neostigmine has been researched along with Parkinson Disease in 5 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neostigmine was recently shown to be effective and safe for the treatment of Ogilvie's syndrome." | 1.31 | [Neostigmine treatment of acute pseudo-obstruction of colon (Ogilvie syndrome)]. ( Klaver, NS; Koornstra, JJ; Limburg, AJ; ter Maaten, JC; van der Jagt, EJ; van der Werf, TS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaleska, B | 1 |
| Koornstra, JJ | 1 |
| Klaver, NS | 1 |
| ter Maaten, JC | 1 |
| Limburg, AJ | 1 |
| van der Jagt, EJ | 1 |
| van der Werf, TS | 1 |
| Poloni, M | 1 |
| Tartara, A | 1 |
| Nappi, G | 1 |
| Savoldi, F | 1 |
| Duvoisin, RC | 1 |
| Katz, R | 1 |
| Stern, FH | 1 |
1 review available for neostigmine and Parkinson Disease
| Article | Year |
|---|---|
[Progress in the treatment of degenerative diseases of the nervous system. Selected problems].
Topics: Amyotrophic Lateral Sclerosis; Antiparkinson Agents; Humans; Huntington Disease; Lithium; Neostigmin | 1980 |
4 other studies available for neostigmine and Parkinson Disease
| Article | Year |
|---|---|
[Neostigmine treatment of acute pseudo-obstruction of colon (Ogilvie syndrome)].
Topics: Aged; Colonic Pseudo-Obstruction; Humans; Infusions, Intravenous; Intestinal Perforation; Male; Neos | 2001 |
Proceedings: EEG modification during Jendrassik's manoeuvre before and after prostigmine in Parkinsonian subjects.
Topics: Electroencephalography; Humans; Neostigmine; Parkinson Disease | 1975 |
Reversal of central anticholinergic syndrome in man by physostigmine.
Topics: Aged; Ataxia; Central Nervous System Diseases; Child; Cognition Disorders; Delirium; Female; Halluci | 1968 |
Myasthenia gravis, an often overlooked disease in the geriatric group.
Topics: Adrenal Insufficiency; Aged; Amyotrophic Lateral Sclerosis; Chronic Disease; Curare; Diagnosis, Diff | 1966 |