neuropeptide-y has been researched along with Lymphopenia* in 2 studies
2 other study(ies) available for neuropeptide-y and Lymphopenia
Article | Year |
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The rat T-cell lymphopenia resistance gene (Lyp) maps between D4Mit6 and Npy on RN04.
Topics: Animals; Base Sequence; Chromosome Mapping; Crosses, Genetic; Diabetes Mellitus, Type 1; Genes, Recessive; Haplotypes; Lymphopenia; Molecular Sequence Data; Neuropeptide Y; Rats; Rats, Inbred BB; Rats, Inbred BN; Rats, Inbred Strains; T-Lymphocytes | 1995 |
Genetic dissection of autoimmune type I diabetes in the BB rat.
The BB rat is among the best models of insulin-dependent diabetes mellitus--with onset and pathogenesis closely resembling the human disease. One unusual feature is a severe T-cell lymphopenia, which appears to be inherited as a recessive trait controlled by a single gene, Lyp. Based on genetic analysis of several crosses, we show that development of diabetes involves at least three genes: Lyp, which is tightly linked to the neuropeptide Y (Npy) gene on chromosome 4, a gene linked to the major histocompatibility complex (MHC) on chromosome 20, and a third unmapped gene for which the Fischer rat strain carries an allele conferring resistance. Topics: Animals; Base Sequence; Chromosome Mapping; Crosses, Genetic; Diabetes Mellitus, Type 1; DNA; Female; Genes, Recessive; Genetic Linkage; Genetic Markers; Lymphopenia; Major Histocompatibility Complex; Male; Molecular Sequence Data; Neuropeptide Y; Rats; Rats, Inbred BB; Rats, Inbred F344; Rats, Inbred Lew; T-Lymphocytes | 1992 |