Page last updated: 2024-11-01

nevirapine and EBV Infections

nevirapine has been researched along with EBV Infections in 1 studies

Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slyker, JA1
Casper, C1
Tapia, K1
Richardson, B1
Bunts, L1
Huang, ML1
Wamalwa, D1
Benki-Nugent, S1
John-Stewart, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimizing Pediatric HIV-1 Treatment, Nairobi, Kenya (0-4.5 Month Randomized Controlled Trial)[NCT00428116]140 participants (Actual)Interventional2007-09-30Terminated (stopped due to DSMB recommended termination because TI was safe but not durable.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Growth at 18 Months Post-randomization

Weight and height will be transformed to the weight-for-age Z-score (i.e., WAZ) and height-for-age Z-score (i.e., HAZ) using World Health Organization Child Growth Standards, taking into account the infant's age and gender. (NCT00428116)
Timeframe: 18 months of post-randomization follow-up

,
Interventionz-score (Median)
WAZ (z-score)HAZ (z-score)
Continued HAART-0.57-1.04
Interrupted HAART-0.17-0.78

Morbidity

severe adverse events including death, pneumonia, diarrhea, and other adverse events (NCT00428116)
Timeframe: 18 months post-randomization

,
Interventionparticipants (Number)
Severe adverse eventsPneumoniaDiarrheaDeath
Continue HAART2471
Interrupted HAART13120

Other Studies

1 other study available for nevirapine and EBV Infections

ArticleYear
Accelerated suppression of primary Epstein-Barr virus infection in HIV-infected infants initiating lopinavir/ritonavir-based versus nevirapine-based combination antiretroviral therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Volume: 58, Issue:9

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Epstein-Barr Virus Infections; HIV Infections; Humans; I

2014