Page last updated: 2024-10-31

neostigmine and Respiration Disorders

neostigmine has been researched along with Respiration Disorders in 10 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.

Research Excerpts

ExcerptRelevanceReference
" The authors hypothesized that the choice of neuromuscular blockade reversal (neostigmine vs."7.96Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis. ( Bardia, A; Bartels, K; Bash, LD; Colquhoun, DA; Dubovoy, TZ; Kheterpal, S; Mathis, MR; McCormick, PJ; Saager, L; Schonberger, RB; Shah, NJ; Shanks, AM; Soto, RG; Vaughn, MT, 2020)
"Prospective observational series of consecutive patients scheduled for laparoscopic bariatric surgery in whom neuromuscular blockade was reverted with sugammadex were compared with a historical matched cohort of patients reverted with neostigmines."7.80Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine. ( Cabrera, A; Camprubí, I; Ferreres, E; Llauradó, S; Sabaté, A, 2014)
" The authors hypothesized that the choice of neuromuscular blockade reversal (neostigmine vs."3.96Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis. ( Bardia, A; Bartels, K; Bash, LD; Colquhoun, DA; Dubovoy, TZ; Kheterpal, S; Mathis, MR; McCormick, PJ; Saager, L; Schonberger, RB; Shah, NJ; Shanks, AM; Soto, RG; Vaughn, MT, 2020)
"Prospective observational series of consecutive patients scheduled for laparoscopic bariatric surgery in whom neuromuscular blockade was reverted with sugammadex were compared with a historical matched cohort of patients reverted with neostigmines."3.80Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine. ( Cabrera, A; Camprubí, I; Ferreres, E; Llauradó, S; Sabaté, A, 2014)
"Neostigmine was associated with a dose-dependent increase in the risk of postoperative respiratory complications (OR, 1."1.42Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications. ( Diaz-Gil, D; Eikermann, M; Farhan, HN; Kurth, T; Ladha, KS; McLean, DJ, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Suleiman, A1
Munoz-Acuna, R1
Azimaraghi, O1
Houle, TT1
Chen, G1
Rupp, S1
Witt, AS1
Azizi, BA1
Ahrens, E1
Shay, D1
Wongtangman, K1
Wachtendorf, LJ1
Tartler, TM1
Eikermann, M2
Schaefer, MS1
Ji, Y1
Yuan, H1
Chen, Y1
Zhang, X1
Wu, F1
Tang, W1
Lu, Z1
Huang, C1
Kheterpal, S1
Vaughn, MT1
Dubovoy, TZ1
Shah, NJ1
Bash, LD1
Colquhoun, DA1
Shanks, AM1
Mathis, MR1
Soto, RG1
Bardia, A1
Bartels, K1
McCormick, PJ1
Schonberger, RB1
Saager, L1
Piskin, O1
Altinsoy, B1
Cimencan, M1
Aydin, BG1
Okyay, D1
Kucukosman, G1
Tascilar, O1
Sarikaya, S1
Ayoglu, H1
Llauradó, S1
Sabaté, A1
Ferreres, E1
Camprubí, I1
Cabrera, A1
McLean, DJ1
Diaz-Gil, D1
Farhan, HN1
Ladha, KS1
Kurth, T1
Martinez-Ubieto, J1
Ortega-Lucea, S1
Pascual-Bellosta, A1
Arazo-Iglesias, I1
Gil-Bona, J1
Jimenez-Bernardó, T1
Muñoz-Rodriguez, L1
Cammu, GV1
Smet, V1
De Jongh, K1
Vandeput, D1
Gawley, TH1
Dundee, JW1
Lobzin, VS1
Saĭkova, LA1
Poliakova, LA1
Vasil'ev, VN1
Zhulev, NM1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Validation of the REPS Prediction Tool to Improve Quality of Perioperative Care[NCT03585400]101,510 participants (Actual)Observational2018-06-29Completed
Importance of Understanding Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal Agents[NCT03585348]265,537 participants (Actual)Observational2018-06-29Completed
Accessor Blinded Randomized Controlled Study Evaluating the Efficacy and Safety of Sugammadex in High-Risk Ambulatory Surgeries[NCT03944473]Phase 40 participants (Actual)Interventional2019-06-20Withdrawn (stopped due to Stopped before IRB approval)
Neuromuscular Monitoring, Reversal of Block and Postoperative Residual Curarization: the Situation in 2018[NCT03665805]587 participants (Actual)Observational2018-07-30Completed
Visualization of Regional Lung Ventilation During Neostigmine or Sugammadex Enhanced Recovery From Moderate Residual Neuromuscular Blockade in the Anaesthetized Rat Using Functional Respiratory Imaging[NCT02284412]Phase 413 participants (Actual)Interventional2014-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for neostigmine and Respiration Disorders

ArticleYear
Sugammadex Is Associated With Reduced Pulmonary Complications in Patients With Respiratory Dysfunction.
    The Journal of surgical research, 2023, Volume: 290

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Pleural Effusion; Postoperat

2023

Trials

1 trial available for neostigmine and Respiration Disorders

ArticleYear
Attempts to reduce respiratory complications following upper abdominal operations.
    British journal of anaesthesia, 1981, Volume: 53, Issue:10

    Topics: Abdomen; Adolescent; Adult; Anesthesia; Carbon Dioxide; Hot Temperature; Humans; Humidity; Middle Ag

1981

Other Studies

8 other studies available for neostigmine and Respiration Disorders

ArticleYear
The effects of sugammadex vs. neostigmine on postoperative respiratory complications and advanced healthcare utilisation: a multicentre retrospective cohort study.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Adult; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Patient Acceptance of

2023
Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis.
    Anesthesiology, 2020, Volume: 132, Issue:6

    Topics: Cholinesterase Inhibitors; Cohort Studies; Female; Humans; Male; Middle Aged; Neostigmine; Neuromusc

2020
The effect of bariatric anaesthesia on postoperative pulmonary functions.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Bariatric Surgery; Bl

2017
Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine.
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:10

    Topics: Adult; Aged; Bariatric Surgery; Cholinesterase Inhibitors; Female; gamma-Cyclodextrins; Humans; Lapa

2014
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Prospective study of residual neuromuscular block and postoperative respiratory complications in patients reversed with neostigmine versus sugammadex.
    Minerva anestesiologica, 2016, Volume: 82, Issue:7

    Topics: Anesthesia Recovery Period; Atracurium; Cholinesterase Inhibitors; Delayed Emergence from Anesthesia

2016
A prospective, observational study comparing postoperative residual curarisation and early adverse respiratory events in patients reversed with neostigmine or sugammadex or after apparent spontaneous recovery.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:6

    Topics: Adult; Aged; Anesthesia Recovery Period; Body Mass Index; Female; gamma-Cyclodextrins; Humans; Male;

2012
A prospective, observational study comparing postoperative residual curarisation and early adverse respiratory events in patients reversed with neostigmine or sugammadex or after apparent spontaneous recovery.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:6

    Topics: Adult; Aged; Anesthesia Recovery Period; Body Mass Index; Female; gamma-Cyclodextrins; Humans; Male;

2012
A prospective, observational study comparing postoperative residual curarisation and early adverse respiratory events in patients reversed with neostigmine or sugammadex or after apparent spontaneous recovery.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:6

    Topics: Adult; Aged; Anesthesia Recovery Period; Body Mass Index; Female; gamma-Cyclodextrins; Humans; Male;

2012
A prospective, observational study comparing postoperative residual curarisation and early adverse respiratory events in patients reversed with neostigmine or sugammadex or after apparent spontaneous recovery.
    Anaesthesia and intensive care, 2012, Volume: 40, Issue:6

    Topics: Adult; Aged; Anesthesia Recovery Period; Body Mass Index; Female; gamma-Cyclodextrins; Humans; Male;

2012
[Criteria for severity and prognosis of the course of myasthenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1985, Volume: 85, Issue:11

    Topics: Adolescent; Adult; Aged; Cholinesterase Inhibitors; Electromyography; Female; Humans; Male; Middle A

1985