neuropeptide-y and Cerebral-Hemorrhage

neuropeptide-y has been researched along with Cerebral-Hemorrhage* in 2 studies

Other Studies

2 other study(ies) available for neuropeptide-y and Cerebral-Hemorrhage

Article	Year
[Changes of neuropeptide Y activity in plasma and brain tissue during intracerebral hemorrhage in rats]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2004, Volume: 16, Issue:4 To evaluate the significance of changes of neuropeptide Y (NPY) activity in plasma and brain tissue during experimental intracerebral hemorrhage (ICH).. Seventy Wistar rats were randomly divided into two groups: control group and ICH group with each group subdivided into preoperation, 0.5 hours, 6 hours, 12 hours,24 hours, 48 hours and 72 hours postoperation subgroups, respectively (n=5). The ICH was established by infusing collagenase and heparin into rat caudate. The changes of NPY in plasma and perihemotoma at preoperation, 0.5 hours, 6 hours, 12 hours, 24 hours, 48 hours and 72 hours after operation were observed, respectively. NPY was determined by radio-immunoassay. The morphologic change of brain was detected.. NPY activity in plasma and perihematoma increased synchronously after cerebral hemorrhage, and peaked at 24 hours, then began to reduce in 48 hours, it was still higher than those of preoperation at 72 hours after hemorrhage (P<0.05 or P<0.01). The correspondent pathological changes were observed in brain tissue under light microscope and electron microscope.. NPY might be involved in the pathogenesis of cerebral hemorrhage. Topics: Animals; Brain; Brain Chemistry; Cerebral Hemorrhage; Female; Immunohistochemistry; Male; Microscopy, Electron; Neuropeptide Y; Random Allocation; Rats; Rats, Wistar	2004
[Determination of neuropeptide Y concentration in the cerebrospinal fluid in patients with cerebrovascular diseases and its significance]. Zhonghua nei ke za zhi, 1991, Volume: 30, Issue:7 Concentration of neuropeptide Y (NPY) in the cerebrospinal fluid (CSF) of patients with cerebrovascular diseases was measured by using radioimmunoassay. The results showed that NPY concentration in CSF in patients with hemorrhagic cerebrovascular diseases (HCVD) was 4148 +/- 397.2 pg/ml, being significantly higher than the control level of 1083.7 +/- 245.8 pg/ml. While the NPY concentration in CSF of patients with ischemic cerebrovascular diseases (ICVD) was 2214 +/- 289.2 pg/ml, being not significantly different from the level in the control group. The effect of NPY in vasospasm after HCVD was preliminarily discussed. Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Hemorrhage; Female; Humans; Male; Middle Aged; Neuropeptide Y; Radioimmunoassay; Subarachnoid Hemorrhage	1991

Article

Year

[Changes of neuropeptide Y activity in plasma and brain tissue during intracerebral hemorrhage in rats].

Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2004, Volume: 16, Issue:4

To evaluate the significance of changes of neuropeptide Y (NPY) activity in plasma and brain tissue during experimental intracerebral hemorrhage (ICH).. Seventy Wistar rats were randomly divided into two groups: control group and ICH group with each group subdivided into preoperation, 0.5 hours, 6 hours, 12 hours,24 hours, 48 hours and 72 hours postoperation subgroups, respectively (n=5). The ICH was established by infusing collagenase and heparin into rat caudate. The changes of NPY in plasma and perihemotoma at preoperation, 0.5 hours, 6 hours, 12 hours, 24 hours, 48 hours and 72 hours after operation were observed, respectively. NPY was determined by radio-immunoassay. The morphologic change of brain was detected.. NPY activity in plasma and perihematoma increased synchronously after cerebral hemorrhage, and peaked at 24 hours, then began to reduce in 48 hours, it was still higher than those of preoperation at 72 hours after hemorrhage (P<0.05 or P<0.01). The correspondent pathological changes were observed in brain tissue under light microscope and electron microscope.. NPY might be involved in the pathogenesis of cerebral hemorrhage.

Topics: Animals; Brain; Brain Chemistry; Cerebral Hemorrhage; Female; Immunohistochemistry; Male; Microscopy, Electron; Neuropeptide Y; Random Allocation; Rats; Rats, Wistar

2004

[Determination of neuropeptide Y concentration in the cerebrospinal fluid in patients with cerebrovascular diseases and its significance].

Zhonghua nei ke za zhi, 1991, Volume: 30, Issue:7

Concentration of neuropeptide Y (NPY) in the cerebrospinal fluid (CSF) of patients with cerebrovascular diseases was measured by using radioimmunoassay. The results showed that NPY concentration in CSF in patients with hemorrhagic cerebrovascular diseases (HCVD) was 4148 +/- 397.2 pg/ml, being significantly higher than the control level of 1083.7 +/- 245.8 pg/ml. While the NPY concentration in CSF of patients with ischemic cerebrovascular diseases (ICVD) was 2214 +/- 289.2 pg/ml, being not significantly different from the level in the control group. The effect of NPY in vasospasm after HCVD was preliminarily discussed.

Topics: Aged; Aged, 80 and over; Brain Ischemia; Cerebral Hemorrhage; Female; Humans; Male; Middle Aged; Neuropeptide Y; Radioimmunoassay; Subarachnoid Hemorrhage

1991