nevirapine has been researched along with Disease Models, Animal in 12 studies
Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Further, the addition of single-dose TDF to single-dose nevirapine (SD-NVP) during delivery following maternal ZDV use during pregnancy significantly reduces the frequency of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance." | 8.85 | Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine? ( Foster, C; Gibb, DM; Lyall, H; Olmscheid, B; Pearce, G; Zhang, S, 2009) |
| " Further, the addition of single-dose TDF to single-dose nevirapine (SD-NVP) during delivery following maternal ZDV use during pregnancy significantly reduces the frequency of nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance." | 4.85 | Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine? ( Foster, C; Gibb, DM; Lyall, H; Olmscheid, B; Pearce, G; Zhang, S, 2009) |
| "The rash is clearly immune-mediated in rats, and partial depletion of CD4(+) T cells, but not CD8(+) T cells, is protective." | 2.46 | Nevirapine hypersensitivity. ( Abdulla, D; Baban, A; Chen, J; Mannargudi, B; Popovic, M; Shenton, JM; Tharmanathan, T; Uetrecht, JP, 2010) |
| "Nevirapine has been proved to suppress tumor growth and induce differentiation in several tumor cells, but has not previously been evaluated in metastasis of thyroid cancer." | 1.51 | Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells. ( Dong, J; Liao, L; Shang, H; Wang, H; Wang, S; Yao, J; Zhao, J, 2019) |
| "Nevirapine treatment can cause a skin rash." | 1.35 | A study of the specificity of lymphocytes in nevirapine-induced skin rash. ( Chen, X; Gou, H; Mannargudi, B; Tharmanathan, T; Uetrecht, JP, 2009) |
| "Although the skin rash was less evident on rechallenge, microscopically, the cellular infiltrate was more prominent, especially surrounding the hair follicles." | 1.32 | Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat. ( Abu-Asab, MS; Shenton, JM; Teranishi, M; Uetrecht, JP; Yager, JA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Shang, H | 1 |
| Zhao, J | 1 |
| Yao, J | 1 |
| Wang, H | 1 |
| Wang, S | 1 |
| Dong, J | 1 |
| Liao, L | 1 |
| Zulu, SS | 1 |
| Abboussi, O | 1 |
| Simola, N | 1 |
| Mabandla, MV | 1 |
| Daniels, WMU | 1 |
| Mak, A | 1 |
| Uetrecht, J | 2 |
| Chen, J | 3 |
| Mannargudi, BM | 1 |
| Xu, L | 1 |
| Foster, C | 1 |
| Lyall, H | 1 |
| Olmscheid, B | 1 |
| Pearce, G | 1 |
| Zhang, S | 1 |
| Gibb, DM | 1 |
| Chen, X | 1 |
| Tharmanathan, T | 2 |
| Mannargudi, B | 2 |
| Gou, H | 1 |
| Uetrecht, JP | 4 |
| Popovic, M | 2 |
| Shenton, JM | 3 |
| Baban, A | 1 |
| Abdulla, D | 1 |
| Teranishi, M | 1 |
| Abu-Asab, MS | 1 |
| Yager, JA | 1 |
| Masson, MJ | 1 |
| Gozlan, M | 1 |
| Zuber, B | 1 |
| Böttiger, D | 1 |
| Benthin, R | 1 |
| ten Haaft, P | 1 |
| Heeney, J | 1 |
| Wahren, B | 1 |
| Oberg, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal and Infant Monitoring for Evidence of Toxicity Related to Tenofovir Exposure: The Bone and Kidney Health Substudy of the IMPAACT 1077 PROMISE Protocol (Promoting Maternal and Infant Survival Everywhere)[NCT01066858] | 1,765 participants (Actual) | Observational | 2011-03-22 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nevirapine and Disease Models, Animal
| Article | Year |
|---|---|
Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine?
Topics: Adenine; Adult; Africa South of the Sahara; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly | 2009 |
Nevirapine hypersensitivity.
Topics: Animals; Anti-HIV Agents; Biotransformation; Disease Models, Animal; Drug Hypersensitivity; Exanthem | 2010 |
10 other studies available for nevirapine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Nevirapine inhibits migration and invasion in dedifferentiated thyroid cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biopsy; Cell Line, Tumor; Cell Movement; Cell Proliferati | 2019 |
Anti-HIV drugs promote β-amyloid deposition and impair learning and memory in BALB/c mice.
Topics: Administration, Oral; AIDS Dementia Complex; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; | 2020 |
The Combination of Anti-CTLA-4 and PD1-/- Mice Unmasks the Potential of Isoniazid and Nevirapine To Cause Liver Injury.
Topics: Animals; Antibodies, Monoclonal; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fem | 2015 |
Demonstration of the metabolic pathway responsible for nevirapine-induced skin rash.
Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Exanthema | 2008 |
A study of the specificity of lymphocytes in nevirapine-induced skin rash.
Topics: Animals; Cell Proliferation; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Dr | 2009 |
Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat.
Topics: Administration, Oral; Animals; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Disease Models, Ani | 2003 |
Evidence of an immune-mediated mechanism for an idiosyncratic nevirapine-induced reaction in the female Brown Norway rat.
Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; Cyclosporine; Disease Models, Animal; Dose-R | 2005 |
Update on HIV transmission and pathogenesis.
Topics: Animals; Antiviral Agents; CD4-Positive T-Lymphocytes; Disease Models, Animal; Genes, env; HIV; HIV | 1995 |
An in vivo model for HIV resistance development.
Topics: Animals; Chimera; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; HIV Inf | 2001 |