netilmicin has been researched along with Bronchitis* in 4 studies
3 trial(s) available for netilmicin and Bronchitis
Article | Year |
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[Clinical, bactericidal and pharmacological evaluation of the effects of netromycin].
To analyze clinical, bactericidal effectiveness and pharmacokinetics of wide-spectrum antibiotic netromycin (NM).. The trial entered 29 patients: 21 with bronchopulmonary diseases (pneumonia and chronic bronchitis), 5 with exacerbation of chronic pyelonephritis, 2 with infectious endocarditis and 1 with peritonsillar abscess.. Microbiologically, most of the agents (80.36%) showed sensitivity to NM. Pharmacologically, NM persisted long in blood serum and sputum irrespective of the administration mode. Positive clinical dynamics after NM treatment was achieved in all the patients but one who had a peritonsillar abscess.. NM is highly active against both gram-positive and gram-negative flora. Side effects are minimal. Topics: Adult; Aged; Bacteria; Bronchitis; Endocarditis, Bacterial; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Netilmicin; Peritonsillar Abscess; Pneumonia; Pyelonephritis | 1999 |
[Clinical studies on the time-difference combination therapy with netilmicin and minocycline in methicillin-resistant Staphylococcus aureus infections].
Twenty-eight patients with methicillin-resistant Staphylococcus aureus (MRSA) infections were clinically studied for the effectiveness of the time-difference combination use of netilmicin (NTL) and minocycline (MINO). The patients were treated with NTL 100 mg and two hours later, with MINO 100 mg intravenously, twice daily, in the morning and evening for 14 days. Of 26 patients, MRSA was eradicated in 16 (61.5%), decreased in one, and unchanged in nine. Superinfections occurred with Serratia marcescens and Pseudomonas aeruginosa in two patients. The clinical efficacies were assessed in two patients with septicemia, 16 with pneumonia, and eight with chronic bronchitis. The obtained results were excellent in four patients, good in 15, fair in six, and poor in one patient. The rate of effectiveness was 73.1% (19/26). The overall clinical effectiveness judged by the committee was good in 19, fair in five, and poor in two patients. The efficacy rate was also 73.1% (19/26). Coagulase type II of MRSA was found in 23 patients, and coagulase type III in three patients, with overall clinical efficacy rates of 73.9% (17/23) and 66.7% (2/3), respectively. A side effect of eruption was observed in one patient, and its incidence was 3.6% (1/28). Abnormal laboratory test results were observed in 16 patients (57.1%), including abnormal liver function in 14 patients, abnormal kidney function in three, and increased eosinophils in three. Laboratory abnormalities occurred twelve of 16 bedridden patients, and this rate was higher than that in non bedridden patients. However, these abnormalities were all mild, transient, and immediately recovered after the treatment. In conclusion, the time-difference combination therapy using NTL and MINO was effective in the treatment of MRSA infections. Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchitis; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Japan; Male; Methicillin Resistance; Middle Aged; Minocycline; Netilmicin; Pneumonia, Staphylococcal; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Superinfection | 1994 |
[Comparative test of the effectiveness of Netilmicin and Sisomicin on respiratory tract infection by double blind method].
Topics: Adult; Aged; Bronchitis; Clinical Trials as Topic; Double-Blind Method; Female; Gentamicins; Humans; Male; Middle Aged; Netilmicin; Pneumonia; Respiratory Tract Infections; Sisomicin | 1983 |
1 other study(ies) available for netilmicin and Bronchitis
Article | Year |
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[Clinico-bacteriological efficacy, pharmacokinetics and tolerability of netilmicin administered in a daily single dose in bronchopulmonary infections].
Topics: Aged; Bacteria; Bronchitis; Bronchopneumonia; Drug Evaluation; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Netilmicin; Time Factors | 1988 |