Page last updated: 2024-11-01

nevirapine and Delayed Effects, Prenatal Exposure

nevirapine has been researched along with Delayed Effects, Prenatal Exposure in 6 studies

Nevirapine: A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.
nevirapine : A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Research Excerpts

ExcerptRelevanceReference
"However, neutropenia was no longer associated with antenatal exposure to HAART after 1 month of age."2.73Hematologic and hepatic toxicities associated with antenatal and postnatal exposure to maternal highly active antiretroviral therapy among infants. ( Bae, WH; Essex, M; Lockman, S; Onyait, K; Shapiro, RL; Smeaton, LM; Thior, I; Wester, C, 2008)
" Mice were dosed twice daily until PND 28."1.39Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u ( , 2013)
" Nevirapine is well absorbed during labor, and sufficient drug for prophylaxis against perinatal transmission crosses the placenta if an oral dose is administered to the mother at least 1 hour before delivery."1.31Antiretroviral pharmacology in pregnant women and their newborns. ( Mirochnick, M, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bae, WH1
Wester, C1
Smeaton, LM1
Shapiro, RL1
Lockman, S1
Onyait, K1
Thior, I1
Essex, M1
Temmerman, M1
Quaghebeur, A1
Mwanyumba, F1
Mandaliya, K1
Urban, MF1
Chersich, MF1
Mirochnick, M1

Trials

1 trial available for nevirapine and Delayed Effects, Prenatal Exposure

ArticleYear
Hematologic and hepatic toxicities associated with antenatal and postnatal exposure to maternal highly active antiretroviral therapy among infants.
    AIDS (London, England), 2008, Aug-20, Volume: 22, Issue:13

    Topics: Alanine Transaminase; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active

2008

Other Studies

5 other studies available for nevirapine and Delayed Effects, Prenatal Exposure

ArticleYear
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
    National Toxicology Program genetically modified model report, 2013, Issue:16

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, P

2013
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
    National Toxicology Program technical report series, 2013, Issue:569

    Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia c

2013
Mother-to-child HIV transmission in resource poor settings: how to improve coverage?
    AIDS (London, England), 2003, May-23, Volume: 17, Issue:8

    Topics: Anti-HIV Agents; Counseling; Developing Countries; Female; HIV Infections; Humans; Infant, Newborn;

2003
Dandy-Walker variant in an infant prenatally exposed to antiretroviral medication.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2007, Volume: 97, Issue:10

    Topics: Adult; Anti-Retroviral Agents; Dandy-Walker Syndrome; Female; Heart Ventricles; HIV Infections; Huma

2007
Antiretroviral pharmacology in pregnant women and their newborns.
    Annals of the New York Academy of Sciences, 2000, Volume: 918

    Topics: Administration, Oral; Anti-HIV Agents; Delivery, Obstetric; Female; HIV Infections; Humans; Infant;

2000