neuropeptide-y and Helicobacter-Infections

neuropeptide-y has been researched along with Helicobacter-Infections* in 1 studies

Other Studies

1 other study(ies) available for neuropeptide-y and Helicobacter-Infections

ArticleYear
[Neuroimmuno-modulation in gastric mucosa].
    Orvosi hetilap, 2010, Nov-21, Volume: 151, Issue:47

    Several neuropeptides were supposed to take place in the protection of gastric mucosa and play role in the development of gastritis.. To investigate morphological relationship between nerve fibres and immunocytes, to find out if these cells synthetize some neuropeptides and if there is there any co-existence with TNF-α and NFκ-B.. Immunohistochemical, confocal laser microscopic methods were used to investigate nerve fibres, immunocompetent cells in control and gastritis mucosa.. The number of neuropeptide-containing nerve fibres increased significantly. In control stomach the number of lymphocytes, plasma cells, and mast cells was low and showed no immunoreactivity for neuropeptide antibodies. However, in gastritis, some of the immunocompetent cells were immunoreactive for SP and for NPY. Some of the SP immunoreactive cells showed also positive reaction for TNF-α and NFκ-B. The distance between nerve fibres and immunocytes was 1 µm or less.. The increase of neuropeptides released from nerve fibres and immunocompetent cells can take part in neurogenic inflammation and generate chronic gastritis.

    Topics: Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Lymphocytes; Mast Cells; Microscopy, Confocal; Nerve Fibers; Neuropeptide Y; NF-kappa B; Substance P; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

2010