neurokinin-a and Urticaria

neurokinin-a has been researched along with Urticaria* in 1 studies

Trials

1 trial(s) available for neurokinin-a and Urticaria

ArticleYear
Cutaneous responses to vasoactive intestinal polypeptide in chronic idiopathic urticaria.
    Lancet (London, England), 1992, Jan-11, Volume: 339, Issue:8785

    Cutaneous wheal and flare responses to increasing concentrations of calcitonin gene-related peptide, substance P, neurokinin A, vasoactive intestinal polypeptide (VIP), compound 48/80, and phosphate-buffered saline were measured in 10 patients with chronic idiopathic urticaria and 10 healthy controls. A significant increase in VIP-induced wheal, but not flare or cutaneous blood flow, was seen in urticarial patients compared with controls (p less than 0.001). No significant differences in responses to other tested compounds were found between these groups. These data point to an increased sensitivity of microvasculature to VIP in patients with chronic idiopathic urticaria.

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Intradermal Tests; Male; Microcirculation; Middle Aged; Neurokinin A; Skin; Substance P; Urticaria; Vasoactive Intestinal Peptide

1992