neostigmine has been researched along with Pain, Intractable in 2 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "48 terminal cancer patients suffering from chronic pain." | 2.69 | Low doses of epidural ketamine or neostigmine, but not midazolam, improve morphine analgesia in epidural terminal cancer pain therapy. ( Gomes, JM; Lauretti, GR; Pereira, NL; Reis, MP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mercadante, S | 1 |
| Serretta, R | 1 |
| Sapio, M | 1 |
| Villari, P | 1 |
| Calderone, L | 1 |
| Lauretti, GR | 1 |
| Gomes, JM | 1 |
| Reis, MP | 1 |
| Pereira, NL | 1 |
1 trial available for neostigmine and Pain, Intractable
| Article | Year |
|---|---|
Low doses of epidural ketamine or neostigmine, but not midazolam, improve morphine analgesia in epidural terminal cancer pain therapy.
Topics: Adult; Aged; Analgesia, Epidural; Double-Blind Method; Drug Synergism; Female; Humans; Ketamine; Mal | 1999 |
1 other study available for neostigmine and Pain, Intractable
| Article | Year |
|---|---|
When all else fails: stepwise multiple solutions for a complex cancer pain syndrome.
Topics: Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholinesterase Inhibitors; Cl | 1999 |