Page last updated: 2024-10-31

neostigmine and Respiratory Insufficiency

neostigmine has been researched along with Respiratory Insufficiency in 42 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality."6.94Neostigmine Versus Sugammadex for Reversal of Neuromuscular Blockade and Effects on Reintubation for Respiratory Failure or Newly Initiated Noninvasive Ventilation: An Interrupted Time Series Design. ( Bartels, K; Bullard, KJ; Fernandez-Bustamante, A; Jameson, LC; Krause, M; Mayes, LM; McWilliams, SK; Mikulich-Gilbertson, SK, 2020)
"Neostigmine reversal did not affect oxygenation but was associated with increased atelectasis."3.80Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study. ( Doran, ME; Eikermann, M; Hoang, AH; Igumenshcheva, A; MacDonald, T; Malviya, SA; Meyer, MJ; Sasaki, N; Stanislaus, AB, 2014)
" Simultaneous measurement of gastrocnemius muscle contraction and efferent phrenic nerve activity was used to determine the primary cause of respiratory failure produced by neostigmine and diisopropyl fluorophosphate (DFP) in anesthetized cats."3.68Mechanisms of respiratory failure produced by neostigmine and diisopropyl fluorophosphate. ( Dretchen, KL; Fleming, NW; Henderson, TR, 1991)
" The most likely cause was the return of muscle paralysis after the apparent antagonism of tubocurarine by neostigmine (recurarization)."3.65Renal failure and postoperative respiratory failure: recurarization? ( Cullen, DJ; Miller, RD, 1976)
"Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality."2.94Neostigmine Versus Sugammadex for Reversal of Neuromuscular Blockade and Effects on Reintubation for Respiratory Failure or Newly Initiated Noninvasive Ventilation: An Interrupted Time Series Design. ( Bartels, K; Bullard, KJ; Fernandez-Bustamante, A; Jameson, LC; Krause, M; Mayes, LM; McWilliams, SK; Mikulich-Gilbertson, SK, 2020)
"A 59-year-old man with chronic renal failure underwent the ascending colectomy."1.37[Neuromuscular blockade after a chain of two laparotomies in a few hours]. ( Saito, A; Takahashi, H; Yamazaki, Y, 2011)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199022 (52.38)18.7374
1990's1 (2.38)18.2507
2000's2 (4.76)29.6817
2010's6 (14.29)24.3611
2020's11 (26.19)2.80

Authors

AuthorsStudies
Beltran, RJ1
Mpody, C1
Nafiu, OO1
Tobias, JD1
Colquhoun, DA1
Vaughn, MT1
Bash, LD1
Janda, A1
Shah, N1
Ghaferi, A1
Sjoding, M1
Mentz, G1
Kheterpal, S1
Liu, H1
Luo, R1
Cao, S1
Zheng, B1
Ye, L1
Zhang, W1
Scheffenbichler, FT1
Rudolph, MI1
Friedrich, S1
Althoff, FC1
Xu, X2
Spicer, AC1
Patrocínio, M1
Ng, PY1
Deng, H1
Anderson, TA1
Eikermann, M6
Krause, M3
McWilliams, SK1
Bullard, KJ1
Mayes, LM1
Jameson, LC1
Mikulich-Gilbertson, SK1
Fernandez-Bustamante, A3
Bartels, K3
Thilen, SR1
Weigel, WA1
Togioka, BM1
Banner-Goodspeed, V1
Karim, HMR1
Bhakta, P1
O'Brien, B1
Esquinas, AM1
Ledowski, T1
Szabó-Maák, Z1
Loh, PS1
Turlach, BA1
Yang, HS1
de Boer, HD1
Asztalos, L1
Shariffuddin, II1
Chan, L1
Fülesdi, B1
Meyer, MJ3
Bateman, BT2
Kurth, T2
Sasaki, N2
Malviya, SA1
Stanislaus, AB1
MacDonald, T1
Doran, ME1
Igumenshcheva, A1
Hoang, AH1
Kopman, AF1
Naguib, M1
Beccaria, P1
Cabrini, L1
Garancini, MP1
Colombo, S1
Yamazaki, Y1
Saito, A1
Takahashi, H1
Grosse-Sundrup, M1
Henneman, JP1
Sandberg, WS1
Uribe, JV1
Nguyen, NT1
Ehrenfeld, JM1
Martinez, EA1
Keesey, JC1
REAM, CR1
RANKIN, AM1
FARDEAU, M1
HEAD, JM1
LAPRESLE, J1
BOUDIN, G1
GOULON, M1
HAMBURGER, J1
LHERMITTE, F1
PEQUIGNOT, H1
SMIRNOV, IuK1
ASHMARINA, EE1
ANDREEVA, LS1
Percy, AK1
Saef, EC1
Sher, MH1
Mathews, PA1
Miller, RD1
Cullen, DJ1
Fleming, NW1
Henderson, TR1
Dretchen, KL1
Hall, LW1
Kellagher, RE1
Watkins, SB1
Sellman, MS1
Mayer, RF1
Tseng, J1
Manani, G1
Galzigna, L1
Mammano, S1
Gasparetto, A1
Leroy, J1
Robert, M1
Delaunay, P1
Dordain, M1
McQuillen, MP1
Cantor, HA1
O'Rourke, JR1
Black, JT1
Brait, KA1
DeJesus, PV1
Harner, RN1
Rowland, LP1
Erbslöh, F1
Draxler, V1
Mitsudome, A1
Takeshita, K1
Matsumoto, T1
Decker, DA1
Fincham, RW1
Zaffiri, O1
Francescato, F1
Del Prete, D1
Alessio-Vernì, A1
Older, P1
Harris, JM1
Mitchard, M1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficiency And Quality In Post-Surgical Pain Therapy After Discharge[NCT05221866]711 participants (Actual)Interventional2022-03-14Completed
Electromyographic Activity of the Diaphragm and of the Rectus Abdominis and Intercostal Muscles During Neostigmine, Sugammadex, or Neostigmine-sugammadex Enhanced Recovery After Neuromuscular Blockade With Rocuronium. A Randomised Controlled Study in Heal[NCT02403063]Phase 418 participants (Actual)Interventional2015-09-30Completed
A Randomized, Blinded-assessor, Single Center Study to Determine if Administration of Sugammadex, When Used to Reverse Deep Neuromuscular Blockade (NMB) After Open Abdominal Surgery, Impacts Hospital Efficiency[NCT02860507]Phase 450 participants (Actual)Interventional2016-08-31Completed
Effects of Postoperative Residual Paralysis on Costs of Hospital Care, Length of Hospitalization and Intensive Care Unit Admission Rate[NCT01718860]3,000 participants (Anticipated)Observational2011-04-30Active, not recruiting
The Effect of Intraoperative Neuromuscular Blockade on Postoperative Atelectasis in Patients Undergoing Thoracic Surgery With One Lung Ventilation: Moderate vs. Deep Block[NCT03503565]118 participants (Actual)Observational2018-10-11Completed
Visualization of Regional Lung Ventilation During Neostigmine or Sugammadex Enhanced Recovery From Moderate Residual Neuromuscular Blockade in the Anaesthetized Rat Using Functional Respiratory Imaging[NCT02284412]Phase 413 participants (Actual)Interventional2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Patients Who Experience Postoperative Nausea and Vomiting, Post-operative Pain, and Post-operative Complications

(NCT02860507)
Timeframe: through discharge from hospital, average of 72 hours

InterventionParticipants (Count of Participants)
Neostigmine + Glycopyrrolate8
Sugammadex10

Operating Room (OR) Turnover Time When Using Sugammadex Instead of Combination of Neostigmine and Glycopyrrolate.

(NCT02860507)
Timeframe: through start of next surgery, average of 2 hours

InterventionMinutes (Mean)
Neostigmine + Glycopyrrolate49.7
Sugammadex49.45

Atelectasis Area on Chest CT

Atelectasis on Chest CT The lung area was delineated manually. To calculate atelectasis, a region of interest was laid out that encircled the dense part of the lung, excluding large vessels. For further analysis, the lung was divided into four categories: areas with densities ranging from -1000 to -900 Hounsfield units (HU) were classified as over-aerated, from -900 to -500 HU as normally aerated, from -500 to -100 HU as poorly aerated, and from -100 to +100 HU as non-aerated (atelectasis). The proportion of non-aerated lung tissue (-100 to +100 HU) was calculated by dividing the area of the region of interest with the whole lungs. (NCT03503565)
Timeframe: 1 day after the end of surgery

Interventionpercentage of atelectasis volume (Median)
Moderate Block Group1.32
Deep Block Group1.41

Reviews

2 reviews available for neostigmine and Respiratory Insufficiency

ArticleYear
Superiority of sugammadex in preventing postoperative pulmonary complications.
    Chinese medical journal, 2023, Jul-05, Volume: 136, Issue:13

    Topics: Humans; Neostigmine; Neuromuscular Blockade; Pneumonia; Postoperative Complications; Respiratory Ins

2023
[Current therapy of myasthenia gravis. I. Specific symptomatic therapy].
    Der Nervenarzt, 1972, Volume: 43, Issue:7

    Topics: Ambenonium Chloride; Anti-Bacterial Agents; Edrophonium; Enteral Nutrition; Ephedrine; Humans; Myast

1972

Trials

2 trials available for neostigmine and Respiratory Insufficiency

ArticleYear
Neostigmine Versus Sugammadex for Reversal of Neuromuscular Blockade and Effects on Reintubation for Respiratory Failure or Newly Initiated Noninvasive Ventilation: An Interrupted Time Series Design.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:1

    Topics: Adult; Aged; Cholinesterase Inhibitors; Delayed Emergence from Anesthesia; Female; Humans; Interrupt

2020
Reversal of residual neuromuscular block with neostigmine or sugammadex and postoperative pulmonary complications: a prospective, randomised, double-blind trial in high-risk older patients.
    British journal of anaesthesia, 2021, Volume: 127, Issue:2

    Topics: Aged; Aged, 80 and over; Australia; Cholinesterase Inhibitors; Double-Blind Method; Female; Geriatri

2021

Other Studies

38 other studies available for neostigmine and Respiratory Insufficiency

ArticleYear
Association of Sugammadex or Neostigmine With Major Postoperative Pulmonary Complications in Children.
    Anesthesia and analgesia, 2022, 11-01, Volume: 135, Issue:5

    Topics: Adult; Child; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Postoperative

2022
Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Cholinesterase Inhibitors; Cohort Studies; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscula

2023
Effects of high neuromuscular blocking agent dose on post-operative respiratory complications in infants and children.
    Acta anaesthesiologica Scandinavica, 2020, Volume: 64, Issue:2

    Topics: Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neostigmine; Neuromuscular B

2020
Sugammadex: A Costly Simple Solution That Is Not Really Solving the Problem.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:2

    Topics: Humans; Interrupted Time Series Analysis; Neostigmine; Neuromuscular Blockade; Noninvasive Ventilati

2020
In Response.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:2

    Topics: Humans; Interrupted Time Series Analysis; Neostigmine; Neuromuscular Blockade; Noninvasive Ventilati

2020
Does Sugammadex Reduce Postoperative Airway Failure?
    Anesthesia and analgesia, 2020, Volume: 131, Issue:1

    Topics: Humans; Interrupted Time Series Analysis; Neostigmine; Neuromuscular Blockade; Noninvasive Ventilati

2020
Despite Its Association With Less Postoperative Respiratory Failure, the Superiority of Sugammadex Over Neostigmine Remains Questionable.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:2

    Topics: Cholinesterase Inhibitors; Humans; Interrupted Time Series Analysis; Neostigmine; Neuromuscular Bloc

2020
In Response.
    Anesthesia and analgesia, 2020, Volume: 131, Issue:2

    Topics: Humans; Interrupted Time Series Analysis; Neostigmine; Neuromuscular Blockade; Noninvasive Ventilati

2020
Neostigmine reversal doesn't improve postoperative respiratory safety.
    BMJ (Clinical research ed.), 2013, Mar-19, Volume: 346

    Topics: Adult; Aged; Case-Control Studies; Female; Humans; Intraoperative Care; Male; Middle Aged; Neostigmi

2013
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Neostigmine: You Can't Have It Both Ways.
    Anesthesiology, 2015, Volume: 123, Issue:1

    Topics: Female; Humans; Male; Neostigmine; Neuromuscular Nondepolarizing Agents; Parasympathomimetics; Posto

2015
In Reply.
    Anesthesiology, 2015, Volume: 123, Issue:1

    Topics: Female; Humans; Male; Neostigmine; Neuromuscular Nondepolarizing Agents; Parasympathomimetics; Posto

2015
Recurarisation in a surgical ward.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:6

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, General; Anes

2008
[Neuromuscular blockade after a chain of two laparotomies in a few hours].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60, Issue:2

    Topics: Colectomy; Foreign Bodies; Humans; Kidney Failure, Chronic; Laparotomy; Male; Middle Aged; Neostigmi

2011
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
"Crisis" in myasthenia gravis: an historical perspective.
    Muscle & nerve, 2002, Volume: 26, Issue:1

    Topics: Cholinesterase Inhibitors; Emergency Medical Services; History, 20th Century; History, 21st Century;

2002
RESPIRATORY AND CARDIAC ARREST AFTER INTRAVENOUS ADMINISTRATION OF KANAMYCIN WITH REVERSAL OF TOXIC EFFECTS BY NEOSTIGMINE.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Abscess; Administration, Intravenous; Adolescent; Appendix; Drug Hypersensitivity; Escherichia coli

1963
A MYASTHENIC CRISIS: DOMICILIARY EMERGENCY TREATED BY PROLONGED MOUTH-TO- MOUTH ARTIFICIAL RESPIRATION.
    British medical journal, 1963, Dec-28, Volume: 2, Issue:5373

    Topics: Cell Respiration; Emergencies; Humans; Mouth; Myasthenia Gravis; Neostigmine; Respiration; Respirati

1963
[MYASTHENIA].
    La Revue du praticien, 1964, Feb-11, Volume: 14

    Topics: Ammonium Compounds; Blood; Cardiovascular Agents; Child; Diagnosis; Endocrinology; Ephedrine; Guanid

1964
RESPIRATORY FAILURE AFTER THYMECTOMY FOR MYASTHENIA GRAVIS.
    Annals of surgery, 1964, Volume: 160

    Topics: Humans; Myasthenia Gravis; Neoplasms; Neostigmine; Pharmacology; Postoperative Care; Respiratory Ins

1964
[HOW TO TREAT MYASTHENIA].
    La Presse medicale, 1964, Oct-10, Volume: 72

    Topics: Ambenonium Chloride; Ephedrine; Humans; Muscle Weakness; Myasthenia Gravis; Neostigmine; Physostigmi

1964
[PRIMARY POLYRADICULONEURITIS IN CHILDREN].
    Pediatriia, 1964, Volume: 43

    Topics: Child; Drug Therapy; Folic Acid; Humans; Neostigmine; Polyradiculoneuropathy; Polyradiculopathy; Pre

1964
An unusual complication of retrograde pyelography: neuromuscular blockade.
    Pediatrics, 1967, Volume: 39, Issue:4

    Topics: Humans; Infant, Newborn; Male; Neomycin; Neostigmine; Neuromuscular Junction; Respiratory Insufficie

1967
Recurarization with quinine administration after reversal from anaesthesia.
    Anaesthesia and intensive care, 1983, Volume: 11, Issue:3

    Topics: Atropine; Drug Interactions; Humans; Male; Middle Aged; Neostigmine; Nerve Block; Neuromuscular Junc

1983
Renal failure and postoperative respiratory failure: recurarization?
    British journal of anaesthesia, 1976, Volume: 48, Issue:3

    Topics: Adult; Anesthesia, General; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Neostigmine;

1976
Mechanisms of respiratory failure produced by neostigmine and diisopropyl fluorophosphate.
    European journal of pharmacology, 1991, Mar-19, Volume: 195, Issue:1

    Topics: Animals; Atropine; Cats; Cholinesterase Inhibitors; Female; In Vitro Techniques; Isoflurophate; Male

1991
Respiratory problems after atropine and neostigmine in dogs.
    British journal of anaesthesia, 1985, Volume: 57, Issue:10

    Topics: Anesthesia; Animals; Atracurium; Atropine; Dog Diseases; Dogs; Isoquinolines; Neostigmine; Neuromusc

1985
Treatment of myasthenic crisis in late life.
    Southern medical journal, 1985, Volume: 78, Issue:10

    Topics: Adult; Aged; Cholinesterase Inhibitors; Combined Modality Therapy; Edrophonium; Female; Humans; Male

1985
[Clinical and experimental studies on the mechanism of neuromucular blockade by chloroquine diorotate].
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:6

    Topics: Action Potentials; Adolescent; Adult; Aged; Animals; Anura; Calcium Chloride; Chloroquine; Dogs; Ele

1971
Experimental and clinical study of the effects of pancuronium bromide, a neuromuscular blocking agent.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:9

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Androstanes; Animals; Bromides; Dogs; Drug Synergism

1972
[Apropos of myasthenia gravis and its treatment].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, May-20, Volume: 45, Issue:24

    Topics: Ambenonium Chloride; Immunosuppressive Agents; Myasthenia Gravis; Neostigmine; Pyridostigmine Bromid

1969
Myasthenic syndrome associated with antibiotics.
    Transactions of the American Neurological Association, 1967, Volume: 92

    Topics: Calcium; Colistin; Electromyography; Humans; Hypocalcemia; Kanamycin; Male; Middle Aged; Myasthenia

1967
Myasthenia gravis lacking response to cholinergic drugs.
    Neurology, 1973, Volume: 23, Issue:8

    Topics: Adrenocorticotropic Hormone; Autopsy; Diagnosis, Differential; Edrophonium; Electric Stimulation; Fe

1973
[Acute respiratory dishess syndrome due to high dosage of penicilline in a case of myasthenia gravis (author's transl)].
    Der Anaesthesist, 1973, Volume: 22, Issue:11

    Topics: Adult; Apnea; Atropine; Drug Hypersensitivity; Female; Humans; Myasthenia Gravis; Neostigmine; Penic

1973
[Crisis in myasthenia gravis in infancy and childhood].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1971, Volume: 15, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Cholinesterase Inhibitors; Cognition Disorders; Deglutition Dis

1971
Respiratory arrest in myasthenia gravis with colistimethate therapy.
    Archives of neurology, 1971, Volume: 25, Issue:2

    Topics: Aged; Ampicillin; Carbenicillin; Colistin; Edrophonium; Humans; Male; Medication Errors; Myasthenia

1971
[Prolonged curarization of the non depolarizing type, resistant to neostigmine and resolved with nivaline].
    Minerva anestesiologica, 1967, Volume: 33, Issue:9

    Topics: Adjuvants, Anesthesia; Female; Galantamine; Humans; Middle Aged; Neostigmine; Respiratory Insufficie

1967
Respiratory depression following the use of tacrine and suxamethonium. A case report.
    British journal of anaesthesia, 1966, Volume: 38, Issue:6

    Topics: Adult; Cholinesterase Inhibitors; Female; Humans; Neostigmine; Respiration; Respiratory Insufficienc

1966