nevirapine has been researched along with Drug-Induced Stevens Johnson Syndrome in 52 studies
Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nevirapine is used in developing countries for the treatment of HIV infection, but its use is associated with rare serious adverse reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 7.88 | A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine. ( Borgiani, P; Ciccacci, C; Ciccacci, F; Lucaroni, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Politi, C, 2018) |
| "To report a case of nevirapine-induced Stevens-Johnson syndrome (SJS) misdiagnosed as viral keratitis." | 7.74 | Nevirapine-induced Stevens-Johnson syndrome in an HIV patient. ( Jain, V; Natarajan, S; Shome, D, 2008) |
| "To draw attention to the many cases of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) related to nevirapine detected in a multinational case-control study of SJS and TEN." | 7.71 | Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. ( Bouwes-Bavinck, JN; Fagot, JP; Mockenhaupt, M; Naldi, L; Roujeau, JC; Viboud, C, 2001) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 6.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| "To investigate if pregnancy is a risk factor for SJS among HIV-infected women taking NVP-containing regimens and registered within the Medunsa National Pharmacovigilance Centre database." | 5.39 | Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012. ( Adewusi, E; Dube, N; Summers, R, 2013) |
| "Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection." | 5.31 | Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine. ( Farmer, KL; Hebert, AA; Lahart, CJ; Metry, DW, 2001) |
| "Nevirapine is used in developing countries for the treatment of HIV infection, but its use is associated with rare serious adverse reactions such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.88 | A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine. ( Borgiani, P; Ciccacci, C; Ciccacci, F; Lucaroni, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Politi, C, 2018) |
| " We report a case of successive gynecomastia and Stevens-Johnson syndrome (SJS) respectively induced by efavirenz and nevirapine in a single patient." | 3.88 | Non-nucleoside reverse transcriptase inhibitors (NNRTIs)-induced Stevens-Johnson syndrome and gynecomastia in an HIV-infected child: A case report. ( Akakpo, AS; Bassowa, A; Dapam, AN; Kombaté, K; Laouali, AY; Mahamadou, G; Mensah, E; Mouhari-Toure, A; Pitché, P; Saka, B; Teclessou, JN, 2018) |
| "The antiretroviral nevirapine is associated with hypersensitivity reactions in 6%-10% of patients, including hepatotoxicity, maculopapular exanthema, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)." | 3.85 | Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population. ( Alfirevic, A; Borgiani, P; Bourgeois, S; Carr, DF; Castro, EM; Chaponda, M; Dandara, C; Deloukas, P; Haldenby, S; Heyderman, RS; Holden, A; Jones, AR; Kampira, E; Khoo, S; Lalloo, DG; Morris, AP; Munderi, P; Nelson, MR; Novelli, G; Pirmohamed, M; Rigden, DJ; Ssali, F; Takeshita, LY; van Oosterhout, JJ, 2017) |
| " We found that nevirapine use and pregnancy are independently associated with severe skin reaction." | 3.83 | Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis. ( Boulle, A; Cohen, K; de Waal, R; Lehloenya, R; Maartens, G; Stewart, A, 2016) |
| "We describe a case of nevirapine-induced Stevens-Johnson Syndrome (SJS) and fulminant hepatic failure (FHF) requiring liver transplantation." | 3.76 | Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation. ( del Rio Martin, J; Fiel, MI; Huprikar, S; Jao, J; Schiano, T; Sturdevant, M, 2010) |
| "To report a case of nevirapine-induced Stevens-Johnson syndrome (SJS) misdiagnosed as viral keratitis." | 3.74 | Nevirapine-induced Stevens-Johnson syndrome in an HIV patient. ( Jain, V; Natarajan, S; Shome, D, 2008) |
| "To draw attention to the many cases of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) related to nevirapine detected in a multinational case-control study of SJS and TEN." | 3.71 | Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. ( Bouwes-Bavinck, JN; Fagot, JP; Mockenhaupt, M; Naldi, L; Roujeau, JC; Viboud, C, 2001) |
| " The one adverse event associated with nelfinavir occurred in a subject with a CD4 cell count less than 250 cells/microL." | 2.71 | Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. ( Baker, D; Foca, M; Frenkel, LM; Gandia, J; Gonzalez-Garcia, A; Hitti, J; Huang, S; McNamara, J; Nachman, SA; Paul, ME; Provisor, A; Stek, AM; Stevens, LM; Thorpe, EM; Watts, DH; Wei, LJ, 2004) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acutely occurring, unpredictable, often life-threatening reactions that are a huge challenge in clinical practice." | 2.58 | [Acute life-threatening drug reactions of the skin]. ( Mockenhaupt, M, 2018) |
| "We describe two cases of toxic epidermal necrolysis developed during an antiretroviral therapy regimen containing nevirapine." | 2.41 | Toxic epidermal necrolysis induced by nevirapine therapy: description of two cases and review of the literature. ( Cattelan, AM; Lanzafame, M; Meneghetti, F; Sasset, L; Sgarabotto, D; Trevenzoli, M, 2001) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening hypersensitivity reactions mainly caused by drugs." | 1.46 | Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis. ( Barvaliya, MJ; Hirapara, HN; Patel, TK; Tripathi, C, 2017) |
| "Steven-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe adverse drug reactions, characterized by extensive epidermal detachment and erosions of mucous membrane." | 1.42 | A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility. ( Borgiani, P; Buonomo, E; Ciccacci, C; Giardina, E; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L; Rufini, S; Scarcella, P, 2015) |
| "Nevirapine was the offending drug in 21/22 (95%) cases." | 1.42 | Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women. ( Knight, L; Lehloenya, RJ; Matjila, M; Muloiwa, R; Todd, G, 2015) |
| "Nevirapine (NVP) is an anti-retroviral drug used for the treatment of HIV infection, that may cause several severe adverse events, including Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)." | 1.40 | HCP5 genetic variant (RS3099844) contributes to Nevirapine-induced Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis susceptibility in a population from Mozambique. ( Borgiani, P; Ciccacci, C; Di Fusco, D; Erba, F; Mancinelli, S; Marazzi, MC; Novelli, G; Palombi, L, 2014) |
| " SJS can occur in children at any age, with any level of immunosuppression, and can occur during the lead-in dosing period of NVP." | 1.39 | Stevens-Johnson syndrome and HIV in children in Swaziland. ( Blank, DA; Draper, HR; Dziuban, EJ; Hughey, AB; Kochelani, D; Schutze, GE; Stewart, DA, 2013) |
| "Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor, widely prescribed for type 1 human immunodeficiency virus infection." | 1.39 | Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study. ( Borgiani, P; Ciccacci, C; Di Fusco, D; Erba, F; Liotta, G; Marazzi, MC; Novelli, G; Palombi, L; Zimba, I, 2013) |
| "To investigate if pregnancy is a risk factor for SJS among HIV-infected women taking NVP-containing regimens and registered within the Medunsa National Pharmacovigilance Centre database." | 1.39 | Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012. ( Adewusi, E; Dube, N; Summers, R, 2013) |
| "The aim of this study was to measure the cumulative incidence of adverse events (AEs) related to nevirapine in patients switched from efavirenz to immediate full-dose nevirapine (FDN)." | 1.35 | Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia. ( Chhneang, V; Fernandez, M; Laureillard, D; Moeung, S; Ngeth, C; Piketty, C; Prak, N; Quillet, C; Riel, V; Song, S, 2008) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) related to a variety of medications." | 1.35 | Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. ( Bouwes Bavinck, JN; Dunant, A; Flahault, A; Halevy, S; Mockenhaupt, M; Naldi, L; Roujeau, JC; Schneck, J; Sidoroff, A; Viboud, C, 2008) |
| " Multivariate logistic regression was used to test independent association of CD4 and hepatitis C virus (HCV) infection related to the outcome of toxic effects of NVP." | 1.33 | Nevirapine toxicity in a cohort of HIV-1-infected pregnant women. ( Calvet, GA; Cruz, ML; D'Ippolito, MM; João, EC; Matos, HJ; Menezes, JA; Salgado, LA, 2006) |
| "(1) Introduce nevirapine at half the target dose, and monitor the skin, mucous membranes and liver to avoid fatal adverse effects." | 1.31 | Severe hepatic and cutaneous adverse effects with nevirapine. ( , 2000) |
| "Nevirapine is a non-nucleoside reverse transcriptase inhibitor widely used in combination with other antiretroviral agents for the treatment of HIV infection." | 1.31 | Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine. ( Farmer, KL; Hebert, AA; Lahart, CJ; Metry, DW, 2001) |
| "A 31-year-old man with the acquired immunodeficiency syndrome who developed toxic epidermal necrolysis (TEN) was successfully treated with intravenous immunoglobulin." | 1.30 | Toxic epidermal necrolysis in acquired immunodeficiency syndrome treated with intravenous gammaglobulin. ( Adelstein, S; Crotty, K; Phan, TG; Wong, RC, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (9.62) | 18.2507 |
| 2000's | 21 (40.38) | 29.6817 |
| 2010's | 26 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ciccacci, C | 5 |
| Latini, A | 1 |
| Politi, C | 2 |
| Mancinelli, S | 4 |
| Marazzi, MC | 5 |
| Novelli, G | 6 |
| Palombi, L | 5 |
| Borgiani, P | 6 |
| Hirapara, HN | 1 |
| Patel, TK | 1 |
| Barvaliya, MJ | 1 |
| Tripathi, C | 1 |
| Saka, B | 5 |
| Dzidzinyo, K | 1 |
| Akakpo, S | 3 |
| Téclessou, J | 1 |
| Nouhou Diori, A | 1 |
| Maneh, N | 1 |
| Mahamadou, G | 2 |
| Gnassingbé, W | 2 |
| Abilogun-Chokki, A | 1 |
| Mouhari-Toure, A | 4 |
| Boubacar, YA | 1 |
| Kombaté, K | 4 |
| Balo, K | 1 |
| Tchangai-Walla, K | 3 |
| Pitché, P | 4 |
| Tchetnya, X | 1 |
| Ngwasiri, CA | 1 |
| Munge, T | 1 |
| Aminde, LN | 1 |
| Mockenhaupt, M | 3 |
| Ciccacci, F | 1 |
| Lucaroni, F | 1 |
| Akakpo, AS | 1 |
| Bassowa, A | 1 |
| Dapam, AN | 1 |
| Teclessou, JN | 1 |
| Laouali, AY | 1 |
| Mensah, E | 1 |
| Bannaga, A | 1 |
| Rahama, O | 1 |
| Barlow, G | 1 |
| Patel, K | 1 |
| Panchasara, A | 1 |
| Purohit, B | 1 |
| Tripathi, CB | 1 |
| Dziuban, EJ | 1 |
| Hughey, AB | 1 |
| Stewart, DA | 1 |
| Blank, DA | 1 |
| Kochelani, D | 1 |
| Draper, HR | 1 |
| Schutze, GE | 1 |
| Di Fusco, D | 2 |
| Zimba, I | 1 |
| Erba, F | 2 |
| Liotta, G | 1 |
| Dube, N | 1 |
| Adewusi, E | 1 |
| Summers, R | 1 |
| Karlin, E | 1 |
| Phillips, E | 1 |
| Borroni, RG | 1 |
| Aho, K | 1 |
| Rufini, S | 1 |
| Buonomo, E | 1 |
| Giardina, E | 1 |
| Scarcella, P | 1 |
| Knight, L | 1 |
| Todd, G | 1 |
| Muloiwa, R | 1 |
| Matjila, M | 1 |
| Lehloenya, RJ | 1 |
| Stewart, A | 1 |
| Lehloenya, R | 1 |
| Boulle, A | 1 |
| de Waal, R | 1 |
| Maartens, G | 1 |
| Cohen, K | 1 |
| Carr, DF | 1 |
| Bourgeois, S | 1 |
| Chaponda, M | 1 |
| Takeshita, LY | 1 |
| Morris, AP | 1 |
| Castro, EM | 1 |
| Alfirevic, A | 1 |
| Jones, AR | 1 |
| Rigden, DJ | 1 |
| Haldenby, S | 1 |
| Khoo, S | 1 |
| Lalloo, DG | 1 |
| Heyderman, RS | 1 |
| Dandara, C | 1 |
| Kampira, E | 1 |
| van Oosterhout, JJ | 1 |
| Ssali, F | 1 |
| Munderi, P | 1 |
| Nelson, MR | 1 |
| Holden, A | 1 |
| Deloukas, P | 1 |
| Pirmohamed, M | 1 |
| Laureillard, D | 1 |
| Prak, N | 1 |
| Fernandez, M | 1 |
| Ngeth, C | 1 |
| Moeung, S | 1 |
| Riel, V | 1 |
| Chhneang, V | 1 |
| Song, S | 1 |
| Quillet, C | 1 |
| Piketty, C | 1 |
| Leng, K | 1 |
| Lonsdorf, A | 1 |
| Hartmann, M | 1 |
| Tebruegge, M | 1 |
| Ritz, N | 1 |
| Connell, T | 1 |
| Curtis, N | 1 |
| Oliveira, I | 1 |
| Jensen-Fangel, S | 1 |
| da Silva, D | 1 |
| Ndumba, A | 1 |
| Medina, C | 1 |
| Nanadje, A | 1 |
| Rasmussen, DN | 1 |
| Rudolf, F | 1 |
| Wejse, C | 1 |
| da Silva, ZJ | 1 |
| Sodemann, M | 1 |
| Laursen, AL | 1 |
| Chasela, CS | 1 |
| Hudgens, MG | 1 |
| Jamieson, DJ | 1 |
| Kayira, D | 1 |
| Hosseinipour, MC | 1 |
| Kourtis, AP | 1 |
| Martinson, F | 1 |
| Tegha, G | 1 |
| Knight, RJ | 1 |
| Ahmed, YI | 1 |
| Kamwendo, DD | 1 |
| Hoffman, IF | 1 |
| Ellington, SR | 1 |
| Kacheche, Z | 1 |
| Soko, A | 1 |
| Wiener, JB | 1 |
| Fiscus, SA | 1 |
| Kazembe, P | 1 |
| Mofolo, IA | 1 |
| Chigwenembe, M | 1 |
| Sichali, DS | 1 |
| van der Horst, CM | 1 |
| Jao, J | 1 |
| Sturdevant, M | 1 |
| del Rio Martin, J | 1 |
| Schiano, T | 1 |
| Fiel, MI | 1 |
| Huprikar, S | 1 |
| Hougardy, JM | 1 |
| Husson, C | 1 |
| Mackie, NE | 1 |
| Van Vooren, JP | 1 |
| Gastaldello, K | 1 |
| Nortier, JL | 1 |
| Goffard, JC | 1 |
| Barro-Traoré, F | 1 |
| Atadokpédé, FA | 1 |
| Kobangue, L | 1 |
| Niamba, PA | 1 |
| Adégbidi, H | 1 |
| Yedomon, HG | 1 |
| Traoré, A | 1 |
| Pitché, VP | 1 |
| Caumes, E | 1 |
| Bossi, P | 1 |
| Katlama, C | 1 |
| Bricaire, F | 1 |
| Hitti, J | 1 |
| Frenkel, LM | 1 |
| Stek, AM | 1 |
| Nachman, SA | 1 |
| Baker, D | 1 |
| Gonzalez-Garcia, A | 1 |
| Provisor, A | 1 |
| Thorpe, EM | 1 |
| Paul, ME | 1 |
| Foca, M | 1 |
| Gandia, J | 1 |
| Huang, S | 1 |
| Wei, LJ | 1 |
| Stevens, LM | 1 |
| Watts, DH | 1 |
| McNamara, J | 1 |
| Montero, M | 1 |
| García-Gibert, L | 1 |
| Giménez-Arnau, AM | 1 |
| Knobel, H | 1 |
| Liechty, CA | 1 |
| Solberg, P | 1 |
| Mwima, G | 1 |
| Were, W | 1 |
| Weidle, PJ | 1 |
| Mermin, J | 1 |
| João, EC | 1 |
| Calvet, GA | 1 |
| Menezes, JA | 1 |
| D'Ippolito, MM | 1 |
| Cruz, ML | 1 |
| Salgado, LA | 1 |
| Matos, HJ | 1 |
| Namayanja, GK | 1 |
| Nankya, JM | 1 |
| Byamugisha, JK | 1 |
| Ssali, FN | 1 |
| Kityo, CM | 1 |
| Rwambuya, SD | 1 |
| Mugerwa, RD | 1 |
| Mmiro, FA | 1 |
| Morrison, CS | 1 |
| Salata, RA | 1 |
| Kra, O | 1 |
| Bamba, V | 1 |
| Ehui, E | 1 |
| Tanon, A | 1 |
| Kassi, NA | 1 |
| Nzunetu, G | 1 |
| Bissagnene, E | 1 |
| Kadio, A | 1 |
| Viboud, C | 2 |
| Dunant, A | 1 |
| Naldi, L | 2 |
| Halevy, S | 1 |
| Bouwes Bavinck, JN | 1 |
| Sidoroff, A | 1 |
| Schneck, J | 1 |
| Roujeau, JC | 2 |
| Flahault, A | 1 |
| Jain, V | 1 |
| Shome, D | 1 |
| Natarajan, S | 1 |
| Oberdorfer, P | 1 |
| Washington, CH | 1 |
| Jittamala, P | 1 |
| Warren, KJ | 1 |
| Boxwell, DE | 1 |
| Kim, NY | 1 |
| Drolet, BA | 1 |
| Barner, A | 1 |
| Myers, M | 1 |
| Wetterwald, E | 1 |
| Le Cleach, L | 1 |
| Michel, C | 1 |
| David, F | 1 |
| Revuz, J | 1 |
| Descamps, V | 1 |
| Tattevin, P | 1 |
| Descamps, D | 1 |
| L'Heriteau, F | 1 |
| Schortgen, F | 1 |
| Regnier, B | 1 |
| Phan, TG | 1 |
| Wong, RC | 1 |
| Crotty, K | 1 |
| Adelstein, S | 1 |
| García Fernández, D | 1 |
| García-Patos Briones, V | 1 |
| Mollet Sánchez, J | 1 |
| Castells Rodellas, A | 1 |
| Metry, DW | 1 |
| Lahart, CJ | 1 |
| Farmer, KL | 1 |
| Hebert, AA | 1 |
| Palacios Muñoz, R | 1 |
| Santos González, J | 1 |
| Bosch García, R | 1 |
| Márquez Solero, M | 1 |
| Vera Méndez, FJ | 1 |
| Martínez Madrid, OJ | 1 |
| García Henarejos, JA | 1 |
| García Solano, J | 1 |
| Vilaplana García, R | 1 |
| Fagot, JP | 1 |
| Bouwes-Bavinck, JN | 1 |
| Cattelan, AM | 1 |
| Trevenzoli, M | 1 |
| Sasset, L | 1 |
| Sgarabotto, D | 1 |
| Lanzafame, M | 1 |
| Meneghetti, F | 1 |
| Dodi, F | 1 |
| Alessandrini, A | 1 |
| Camera, M | 1 |
| Gaffuri, L | 1 |
| Morandi, N | 1 |
| Pagano, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HIV Infection and Breastfeeding: Interventions for Maternal and Infant Health[NCT00164736] | Phase 3 | 2,369 participants (Actual) | Interventional | 2004-03-31 | Completed | ||
| Pharmacokinetics and Safety of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants[NCT04862975] | 200 participants (Anticipated) | Observational | 2024-01-08 | Not yet recruiting | |||
| Randomized Trial of Protease Inhibitor-Including vs. Protease Inhibitor-Sparing Regimens for Women Who Initiate Therapy of HIV Infection During Pregnancy[NCT00017719] | Phase 3 | 440 participants | Interventional | 2002-05-31 | Completed | ||
| Mesenchymal Stromal Cells Treatment in Lyell Syndrome: A Pilot Phase 1-2 Open Trial[NCT04711200] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for nevirapine and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
[Acute life-threatening drug reactions of the skin].
Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug-R | 2018 |
Genotyping for severe drug hypersensitivity.
Topics: Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Carbamazepine; Dideoxynucleosides; Drug | 2014 |
Pharmacogenetic markers of severe cutaneous adverse drug reactions.
Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Drug E | 2014 |
[Antiretroviral-induced toxiderma in HIV-infected patients].
Topics: Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; | 2003 |
[Stevens-Johnson syndrome due to nevirapine].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Hepatitis C, Chronic; HIV-1; Humans; | 2000 |
Toxic epidermal necrolysis induced by nevirapine therapy: description of two cases and review of the literature.
Topics: Adult; Anti-HIV Agents; Communication Barriers; Female; HIV Infections; Humans; Nevirapine; Patient | 2001 |
2 trials available for nevirapine and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug The | 2010 |
Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Inf | 2004 |
44 other studies available for nevirapine and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
Impact of glutathione transferases genes polymorphisms in nevirapine adverse reactions: a possible role for GSTM1 in SJS/TEN susceptibility.
Topics: Anti-HIV Agents; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Glutathione Tran | 2017 |
Drug-induced Stevens-Johnson syndrome in Indian population: A multicentric retrospective analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Analgesics; Anti-Bacterial Agents; Anticonvulsants | 2017 |
[Factors associated with the severity of acute ocular involvement in Stevens-Johnson syndrome and toxic epidermal necrolysis in sub-Saharan Africa].
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; Child; Child, Preschool; Dermatologic Agents; E | 2018 |
Severe eye complications from toxic epidermal necrolysis following initiation of Nevirapine based HAART regimen in a child with HIV infection: a case from Cameroon.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blindness; Cameroon; Child, Preschool; HIV I | 2018 |
A multivariate genetic analysis confirms rs5010528 in the human leucocyte antigen-C locus as a significant contributor to Stevens-Johnson syndrome/toxic epidermal necrolysis susceptibility in a Mozambique HIV population treated with nevirapine.
Topics: Adult; Alleles; Anti-HIV Agents; Case-Control Studies; Female; Gene Frequency; Genetic Predispositio | 2018 |
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)-induced Stevens-Johnson syndrome and gynecomastia in an HIV-infected child: A case report.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitu | 2018 |
Nevirapine-induced Stevens-Johnson syndrome following HIV postexposure prophylaxis.
Topics: Adult; Diagnosis, Differential; HIV Infections; Humans; Male; Nevirapine; Post-Exposure Prophylaxis; | 2013 |
Nevirapine and/or co-trimoxazole induced Stevens Johnson syndrome in HIV infected patient--a case report.
Topics: Anti-HIV Agents; Anti-Infective Agents; Fatal Outcome; HIV Infections; Humans; Male; Middle Aged; Ne | 2013 |
Stevens-Johnson syndrome and HIV in children in Swaziland.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; C | 2013 |
Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study.
Topics: Adult; Anti-HIV Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Female; Genotype; HI | 2013 |
Risk of nevirapine-associated Stevens-Johnson syndrome among HIV-infected pregnant women: the Medunsa National Pharmacovigilance Centre, 2007 - 2012.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; Humans; Logistic Models; Nevir | 2013 |
HCP5 genetic variant (RS3099844) contributes to Nevirapine-induced Stevens Johnsons Syndrome/Toxic Epidermal Necrolysis susceptibility in a population from Mozambique.
Topics: Alleles; Anti-HIV Agents; Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; | 2014 |
[Recurrence of Stevens-Johnson syndrome following erroneous readministration of nevirapine].
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Medication Errors; Nevirapine; Recurrence; S | 2015 |
A pharmacogenetics study in Mozambican patients treated with nevirapine: full resequencing of TRAF3IP2 gene shows a novel association with SJS/TEN susceptibility.
Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Anti-HIV Agents; Black People; Exons; Genetic | 2015 |
Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Maternal and Foetal Outcomes in Twenty-Two Consecutive Pregnant HIV Infected Women.
Topics: Anti-HIV Agents; Female; Fetus; HIV Infections; Humans; Nevirapine; Pregnancy; Pregnancy Outcome; St | 2015 |
Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Drug Eruptions; Drug Therapy, Combination; Female; HIV | 2016 |
Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population.
Topics: Adult; Africa South of the Sahara; Aged; Anti-HIV Agents; Biomarkers; Black People; Case-Control Stu | 2017 |
Efavirenz replacement by immediate full-dose nevirapine is safe in HIV-1-infected patients in Cambodia.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cambodia; Cycl | 2008 |
Fatal outcome of nevirapine-associated toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; Fatal Outcome; HIV Infections; HIV-1; Humans; Male; Nevirapine; Stevens-John | 2008 |
Human immunodeficiency virus-infected boy with Stevens-Johnson syndrome caused by nevirapine.
Topics: Anti-HIV Agents; Child; HIV Infections; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 2008 |
Epidemic Stevens-Johnson syndrome in HIV patients in Guinea-Bissau: a side effect of the drug-supply policy?
Topics: Adult; Anti-HIV Agents; Epidemics; Female; Guinea-Bissau; HIV Infections; Humans; Male; Nevirapine; | 2010 |
Nevirapine-induced stevens johnson-syndrome and fulminant hepatic failure requiring liver transplantation.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hemofiltration; HIV Infections; Huma | 2010 |
[Stevens-Johnson syndrome and toxic epidermal necrolysis in a teaching hospital in Lomé, Togo: retrospective study of 89 cases].
Topics: Adult; Anti-HIV Agents; Anti-Infective Agents; Drug Therapy, Combination; Female; HIV Infections; Ho | 2010 |
Hemodiafiltration with online regeneration of ultrafiltrate for severe nevirapine intoxication in a HIV-infected patient.
Topics: Adult; Anti-HIV Agents; Hemodiafiltration; HIV Infections; Humans; Nevirapine; Stevens-Johnson Syndr | 2012 |
Stevens-Johnson syndrome and toxic epidermal necrolysis in sub-Saharan Africa: a multicentric study in four countries.
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; Aged, 80 and over; AIDS-Related Opportunistic I | 2013 |
[Toxic epidermal necrolysis associated with abacavir].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Dideoxynucleosides; HIV I | 2005 |
Nevirapine-induced Stevens-Johnson syndrome in a mother and son.
Topics: Adult; Anti-HIV Agents; Child; Drug Eruptions; Female; Humans; Male; Nevirapine; Reverse Transcripta | 2005 |
Nevirapine toxicity in a cohort of HIV-1-infected pregnant women.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cholestasis; Cohort Studies; Female; Hepatitis B; Hepa | 2006 |
Stevens - Johnson syndrome due to nevirapine.
Topics: Adult; Anti-HIV Agents; Female; Humans; Nevirapine; Stevens-Johnson Syndrome; Treatment Outcome | 2005 |
[First case of Stevens-Johnson syndrome in a patient treated by Triomune in Abidjan, Côte d'lvoire].
Topics: Anti-HIV Agents; Cote d'Ivoire; Drug Eruptions; Humans; Male; Middle Aged; Nevirapine; Stevens-Johns | 2007 |
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Case-Control Studies; Humans; Lamotrigine; Middle | 2008 |
Nevirapine-induced Stevens-Johnson syndrome in an HIV patient.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Conjunctival Diseases; Dry Eye Syndromes | 2008 |
Human immunodeficiency virus-infected boy with Stevens-Johnson syndrome caused by nevirapine.
Topics: Child; HIV Infections; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 2008 |
Nevirapine-associated Stevens-Johnson syndrome.
Topics: Adult; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Male; Nevirapine; Reverse Transcriptase Inhib | 1998 |
Nevirapine and rashes.
Topics: Anti-HIV Agents; Humans; Nevirapine; Stevens-Johnson Syndrome | 1998 |
Nevirapine-induced overlap stevens-johnson syndrome/toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; HIV Seropositivity; Humans; Male; Nevirapine; Stevens-Johnson Syndrome | 1999 |
HIV-1 infected patients with toxic epidermal necrolysis: an occupational risk for healthcare workers.
Topics: Aged; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Patient-to-Pr | 1999 |
Toxic epidermal necrolysis in acquired immunodeficiency syndrome treated with intravenous gammaglobulin.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Humans; Immunoglobulins, Intravenous; Ma | 1999 |
Severe hepatic and cutaneous adverse effects with nevirapine.
Topics: Chemical and Drug Induced Liver Injury; Humans; Nevirapine; Oxazines; Reverse Transcriptase Inhibito | 2000 |
Stevens-Johnson syndrome caused by the antiretroviral drug nevirapine.
Topics: Adult; Anti-HIV Agents; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nevirapine; Prognosis; Ris | 2001 |
[Exanthema in a patient infected with the human immunodeficiency virus after starting antiretroviral treatment].
Topics: Adult; Anti-HIV Agents; Didanosine; Drug Eruptions; HIV Infections; Humans; Male; Nevirapine; Revers | 2000 |
[Toxic epidermal necrolysis in relation with nevirapine].
Topics: Adult; Anti-HIV Agents; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Stevens-Johnson | 2000 |
Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Drug Eruptions; Female; HIV Infections; Humans; Male; | 2001 |
Stevens-Johnson syndrome in HIV patients treated with nevirapine: two case reports.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Hepatitis C, Chronic; HIV Infections; Hu | 2002 |