neuropeptide-y and Ascites

neuropeptide-y has been researched along with Ascites* in 2 studies

Other Studies

2 other study(ies) available for neuropeptide-y and Ascites

Article	Year
[Significances of plasma levels of neuropeptide Y pre- and post-treatment in patients with decompensated cirrhosis and ascites]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:5 To observe changes of plasma neuropeptide Y(NPY) level in ascitic patients with decompensated cirrhosis pre- and post-treatment, there fore to understand the correlation of NPY with liver function and ascitic formation.. NPY plasma levels in 20 patients with decompensated cirrhosis and ascites were detected by radioimmunological assay.. Plasma NPY levels in patients with cirrhotic ascites were significantly lower than those in normal subjects(P < 0.01) in spite of the increases of NPY after ascites decreased (P < 0.01), which were still lower than those in normal subjects(P < 0.01).. Decreased plasma NPY levels are correlated with the severity of liver damage and may be responsible for the changes of hemodynamics and ascitic formation in patients with liver cirrhosis. Topics: Adult; Aged; Ascites; Female; Hemodynamics; Humans; Liver Cirrhosis; Male; Middle Aged; Neuropeptide Y	2003
Increased plasma levels of neuropeptide Y in hepatorenal syndrome. Journal of hepatology, 2002, Volume: 36, Issue:3 To investigate the relationship between neuropeptide Y (NPY), a potent renal vasoconstrictor peptide released upon marked stimulations of sympathetic nervous system (SNS), and renal and circulatory function in cirrhosis.. Plasma levels of NPY (radioimmunoassay) and norepinephrine and renal function parameters were determined in 17 healthy controls, nine patients with cirrhosis without ascites, and 37 patients with cirrhosis and ascites, of whom 12 had hepatorenal syndrome (HRS).. Patients with ascites showed circulating levels of NPY similar to those of patients without ascites and controls (73+/-4, +/-4 and 68+/-4 pmol/l, respectively; NS). However, patients with HRS had significantly increased levels of NPY with respect to the other groups (110+/-6 pmol/l; P<0.001). NPY levels correlated inversely with renal plasma flow and glomerular filtration rate and directly with norepinephrine. In patients with HRS (n=6) treatment with terlipressin and albumin was associated with a marked improvement in circulatory and renal function and marked suppression of NPY and norepinephrine levels.. Patients with HRS have increased levels of NPY which are related to circulatory dysfunction and SNS activation and may contribute to renal vasoconstriction. Topics: Ascites; Creatinine; Female; Glomerular Filtration Rate; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Neuropeptide Y; Norepinephrine; Renal Circulation; Vasoconstriction	2002

Article

Year

[Significances of plasma levels of neuropeptide Y pre- and post-treatment in patients with decompensated cirrhosis and ascites].

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:5

To observe changes of plasma neuropeptide Y(NPY) level in ascitic patients with decompensated cirrhosis pre- and post-treatment, there fore to understand the correlation of NPY with liver function and ascitic formation.. NPY plasma levels in 20 patients with decompensated cirrhosis and ascites were detected by radioimmunological assay.. Plasma NPY levels in patients with cirrhotic ascites were significantly lower than those in normal subjects(P < 0.01) in spite of the increases of NPY after ascites decreased (P < 0.01), which were still lower than those in normal subjects(P < 0.01).. Decreased plasma NPY levels are correlated with the severity of liver damage and may be responsible for the changes of hemodynamics and ascitic formation in patients with liver cirrhosis.

Topics: Adult; Aged; Ascites; Female; Hemodynamics; Humans; Liver Cirrhosis; Male; Middle Aged; Neuropeptide Y

2003

Increased plasma levels of neuropeptide Y in hepatorenal syndrome.

Journal of hepatology, 2002, Volume: 36, Issue:3

To investigate the relationship between neuropeptide Y (NPY), a potent renal vasoconstrictor peptide released upon marked stimulations of sympathetic nervous system (SNS), and renal and circulatory function in cirrhosis.. Plasma levels of NPY (radioimmunoassay) and norepinephrine and renal function parameters were determined in 17 healthy controls, nine patients with cirrhosis without ascites, and 37 patients with cirrhosis and ascites, of whom 12 had hepatorenal syndrome (HRS).. Patients with ascites showed circulating levels of NPY similar to those of patients without ascites and controls (73+/-4, +/-4 and 68+/-4 pmol/l, respectively; NS). However, patients with HRS had significantly increased levels of NPY with respect to the other groups (110+/-6 pmol/l; P<0.001). NPY levels correlated inversely with renal plasma flow and glomerular filtration rate and directly with norepinephrine. In patients with HRS (n=6) treatment with terlipressin and albumin was associated with a marked improvement in circulatory and renal function and marked suppression of NPY and norepinephrine levels.. Patients with HRS have increased levels of NPY which are related to circulatory dysfunction and SNS activation and may contribute to renal vasoconstriction.

Topics: Ascites; Creatinine; Female; Glomerular Filtration Rate; Hepatorenal Syndrome; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Neuropeptide Y; Norepinephrine; Renal Circulation; Vasoconstriction

2002