Page last updated: 2024-10-31

neostigmine and Schizophrenia

neostigmine has been researched along with Schizophrenia in 9 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Clozapine is an antipsychotic drug which is used in the treatment of therapy-resistant schizophrenia."3.75[Ogilvie Syndrome induced by clozapine]. ( Bac, DJ; de Bruin, GJ; van der Klooster, JM; van Puijenbroek, EP, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Bruin, GJ1
Bac, DJ1
van Puijenbroek, EP1
van der Klooster, JM1
HOFFER, A1
ABELY, P1
RICHARDEAU, N1
DEDIEU-ANGLADE, G1
BENOIT, JC1
Davis, JM3
Schnackenberg, RC1
Holmes, G1
Modestin, J1
Schwartz, RB1
Hunger, J1
Janowsky, DS2
el-Yousef, K1
Sekerke, HJ2
Gittleson, NL1
Richardson, TD1
el-Yousef, MK1

Trials

2 trials available for neostigmine and Schizophrenia

ArticleYear
[Investigation about an influence of physostigmine on schizophrenic symptoms (author's transl)].
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1973, Volume: 6, Issue:6

    Topics: Adult; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Neostigmine; Physost

1973
Parasympathetic suppression of manic symptoms by physostigmine.
    Archives of general psychiatry, 1973, Volume: 28, Issue:4

    Topics: Acetylcholine; Adult; Affect; Bipolar Disorder; Brain Chemistry; Dopamine; Dose-Response Relationshi

1973

Other Studies

7 other studies available for neostigmine and Schizophrenia

ArticleYear
[Ogilvie Syndrome induced by clozapine].
    Nederlands tijdschrift voor geneeskunde, 2009, Volume: 153

    Topics: Adult; Antipsychotic Agents; Clozapine; Colonic Pseudo-Obstruction; Gastrointestinal Transit; Humans

2009
Induction of sleep by autonomic drugs.
    The Journal of nervous and mental disease, 1954, Volume: 119, Issue:5

    Topics: Acetylcholine; Atropine; Autonomic Agents; Epilepsy; Humans; Neostigmine; Schizophrenia; Schizophren

1954
[Cutaneo-abdominal reflexes in conflict syndromes; caffeine, acecoline, prostigmine & adrenalin control tests; probable anticataionic role of adrenalin in the human].
    Annales medico-psychologiques, 1959, Volume: 117, Issue:3

    Topics: Caffeine; Epinephrine; Humans; Neostigmine; Probability; Schizophrenia; Syndrome

1959
Critique of single amine theories: evidence of a cholinergic influence in the major mental illnesses.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Diso

1975
Coexisting childhood schizophrenia and myasthenia gravis treated successfully with neostigmine bromide.
    The American journal of psychiatry, 1977, Volume: 134, Issue:9

    Topics: Acetylcholine; Child; Follow-Up Studies; Humans; Hypothyroidism; Male; Myasthenia Gravis; Neostigmin

1977
Myasthenia gravis and schizophrenia--a rare combination.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 122, Issue:568

    Topics: Aged; Chlorpromazine; Humans; Male; Myasthenia Gravis; Neostigmine; Schizophrenia

1973
Antagonistic effects of physostigmine and methylphenidate in man.
    The American journal of psychiatry, 1973, Volume: 130, Issue:12

    Topics: Affective Symptoms; Behavior; Bipolar Disorder; Humans; Inhibition, Psychological; Methylphenidate;

1973