; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiourea | 1994 |
Decreased arteriolar endothelium-derived relaxing factor production during the development of genetic hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterioles; Hypertension; Male; Microcirculation; Muscles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stimulation, Chemical | 1993 |
Angiotensin II-induced endothelium-dependent relaxation of fowl aorta.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Female; Gossypol; Hydroquinones; NG-Nitroarginine Methyl Ester; Poultry; Vasoconstrictor Agents; Vasodilation | 1993 |
Restoration of normal adult penile erectile response in aged rats by long-term treatment with androgens.
Topics: Aging; Androgens; Animals; Arginine; Blotting, Western; Dihydrotestosterone; Drug Implants; Electric Stimulation; Enzyme Inhibitors; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Pressure; Rats; Rats, Inbred F344; Testosterone | 1995 |
Inhibition of feeding by a nitric oxide synthase inhibitor: effects of aging.
Topics: Aging; Animals; Enzyme Inhibitors; Feeding Behavior; Hypothalamus; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polymerase Chain Reaction; Ribonucleases; RNA, Messenger | 1996 |
Effects of N-methyl-D-aspartate and kainic acid on prolactin secretion in prepubertal female rats.
Topics: Aging; Animals; Dopamine; Enzyme Inhibitors; Female; Kainic Acid; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Serotonin; Sexual Maturation | 1996 |
Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats.
Topics: Absorptiometry, Photon; Aging; Animals; Blood Pressure; Body Weight; Bone and Bones; Bone Density; Endotoxins; Guanidines; Lumbosacral Region; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Spine | 1996 |
Impairment of vascular function is associated with an age-related increase of lipid peroxidation in rats.
Topics: Aging; Animals; Arteries; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; Lipid Peroxides; Meclofenamic Acid; Methacholine Chloride; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Arthus C. Corcoran Memorial Lecture. Influence of nitric oxide and angiotensin II on renal involvement in hypertension.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Diuretics; Endothelium, Vascular; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Sodium Chloride Symporter Inhibitors | 1997 |
Role of nitric oxide in the effect of aging on spatial memory in rats.
Topics: Aging; Animals; Brain; Brain Chemistry; Dopamine; Enzyme Inhibitors; Male; Maze Learning; Memory; NADPH Dehydrogenase; Neurons; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Serotonin; Space Perception | 1997 |
Effect of nitric oxide synthase inhibitor on age-related changes in second messenger systems and calcium channels in rats.
Topics: Aging; Animals; Autoradiography; Binding Sites; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Second Messenger Systems | 1997 |
Nitric oxide modulates ventilatory responses to hypoxia in the developing rat.
Topics: Aging; Animals; Blotting, Western; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Respiration; Solitary Nucleus | 1997 |
The increase in blood pressure induced by inhibition of nitric oxide synthase in anesthetized Wistar rats is inversely related to basal blood pressure value.
Topics: Aging; Anesthesia, General; Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Ganglionic Blockers; Hexamethonium Compounds; Male; Methylguanidine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasoconstrictor Agents | 1997 |
Alpha 1-adrenoceptor vasoconstriction in the tail artery during ageing.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Male; Microscopy, Confocal; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Tail; Vasoconstriction | 1997 |
Basal and stimulated nitric oxide in control of kidney function in the aging rat.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance; Vasoconstriction | 1997 |
Age-related changes in renal hemodynamics in female rats: role of multiple pregnancy and NO.
Topics: Aging; Animals; Blood Pressure; Enzyme Inhibitors; Female; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pregnancy, Animal; Pregnancy, Multiple; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation | 1997 |
Interactions between N-methyl-D-aspartate, nitric oxide and serotonin in the control of prolactin secretion in prepubertal male rats.
Topics: Aging; Animals; Dizocilpine Maleate; Drug Interactions; Enzyme Inhibitors; Male; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Orchiectomy; Prolactin; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Sexual Maturation; Testosterone | 1997 |
Role of endogenous NO in modulating airway contraction mediated by muscarinic receptors during development.
Topics: Acetylcholine; Aging; Animals; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Muscle Development; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Trachea; Up-Regulation | 1997 |
Increased mortality and impaired clonal deletion after staphylococcal enterotoxin B injection in old mice: relation to cytokines and nitric oxide production.
Topics: Aging; Animals; Antigens, Bacterial; Clonal Anergy; Clonal Deletion; Cytokines; Enterotoxins; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression Regulation; Immunization; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Killer Cells, Natural; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; RNA, Messenger; Shock, Septic; Staphylococcus aureus; Superantigens; Tumor Necrosis Factor-alpha | 1997 |
Ontogenesis of nitric oxide synthases in the ventilatory muscles.
Topics: Aging; Animals; Argininosuccinate Lyase; Argininosuccinate Synthase; Diaphragm; Female; Gene Expression Regulation; Immunoblotting; Immunohistochemistry; Isothiuronium; Male; Muscle Development; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transcription, Genetic | 1998 |
Effects of hypoxia and reoxygenation on nitric oxide production and cerebral blood flow in developing rat striatum.
Topics: Aging; Animals; Cerebrovascular Circulation; Corpus Striatum; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 1998 |
Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging- and dizocilpine-induced learning impairment.
Topics: Aging; Amnesia; Animals; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Enzyme Inhibitors; Learning Disabilities; Male; Maze Learning; Memory; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nootropic Agents; Pregnenolone | 1998 |
Postnatal development of nitric oxide synthase activity in fast and slow muscles of the rat.
Topics: Aging; Animals; Animals, Newborn; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Hindlimb; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1998 |
Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Kidney; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitrites; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 1998 |
Changes in the regulation by endothelium of norepinephrine response in isolated, perfused mesenteric vascular bed of rats at different ages.
Topics: Acetylcholine; Aging; Animals; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Norepinephrine; Perfusion; Potassium; Rats; Rats, Wistar; Vasoconstrictor Agents | 1998 |
Mechanism for substance P-induced relaxation of precontracted airway smooth muscle during development.
Topics: Aging; Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Muscle Development; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Substance P; Trachea | 1999 |
Nitric oxide modulation of the growth hormone-releasing activity of Hexarelin in young and old dogs.
Topics: Aging; Animals; Area Under Curve; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Erythrityl Tetranitrate; Female; Growth Hormone; Growth Substances; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Radioimmunoassay; Vasodilator Agents | 1999 |
Impact of development and chronic hypoxia on NE release from adrenergic nerves in sheep arteries.
Topics: Adrenergic Fibers; Aging; Animals; Arteries; Capsaicin; Chronic Disease; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Fetus; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Sheep | 1999 |
Age-related changes in adenosine 5'-triphosphate-induced constriction of isolated, perfused mesenteric arteries of rats.
Topics: Adenosine Triphosphate; Aging; Animals; Blood Pressure; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic P2; Vasoconstriction | 1999 |
Influence of age on inotropic response to insulin and insulin-like growth factor I in spontaneously hypertensive rats: role of nitric oxide.
Topics: Aging; Animals; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Nitric oxide mediates brain mitochondrial maturation immediately after birth.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Brain; Citrate (si)-Synthase; Cyclic GMP; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Mitochondria; Multienzyme Complexes; NAD(P)H Dehydrogenase (Quinone); NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidoreductases; Rats; Rats, Wistar; Succinate Dehydrogenase | 1999 |
Coronary vasoconstriction to endothelin-1 increases with age before and after ischaemia and reperfusion.
Topics: Aging; Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelin-1; Heart Arrest, Induced; Indomethacin; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Postoperative Period; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 1999 |
Vascular wall dysfunction in JCR:LA-cp rats: effects of age and insulin resistance.
Topics: Acetylcholine; Aging; Animals; Arteriosclerosis; Blood Glucose; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Insulin; Insulin Resistance; Male; Meclofenamic Acid; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Obesity; Phenylephrine; Rats; Rats, Mutant Strains; Triglycerides; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Influence of circadian time, ageing, and hypertension on the urinary excretion of nitric oxide metabolites in rats.
Topics: Aging; Animals; Creatinine; Diuresis; Drinking; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1999 |
Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Body Weight; Calcium; Calcium Channel Agonists; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Ventricles; Hypertension; Insulin-Like Growth Factor I; Intracellular Fluid; Kidney; Liver; Male; Microscopy, Fluorescence; Muscle Contraction; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Dysfunction | 1999 |
Aging is associated with endothelial dysfunction in the human forearm vasculature.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Brachial Artery; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Plethysmography; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2000 |
Nitric oxide and preglomerular vascular lesions in lyon spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Azo Compounds; Coloring Agents; Drug Combinations; Enzyme Inhibitors; Hydralazine; Hypertension; Kidney Glomerulus; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Vascular Diseases | 2000 |
Relaxation of vascular smooth muscle by cicletanine in aged wistar aorta under stress conditions: importance of nitric oxide.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines; Rats; Rats, Wistar; Stress, Physiological; Vasodilation | 2000 |
Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: role of cyclooxygenase-2 isoform.
Topics: Aging; Animals; Aorta, Thoracic; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Indomethacin; Isoenzymes; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; tert-Butylhydroperoxide; Time Factors; Vasoconstriction | 2000 |
Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypertension, Renal; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Punctures; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation | 2000 |
Cardiovascular effects of chronic nitric oxide synthase inhibition in genetically hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Hemodynamics; Hindlimb; Hypertension; Hypertrophy, Left Ventricular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow | 2000 |
Naltrexone-precipitated morphine withdrawal in infant rat is attenuated by acute administration of NOS inhibitors but not NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Indazoles; Infant, Newborn; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Neonatal Abstinence Syndrome; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2000 |
Role of endogenous nitric oxide in hyperoxia-induced airway hyperreactivity in maturing rats.
Topics: Aging; Animals; Bronchial Hyperreactivity; Electric Stimulation; Enzyme Inhibitors; Hyperoxia; Lung; Lung Compliance; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vagus Nerve | 2000 |
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
Topics: Acetophenones; Aging; Animals; Aorta; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Enzyme Inhibitors; Female; Hypertension; Immunohistochemistry; In Vitro Techniques; Luminescent Measurements; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Onium Compounds; Phosphoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides | 2001 |
Age-related changes in adenosine-mediated relaxation of coronary and aortic smooth muscle.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Vasodilation; Vasodilator Agents | 2001 |
Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys.
Topics: Aging; Angiotensin II; Animals; Consciousness; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2001 |
Aging alters neuronal nitric oxide release from rat mesenteric arteries: role of presynaptic beta-adrenoceptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Clenbuterol; Culture Techniques; Electric Stimulation; Male; Mesenteric Arteries; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasoconstriction; Vasodilator Agents | 2001 |
Renal hemodynamic effects of L-NAME during postnatal maturation in conscious lambs.
Topics: Aging; Animals; Animals, Newborn; Enzyme Inhibitors; Hemodynamics; NG-Nitroarginine Methyl Ester; Renal Circulation; Sheep; Vascular Resistance | 2001 |
Growth and fertility rates in the offspring of pregnant rats treated with L-omega nitro-L-arginine methyl ester (L-NAME), a nitric oxide inhibitor.
Topics: Aging; Animals; Animals, Newborn; Birth Weight; Enzyme Inhibitors; Female; Fertility; Growth; Litter Size; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values | 2002 |
Glomerular and tubular responses to N(G)-nitro-L-arginine methyl ester are age dependent in conscious lambs.
Topics: Aging; Animals; Animals, Newborn; Cardiovascular System; Diuresis; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Kidney Tubules; Natriuresis; NG-Nitroarginine Methyl Ester; Renin; Sheep; Time Factors | 2002 |
The altered balance between sympathetic nervous system and nitric oxide in salt hypertensive Dahl rats: ontogenetic and F2 hybrid studies.
Topics: Aging; Animals; Blood Pressure; Cyclic N-Oxides; Enzyme Inhibitors; Free Radical Scavengers; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentolinium Tartrate; Rats; Rats, Inbred Dahl; Sodium Chloride; Spin Labels; Superoxides; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 2002 |
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aging; Animals; Arginine; Arterioles; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Coronary Vessels; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Immunohistochemistry; In Vitro Techniques; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vasodilation; Xanthine Oxidase | 2002 |
Inhibition of nitric oxide synthase induces increased production of growth-associated protein 43 in the developing retina of the postnatal rat.
Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Enzyme Inhibitors; GAP-43 Protein; Growth Cones; Immunohistochemistry; Nerve Regeneration; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells | 2002 |
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits | 1992 |
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains | 1992 |
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar | 1992 |