Page last updated: 2024-10-31

neostigmine and Pain, Postoperative

neostigmine has been researched along with Pain, Postoperative in 84 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium after pars plana vitrectomy (PPV) under general anesthesia."9.30Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: A prospective, randomized, double-blinded, controlled study. ( Bai, SJ; Hong, JH; Kim, NY; Kim, SS; Koh, JC; Lee, KY; Nam, HJ, 2019)
"Calcium chloride coadministered with neostigmine enhanced neuromuscular recovery in the early period of nondepolarising neuromuscular blockade reversal."9.24Effects of calcium chloride coadministered with neostigmine on neuromuscular blockade recovery: A double-blind randomised study. ( Hong, DM; Ju, JW; Kim, HC; Park, HP; Yoon, S, 2017)
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."9.10Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"p) on preventing epidural-morphine-induced urinary retention and effects of neostigmine on releasing it."9.09[Prevention and release of epidural-morphine-induced urinary retention with phenoxybenzamine and neostigmine]. ( Tang, J; Xu, Q; Ye, T, 2000)
"Neostigmine is a parasympathomimetic agent that has been recently investigated for use as an adjunct analgesic agent in the perioperative and peripartum period."6.43Use of neostigmine in the management of acute postoperative pain and labour pain: a review. ( Gan, TJ; Habib, AS, 2006)
"To evaluate the influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium after pars plana vitrectomy (PPV) under general anesthesia."5.30Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: A prospective, randomized, double-blinded, controlled study. ( Bai, SJ; Hong, JH; Kim, NY; Kim, SS; Koh, JC; Lee, KY; Nam, HJ, 2019)
"Calcium chloride coadministered with neostigmine enhanced neuromuscular recovery in the early period of nondepolarising neuromuscular blockade reversal."5.24Effects of calcium chloride coadministered with neostigmine on neuromuscular blockade recovery: A double-blind randomised study. ( Hong, DM; Ju, JW; Kim, HC; Park, HP; Yoon, S, 2017)
"Rocuronium for cesarean delivery under general anesthesia is an alternative to succinylcholine for rapid-sequence induction of anesthesia because of the availability of sugammadex for reversal of neuromuscular blockade."5.22Low-Dose or High-Dose Rocuronium Reversed with Neostigmine or Sugammadex for Cesarean Delivery Anesthesia: A Randomized Controlled Noninferiority Trial of Time to Tracheal Intubation and Extubation. ( Adamus, M; Bartikova, I; Francakova, J; Harazim, H; Hejduk, K; Hlozkova, J; Hodicka, Z; Janku, P; Kirchnerova, M; Klucka, J; Kosinova, M; Krikava, I; Mrozek, Z; Obare Pyszkova, L; Pavlik, T; Prochazka, M; Robotkova, H; Seidlova, D; Sevcik, P; Stoudek, R; Stourac, P, 2016)
"Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery."5.10Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002)
"p) on preventing epidural-morphine-induced urinary retention and effects of neostigmine on releasing it."5.09[Prevention and release of epidural-morphine-induced urinary retention with phenoxybenzamine and neostigmine]. ( Tang, J; Xu, Q; Ye, T, 2000)
"We evaluated the effect of a single dose of dexamethasone on the incidence and severity of postoperative nausea and vomiting (PONV) after intrathecal injection of tetracaine plus neostigmine."5.09The effect of dexamethasone on postoperative pain and emesis after intrathecal neostigmine. ( Lin, CR; Liu, K; Lu, CY; Peng, CH; Tan, PH; Yang, LC, 2001)
" morphine 100 microg, but with a high incidence of nausea and vomiting."5.08The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia. ( Chin, YJ; Chung, CJ; Kim, JS; Park, HS, 1998)
" Opioids are used in routinely, but alpha2-agonists, such as clonidine or cholinesterase inhibitors (neostigmine), have also been used for labour analgesia or to relieve pain following caesarean section."4.83The use of neuraxial adjuvant drugs (neostigmine, clonidine) in obstetrics. ( Roelants, F, 2006)
"Seventeen patients with postcholecystectomy pain and nine controls were studied by nonoperative biliary manometry with stimulation of sphincter of Oddi spasm by morphine."3.67Manometric diagnosis of sphincter of Oddi spasm as a cause of postcholecystectomy pain and the treatment by endoscopic sphincterotomy. ( Ikeda, S; Matsumoto, S; Nakayama, F; Tanaka, M; Yoshimoto, H, 1985)
"Neostigmine was co-administered with caudal bupivacaine to shorten the onset and extend the duration of analgesia."3.30Ultrasound-guided Techniques for Perioperative Analgesia in Pediatric Lower Abdominal Surgeries: Quadratus Lumborum Block with Bupivacaine versus Caudal Bupivacaine and Neostigmine. ( Ashoor, TM; Esmat, IM; Hasseb, AM; Reyad, MK; Zain, EM, 2023)
"The primary outcome is the postoperative pain scores."3.30Effects of Thoracic Paravertebral Block on Postoperative Analgesia in Infants and Small Children undergoing Ultra-Fast Track Cardiac Anesthesia: A Randomized Controlled Trial. ( Feng, J; Peng, L; Song, X; Wang, H; Xu, H, 2023)
"However, the effect of this agent in postoperative pain is still unknown."2.79Sugammadex reduces postoperative pain after laparoscopic bariatric surgery: a randomized trial. ( Borges, S; Castro, DS; Figueiredo, P; Gomes, L; Leão, P; Pacheco, M, 2014)
"When administered epidurally, morphine alone or in combination with neostigmine provided effective postoperative analgesia in most dogs after orthopedic surgery, whereas neostigmine alone did not."2.79Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in dogs undergoing orthopedic surgery of the pelvic limbs. ( Fantoni, DT; Marucio, RL; Monteiro, ER; Moroz, LR, 2014)
"To evaluate analgesic effects of epidurally administered neostigmine alone or in combination with morphine in dogs after ovariohysterectomy."2.73Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs. ( Hatschbach, E; Luna, SP; Marucio, RL; Minto, BW; Neto, FJ, 2008)
" Opiate dosage consumed was also recorded as a primary outcome during the first 24 h following surgery."2.73Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study. ( Hamidi, S; Khan, ZH; Majedi, H; Miri, M; Nourijelyani, K, 2008)
"Haemodynamic, Toddler, Preschooler, Postoperative Pain Scale (TPPPS) pain score and sedation score values were recorded 30 min after extubation and at hours 2, 4, 6, 12 and 24."2.71Caudal neostigmine for postoperative analgesia in paediatric surgery. ( Karamanlioğlu, B; Kaya, G; Memiş, D; Pamukçu, Z; Süt, N; Turan, A, 2003)
"Neostigmine has been added to local anesthetics for different nerve blocks."2.71Caudal ropivacaine and neostigmine in pediatric surgery. ( Başaran, UN; Karamanlioğlu, B; Memiş, D; Süt, N; Turan, A, 2003)
"Our basic finding was reduction in postoperative pain and consumption of adequate analgesic drugs with intra-articular ketamine, bupivacaine, or neostigmine use."2.71The efficacy of intra-articular ketamine for postoperative analgesia in outpatient arthroscopic surgery. ( Altunkaya, H; Dal, D; Doral, MN; Tetik, O, 2004)
"Monitoring for pain, sedation, postoperative nausea/vomiting, dizziness, and pruritus was performed by anesthesiologists blinded to the study allocation."2.71Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine. ( Acharya, A; Kumar, P; Pan, AK; Rudra, A, 2005)
" The time to first rescue analgesic (minutes) was longer for all patients who received intrathecal morphine combined with 1-5 microg neostigmine (median, 6 h) compared with the control group (median, 3 h) (P < 0."2.71Antinociceptive effect of low-dose intrathecal neostigmine combined with intrathecal morphine following gynecologic surgery. ( Almeida, RA; Lauretti, GR; Mattos, AL, 2003)
"Fentanyl was continued at the designated rate through the initial postoperative phase."2.71Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration. ( Iwakiri, H; Matsukawa, T; Nagata, O; Ozaki, M; Sessler, DI, 2003)
"Neostigmine 500 microg was added in group N, and saline 1 mL in group S."2.70Neostigmine added to lidocaine axillary plexus block for postoperative analgesia. ( Lebrun, T; Mehdaoui, H; Pastureau, F; Van Elstraete, AC, 2001)
"The morphine group had a later onset of postsurgical pain and longer time to first rescue analgesics than the neostigmine group (P <0."2.70Intrathecal bupivacaine with morphine or neostigmine for postoperative analgesia after total knee replacement surgery. ( Chia, YY; Lee, TH; Liu, K; Lo, Y; Tan, PH; Yang, LC, 2001)
"Neostigmine was more effective for somatic pain than visceral pain."2.68The effects of intrathecal neostigmine on somatic and visceral pain: improvement by association with a peripheral anticholinergic. ( Lauretti, GR; Lima, IC, 1996)
"It is essential to find good postoperative pain control strategies that facilitate early mobility, early recovery, and early hospital discharge with minimal side effects on the mother and infant."2.66Strategies of analgesic treatment after cesarean delivery. Current state and new alternatives. ( Arroyo-Fernández, FJ; Calderón Seoane, JE; Torres Morera, LM, 2020)
"Neostigmine and tramadol increase the probability for post-operative nausea or vomiting (PONV)."2.48Bayesian enhanced meta-analysis of post-operative analgesic efficacy of additives for caudal analgesia in children. ( Engelman, E; Marsala, C, 2012)
"Adjuvants are compounds which by themselves have undesirable side-effects or low potency but in combination with opioids allow a reduction of narcotic dosing for postoperative pain control."2.44Useful adjuvants for postoperative pain management. ( Buvanendran, A; Kroin, JS, 2007)
"Neostigmine is a parasympathomimetic agent that has been recently investigated for use as an adjunct analgesic agent in the perioperative and peripartum period."2.43Use of neostigmine in the management of acute postoperative pain and labour pain: a review. ( Gan, TJ; Habib, AS, 2006)
"Clonidine has shown considerable analgesic effect, with minimal adverse effects."2.42Non-narcotic adjuvants may improve the duration and quality of analgesia after knee arthroscopy: a brief review. ( Brill, S; Plaza, M, 2004)
"2."1.35Postoperative analgesia induced by intrathecal neostigmine or bethanechol in rats. ( Dias, TB; Prado, WA, 2009)
"Neuromuscular blockade was maintained with rocuronium (visual train-of-four [TOF] count of 2) and all subjects were reversed with neostigmine at a TOF count of 2-4."1.33Residual paralysis at the time of tracheal extubation. ( Avram, MJ; Franklin, M; Marymont, JH; Murphy, GS; Szokol, JW; Vender, JS, 2005)
"In the plantar foot incision model of postoperative pain there was no gender difference in postoperative mechanical hypersensitivity (von Frey filaments) over four days."1.32Postoperative pain and analgesic responses are similar in male and female Sprague-Dawley rats. ( Buvanendran, A; Kroin, JS; Nagalla, SK; Tuman, KJ, 2003)
"We report the analgesic and adverse effects of intrathecally administered hyperbaric neostigmine, alone or combined with morphine, in two patients suffering from severe lower limb ischaemic pain (group 1), five patients undergoing Caesarean section (group 2) and 19 patients scheduled for orthopaedic surgery (group 3) under spinal anaesthesia."1.30Analgesic and adverse effects of a low dose of intrathecally administered hyperbaric neostigmine alone or combined with morphine in patients submitted to spinal anaesthesia: pilot studies. ( Garcia, LV; Klamt, JG; Prado, WA, 1999)
"Ampullary stenosis was confirmed in all patients who subsequently underwent sphincteroplasty."1.26Duodenoscopy and endoscopic pancreatography in patients with postive morphine prostigmine tests. ( Capobianco, AG; Frager, SH; Gregg, JA; McCartney, AJ; Milano, AF; Santoro, BT; Taddeo, AE, 1977)

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.57)18.7374
1990's15 (17.86)18.2507
2000's45 (53.57)29.6817
2010's17 (20.24)24.3611
2020's4 (4.76)2.80

Authors

AuthorsStudies
Xiong, C1
Han, C1
Lv, H1
Xu, D1
Peng, W1
Zhao, D1
Lan, Z1
Feng, J1
Wang, H1
Peng, L1
Xu, H1
Song, X1
Ashoor, TM1
Zain, EM1
Reyad, MK1
Hasseb, AM1
Esmat, IM1
Arroyo-Fernández, FJ1
Calderón Seoane, JE1
Torres Morera, LM1
Ju, JW1
Kim, HC1
Yoon, S1
Hong, DM1
Park, HP1
Shirmohammadie, M1
Ebrahim Soltani, A1
Arbabi, S1
Nasseri, K1
Kim, NY1
Koh, JC1
Lee, KY1
Kim, SS1
Hong, JH1
Nam, HJ1
Bai, SJ1
Oh, TK1
Ji, E1
Na, HS1
Boon, M1
Martini, CH1
Aarts, LP1
Bevers, RF1
Dahan, A1
Castro, DS1
Leão, P1
Borges, S1
Gomes, L1
Pacheco, M1
Figueiredo, P1
Fyneface-Ogan, S1
Mato, CN1
Tobin, M1
Marucio, RL2
Monteiro, ER1
Moroz, LR1
Fantoni, DT1
Kayalha, H1
Mousavi, Z1
Sadat Barikani, A1
Yaghoobi, S1
Khezri, MB1
Stourac, P1
Adamus, M1
Seidlova, D1
Pavlik, T1
Janku, P1
Krikava, I1
Mrozek, Z1
Prochazka, M1
Klucka, J1
Stoudek, R1
Bartikova, I1
Kosinova, M1
Harazim, H1
Robotkova, H1
Hejduk, K1
Hodicka, Z1
Kirchnerova, M1
Francakova, J1
Obare Pyszkova, L1
Hlozkova, J1
Sevcik, P1
Luna, SP1
Neto, FJ1
Minto, BW1
Hatschbach, E1
Kida, K1
Ohtani, N1
Shoji, K2
Yasui, Y1
Masaki, E2
Gómez-Martínez, ML1
Fernández Garijo, P1
Bustamante Munguira, J1
Gómez Herreras, JI1
Prado, WA4
Dias, TB1
Khan, ZH1
Hamidi, S1
Miri, M1
Majedi, H1
Nourijelyani, K1
Batra, YK3
Rajeev, S1
Panda, NB1
Lokesh, VC1
Rao, KL1
Ledowski, T1
Preuss, J1
Schug, SA1
Karaaslan, K1
Gulcu, N1
Ozturk, H1
Sarpkaya, A1
Colak, C1
Kocoglu, H1
Eisenach, JC5
Yu, D1
Chai, W1
Sun, X1
Yao, L1
Sethi, D1
Wason, R1
Taheri, R1
Shayeghi, S1
Razavi, SS1
Sadeghi, A1
Ghabili, K1
Ghojazadeh, M1
Rouzrokh, M1
Hye, MA1
Masud, KM1
Banik, D2
Haque, MF1
Akhtaruzzaman, KM1
Dadu, S1
Mishra, LS1
Agrawal, M1
Chandola, HC1
Engelman, E1
Marsala, C1
Taspinar, V1
Pala, Y1
Diker, S1
Ornek, HD1
Ozdogan, L1
Akcay, M1
Dikmen, B1
Gogus, N2
Abdulatif, M1
El-Sanabary, M1
Omais, M1
Lauretti, GR10
Paccola, CA2
Almeida, RA1
Mattos, AL2
Turan, A2
Memiş, D2
Başaran, UN1
Karamanlioğlu, B2
Süt, N2
Kaya, G1
Pamukçu, Z2
Iwakiri, H1
Nagata, O1
Matsukawa, T1
Ozaki, M1
Sessler, DI1
Arya, VK1
Mahajan, R3
Chari, P1
Bouderka, MA1
Al-Harrar, R1
Bouaggad, A1
Harti, A1
Tang, J1
Xu, Q1
Ye, T1
Kroin, JS2
Buvanendran, A2
Nagalla, SK1
Tuman, KJ1
Kaya, FN1
Sahin, S1
Owen, MD1
Dal, D1
Tetik, O2
Altunkaya, H1
Doral, MN1
Brill, S1
Plaza, M1
Saito, H1
Matsushima, M1
Almenrader, N2
Passariello, M2
D'Amico, G1
Haiberger, R1
Pietropaoli, P1
Alagol, A1
Calpur, OU1
Usar, PS1
Turan, N1
Murphy, GS1
Szokol, JW1
Marymont, JH1
Franklin, M1
Avram, MJ1
Vender, JS1
Kumar, P1
Rudra, A1
Pan, AK1
Acharya, A1
Frizelle, HP1
Curran, E1
Twomey, C1
MacAdoo, J1
Shorten, G1
Chia, YY2
Chang, TH1
Liu, K4
Chang, HC1
Ko, NH1
Wang, YM1
Kumar, S1
Roelants, F1
Tekin, S1
Topcu, I1
Ekici, NZ1
Caglar, H1
Erincler, T1
Habib, AS1
Gan, TJ1
Bouaziz, H2
Tong, C1
Lima, IC1
Reis, MP4
Klamt, JG3
Azevedo, VM1
Klimscha, W1
Chiari, A1
Lorber, C1
Krenn, K1
Dumitrescu, R1
Agnese, T1
Slullitel, A1
Garcia, IV1
Clarke, PM1
Yang, LC3
Chen, LM1
Wang, CJ1
Buerkle, H1
Pereira, NL3
Chung, CJ1
Kim, JS1
Park, HS1
Chin, YJ1
Hood, DD1
Pfeifer, BL1
Garcia, LV1
Chiari, AI1
de Oliveira, R2
Juliâo, MC2
Paqueron, X1
Bur, ML1
Merle, M1
Laxenaire, MC1
Benhamou, D1
Utsunomiya, N1
Tanaka, M2
Ogawa, Y1
Konomi, H1
Takahata, S1
Nabae, T1
Yokohata, K1
Chijiiwa, K1
Oliveira, AP1
Tsai, TC1
Deng, TY1
Perez, MV1
Tan, PH2
Peng, CH1
Lin, CR1
Lu, CY1
Kirdemir, P1
Ozkoçak, I1
Demir, T1
Nakayama, M1
Ichinose, H1
Nakabayashi, K1
Satoh, O1
Yamamoto, S1
Namiki, A1
Van Elstraete, AC1
Pastureau, F1
Lebrun, T1
Mehdaoui, H1
Lo, Y1
Lee, TH1
Gregg, JA1
Taddeo, AE1
Milano, AF1
McCartney, AJ1
Santoro, BT1
Frager, SH1
Capobianco, AG1
Sheref, SE1
Ikeda, S1
Matsumoto, S1
Yoshimoto, H1
Nakayama, F1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison the Postoperative Quality of Recovery Between Neostigmine and Sugammadex in Elderly Patients Undergoing Trans Pars Plana Vitrectomy With General Anesthesia -Randomized Controlled Trial-[NCT03108989]90 participants (Actual)Interventional2017-02-08Completed
Effect of Deep BLock on Intraoperative Surgical Conditions, Perioperative Hemodynamic Status and Respiratory Parameters Following Reversal With Sugammadex in Patients Undergoing Laparoscopic Renal and Prostate Surgery.[NCT01631149]Phase 424 participants (Actual)Interventional2012-06-30Completed
Effect of Deep Neuromuscular Blockade on Surgical Conditions and Recovery After Robotic Radical Prostatectomy: a Prospective Randomized Study[NCT02513693]Phase 480 participants (Anticipated)Interventional2015-07-31Recruiting
The Effect of Prophylactic Magnesium Use in Pregnant Women on Reversal of Neuromuscular Block With Sugammadex:Evaluation With TOF[NCT05558969]30 participants (Anticipated)Interventional2022-09-28Recruiting
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant[NCT02819089]100 participants (Anticipated)Interventional2016-05-31Recruiting
Comparison of Two Different Anesthetic Techniques on Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position: A Prospective Randomized Clinical Trial[NCT03572517]65 participants (Actual)Interventional2017-09-01Completed
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty: A Randomized, Controlled Trial[NCT05601674]76 participants (Actual)Interventional2022-11-04Completed
Effect of Intravenous Paracetamol in Combination With Caudal Ropivacaine on Quality of Postoperative Recovery in Paediatric Patients Undergoing Hypospadias Repair[NCT03781505]Phase 464 participants (Anticipated)Interventional2019-01-31Recruiting
Residual Curarization and Its Incidence at Tracheal Extubation in China[NCT01871064]1,571 participants (Actual)Observational2012-12-31Completed
A Perspective, Multicentre, Randomized,Blind Study of Residual Curarization Incidence in China[NCT01690338]Phase 46,090 participants (Anticipated)Interventional2012-10-31Recruiting
Comparison of the Effectiveness of the Use of Ropivacaine and Midazolam by Intraarticular vs Epidural Administration on Post-operative Analgesia After Isolated Arthroscopic ACL Reconstruction With Hamstring Autograft.[NCT05078372]Phase 2108 participants (Actual)Interventional2019-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Breathing

"In the recovery room the respiratory rate will be measured continuously using the Respir8 respiratory rate monitor. The data will be recorded on the CRF at 15 min intervals.~Breathing rate units are number of breaths as measured in 1 min.~Comparison by t-test: NS between treatments" (NCT01631149)
Timeframe: Measurements will be made during the stay in the recovery room for an average period of 3 hours

Interventionbreaths per min (Mean)
Moderate/Normal Surgical Block14.5
Deep Surgical Block14.5

Nausea and Vomiting

"Using a yes - no questionnaire, the patients will be asked whether they are nauseated or not or whether they vomited. In fact yes indicates the nr of participants.~No statistical analysis was performed." (NCT01631149)
Timeframe: Measurements will be made during the stay in the operating room for an average period of 3 hours

Interventionparticipants (Number)
Moderate/Normal Surgical Block0
Deep Surgical Block0

Post-operative Pain

"Using a 10 cm visual analogue score pain relief score will be measured. 0 = no pain 10 = most severe pain~No statistical analysis was performed!" (NCT01631149)
Timeframe: measurements are made in the recovery room following surgery for an average prior of 1 hour

Interventionunits on a scale (0-10 cm) (Mean)
Moderate/Normal Surgical Block2.6
Deep Surgical Block2.1

Postoperative Sedation Score

"Using a 5-point sedation scale, sedation levels will be obtained throughout the postoperative period.~0 = wide awake 5= severely sedated, The sedation data were averaged over time." (NCT01631149)
Timeframe: Measurements will be made during the stay in the operating room for an average period of 3 hours

Interventionunits on a scale (0-5) (Mean)
Moderate/Normal Surgical Block2.0
Deep Surgical Block1.3

Surgical Rating Scale

"During the procedure, the surgical condition will be scored by the surgeon using a 5-point surgical rating scale. In order to reduce variability in the surgical rating all surgeries will be performed by one single surgeon. The rating scale will be a 5-point ordinal scale ranging from 1 = poor condition to 5 = optimal surgical conditions. The surgeon will score the condition at 15 minute intervals. In case of a sudden change in surgical conditions additional scores will be added to the case record form. If conditions are poor (score 1 or 2), muscle relaxation will be increased, a score of 1 will be used.~In each subject the scores over time were averaged and a comparison between treatments was performed using a t-test" (NCT01631149)
Timeframe: Measurements will be made during the stay in the operating room for an average period of 3 hours

Interventionunits on a scale (1-5) (Mean)
Moderate/Normal Surgical Block4
Deep Surgical Block4.7

Reviews

7 reviews available for neostigmine and Pain, Postoperative

ArticleYear
Comparison of adjuvant pharmaceuticals for caudal block in pediatric lower abdominal and urological surgeries: A network meta-analysis.
    Journal of clinical anesthesia, 2022, Volume: 81

    Topics: Analgesics; Anesthetics, Local; Child; Dexamethasone; Dexmedetomidine; Humans; Neostigmine; Network

2022
Strategies of analgesic treatment after cesarean delivery. Current state and new alternatives.
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:3

    Topics: Acetaminophen; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epi

2020
Bayesian enhanced meta-analysis of post-operative analgesic efficacy of additives for caudal analgesia in children.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:7

    Topics: Adjuvants, Anesthesia; Adolescent; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Anesthet

2012
Non-narcotic adjuvants may improve the duration and quality of analgesia after knee arthroscopy: a brief review.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:10

    Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthroscop

2004
The use of neuraxial adjuvant drugs (neostigmine, clonidine) in obstetrics.
    Current opinion in anaesthesiology, 2006, Volume: 19, Issue:3

    Topics: Analgesia, Obstetrical; Analgesics; Cesarean Section; Cholinesterase Inhibitors; Clonidine; Female;

2006
Use of neostigmine in the management of acute postoperative pain and labour pain: a review.
    CNS drugs, 2006, Volume: 20, Issue:10

    Topics: Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Intravenous; Anesthes

2006
Useful adjuvants for postoperative pain management.
    Best practice & research. Clinical anaesthesiology, 2007, Volume: 21, Issue:1

    Topics: Amines; Clonidine; Cyclohexanecarboxylic Acids; Dexamethasone; Excitatory Amino Acid Antagonists; Ga

2007

Trials

58 trials available for neostigmine and Pain, Postoperative

ArticleYear
Effects of Thoracic Paravertebral Block on Postoperative Analgesia in Infants and Small Children undergoing Ultra-Fast Track Cardiac Anesthesia: A Randomized Controlled Trial.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Anesthesia, Cardiac Procedures; Blood Glucose; Child; Humans; Infant;

2023
Ultrasound-guided Techniques for Perioperative Analgesia in Pediatric Lower Abdominal Surgeries: Quadratus Lumborum Block with Bupivacaine versus Caudal Bupivacaine and Neostigmine.
    Pain physician, 2023, Volume: 26, Issue:2

    Topics: Acetaminophen; Analgesia; Analgesics; Anesthetics, Local; Bupivacaine; Child; Humans; Neostigmine; P

2023
Effects of calcium chloride coadministered with neostigmine on neuromuscular blockade recovery: A double-blind randomised study.
    European journal of anaesthesiology, 2017, Volume: 34, Issue:9

    Topics: Adult; Aged; Anesthesia, General; Calcium Chloride; Cholinesterase Inhibitors; Delayed Emergence fro

2017
A randomized-controlled, double-blind study to evaluate the efficacy of caudal midazolam, ketamine and neostigmine as adjuvants to bupivacaine on postoperative analgesic in children undergoing lower abdominal surgery.
    Acta bio-medica : Atenei Parmensis, 2019, 01-15, Volume: 89, Issue:4

    Topics: Abdomen; Analgesics; Anesthesia, Caudal; Anesthetics; Bupivacaine; Child, Preschool; Double-Blind Me

2019
Influence of reversal of neuromuscular blockade with sugammadex or neostigmine on postoperative quality of recovery following a single bolus dose of rocuronium: A prospective, randomized, double-blinded, controlled study.
    Journal of clinical anesthesia, 2019, Volume: 57

    Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Double-Blind Method; Female; Humans; Male; Mi

2019
Effect of variations in depth of neuromuscular blockade on rating of surgical conditions by surgeon and anesthesiologist in patients undergoing laparoscopic renal or prostatic surgery (BLISS trial): study protocol for a randomized controlled trial.
    Trials, 2013, Mar-01, Volume: 14

    Topics: Academic Medical Centers; Androstanols; Anesthesia Department, Hospital; Atracurium; Atropine; Attit

2013
Effect of variations in depth of neuromuscular blockade on rating of surgical conditions by surgeon and anesthesiologist in patients undergoing laparoscopic renal or prostatic surgery (BLISS trial): study protocol for a randomized controlled trial.
    Trials, 2013, Mar-01, Volume: 14

    Topics: Academic Medical Centers; Androstanols; Anesthesia Department, Hospital; Atracurium; Atropine; Attit

2013
Effect of variations in depth of neuromuscular blockade on rating of surgical conditions by surgeon and anesthesiologist in patients undergoing laparoscopic renal or prostatic surgery (BLISS trial): study protocol for a randomized controlled trial.
    Trials, 2013, Mar-01, Volume: 14

    Topics: Academic Medical Centers; Androstanols; Anesthesia Department, Hospital; Atracurium; Atropine; Attit

2013
Effect of variations in depth of neuromuscular blockade on rating of surgical conditions by surgeon and anesthesiologist in patients undergoing laparoscopic renal or prostatic surgery (BLISS trial): study protocol for a randomized controlled trial.
    Trials, 2013, Mar-01, Volume: 14

    Topics: Academic Medical Centers; Androstanols; Anesthesia Department, Hospital; Atracurium; Atropine; Attit

2013
Sugammadex reduces postoperative pain after laparoscopic bariatric surgery: a randomized trial.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2014, Volume: 24, Issue:5

    Topics: Adult; Bariatric Surgery; Female; gamma-Cyclodextrins; Humans; Laparoscopy; Male; Neostigmine; Obesi

2014
A comparative study between caudal bupivacaine and bupivacaine co-administered with neostigmine for postoperative analgesia in children.
    The Nigerian postgraduate medical journal, 2014, Volume: 21, Issue:1

    Topics: Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Female; Humans; Infa

2014
Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in dogs undergoing orthopedic surgery of the pelvic limbs.
    American journal of veterinary research, 2014, Volume: 75, Issue:11

    Topics: Analgesia; Analgesia, Epidural; Analgesics, Opioid; Animals; Dogs; Drug Therapy, Combination; Female

2014
THE EFFECTS OF INTRATHECAL NEOSTIGMINE ADDED TO BUPIVACAINE ON POSTOPERATIVE ANALGESIC REQUIREMENT IN PATIENTS UNDERGOING LOWER LIMB ORTHOPEDIC SURGERY.
    Middle East journal of anaesthesiology, 2015, Volume: 23, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Lower Extremity;

2015
Low-Dose or High-Dose Rocuronium Reversed with Neostigmine or Sugammadex for Cesarean Delivery Anesthesia: A Randomized Controlled Noninferiority Trial of Time to Tracheal Intubation and Extubation.
    Anesthesia and analgesia, 2016, Volume: 122, Issue:5

    Topics: Adolescent; Adult; Androstanols; Anesthesia, General; Anesthesia, Obstetrical; Antidotes; Cesarean S

2016
Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs.
    American journal of veterinary research, 2008, Volume: 69, Issue:7

    Topics: Analgesia, Epidural; Animals; Dogs; Female; Hysterectomy; Morphine; Neostigmine; Ovariectomy; Pain M

2008
Postoperative pain status after intraoperative systemic dexmedetomidine and epidural neostigmine in patients undergoing lower abdominal surgery.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:11

    Topics: Abdomen; Adult; Amides; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthesia, General; Dexmedet

2008
Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study.
    Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:6

    Topics: Adult; Analgesics, Opioid; Cholinesterase Inhibitors; Diskectomy; Double-Blind Method; Female; Human

2008
Intrathecal neostigmine with bupivacaine for infants undergoing lower abdominal and urogenital procedures: dose response.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:4

    Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Hemodynamics;

2009
Two different doses of caudal neostigmine co-administered with levobupivacaine produces analgesia in children.
    Paediatric anaesthesia, 2009, Volume: 19, Issue:5

    Topics: Analgesia; Anesthesia, Caudal; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child, Presch

2009
Intravenous regional anesthesia using lidocaine and neostigmine for upper limb surgery.
    Journal of clinical anesthesia, 2010, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Combined; Anestheti

2010
Efficacy of bupivacaine-neostigmine and bupivacaine-tramadol in caudal block in pediatric inguinal herniorrhaphy.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:9

    Topics: Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Conscious Sedation; Do

2010
Intrathecal neostigmine for postoperatrive analgesia in caesarean section.
    Mymensingh medical journal : MMJ, 2010, Volume: 19, Issue:4

    Topics: Adult; Analgesia, Obstetrical; Cesarean Section; Double-Blind Method; Female; Humans; Injections, Sp

2010
Comparative clinical study of effect of neostigmine and ketamine for postoperative analgesia.
    Journal of the Indian Medical Association, 2011, Volume: 109, Issue:5

    Topics: Adolescent; Adult; Analgesia, Epidural; Analgesics; Anesthetics, Local; Bupivacaine; Cholinesterase

2011
Pre-emptive analgesic and haemodynamic efficacy of combined spinal-epidural neostigmine delivery.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:4

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Anesthesia, Conduction; Anesthesia, Spina

2012
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D

2002
Epidural morphine and neostigmine for postoperative analgesia after orthopedic surgery.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Cholinesterase Inhibitors; Double-Blind Method

2002
Antinociceptive effect of low-dose intrathecal neostigmine combined with intrathecal morphine following gynecologic surgery.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Dose-Response Relationship, Drug; Double-Blind Method

2003
Caudal ropivacaine and neostigmine in pediatric surgery.
    Anesthesiology, 2003, Volume: 98, Issue:3

    Topics: Amides; Anesthesia, Caudal; Child; Child, Preschool; Humans; Infant; Neostigmine; Pain, Postoperativ

2003
Caudal neostigmine for postoperative analgesia in paediatric surgery.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:4

    Topics: Anesthesia, Caudal; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Child, Preschool; Double

2003
Effect-site concentration of propofol for recovery of consciousness is virtually independent of fentanyl effect-site concentration.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:6

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Atropine; Bradycardia; Female; Fentanyl

2003
Dose response study of caudal neostigmine for postoperative analgesia in paediatric patients undergoing genitourinary surgery.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Caudal; Child; Child, Preschool; Cholinesterase

2003
[Neostigmine added to bupivacaine in axillary plexus block: which benefit?].
    Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:6

    Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bupivacaine; Fem

2003
[Prevention and release of epidural-morphine-induced urinary retention with phenoxybenzamine and neostigmine].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2000, Volume: 22, Issue:6

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Analgesia, Epidural; Analgesics, Opioid; Drug Thera

2000
Epidural neostigmine produces analgesia but also sedation in women after cesarean delivery.
    Anesthesiology, 2004, Volume: 100, Issue:2

    Topics: Adult; Analgesia; Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Cesarean Section; Fema

2004
The efficacy of intra-articular ketamine for postoperative analgesia in outpatient arthroscopic surgery.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2004, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics; Analysis of Variance; Anesthetics, Lo

2004
Postoperative analgesic effect of epidural neostigmine and plasma cortisol and IL-6 responses.
    Journal of clinical anesthesia, 2004, Volume: 16, Issue:7

    Topics: Adult; Analgesia, Epidural; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Double-Blin

2004
Caudal additives for postoperative pain management in children: S(+)-ketamine and neostigmine.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:2

    Topics: Analgesics; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation;

2005
Intraarticular analgesia after arthroscopic knee surgery: comparison of neostigmine, clonidine, tenoxicam, morphine and bupivacaine.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2005, Volume: 13, Issue:8

    Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Bupivacaine; Cholinesterase Inhibitors; Clonidi

2005
Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Intravenous; Anest

2005
Nausea and vomiting after cataract surgery: does neostigmine have an emetic effect?
    European journal of anaesthesiology, 2005, Volume: 22, Issue:7

    Topics: Aged; Anesthesia, General; Cataract Extraction; Cholinesterase Inhibitors; Electric Stimulation; Fem

2005
The efficacy of thoracic epidural neostigmine infusion after thoracotomy.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Adult; Aged; Analgesia, Epidural; Double-Blind Method; Female; Humans; Male; Middle Aged; Neostigmin

2006
Comparison of analgesic activity of the addition to neostigmine and fentanyl to bupivacaine in postoperative epidural analgesia.
    Saudi medical journal, 2006, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Analgesia, Epidural; Analgesics; Anesthetics, Local; Bupivacaine; Cholinest

2006
The effects of intrathecal neostigmine on somatic and visceral pain: improvement by association with a peripheral anticholinergic.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Adult; Analgesia; Analgesics; Butylscopolammonium Bromide; Cholinergic Antagonists; Double-Blind Met

1996
Dose-response study of intrathecal morphine versus intrathecal neostigmine, their combination, or placebo for postoperative analgesia in patients undergoing anterior and posterior vaginoplasty.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:6

    Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics, Inhalation; Dose-Response Relationship, Dru

1996
Postoperative analgesic effect of intrathecal neostigmine and its influence on spinal anaesthesia.
    Anaesthesia, 1997, Volume: 52, Issue:6

    Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Cholinesterase Inhibitors; Double-Blind Method; Femal

1997
Intrathecal neostigmine.
    Anaesthesia, 1997, Volume: 52, Issue:10

    Topics: Cholinesterase Inhibitors; Humans; Nausea; Neostigmine; Pain, Postoperative; Vomiting

1997
Postoperative analgesia by intra-articular neostigmine in patients undergoing knee arthroscopy.
    Anesthesiology, 1998, Volume: 88, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroscopy; Cholinesterase Inhibitors; Do

1998
Combined intrathecal fentanyl and neostigmine: therapy for postoperative abdominal hysterectomy pain relief.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:4

    Topics: Adult; Analgesics, Opioid; Analysis of Variance; Drug Therapy, Combination; Female; Fentanyl; Humans

1998
The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Hu

1998
A multi-center study of intrathecal neostigmine for analgesia following vaginal hysterectomy.
    Anesthesiology, 1998, Volume: 89, Issue:4

    Topics: Adult; Aged; Analgesics; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Double-Blind M

1998
Study of three different doses of epidural neostigmine coadministered with lidocaine for postoperative analgesia.
    Anesthesiology, 1999, Volume: 90, Issue:6

    Topics: Adult; Analgesia, Epidural; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Com

1999
No enhancement of sensory and motor blockade by neostigmine added to mepivacaine axillary plexus block.
    Anesthesiology, 1999, Volume: 91, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Cholinesterase Inhibitors; Double-Blind Method;

1999
Transdermal nitroglycerine enhances spinal neostigmine postoperative analgesia following gynecological surgery.
    Anesthesiology, 2000, Volume: 93, Issue:4

    Topics: Administration, Cutaneous; Analgesia; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cholinest

2000
Efficacy of intrathecal neostigmine for the relief of postinguinal hemiorrhaphy pain.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:9

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Cholinesterase Inhibitors; Hernia, In

2000
Postoperative analgesia by intraarticular and epidural neostigmine following knee surgery.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:6

    Topics: Adult; Aged; Analgesia, Epidural; Double-Blind Method; Female; Humans; Injections, Intra-Articular;

2000
The effect of dexamethasone on postoperative pain and emesis after intrathecal neostigmine.
    Anesthesia and analgesia, 2001, Volume: 92, Issue:1

    Topics: Adult; Anesthesia, Spinal; Anesthetics, Local; Anti-Inflammatory Agents; Dexamethasone; Double-Blind

2001
Comparison of postoperative analgesic effects of preemptively used epidural ketamine and neostigmine.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:7

    Topics: Adult; Aged; Analgesia, Epidural; Female; Humans; Ketamine; Male; Middle Aged; Neostigmine; Pain, Po

2000
Analgesic effect of epidural neostigmine after abdominal hysterectomy.
    Journal of clinical anesthesia, 2001, Volume: 13, Issue:2

    Topics: Analgesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Diclofenac;

2001
Neostigmine added to lidocaine axillary plexus block for postoperative analgesia.
    European journal of anaesthesiology, 2001, Volume: 18, Issue:4

    Topics: Aged; Anesthetics, Local; Blood Pressure; Cholinesterase Inhibitors; Double-Blind Method; Female; He

2001
Intrathecal bupivacaine with morphine or neostigmine for postoperative analgesia after total knee replacement surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:6

    Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Cross-Ov

2001
Pattern of CNS recovery following reversal of neuromuscular blockade. Comparison of atropine and glycopyrrolate.
    British journal of anaesthesia, 1985, Volume: 57, Issue:2

    Topics: Adult; Atropine; Brain; Female; Glycopyrrolate; Humans; Male; Middle Aged; Neostigmine; Neuromuscula

1985

Other Studies

19 other studies available for neostigmine and Pain, Postoperative

ArticleYear
The effect of neuromuscular reversal agent on postoperative pain after laparoscopic gastric cancer surgery: Comparison between the neostigmine and sugammadex.
    Medicine, 2019, Volume: 98, Issue:26

    Topics: Adult; Aged; Analgesics; Female; Humans; Laparoscopy; Length of Stay; Male; Middle Aged; Neostigmine

2019
[On "Ventricular fibrillation in a patient with type I Brugada syndrome"].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:8

    Topics: Brugada Syndrome; Contraindications; Defibrillators; Electric Countershock; Humans; Hypokalemia; Mal

2008
Postoperative analgesia induced by intrathecal neostigmine or bethanechol in rats.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:7

    Topics: Analgesia; Animals; Bethanechol; Injections, Spinal; Male; Neostigmine; Pain Measurement; Pain, Post

2009
The effects of neostigmine and glycopyrrolate on skin conductance as a measure of pain.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:9

    Topics: Adult; Cholinesterase Inhibitors; Female; Galvanic Skin Response; Glycopyrrolate; Humans; Male; Musc

2009
Epidural neostigmine: will it replace lipid soluble opioids for postoperative and labor analgesia?
    Anesthesia and analgesia, 2009, Volume: 109, Issue:2

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cholinesterase Inhibitors; F

2009
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Caudal neostigmine in children.
    British journal of anaesthesia, 2003, Volume: 91, Issue:5

    Topics: Analgesics, Non-Narcotic; Anesthesia, Caudal; Child; Cholinesterase Inhibitors; Humans; Neostigmine;

2003
Postoperative pain and analgesic responses are similar in male and female Sprague-Dawley rats.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2003, Volume: 50, Issue:9

    Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cholinesterase Inhibito

2003
Residual paralysis at the time of tracheal extubation.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Cholinesterase Inhibito

2005
Residual paralysis at the time of tracheal extubation.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Cholinesterase Inhibito

2005
Residual paralysis at the time of tracheal extubation.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Cholinesterase Inhibito

2005
Residual paralysis at the time of tracheal extubation.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Cholinesterase Inhibito

2005
Adjuncts to caudal blockade in children.
    British journal of anaesthesia, 2006, Volume: 96, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, Caudal; Cholinesterase Inhibitors; Humans; Neostigmine; Pain, Pos

2006
Adjuncts to caudal blockade in children.
    British journal of anaesthesia, 2006, Volume: 96, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, Caudal; Cholinesterase Inhibitors; Humans; Neostigmine; Pain, Pos

2006
Postoperative analgesia from intrathecal neostigmine in sheep.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:6

    Topics: Analgesia, Epidural; Animals; Female; Neostigmine; Pain Measurement; Pain, Postoperative; Pirenzepin

1995
Intravenous ketamine or fentanyl prolongs postoperative analgesia after intrathecal neostigmine.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Dissociative; Anesthetics, Intraveno

1996
Additives in neuraxial anesthesia: opioids, alpha-2 adrenergic agonists, and neostigmine as a possible future drug for perioperative pain management.
    Acta anaesthesiologica Scandinavica. Supplementum, 1996, Volume: 109

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesia, E

1996
Analgesic and adverse effects of a low dose of intrathecally administered hyperbaric neostigmine alone or combined with morphine in patients submitted to spinal anaesthesia: pilot studies.
    Anaesthesia, 1999, Volume: 54, Issue:1

    Topics: Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Cesarean Section; Cholinesterase Inh

1999
Intrathecal adenosine: interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative hypersensitivity.
    Anesthesiology, 1999, Volume: 90, Issue:5

    Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Clonidine; Disease Models, Animal; Dose-Response Relat

1999
Pain associated with phase III of the duodenal migrating motor complex in patients with postcholecystectomy biliary dyskinesia.
    Gastrointestinal endoscopy, 2000, Volume: 51, Issue:5

    Topics: Adult; Aged; Biliary Dyskinesia; Ceruletide; Duodenum; Humans; Injections, Intramuscular; Manometry;

2000
Duodenoscopy and endoscopic pancreatography in patients with postive morphine prostigmine tests.
    American journal of surgery, 1977, Volume: 134, Issue:3

    Topics: Adolescent; Adult; Biliary Tract Diseases; Cholangiography; Cholecystectomy; Chronic Disease; Cicatr

1977
Manometric diagnosis of sphincter of Oddi spasm as a cause of postcholecystectomy pain and the treatment by endoscopic sphincterotomy.
    Annals of surgery, 1985, Volume: 202, Issue:6

    Topics: Adult; Ampulla of Vater; Cholecystectomy; Common Bile Duct Diseases; Female; Humans; Male; Manometry

1985