nephrin has been researched along with Diarrhea* in 1 studies
1 trial(s) available for nephrin and Diarrhea
Article | Year |
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Urinary podocyte mRNA excretion in children with D+HUS: a potential marker of long-term outcome.
Diarrhea-associated hemolytic uremic syndrome (D+HUS) causes acute renal failure and may lead to podocyte loss. Objective. To determine if the urinary mRNA excretion of podocyte proteins is detectable in children with D+HUS and if it is a biomarker of a poor long-term outcome.. Patients were randomly selected from participants in the SYNSORB Pk trial. Urine samples were collected daily during the first week of hospitalization. Specimens were also obtained in healthy volunteers. Synaptopodin and nephrin mRNA levels were measured using real-time PCR.. Fifteen children, aged 4.9+/-2.8 years, were studied. Patients were categorized based on urinary mRNA levels into normal (marker:GAPDH Topics: Adolescent; Biomarkers; Child; Child, Preschool; Diarrhea; Hemolytic-Uremic Syndrome; Humans; Infant; Membrane Proteins; Microfilament Proteins; Organosilicon Compounds; Podocytes; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trisaccharides | 2006 |