netropsin has been researched along with Neoplasms in 4 studies
Netropsin: A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A lot of anticancer and antimicrobial agents derive their biological activity from their selective interaction with DNA in the minor groove and from their ability to interfere with biological processes such as enzyme catalysis, replication and transcription." | 2.61 | Carbocyclic Analogues of Distamycin and Netropsin. ( Arciszewska, K; Drozdowska, D; Pućkowska, A; Wróbel, A, 2019) |
| "Compounds were subjected to National Cancer Institute (NCI) in vitro assessment for their antitumor activity, at a single dose of 10 μM." | 1.38 | Substituted thiazoles VII. Synthesis and antitumor activity of certain 2-(substituted amino)-4-phenyl-1,3-thiazole analogs. ( Al-Omary, FA; El-Messery, SM; El-Subbagh, HI; Hassan, GS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brucoli, F | 1 |
| Natoli, A | 1 |
| Marimuthu, P | 1 |
| Borrello, MT | 1 |
| Stapleton, P | 1 |
| Gibbons, S | 1 |
| Schätzlein, A | 1 |
| Hassan, GS | 1 |
| El-Messery, SM | 1 |
| Al-Omary, FA | 1 |
| El-Subbagh, HI | 1 |
| Arciszewska, K | 1 |
| Pućkowska, A | 1 |
| Wróbel, A | 1 |
| Drozdowska, D | 1 |
| Nelson, SM | 1 |
| Ferguson, LR | 1 |
| Denny, WA | 1 |
2 reviews available for netropsin and Neoplasms
| Article | Year |
|---|---|
Carbocyclic Analogues of Distamycin and Netropsin.
Topics: Acids, Carbocyclic; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cell Proliferation; Dista | 2019 |
Non-covalent ligand/DNA interactions: minor groove binding agents.
Topics: Antineoplastic Agents; Base Sequence; Benzimidazoles; Binding Sites; Distamycins; DNA; Humans; In Vi | 2007 |
2 other studies available for netropsin and Neoplasms
| Article | Year |
|---|---|
Efficient synthesis and biological evaluation of proximicins A, B and C.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; Bacterial Infections; Cell Line, Tumo | 2012 |
Substituted thiazoles VII. Synthesis and antitumor activity of certain 2-(substituted amino)-4-phenyl-1,3-thiazole analogs.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms; Structure-Activity R | 2012 |