nevirapine has been researched along with Stevens-Johnson Syndrome in 52 studies
Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nevirapine is used in developing countries for the treatment of HIV infection, but its use is associated with rare serious adverse reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 7.88 | A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine. ( Borgiani, P; Ciccacci, C; Ciccacci, F; Lucaroni, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Politi, C, 2018) |
| "To report a case of nevirapine-induced Stevens-Johnson syndrome (SJS) misdiagnosed as viral keratitis." | 7.74 | Nevirapine-induced Stevens-Johnson syndrome in an HIV patient. ( Jain, V; Natarajan, S; Shome, D, 2008) |
| "To draw attention to the many cases of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) related to nevirapine detected in a multinational case-control study of SJS and TEN." | 7.71 | Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. ( Bouwes-Bavinck, JN; Fagot, JP; Mockenhaupt, M; Naldi, L; Roujeau, JC; Viboud, C, 2001) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 6.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| "To investigate if pregnancy is a risk factor for SJS among HIV-infected women taking NVP-containing regimens and registered within the Medunsa National Pharmacovigilance Centre database." | 5.39 | Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012. ( Adewusi, E; Dube, N; Summers, R, 2013) |
| "Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection." | 5.31 | Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine. ( Farmer, KL; Hebert, AA; Lahart, CJ; Metry, DW, 2001) |
| "Nevirapine is used in developing countries for the treatment of HIV infection, but its use is associated with rare serious adverse reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.88 | A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine. ( Borgiani, P; Ciccacci, C; Ciccacci, F; Lucaroni, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Politi, C, 2018) |
| " We report a case of successive gynecomastia and Stevens-Johnson syndrome (SJS) respectively induced by efavirenz and nevirapine in a single patient." | 3.88 | Non-nucleoside reverse transcriptase inhibitors (NNRTIs)-induced Stevens-Johnson syndrome and gynecomastia in an HIV-infected child: A case report. ( Akakpo, AS; Bassowa, A; Dapam, AN; Kombaté, K; Laouali, AY; Mahamadou, G; Mensah, E; Mouhari-Toure, A; Pitché, P; Saka, B; Teclessou, JN, 2018) |
| "The antiretroviral nevirapine is associated with hypersensitivity reactions in 6%-10% of patients, including hepatotoxicity, maculopapular exanthema, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.85 | Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. ( Alfirevic, A; Borgiani, P; Bourgeois, S; Carr, DF; Castro, EM; Chaponda, M; Dandara, C; Deloukas, P; Haldenby, S; Heyderman, RS; Holden, A; Jones, AR; Kampira, E; Khoo, S; Lalloo, DG; Morris, AP; Munderi, P; Nelson, MR; Novelli, G; Pirmohamed, M; Rigden, DJ; Ssali, F; Takeshita, LY; van Oosterhout, JJ, 2017) |
| " We found that nevirapine use and pregnancy are independently associated with severe skin reaction." | 3.83 | Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis. ( Boulle, A; Cohen, K; de Waal, R; Lehloenya, R; Maartens, G; Stewart, A, 2016) |
| "We describe a case of nevirapine-induced Stevens-Johnson Syndrome (SJS) and fulminant hepatic failure (FHF) requiring liver transplantation." | 3.76 | Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation. ( del Rio Martin, J; Fiel, MI; Huprikar, S; Jao, J; Schiano, T; Sturdevant, M, 2010) |
| "To report a case of nevirapine-induced Stevens-Johnson syndrome (SJS) misdiagnosed as viral keratitis." | 3.74 | Nevirapine-induced Stevens-Johnson syndrome in an HIV patient. ( Jain, V; Natarajan, S; Shome, D, 2008) |
| "To draw attention to the many cases of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) related to nevirapine detected in a multinational case-control study of SJS and TEN." | 3.71 | Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. ( Bouwes-Bavinck, JN; Fagot, JP; Mockenhaupt, M; Naldi, L; Roujeau, JC; Viboud, C, 2001) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 2.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acutely occurring, unpredictable, often life-threatening reactions that are a huge challenge in clinical practice." | 2.58 | [Acute life-threatening drug reactions of the skin]. ( Mockenhaupt, M, 2018) |
| "We describe two cases of toxic epidermal necrolysis developed during an antiretroviral therapy regimen containing nevirapine." | 2.41 | Toxic epidermal necrolysis induced by nevirapine therapy: description of two cases and review of the literature. ( Cattelan, AM; Lanzafame, M; Meneghetti, F; Sasset, L; Sgarabotto, D; Trevenzoli, M, 2001) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening hypersensitivity reactions mainly caused by drugs." | 1.46 | Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis. ( Barvaliya, MJ; Hirapara, HN; Patel, TK; Tripathi, C, 2017) |
| "Steven-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe adverse drug reactions, characterized by extensive epidermal detachment and erosions of mucous membrane." | 1.42 | A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility. ( Borgiani, P; Buonomo, E; Ciccacci, C; Giardina, E; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Rufini, S; Scarcella, P, 2015) |
| "Nevirapine was the offending drug in 21/22 (95%) cases." | 1.42 | Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women. ( Knight, L; Lehloenya, RJ; Matjila, M; Muloiwa, R; Todd, G, 2015) |
| "Nevirapine (NVP) is an anti-retroviral drug used for the treatment of HIV infection, that may cause several severe adverse events, including Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)." | 1.40 | HCP5 genetic variant (RS3099844) contributes to Nevirapine-induced Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis susceptibility in a population from Mozambique. ( Borgiani, P; Ciccacci, C; Di Fusco, D; Erba, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L, 2014) |
| " SJS can occur in children at any age, with any level of immunosuppression, and can occur during the lead-in dosing period of NVP." | 1.39 | Stevens-Johnson syndrome and HIV in children in Swaziland. ( Blank, DA; Draper, HR; Dziuban, EJ; Hughey, AB; Kochelani, D; Schutze, GE; Stewart, DA, 2013) |
| "Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor, widely prescribed for type 1 human immunodeficiency virus infection." | 1.39 | Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study. ( Borgiani, P; Ciccacci, C; Di Fusco, D; Erba, F; Liotta, G; Marazzi, MC; Novelli, G; Palombi, L; Zimba, I, 2013) |
| "To investigate if pregnancy is a risk factor for SJS among HIV-infected women taking NVP-containing regimens and registered within the Medunsa National Pharmacovigilance Centre database." | 1.39 | Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012. ( Adewusi, E; Dube, N; Summers, R, 2013) |
| "The aim of this study was to measure the cumulative incidence of adverse events (AEs) related to nevirapine in patients switched from efavirenz to immediate full-dose nevirapine (FDN)." | 1.35 | Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia. ( Chhneang, V; Fernandez, M; Laureillard, D; Moeung, S; Ngeth, C; Piketty, C; Prak, N; Quillet, C; Riel, V; Song, S, 2008) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) related to a variety of medications." | 1.35 | Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. ( Bouwes Bavinck, JN; Dunant, A; Flahault, A; Halevy, S; Mockenhaupt, M; Naldi, L; Roujeau, JC; Schneck, J; Sidoroff, A; Viboud, C, 2008) |
| " Multivariate logistic regression was used to test independent association of CD4 and hepatitis C virus (HCV) infection related to the outcome of toxic effects of NVP." | 1.33 | Nevirapine toxicity in a cohort of HIV-1-infected pregnant women. ( Calvet, GA; Cruz, ML; D'Ippolito, MM; João, EC; Matos, HJ; Menezes, JA; Salgado, LA, 2006) |
| "(1) Introduce nevirapine at half the target dose, and monitor the skin, mucous membranes and liver to avoid fatal adverse effects." | 1.31 | Severe hepatic and cutaneous adverse effects with nevirapine. ( , 2000) |
| "Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection." | 1.31 | Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine. ( Farmer, KL; Hebert, AA; Lahart, CJ; Metry, DW, 2001) |
| "A 31-year-old man with the acquired immunodeficiency syndrome who developed toxic epidermal necrolysis (TEN) was successfully treated with intravenous immunoglobulin." | 1.30 | Toxic epidermal necrolysis in acquired immunodeficiency syndrome treated with intravenous gammaglobulin. ( Adelstein, S; Crotty, K; Phan, TG; Wong, RC, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (9.62) | 18.2507 |
| 2000's | 21 (40.38) | 29.6817 |
| 2010's | 26 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ciccacci, C | 5 |
| Latini, A | 1 |
| Politi, C | 2 |
| Mancinelli, S | 4 |
| Marazzi, MC | 5 |
| Novelli, G | 6 |
| Palombi, L | 5 |
| Borgiani, P | 6 |
| Hirapara, HN | 1 |
| Patel, TK | 1 |
| Barvaliya, MJ | 1 |
| Tripathi, C | 1 |
| Saka, B | 5 |
| Dzidzinyo, K | 1 |
| Akakpo, S | 3 |
| Téclessou, J | 1 |
| Nouhou Diori, A | 1 |
| Maneh, N | 1 |
| Mahamadou, G | 2 |
| Gnassingbé, W | 2 |
| Abilogun-Chokki, A | 1 |
| Mouhari-Toure, A | 4 |
| Boubacar, YA | 1 |
| Kombaté, K | 4 |
| Balo, K | 1 |
| Tchangai-Walla, K | 3 |
| Pitché, P | 4 |
| Tchetnya, X | 1 |
| Ngwasiri, CA | 1 |
| Munge, T | 1 |
| Aminde, LN | 1 |
| Mockenhaupt, M | 3 |
| Ciccacci, F | 1 |
| Lucaroni, F | 1 |
| Akakpo, AS | 1 |
| Bassowa, A | 1 |
| Dapam, AN | 1 |
| Teclessou, JN | 1 |
| Laouali, AY | 1 |
| Mensah, E | 1 |
| Bannaga, A | 1 |
| Rahama, O | 1 |
| Barlow, G | 1 |
| Patel, K | 1 |
| Panchasara, A | 1 |
| Purohit, B | 1 |
| Tripathi, CB | 1 |
| Dziuban, EJ | 1 |
| Hughey, AB | 1 |
| Stewart, DA | 1 |
| Blank, DA | 1 |
| Kochelani, D | 1 |
| Draper, HR | 1 |
| Schutze, GE | 1 |
| Di Fusco, D | 2 |
| Zimba, I | 1 |
| Erba, F | 2 |
| Liotta, G | 1 |
| Dube, N | 1 |
| Adewusi, E | 1 |
| Summers, R | 1 |
| Karlin, E | 1 |
| Phillips, E | 1 |
| Borroni, RG | 1 |
| Aho, K | 1 |
| Rufini, S | 1 |
| Buonomo, E | 1 |
| Giardina, E | 1 |
| Scarcella, P | 1 |
| Knight, L | 1 |
| Todd, G | 1 |
| Muloiwa, R | 1 |
| Matjila, M | 1 |
| Lehloenya, RJ | 1 |
| Stewart, A | 1 |
| Lehloenya, R | 1 |
| Boulle, A | 1 |
| de Waal, R | 1 |
| Maartens, G | 1 |
| Cohen, K | 1 |
| Carr, DF | 1 |
| Bourgeois, S | 1 |
| Chaponda, M | 1 |
| Takeshita, LY | 1 |
| Morris, AP | 1 |
| Castro, EM | 1 |
| Alfirevic, A | 1 |
| Jones, AR | 1 |
| Rigden, DJ | 1 |
| Haldenby, S | 1 |
| Khoo, S | 1 |
| Lalloo, DG | 1 |
| Heyderman, RS | 1 |
| Dandara, C | 1 |
| Kampira, E | 1 |
| van Oosterhout, JJ | 1 |
| Ssali, F | 1 |
| Munderi, P | 1 |
| Nelson, MR | 1 |
| Holden, A | 1 |
| Deloukas, P | 1 |
| Pirmohamed, M | 1 |
| Laureillard, D | 1 |
| Prak, N | 1 |
| Fernandez, M | 1 |
| Ngeth, C | 1 |
| Moeung, S | 1 |
| Riel, V | 1 |
| Chhneang, V | 1 |
| Song, S | 1 |
| Quillet, C | 1 |
| Piketty, C | 1 |
| Leng, K | 1 |
| Lonsdorf, A | 1 |
| Hartmann, M | 1 |
| Tebruegge, M | 1 |
| Ritz, N | 1 |
| Connell, T | 1 |
| Curtis, N | 1 |
| Oliveira, I | 1 |
| Jensen-Fangel, S | 1 |
| da Silva, D | 1 |
| Ndumba, A | 1 |
| Medina, C | 1 |
| Nanadje, A | 1 |
| Rasmussen, DN | 1 |
| Rudolf, F | 1 |
| Wejse, C | 1 |
| da Silva, ZJ | 1 |
| Sodemann, M | 1 |
| Laursen, AL | 1 |
| Chasela, CS | 1 |
| Hudgens, MG | 1 |
| Jamieson, DJ | 1 |
| Kayira, D | 1 |
| Hosseinipour, MC | 1 |
| Kourtis, AP | 1 |
| Martinson, F | 1 |
| Tegha, G | 1 |
| Knight, RJ | 1 |
| Ahmed, YI | 1 |
| Kamwendo, DD | 1 |
| Hoffman, IF | 1 |
| Ellington, SR | 1 |
| Kacheche, Z | 1 |
| Soko, A | 1 |
| Wiener, JB | 1 |
| Fiscus, SA | 1 |
| Kazembe, P | 1 |
| Mofolo, IA | 1 |
| Chigwenembe, M | 1 |
| Sichali, DS | 1 |
| van der Horst, CM | 1 |
| Jao, J | 1 |
| Sturdevant, M | 1 |
| del Rio Martin, J | 1 |
| Schiano, T | 1 |
| Fiel, MI | 1 |
| Huprikar, S | 1 |
| Hougardy, JM | 1 |
| Husson, C | 1 |
| Mackie, NE | 1 |
| Van Vooren, JP | 1 |
| Gastaldello, K | 1 |
| Nortier, JL | 1 |
| Goffard, JC | 1 |
| Barro-Traoré, F | 1 |
| Atadokpédé, FA | 1 |
| Kobangue, L | 1 |
| Niamba, PA | 1 |
| Adégbidi, H | 1 |
| Yedomon, HG | 1 |
| Traoré, A | 1 |
| Pitché, VP | 1 |
| Caumes, E | 1 |
| Bossi, P | 1 |
| Katlama, C | 1 |
| Bricaire, F | 1 |
| Hitti, J | 1 |
| Frenkel, LM | 1 |
| Stek, AM | 1 |
| Nachman, SA | 1 |
| Baker, D | 1 |
| Gonzalez-Garcia, A | 1 |
| Provisor, A | 1 |
| Thorpe, EM | 1 |
| Paul, ME | 1 |
| Foca, M | 1 |
| Gandia, J | 1 |
| Huang, S | 1 |
| Wei, LJ | 1 |
| Stevens, LM | 1 |
| Watts, DH | 1 |
| McNamara, J | 1 |
| Montero, M | 1 |
| García-Gibert, L | 1 |
| Giménez-Arnau, AM | 1 |
| Knobel, H | 1 |
| Liechty, CA | 1 |
| Solberg, P | 1 |
| Mwima, G | 1 |
| Were, W | 1 |
| Weidle, PJ | 1 |
| Mermin, J | 1 |
| João, EC | 1 |
| Calvet, GA | 1 |
| Menezes, JA | 1 |
| D'Ippolito, MM | 1 |
| Cruz, ML | 1 |
| Salgado, LA | 1 |
| Matos, HJ | 1 |
| Namayanja, GK | 1 |
| Nankya, JM | 1 |
| Byamugisha, JK | 1 |
| Ssali, FN | 1 |
| Kityo, CM | 1 |
| Rwambuya, SD | 1 |
| Mugerwa, RD | 1 |
| Mmiro, FA | 1 |
| Morrison, CS | 1 |
| Salata, RA | 1 |
| Kra, O | 1 |
| Bamba, V | 1 |
| Ehui, E | 1 |
| Tanon, A | 1 |
| Kassi, NA | 1 |
| Nzunetu, G | 1 |
| Bissagnene, E | 1 |
| Kadio, A | 1 |
| Viboud, C | 2 |
| Dunant, A | 1 |
| Naldi, L | 2 |
| Halevy, S | 1 |
| Bouwes Bavinck, JN | 1 |
| Sidoroff, A | 1 |
| Schneck, J | 1 |
| Roujeau, JC | 2 |
| Flahault, A | 1 |
| Jain, V | 1 |
| Shome, D | 1 |
| Natarajan, S | 1 |
| Oberdorfer, P | 1 |
| Washington, CH | 1 |
| Jittamala, P | 1 |
| Warren, KJ | 1 |
| Boxwell, DE | 1 |
| Kim, NY | 1 |
| Drolet, BA | 1 |
| Barner, A | 1 |
| Myers, M | 1 |
| Wetterwald, E | 1 |
| Le Cleach, L | 1 |
| Michel, C | 1 |
| David, F | 1 |
| Revuz, J | 1 |
| Descamps, V | 1 |
| Tattevin, P | 1 |
| Descamps, D | 1 |
| L'Heriteau, F | 1 |
| Schortgen, F | 1 |
| Regnier, B | 1 |
| Phan, TG | 1 |
| Wong, RC | 1 |
| Crotty, K | 1 |
| Adelstein, S | 1 |
| García Fernández, D | 1 |
| García-Patos Briones, V | 1 |
| Mollet Sánchez, J | 1 |
| Castells Rodellas, A | 1 |
| Metry, DW | 1 |
| Lahart, CJ | 1 |
| Farmer, KL | 1 |
| Hebert, AA | 1 |
| Palacios Muñoz, R | 1 |
| Santos González, J | 1 |
| Bosch García, R | 1 |
| Márquez Solero, M | 1 |
| Vera Méndez, FJ | 1 |
| Martínez Madrid, OJ | 1 |
| García Henarejos, JA | 1 |
| García Solano, J | 1 |
| Vilaplana García, R | 1 |
| Fagot, JP | 1 |
| Bouwes-Bavinck, JN | 1 |
| Cattelan, AM | 1 |
| Trevenzoli, M | 1 |
| Sasset, L | 1 |
| Sgarabotto, D | 1 |
| Lanzafame, M | 1 |
| Meneghetti, F | 1 |
| Dodi, F | 1 |
| Alessandrini, A | 1 |
| Camera, M | 1 |
| Gaffuri, L | 1 |
| Morandi, N | 1 |
| Pagano, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HIV Infection and Breastfeeding: Interventions for Maternal and Infant Health[NCT00164736] | Phase 3 | 2,369 participants (Actual) | Interventional | 2004-03-31 | Completed | ||
| Pharmacokinetics and Safety of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants[NCT04862975] | 200 participants (Anticipated) | Observational | 2024-01-08 | Not yet recruiting | |||
| Randomized Trial of Protease Inhibitor-Including vs. Protease Inhibitor-Sparing Regimens for Women Who Initiate Therapy of HIV Infection During Pregnancy[NCT00017719] | Phase 3 | 440 participants | Interventional | 2002-05-31 | Completed | ||
| Mesenchymal Stromal Cells Treatment in Lyell Syndrome: A Pilot Phase 1-2 Open Trial[NCT04711200] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for nevirapine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
[Acute life-threatening drug reactions of the skin].
Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug-R | 2018 |
Genotyping for severe drug hypersensitivity.
Topics: Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Carbamazepine; Dideoxynucleosides; Drug | 2014 |
Pharmacogenetic markers of severe cutaneous adverse drug reactions.
Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Drug E | 2014 |
[Antiretroviral-induced toxiderma in HIV-infected patients].
Topics: Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; | 2003 |
[Stevens-Johnson syndrome due to nevirapine].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Hepatitis C, Chronic; HIV-1; Humans; | 2000 |
Toxic epidermal necrolysis induced by nevirapine therapy: description of two cases and review of the literature.
Topics: Adult; Anti-HIV Agents; Communication Barriers; Female; HIV Infections; Humans; Nevirapine; Patient | 2001 |
2 trials available for nevirapine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Inf | 2004 |
44 other studies available for nevirapine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Impact of glutathione transferases genes polymorphisms in nevirapine adverse reactions: a possible role for GSTM1 in SJS/TEN susceptibility.
Topics: Anti-HIV Agents; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Glutathione Tran | 2017 |
Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Analgesics; Anti-Bacterial Agents; Anticonvulsants | 2017 |
[Factors associated with the severity of acute ocular involvement in Stevens-Johnson syndrome and toxic epidermal necrolysis in sub-Saharan Africa].
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; Child; Child, Preschool; Dermatologic Agents; E | 2018 |
Severe eye complications from toxic epidermal necrolysis following initiation of Nevirapine based HAART regimen in a child with HIV infection: a case from Cameroon.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blindness; Cameroon; Child, Preschool; HIV I | 2018 |
A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine.
Topics: Adult; Alleles; Anti-HIV Agents; Case-Control Studies; Female; Gene Frequency; Genetic Predispositio | 2018 |
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)-induced Stevens-Johnson syndrome and gynecomastia in an HIV-infected child: A case report.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitu | 2018 |
Nevirapine-induced Stevens-Johnson syndrome following HIV postexposure prophylaxis.
Topics: Adult; Diagnosis, Differential; HIV Infections; Humans; Male; Nevirapine; Post-Exposure Prophylaxis; | 2013 |
Nevirapine and/or co-trimoxazole induced Stevens Johnson syndrome in HIV infected patient--a case report.
Topics: Anti-HIV Agents; Anti-Infective Agents; Fatal Outcome; HIV Infections; Humans; Male; Middle Aged; Ne | 2013 |
Stevens-Johnson syndrome and HIV in children in Swaziland.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; C | 2013 |
Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study.
Topics: Adult; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Female; Genotype; HI | 2013 |
Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; Humans; Logistic Models; Nevir | 2013 |
HCP5 genetic variant (RS3099844) contributes to Nevirapine-induced Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis susceptibility in a population from Mozambique.
Topics: Alleles; Anti-HIV Agents; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; | 2014 |
[Recurrence of Stevens-Johnson syndrome following erroneous readministration of nevirapine].
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Medication Errors; Nevirapine; Recurrence; S | 2015 |
A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility.
Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Anti-HIV Agents; Black People; Exons; Genetic | 2015 |
Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.
Topics: Anti-HIV Agents; Female; Fetus; HIV Infections; Humans; Nevirapine; Pregnancy; Pregnancy Outcome; St | 2015 |
Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Drug Eruptions; Drug Therapy, Combination; Female; HIV | 2016 |
Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population.
Topics: Adult; Africa South of the Sahara; Aged; Anti-HIV Agents; Biomarkers; Black People; Case-Control Stu | 2017 |
Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cambodia; Cycl | 2008 |
Fatal outcome of nevirapine-associated toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; Fatal Outcome; HIV Infections; HIV-1; Humans; Male; Nevirapine; Stevens-John | 2008 |
Human immunodeficiency virus-infected boy with Stevens-Johnson syndrome caused by nevirapine.
Topics: Anti-HIV Agents; Child; HIV Infections; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 2008 |
Epidemic Stevens-Johnson syndrome in HIV patients in Guinea-Bissau: a side effect of the drug-supply policy?
Topics: Adult; Anti-HIV Agents; Epidemics; Female; Guinea-Bissau; HIV Infections; Humans; Male; Nevirapine; | 2010 |
Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hemofiltration; HIV Infections; Huma | 2010 |
[Stevens-Johnson syndrome and toxic epidermal necrolysis in a teaching hospital in Lomé, Togo: retrospective study of 89 cases].
Topics: Adult; Anti-HIV Agents; Anti-Infective Agents; Drug Therapy, Combination; Female; HIV Infections; Ho | 2010 |
Hemodiafiltration with online regeneration of ultrafiltrate for severe nevirapine intoxication in a HIV-infected patient.
Topics: Adult; Anti-HIV Agents; Hemodiafiltration; HIV Infections; Humans; Nevirapine; Stevens-Johnson Syndr | 2012 |
Stevens-Johnson syndrome and toxic epidermal necrolysis in sub-Saharan Africa: a multicentric study in four countries.
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; Aged, 80 and over; AIDS-Related Opportunistic I | 2013 |
[Toxic epidermal necrolysis associated with abacavir].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; HIV I | 2005 |
Nevirapine-induced Stevens-Johnson syndrome in a mother and son.
Topics: Adult; Anti-HIV Agents; Child; Drug Eruptions; Female; Humans; Male; Nevirapine; Reverse Transcripta | 2005 |
Nevirapine toxicity in a cohort of HIV-1-infected pregnant women.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cholestasis; Cohort Studies; Female; Hepatitis B; Hepa | 2006 |
Stevens - Johnson syndrome due to nevirapine.
Topics: Adult; Anti-HIV Agents; Female; Humans; Nevirapine; Stevens-Johnson Syndrome; Treatment Outcome | 2005 |
[First case of Stevens-Johnson syndrome in a patient treated by Triomune in Abidjan, Côte d'lvoire].
Topics: Anti-HIV Agents; Cote d'Ivoire; Drug Eruptions; Humans; Male; Middle Aged; Nevirapine; Stevens-Johns | 2007 |
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Case-Control Studies; Humans; Lamotrigine; Middle | 2008 |
Nevirapine-induced Stevens-Johnson syndrome in an HIV patient.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Conjunctival Diseases; Dry Eye Syndromes | 2008 |
Human immunodeficiency virus-infected boy with Stevens-Johnson syndrome caused by nevirapine.
Topics: Child; HIV Infections; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 2008 |
Nevirapine-associated Stevens-Johnson syndrome.
Topics: Adult; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Male; Nevirapine; Reverse Transcriptase Inhib | 1998 |
Nevirapine and rashes.
Topics: Anti-HIV Agents; Humans; Nevirapine; Stevens-Johnson Syndrome | 1998 |
Nevirapine-induced overlap stevens-johnson syndrome/toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; HIV Seropositivity; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 1999 |
HIV-1 infected patients with toxic epidermal necrolysis: an occupational risk for healthcare workers.
Topics: Aged; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Patient-to-Pr | 1999 |
Toxic epidermal necrolysis in acquired immunodeficiency syndrome treated with intravenous gammaglobulin.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Humans; Immunoglobulins, Intravenous; Ma | 1999 |
Severe hepatic and cutaneous adverse effects with nevirapine.
Topics: Chemical and Drug Induced Liver Injury; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibito | 2000 |
Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine.
Topics: Adult; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Prognosis; Ris | 2001 |
[Exanthema in a patient infected with the human immunodeficiency virus after starting antiretroviral treatment].
Topics: Adult; Anti-HIV Agents; Didanosine; Drug Eruptions; HIV Infections; Humans; Male; Nevirapine; Revers | 2000 |
[Toxic epidermal necrolysis in relation with nevirapine].
Topics: Adult; Anti-HIV Agents; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Stevens-Johnson | 2000 |
Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Drug Eruptions; Female; HIV Infections; Humans; Male; | 2001 |
Stevens-Johnson syndrome in HIV patients treated with nevirapine: two case reports.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Hepatitis C, Chronic; HIV Infections; Hu | 2002 |