Page last updated: 2024-10-31

neostigmine and Vomiting

neostigmine has been researched along with Vomiting in 19 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."9.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)
"We performed this randomized, double-blind, placebo-controlled study to determine whether reversal of neuromuscular block with neostigmine increases the incidence and severity of postoperative nausea and vomiting (PONV)."9.08Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. ( Halonen, P; Hovorka, J; Korttila, K; Nelskylä, K; Paatero, H; Sarvela, J; Soikkeli, A; Yli-Hankala, A, 1997)
"Neostigmine/atropine was effective in treating PDPH after only 2 doses."6.87Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial. ( Abdelaal Ahmed Mahmoud, A; Abdelhaq, M; Cusack, B; Elayashy, M; Elemady, MF; Elkady, HW; Hosny, H; Hussein, HA; Kamal, AM; Mahmoud, HE; Mansour, AZ; Yassin, HM, 2018)
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."5.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)
"We performed this randomized, double-blind, placebo-controlled study to determine whether reversal of neuromuscular block with neostigmine increases the incidence and severity of postoperative nausea and vomiting (PONV)."5.08Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. ( Halonen, P; Hovorka, J; Korttila, K; Nelskylä, K; Paatero, H; Sarvela, J; Soikkeli, A; Yli-Hankala, A, 1997)
" morphine 100 microg, but with a high incidence of nausea and vomiting."5.08The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia. ( Chin, YJ; Chung, CJ; Kim, JS; Park, HS, 1998)
"Neostigmine/atropine was effective in treating PDPH after only 2 doses."2.87Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial. ( Abdelaal Ahmed Mahmoud, A; Abdelhaq, M; Cusack, B; Elayashy, M; Elemady, MF; Elkady, HW; Hosny, H; Hussein, HA; Kamal, AM; Mahmoud, HE; Mansour, AZ; Yassin, HM, 2018)
" Opiate dosage consumed was also recorded as a primary outcome during the first 24 h following surgery."2.73Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study. ( Hamidi, S; Khan, ZH; Majedi, H; Miri, M; Nourijelyani, K, 2008)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's9 (47.37)18.2507
2000's1 (5.26)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdelaal Ahmed Mahmoud, A1
Mansour, AZ1
Yassin, HM1
Hussein, HA1
Kamal, AM1
Elayashy, M1
Elemady, MF1
Elkady, HW1
Mahmoud, HE1
Cusack, B1
Hosny, H1
Abdelhaq, M1
Bawaskar, HS1
Bawaskar, PH2
Khan, ZH1
Hamidi, S1
Miri, M1
Majedi, H1
Nourijelyani, K1
PERRICELLI, F1
WEBSTER, JL1
PICKERING, D1
Boeke, AJ2
Watcha, MF2
Safavi, FZ1
McCulloch, DA1
Tan, TS1
White, PF2
de Lange, JJ1
van Druenen, B1
Langemeijer, JJ1
Huang, CH1
Wang, MJ1
Susetio, L1
Cherng, YG1
Shi, JJ1
Chen, YA1
Chiu, WH1
Lauretti, GR1
Azevedo, VM1
Clarke, PM1
Hovorka, J1
Korttila, K1
Nelskylä, K1
Soikkeli, A1
Sarvela, J1
Paatero, H1
Halonen, P1
Yli-Hankala, A1
Chung, CJ1
Kim, JS1
Park, HS1
Chin, YJ1
King, MJ1
Milazkiewicz, R1
Carli, F1
Deacock, AR1
Weisbrodt, NW1
Christensen, J1
Guttmann, L1
Walsh, JJ1
Maldonado, JE1
Gregg, JA1
Green, PA1
Brown, AL1
Friis, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neostigmine and Atropine for the Treatment of Post Dural Puncture Headache After Known Dural Puncture With a Tuohy Needle: A Pilot Study[NCT05116930]Phase 218 participants (Anticipated)Interventional2021-11-19Recruiting
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache: Prospective, Randomized, Controlled, Triple-blinded Trial[NCT04905953]Phase 2/Phase 3274 participants (Anticipated)Interventional2021-02-01Recruiting
Evaluation of Intrathecal Neostigmine as an Adjuvant to Bupivacaine in Ameliorating Post-Dural Puncture Headache in Elective Caesarian Section: A Prospective Randomized Controlled Clinical Trial[NCT05289323]Phase 4722 participants (Actual)Interventional2022-04-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

10 trials available for neostigmine and Vomiting

ArticleYear
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:6

    Topics: Adult; Anesthesia, General; Anesthesia, Spinal; Atropine; Blood Patch, Epidural; Blood-Brain Barrier

2018
Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study.
    Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:6

    Topics: Adult; Analgesics, Opioid; Cholinesterase Inhibitors; Diskectomy; Double-Blind Method; Female; Human

2008
Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Anesthesia Recovery Period; Atropine; Child; Double-Blind Method; Edrophonium; Glycopyrrolate; Human

1995
Effect of antagonizing residual neuromuscular block by neostigmine and atropine on postoperative vomiting.
    British journal of anaesthesia, 1994, Volume: 72, Issue:6

    Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, General; Atropine; Female; Huma

1994
Comparison of the combined effects of atropine and neostigmine with atropine and edrophonium on the occurrence of postoperative nausea and vomiting.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1993, Volume: 31, Issue:2

    Topics: Adult; Atropine; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Edrophoniu

1993
Intrathecal neostigmine.
    Anaesthesia, 1997, Volume: 52, Issue:10

    Topics: Cholinesterase Inhibitors; Humans; Nausea; Neostigmine; Pain, Postoperative; Vomiting

1997
Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Adult; Aged; Anesthesia, General; Double-Blind Method; Female; Humans; Hysterectomy; Isoquinolines;

1997
The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Hu

1998
Influence of neostigmine on postoperative vomiting.
    British journal of anaesthesia, 1988, Volume: 61, Issue:4

    Topics: Aged; Atropine; Hip Prosthesis; Humans; Knee Prosthesis; Nausea; Neostigmine; Postoperative Complica

1988
[Effect of Primperan versus neostigmine on the postoperative gastrointestinal tract].
    Ugeskrift for laeger, 1971, Jan-22, Volume: 133, Issue:3

    Topics: Amides; Benzoates; Defecation; Digestive System; Female; Genital Diseases, Female; Humans; Male; Met

1971

Other Studies

9 other studies available for neostigmine and Vomiting

ArticleYear
Premonitory signs and symptoms of envenoming by common krait (Bungarus caeruleus).
    Tropical doctor, 2014, Volume: 44, Issue:2

    Topics: Adult; Animals; Atropine; Autonomic Nervous System Diseases; Bulbar Palsy, Progressive; Bungarus; Ch

2014
[Treatment of hyperemesis pregnancy with vitamin B6 and prostigmine].
    Hospital (Rio de Janeiro, Brazil), 1954, Volume: 45, Issue:6

    Topics: Female; Humans; Hyperemesis Gravidarum; Neostigmine; Pregnancy; Pregnancy Complications; Vitamin B 6

1954
ACUTE MUSHROOM POISONING: TREATMENT WITH CURARE AND INTERMITTENT POSITIVE PRESSURE RESPIRATION.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Agaricales; Atropine; Child; Curare; Drug Therapy; Edema; Gastric Lavage; Mushroom Poisoning; Neosti

1964
Does neostigmine cause nausea and vomiting?
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Humans; Nausea; Neostigmine; Postoperative Complications; Vomiting

1995
Intravenous ketamine or fentanyl prolongs postoperative analgesia after intrathecal neostigmine.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Dissociative; Anesthetics, Intraveno

1996
Reversal of neuromuscular blockade.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Female; Humans; Hysterectomy; Nausea; Neostigmine; Neuromuscular Blockade; Postoperative Complicatio

1998
Electrical activity of the cat duodenum in fasting and vomiting.
    Gastroenterology, 1972, Volume: 63, Issue:6

    Topics: Action Potentials; Animals; Atropine; Cats; Duodenum; Electromyography; Food Deprivation; Jejunum; M

1972
Prostigmin assessment test of fertility in spinal man.
    Paraplegia, 1971, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Cauda Equina; Cell Count; Ejaculation; Erectile Dysfunction; Fert

1971
Chronic idiopathic intestinal pseudo-obstruction.
    The American journal of medicine, 1970, Volume: 49, Issue:2

    Topics: Abdomen, Acute; Acidosis; Adolescent; Adult; Anemia; Celiac Disease; Chronic Disease; Deficiency Dis

1970