nevirapine has been researched along with Plasmodium falciparum Malaria in 11 studies
Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Artemisinin-based combination therapies (ACTs) are the primary treatment for malaria." | 8.31 | Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda. ( Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K, 2023) |
| " Dihydroartemisinin-piperaquine (DPQ) is recommended for treatment of Plasmodium falciparum malaria, but its efficacy and safety has not been evaluated in HIV-infected individuals on ART, among whom drug-drug interactions are expected." | 5.30 | Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial. ( Banda, CG; Kalilani-Phiri, L; Khoo, SH; Lalloo, DG; Macuacua, S; Maculuve, S; Mallewa, J; Mukaka, M; Mwapasa, V; Piqueras, M; Sevene, E; Terlouw, DJ; Vala, A, 2019) |
| "Artemisinin-based combination therapies (ACTs) are the primary treatment for malaria." | 4.31 | Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda. ( Aweeka, F; Ehrlich, H; Freeman, T; French, J; Goodwin, J; Huang, L; Kajubi, R; Kay, K; Li, F; Mwebaza, N; Ou, J; Parikh, S; Riggs, M; Ruiz-Garcia, A; Wade, M; Wang, K, 2023) |
| " Infection with Plasmodium falciparum malaria was confirmed and treatment with quinine commenced together with amoxicillin/clavulanic acid and clarithromycin for possible respiratory infection." | 3.77 | Malaria therapy in HIV: drug interactions between nevirapine and quinine. ( Lewthwaite, P; Uriel, A, 2011) |
| "Nevirapine exposure was unchanged before and after artemether-lumefantrine administration." | 1.42 | Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral Therapy. ( Adedeji, WA; Adewole, IF; Akinyinka, OO; Aweeka, FT; Darin, KM; Fehintola, F; Huang, L; Morse, GD; Murphy, RL; Olson, A; Parikh, S; Scarsi, KK; Taiwo, BO, 2015) |
| " Our results demonstrate that the HIV PI lopinavir inhibits liver stage parasites at clinically relevant concentrations, that is, at drug levels achieved in HIV-infected patients on standard dosing regimens." | 1.39 | The effect of antiretrovirals on Plasmodium falciparum liver stages. ( Borkowsky, W; De La Vega, P; Duffy, PE; Hobbs, CV; Krzych, U; Penzak, SR; Sinnis, P; Van Vliet, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Casano, G | 1 |
| Dumètre, A | 1 |
| Pannecouque, C | 1 |
| Hutter, S | 1 |
| Azas, N | 1 |
| Robin, M | 1 |
| Kay, K | 1 |
| Goodwin, J | 1 |
| Ehrlich, H | 1 |
| Ou, J | 1 |
| Freeman, T | 1 |
| Wang, K | 1 |
| Li, F | 1 |
| Wade, M | 1 |
| French, J | 1 |
| Huang, L | 2 |
| Aweeka, F | 1 |
| Mwebaza, N | 1 |
| Kajubi, R | 1 |
| Riggs, M | 1 |
| Ruiz-Garcia, A | 1 |
| Parikh, S | 3 |
| Sevene, E | 1 |
| Banda, CG | 1 |
| Mukaka, M | 1 |
| Maculuve, S | 1 |
| Macuacua, S | 1 |
| Vala, A | 1 |
| Piqueras, M | 1 |
| Kalilani-Phiri, L | 1 |
| Mallewa, J | 1 |
| Terlouw, DJ | 1 |
| Khoo, SH | 1 |
| Lalloo, DG | 1 |
| Mwapasa, V | 1 |
| Hobbs, CV | 3 |
| Tanaka, TQ | 1 |
| Muratova, O | 1 |
| Van Vliet, J | 2 |
| Borkowsky, W | 3 |
| Williamson, KC | 1 |
| Duffy, PE | 3 |
| Chijioke-Nwauche, I | 1 |
| van Wyk, A | 1 |
| Nwauche, C | 1 |
| Beshir, KB | 1 |
| Kaur, H | 1 |
| Sutherland, CJ | 1 |
| De La Vega, P | 1 |
| Penzak, SR | 1 |
| Krzych, U | 1 |
| Sinnis, P | 1 |
| Kayentao, K | 1 |
| Guirou, EA | 1 |
| Doumbo, OK | 1 |
| Venkatesan, M | 1 |
| Plowe, CV | 1 |
| Parsons, TL | 1 |
| Hendrix, CW | 1 |
| Nyunt, MM | 1 |
| Fehintola, F | 1 |
| Olson, A | 1 |
| Adedeji, WA | 1 |
| Darin, KM | 1 |
| Morse, GD | 1 |
| Murphy, RL | 1 |
| Taiwo, BO | 1 |
| Akinyinka, OO | 1 |
| Adewole, IF | 1 |
| Aweeka, FT | 1 |
| Scarsi, KK | 1 |
| Gabriel, EE | 1 |
| Kamthunzi, P | 1 |
| Tegha, G | 1 |
| Tauzie, J | 1 |
| Petzold, E | 1 |
| Barlow-Mosha, L | 1 |
| Chi, BH | 1 |
| Li, Y | 1 |
| Ilmet, T | 1 |
| Kirmse, B | 1 |
| Neal, J | 1 |
| Deygoo, N | 1 |
| Jean Philippe, P | 1 |
| Mofenson, L | 1 |
| Prescott, W | 1 |
| Chen, J | 1 |
| Musoke, P | 1 |
| Palumbo, P | 1 |
| Naniche, D | 1 |
| Lahuerta, M | 1 |
| Bardaji, A | 1 |
| Sigauque, B | 1 |
| Romagosa, C | 1 |
| Berenguera, A | 1 |
| Mandomando, I | 1 |
| David, C | 1 |
| Sanz, S | 1 |
| Aponte, J | 1 |
| Ordi, J | 1 |
| Alonso, P | 1 |
| Menendez, C | 1 |
| Uriel, A | 1 |
| Lewthwaite, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| P1060 Substudy Comparing Differences in Malaria Parasitemia by Real Time Quantitative PCR in HIV-Infected Infants and Children on PI-Based HAART Versus NNRTI-Based HAART[NCT00719602] | Early Phase 1 | 105 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| Effect of Intermittent Preventive Treatment (IPTp) With Sulfadoxine-Pyrimethamine Plus Insecticide Treated Nets, Delivered Through Antenatal Clinics for the Prevention of Malaria in Mozambican Pregnant Women[NCT00209781] | 1,028 participants | Interventional | 2003-08-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for nevirapine and Plasmodium falciparum Malaria
8 other studies available for nevirapine and Plasmodium falciparum Malaria
| Article | Year |
|---|---|
Anti-HIV and antiplasmodial activity of original flavonoid derivatives.
Topics: Anti-HIV Agents; Antimalarials; Cell Line; Cell Survival; Flavonoids; HIV; HIV Infections; Humans; M | 2010 |
Impact of Drug Exposure on Resistance Selection Following Artemether-Lumefantrine Treatment for Malaria in Children With and Without HIV in Uganda.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Drug Comb | 2023 |
HIV treatments have malaria gametocyte killing and transmission blocking activity.
Topics: Animals; Anopheles; Anti-HIV Agents; Antimalarials; Dose-Response Relationship, Drug; HIV Protease I | 2013 |
HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infection.
Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemether, Lumefantri | 2013 |
The effect of antiretrovirals on Plasmodium falciparum liver stages.
Topics: HIV Infections; HIV Protease Inhibitors; Humans; In Vitro Techniques; Liver; Lopinavir; Malaria, Fal | 2013 |
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection.
Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Coinfection; Drug Inte | 2014 |
Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral Therapy.
Topics: Adult; Anti-HIV Agents; Antimalarials; Artemether; Artemisinins; Case-Control Studies; Coinfection; | 2015 |
Malaria therapy in HIV: drug interactions between nevirapine and quinine.
Topics: Anti-HIV Agents; Antimalarials; Atovaquone; Drug Combinations; Drug Interactions; HIV Infections; Hu | 2011 |