Page last updated: 2024-10-31

neostigmine and Sleep Apnea, Obstructive

neostigmine has been researched along with Sleep Apnea, Obstructive in 2 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

ExcerptRelevanceReference
"Patients with obstructive sleep apnea (OSA) may be at higher risk of complications related to the use of NMBD."2.58Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review. ( Chung, F; Hafeez, KR; Nagappa, M; Singh, M; Tuteja, A; Wong, DT; Wong, J, 2018)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Korkmaz, MO1
Sayhan, H1
Guven, M1
Hafeez, KR1
Tuteja, A1
Singh, M1
Wong, DT1
Nagappa, M1
Chung, F1
Wong, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium: A Pharmacodynamic Modelling Study[NCT03737942]60 participants (Anticipated)Observational2018-11-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for neostigmine and Sleep Apnea, Obstructive

ArticleYear
Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review.
    BMC anesthesiology, 2018, 07-19, Volume: 18, Issue:1

    Topics: Humans; Neostigmine; Neuromuscular Blocking Agents; Parasympathomimetics; Postoperative Complication

2018

Trials

1 trial available for neostigmine and Sleep Apnea, Obstructive

ArticleYear
Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
    Saudi medical journal, 2019, Volume: 40, Issue:9

    Topics: Adenoidectomy; Adolescent; Anesthesia, General; Atropine; Child; Child, Preschool; Cough; Double-Bli

2019