neurotensin--iodo-tyr(3)- and Colonic-Neoplasms

neurotensin--iodo-tyr(3)- has been researched along with Colonic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for neurotensin--iodo-tyr(3)- and Colonic-Neoplasms

Article	Year
Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29. FEBS letters, 1986, May-26, Volume: 201, Issue:1 Association of neurotensin to its receptor in HT29 cells increases the intracellular concentration of inositol phosphates. A rapid (20-30 s), transient stimulation of inositol trisphosphate (275% of the basal level) and inositol bisphosphate (420%) is first observed, followed by a slower, stable increase in inositol monophosphate (170%). Half-maximal stimulation of the three inositol phosphates was obtained with 50-100 nM neurotensin. These results indicate that neurotensin is able to regulate intracellular Ca2+ levels in HT29 cells by using inositol trisphosphate as a second messenger. Topics: Adenocarcinoma; Cell Line; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Humans; Inositol Phosphates; Kinetics; Neurotensin; Phosphatidylinositols; Receptors, Neurotensin; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate	1986

Article

Year

Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29.

FEBS letters, 1986, May-26, Volume: 201, Issue:1

Association of neurotensin to its receptor in HT29 cells increases the intracellular concentration of inositol phosphates. A rapid (20-30 s), transient stimulation of inositol trisphosphate (275% of the basal level) and inositol bisphosphate (420%) is first observed, followed by a slower, stable increase in inositol monophosphate (170%). Half-maximal stimulation of the three inositol phosphates was obtained with 50-100 nM neurotensin. These results indicate that neurotensin is able to regulate intracellular Ca2+ levels in HT29 cells by using inositol trisphosphate as a second messenger.

Topics: Adenocarcinoma; Cell Line; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Humans; Inositol Phosphates; Kinetics; Neurotensin; Phosphatidylinositols; Receptors, Neurotensin; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate

1986