Page last updated: 2024-10-31

nevirapine and Hepatitis

nevirapine has been researched along with Hepatitis in 6 studies

Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"We report a case in which an HIV-positive man developed general malaise, skin rash and biochemical hepatitis within days of starting a nevirapine-based antiretroviral treatment regimen."7.80Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both? ( Helbert, MR; Higgins, SP; Komolafe, AJ; Saxon, CJ, 2014)
"To determine incidence and risk factors of nevirapine (NVP)-associated severe hepatitis that led to NVP discontinuation among HIV-infected patients with CD4 < 250 cells/microL."7.74Incidence and risk factors of nevirapine-associated severe hepatitis among HIV-infected patients with CD4 cell counts less than 250 cells/microL. ( Chaovavanich, A; Chimsuntorn, S; Chottanapund, S; Mankatitham, W; Manosuthi, W; Moolasart, V; Sittibusaya, C; Sungkanuparph, S; Tansuphaswadikul, S, 2008)
" We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation."7.73Liver transplantation for fulminant hepatitis related to nevirapine therapy. ( Antonini, T; Buyse, S; Castaing, D; Duclos-Vallée, JC; Ichai, P; Samuel, D; Sebagh, M; Vibert, E, 2006)
"At the defined period, 306 patients started a nevirapine-containing regimen, of whom eight developed an acute hepatitis (2."7.72Case series of acute hepatitis in a non-selected group of HIV-infected patients on nevirapine-containing antiretroviral treatment. ( Beijnen, JH; de Maat, MM; Mairuhu, AT; Mulder, JW; ter Heine, R; van Gorp, EC, 2003)
"We report a case in which an HIV-positive man developed general malaise, skin rash and biochemical hepatitis within days of starting a nevirapine-based antiretroviral treatment regimen."3.80Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both? ( Helbert, MR; Higgins, SP; Komolafe, AJ; Saxon, CJ, 2014)
"To determine incidence and risk factors of nevirapine (NVP)-associated severe hepatitis that led to NVP discontinuation among HIV-infected patients with CD4 < 250 cells/microL."3.74Incidence and risk factors of nevirapine-associated severe hepatitis among HIV-infected patients with CD4 cell counts less than 250 cells/microL. ( Chaovavanich, A; Chimsuntorn, S; Chottanapund, S; Mankatitham, W; Manosuthi, W; Moolasart, V; Sittibusaya, C; Sungkanuparph, S; Tansuphaswadikul, S, 2008)
" We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation."3.73Liver transplantation for fulminant hepatitis related to nevirapine therapy. ( Antonini, T; Buyse, S; Castaing, D; Duclos-Vallée, JC; Ichai, P; Samuel, D; Sebagh, M; Vibert, E, 2006)
"At the defined period, 306 patients started a nevirapine-containing regimen, of whom eight developed an acute hepatitis (2."3.72Case series of acute hepatitis in a non-selected group of HIV-infected patients on nevirapine-containing antiretroviral treatment. ( Beijnen, JH; de Maat, MM; Mairuhu, AT; Mulder, JW; ter Heine, R; van Gorp, EC, 2003)
"The aim of this study was to measure the cumulative incidence of adverse events (AEs) related to nevirapine in patients switched from efavirenz to immediate full-dose nevirapine (FDN)."1.35Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia. ( Chhneang, V; Fernandez, M; Laureillard, D; Moeung, S; Ngeth, C; Piketty, C; Prak, N; Quillet, C; Riel, V; Song, S, 2008)
"Chronic viral hepatitis is common among persons with HIV-1 infection, because of shared modes of transmission, and coinfection results in accelerated liver damage, compared with persons with chronic viral hepatitis alone."1.33Antiretroviral drug pharmacokinetics in hepatitis with hepatic dysfunction. ( Gerber, JG; Wyles, DL, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saxon, CJ1
Helbert, MR1
Komolafe, AJ1
Higgins, SP1
Laureillard, D1
Prak, N1
Fernandez, M1
Ngeth, C1
Moeung, S1
Riel, V1
Chhneang, V1
Song, S1
Quillet, C1
Piketty, C1
de Maat, MM1
ter Heine, R1
van Gorp, EC1
Mulder, JW1
Mairuhu, AT1
Beijnen, JH1
Wyles, DL1
Gerber, JG1
Buyse, S1
Vibert, E1
Sebagh, M1
Antonini, T1
Ichai, P1
Castaing, D1
Samuel, D1
Duclos-Vallée, JC1
Manosuthi, W1
Sungkanuparph, S1
Tansuphaswadikul, S1
Chottanapund, S1
Mankatitham, W1
Chimsuntorn, S1
Sittibusaya, C1
Moolasart, V1
Chaovavanich, A1

Other Studies

6 other studies available for nevirapine and Hepatitis

ArticleYear
Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both?
    International journal of STD & AIDS, 2014, Volume: 25, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Diagnosis, Differential; Exanthema; Hepatitis; HIV Inf

2014
Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia.
    HIV medicine, 2008, Volume: 9, Issue:7

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cambodia; Cycl

2008
Case series of acute hepatitis in a non-selected group of HIV-infected patients on nevirapine-containing antiretroviral treatment.
    AIDS (London, England), 2003, Oct-17, Volume: 17, Issue:15

    Topics: Acute Disease; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Drug Therapy, Combination; Female; He

2003
Antiretroviral drug pharmacokinetics in hepatitis with hepatic dysfunction.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jan-01, Volume: 40, Issue:1

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideox

2005
Liver transplantation for fulminant hepatitis related to nevirapine therapy.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2006, Volume: 12, Issue:12

    Topics: Adult; Anti-HIV Agents; Female; Hepatitis; HIV Infections; HIV-1; Humans; Liver Failure, Acute; Live

2006
Incidence and risk factors of nevirapine-associated severe hepatitis among HIV-infected patients with CD4 cell counts less than 250 cells/microL.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2008, Volume: 91, Issue:2

    Topics: Adult; Alanine Transaminase; Anti-HIV Agents; Anti-Retroviral Agents; Aspartate Aminotransferases; C

2008