nevirapine has been researched along with Liver Failure, Acute in 6 studies
Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation." | 7.73 | Liver transplantation for fulminant hepatitis related to nevirapine therapy. ( Antonini, T; Buyse, S; Castaing, D; Duclos-Vallée, JC; Ichai, P; Samuel, D; Sebagh, M; Vibert, E, 2006) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 6.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| "We describe a case of nevirapine-induced Stevens-Johnson Syndrome (SJS) and fulminant hepatic failure (FHF) requiring liver transplantation." | 3.76 | Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation. ( del Rio Martin, J; Fiel, MI; Huprikar, S; Jao, J; Schiano, T; Sturdevant, M, 2010) |
| " We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation." | 3.73 | Liver transplantation for fulminant hepatitis related to nevirapine therapy. ( Antonini, T; Buyse, S; Castaing, D; Duclos-Vallée, JC; Ichai, P; Samuel, D; Sebagh, M; Vibert, E, 2006) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 2.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| " One patient erroneously took double dosing of nevirapine, while the other patient did not attend the scheduled laboratory control two weeks after the initiation of nevirapine treatment." | 1.33 | [Hepatic failure due to nevirapine treatment for HIV infection]. ( Katzenstein, TL; Mens, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jao, J | 1 |
| Sturdevant, M | 1 |
| del Rio Martin, J | 1 |
| Schiano, T | 1 |
| Fiel, MI | 1 |
| Huprikar, S | 1 |
| Hitti, J | 1 |
| Frenkel, LM | 1 |
| Stek, AM | 1 |
| Nachman, SA | 1 |
| Baker, D | 1 |
| Gonzalez-Garcia, A | 1 |
| Provisor, A | 1 |
| Thorpe, EM | 1 |
| Paul, ME | 1 |
| Foca, M | 1 |
| Gandia, J | 1 |
| Huang, S | 1 |
| Wei, LJ | 1 |
| Stevens, LM | 1 |
| Watts, DH | 1 |
| McNamara, J | 1 |
| Mens, H | 1 |
| Katzenstein, TL | 1 |
| Buyse, S | 1 |
| Vibert, E | 1 |
| Sebagh, M | 1 |
| Antonini, T | 1 |
| Ichai, P | 1 |
| Castaing, D | 1 |
| Samuel, D | 1 |
| Duclos-Vallée, JC | 1 |
| Maniar, JK | 1 |
| Shah, SR | 1 |
| Verma, R | 1 |
| Kamath, R | 1 |
| Gupte, P | 1 |
| Maniar, A | 1 |
| Sha, BE | 1 |
| Proia, LA | 1 |
| Kessler, HA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Trial of Protease Inhibitor-Including vs. Protease Inhibitor-Sparing Regimens for Women Who Initiate Therapy of HIV Infection During Pregnancy[NCT00017719] | Phase 3 | 440 participants | Interventional | 2002-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for nevirapine and Liver Failure, Acute
| Article | Year |
|---|---|
Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Inf | 2004 |
5 other studies available for nevirapine and Liver Failure, Acute
| Article | Year |
|---|---|
Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hemofiltration; HIV Infections; Huma | 2010 |
[Hepatic failure due to nevirapine treatment for HIV infection].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Fatal Outcome; Female; HIV Seropositi | 2005 |
Liver transplantation for fulminant hepatitis related to nevirapine therapy.
Topics: Adult; Anti-HIV Agents; Female; Hepatitis; HIV Infections; HIV-1; Humans; Liver Failure, Acute; Live | 2006 |
Nevirapine-induced fulminant hepatitis.
Topics: Adult; Anti-Retroviral Agents; Fatal Outcome; HIV Infections; Humans; Liver Failure, Acute; Male; Ne | 2006 |
Adverse effects associated with use of nevirapine in HIV postexposure prophylaxis for 2 health care workers.
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; H | 2000 |