Page last updated: 2024-11-01

nevirapine and Liver Failure

nevirapine has been researched along with Liver Failure in 6 studies

Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)

Research Excerpts

ExcerptRelevanceReference
" In one case, a 43-year-old female health-care worker required liver transplantation after developing fulminant hepatitis and end-stage hepatic failure while taking NVP, zidovudine, and lamivudine as PEP following a needlestick injury (1)."3.71Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000. ( , 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stern, JO1
Robinson, PA1
Love, J1
Lanes, S1
Imperiale, MS1
Mayers, DL1
Cattelan, AM1
Erne, E1
Salatino, A1
Trevenzoli, M1
Carretta, G1
Meneghetti, F1
Cadrobbi, P1

Other Studies

6 other studies available for nevirapine and Liver Failure

ArticleYear
Negligence. Liver transplant patient too late to sue Viramune maker.
    AIDS policy & law, 2003, Mar-28, Volume: 18, Issue:6

    Topics: Drug Combinations; Drug Industry; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivud

2003
A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2003, Volume: 34 Suppl 1

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Trials as Topic; Cohort Studies; HIV Inf

2003
Nevirapine-related death draws attention.
    AIDS patient care and STDs, 2005, Volume: 19, Issue:3

    Topics: Clinical Trials as Topic; Fatal Outcome; Female; HIV Infections; Humans; Liver Failure; National Ins

2005
Severe hepatic failure related to nevirapine treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 29, Issue:2

    Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Liver Failure; Male; Middle Aged; Nevirapine; Revers

1999
Europe warned of side effects.
    AIDS patient care and STDs, 2000, Volume: 14, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Drug Eruptions; Europe; HIV Infections; Humans; Liver Failur

2000
Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000.
    MMWR. Morbidity and mortality weekly report, 2001, Jan-05, Volume: 49, Issue:51-52

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infectio

2001