netropsin has been researched along with Adult Premature Aging Syndrome in 2 studies
Netropsin: A basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We show here that antisense suppression of WRN in two human glioma cell lines reproduces hallmarks of the drug cytotoxicity profile of WS cells, namely, hypersensitivity to 4-nitroquinoline 1-oxide, camptothecin and hydroxyurea." | 3.72 | The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. ( Blank, A; Bobola, MS; D Kolstoe, D; Gold, B; Loeb, LA; Meade, EH; Rabinovitch, PS; Silber, JR; Varadarajan, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blank, A | 1 |
| Bobola, MS | 1 |
| Gold, B | 1 |
| Varadarajan, S | 1 |
| D Kolstoe, D | 1 |
| Meade, EH | 1 |
| Rabinovitch, PS | 1 |
| Loeb, LA | 1 |
| Silber, JR | 1 |
| Brosh, RM | 1 |
| Karow, JK | 1 |
| White, EJ | 1 |
| Shaw, ND | 1 |
| Hickson, ID | 1 |
| Bohr, VA | 1 |
2 other studies available for netropsin and Adult Premature Aging Syndrome
| Article | Year |
|---|---|
The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Alkylating Agents; Antineoplastic Agents; Apoptosis; Camptothecin | 2004 |
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs.
Topics: Adenosine Triphosphatases; Bloom Syndrome; Distamycins; DNA Helicases; Enzyme Inhibitors; Exodeoxyri | 2000 |