neostigmine has been researched along with Spinal Cord Injuries in 22 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Severe constipation is a debilitating concomitant of complete traumatic thoracic spinal cord injury." | 1.27 | Colonic dysfunction in patients with thoracic spinal cord injury. ( Bradley, WE; Downey, N; Glick, ME; Haldeman, S; Hoehler, F; Meshkinpour, H, 1984) |
| "Thus persons with spinal cord injuries have higher basal colonic myoelectric activity than normals but lack a demonstrable gastrocolic reflex." | 1.27 | Colonic myoelectric activity in persons with spinal cord injury. ( Aaronson, MJ; Burakoff, R; Freed, MM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silver, JR | 1 |
| Weiner, MF | 1 |
| Korsten, MA | 5 |
| Lyons, BL | 2 |
| Radulovic, M | 3 |
| Cummings, TM | 1 |
| Sikka, G | 1 |
| Singh, K | 1 |
| Hobson, JC | 1 |
| Sabiev, A | 1 |
| Spungen, AM | 4 |
| Bauman, WA | 5 |
| Rosman, AS | 4 |
| Hunt, K | 1 |
| Galea, MD | 1 |
| Kornfeld, SD | 1 |
| Yen, C | 1 |
| BASHCHANSKAIA, ML | 1 |
| Ng, A | 1 |
| Cavusoglu, E | 1 |
| Wecht, J | 1 |
| Singal, AK | 1 |
| Chaparala, G | 1 |
| Monga, A | 1 |
| Chapelle, PA | 1 |
| Colbeau-Justin, P | 1 |
| Durand, J | 1 |
| Richard, F | 1 |
| Glick, ME | 1 |
| Meshkinpour, H | 1 |
| Haldeman, S | 1 |
| Hoehler, F | 1 |
| Downey, N | 1 |
| Bradley, WE | 1 |
| Amelar, RD | 1 |
| Dubin, L | 1 |
| Witt, MA | 1 |
| Grantmyre, JE | 1 |
| Feringa, ER | 1 |
| Kowalski, TF | 1 |
| Vahlsing, HL | 1 |
| Frye, RA | 1 |
| Sønksen, J | 1 |
| Biering-Sørensen, F | 1 |
| Ver Voort, SM | 1 |
| Comarr, AE | 1 |
| Aaronson, MJ | 1 |
| Freed, MM | 1 |
| Burakoff, R | 1 |
| Teuber, HL | 1 |
| Griffith, ER | 1 |
| Tomko, MA | 1 |
| Timms, RJ | 1 |
| Rossier, AB | 2 |
| Ziegler, WH | 2 |
| Duchosal, PW | 2 |
| Meylan, J | 2 |
| Guttmann, L | 1 |
| Walsh, JJ | 1 |
| Miyazaki, K | 1 |
7 reviews available for neostigmine and Spinal Cord Injuries
| Article | Year |
|---|---|
The history of the use of intrathecal prostigmine to achieve fertility in men with spinal cord injuries.
Topics: Cholinesterase Inhibitors; History, 20th Century; Humans; Infertility, Male; Male; Neostigmine; Spin | 2019 |
Recent concepts in the management of bowel problems after spinal cord injury.
Topics: Colon; Colonic Diseases, Functional; Constipation; Drug Therapy, Combination; Glycopyrrolate; Humans | 2006 |
Ejaculatory failure.
Topics: Combined Modality Therapy; Diabetes Complications; Ejaculation; Electric Stimulation Therapy; Humans | 1993 |
Fertility in men with spinal cord or cauda equina lesions.
Topics: Adult; Cauda Equina; Coitus; Ejaculation; Electric Stimulation Therapy; Female; Humans; Infant, Newb | 1992 |
Ejaculatory stimulation in spinal-cord injured men.
Topics: Ejaculation; Electric Stimulation Therapy; Humans; Insemination, Artificial; Male; Neostigmine; Phys | 1987 |
Sexuality and fertility among spinal cord and/or cauda equina injuries.
Topics: Biopsy; Cauda Equina; Coitus; Ejaculation; Electric Stimulation; Female; Fertility; Humans; Insemina | 1985 |
Sexual function in spinal cord-injured patients: a review.
Topics: Coitus; Ejaculation; Female; Fertility; Humans; Insemination, Artificial; Libido; Male; Neostigmine; | 1973 |
4 trials available for neostigmine and Spinal Cord Injuries
| Article | Year |
|---|---|
Delivery of neostigmine and glycopyrrolate by iontophoresis: a nonrandomized study in individuals with spinal cord injury.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relat | 2018 |
Neostigmine Administered With MoviPrep Improves Bowel Preparation for Elective Colonoscopy in Patients With Spinal Cord Injury: A Randomized Study.
Topics: Aged; Cathartics; Cholinesterase Inhibitors; Colonoscopy; Glycopyrrolate; Humans; Middle Aged; Neost | 2015 |
Infusion of neostigmine-glycopyrrolate for bowel evacuation in persons with spinal cord injury.
Topics: Adult; Airway Resistance; Cholinergic Antagonists; Defecation; Glycopyrrolate; Heart Rate; Humans; I | 2005 |
Intramuscular neostigmine and glycopyrrolate safely accelerated bowel evacuation in patients with spinal cord injury and defecatory disorders.
Topics: Adult; Blood Pressure; Constipation; Cross-Over Studies; Defecation; Double-Blind Method; Glycopyrro | 2008 |
11 other studies available for neostigmine and Spinal Cord Injuries
| Article | Year |
|---|---|
[Use of proserin in combination with balneotherapy in sequelae of injuries of the spine and spinal cord].
Topics: Balneology; Humans; Neostigmine; Spinal Cord Injuries; Spinal Injuries; Spine | 1954 |
[Ejaculation problems in traumatic paraplegia ].
Topics: Adolescent; Adult; Ejaculation; Female; Humans; Male; Middle Aged; Neostigmine; Paraplegia; Semen; S | 1982 |
Colonic dysfunction in patients with thoracic spinal cord injury.
Topics: Adult; Colon; Constipation; Evoked Potentials, Somatosensory; Humans; Male; Middle Aged; Motor Neuro | 1984 |
Sexual function and fertility in paraplegic males.
Topics: Coitus; Ejaculation; Electric Stimulation; Female; Fertility; Humans; Insemination, Artificial, Homo | 1982 |
Enzyme treatment of spinal cord transected rats.
Topics: Animals; Drug Combinations; Female; Hyaluronoglucosaminidase; Neostigmine; Pancreatic Elastase; Pyro | 1979 |
Colonic myoelectric activity in persons with spinal cord injury.
Topics: Adult; Colon; Defecation; Eating; Electromyography; Female; Gastrointestinal Motility; Humans; Male; | 1985 |
Functional recovery after lesions of the nervous system. II. Recovery of function after lesions of the central nervous system: history and prospects.
Topics: Age Factors; Amphetamine; Anesthesia, General; Animals; Aphasia; Brain Injuries; Brain Mapping; Cats | 1974 |
Sexual function and dysreflexia.
Topics: Accidents, Traffic; Adult; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Dysautonomia, Famil | 1971 |
Prostigmin assessment test of fertility in spinal man.
Topics: Adolescent; Adult; Blood Pressure; Cauda Equina; Cell Count; Ejaculation; Erectile Dysfunction; Fert | 1971 |
[Sexual function, autonomic dysreflexia and catecholamines in traumatic medullary lesions].
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure Determination; Catecholamines; Dysautonomia, Familial; E | 1971 |
[Impotence caused by nerve injuries].
Topics: Adult; Erectile Dysfunction; Humans; Male; Neostigmine; Nervous System Diseases; Spinal Cord Injurie | 1970 |