Page last updated: 2024-10-31

neostigmine and Obesity

neostigmine has been researched along with Obesity in 9 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to compare neostigmine-induced reversal of vecuronium in normal weight, overweight and obese female patients."7.73Neostigmine-induced reversal of vecuronium in normal weight, overweight and obese female patients. ( Masaki, G; Ogawa, S; Suzuki, T, 2006)
"Compared with neostigmine, sugammadex can reduce the incidence and severity of PONV, increase postoperative water intake, and shorten the time to first flatus in bariatric patients during postoperative inpatient hospitalization, which may play a pivotal role in enhanced recovery."5.69Use of sugammadex is associated with reduced incidence and severity of postoperative nausea and vomiting in adult patients with obesity undergoing laparoscopic bariatric surgery: a post-hoc analysis. ( Chen, D; Ding, X; Gui, B; Liang, H; Wang, Y; Zhao, C; Zhu, X, 2023)
"A single gene deletion causes lack of leptin and obesity in B6."3.75Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice. ( Baghdoyan, HA; Lydic, R; Wang, W, 2009)
"The purpose of this study was to compare neostigmine-induced reversal of vecuronium in normal weight, overweight and obese female patients."3.73Neostigmine-induced reversal of vecuronium in normal weight, overweight and obese female patients. ( Masaki, G; Ogawa, S; Suzuki, T, 2006)
"To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time."3.70Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998)
"Metformin treatment normalized the cholinergic response, which involved mostly the M3 muscarinic acetylcholine receptor (M3 mAChR) in pancreatic beta-cells."1.62Metformin Improves Autonomic Nervous System Imbalance and Metabolic Dysfunction in Monosodium L-Glutamate-Treated Rats. ( Alves, VS; Barella, LF; de Castro Prado, MAA; de Freitas Mathias, PC; de Moraes, AMP; de Oliveira, JC; de Sant Anna, JR; Francisco, FA; Franco, CCDS; Gomes, RM; Malta, A; Martins, IP; Matiusso, CCI; Miranda, RA; Moreira, VM; Pavanello, A; Prates, KV; Previate, C; Ribeiro, TA; Saavedra, LPJ; Tófolo, LP; Trombini, AB; Vieira, E, 2021)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Ding, X1
Zhu, X1
Zhao, C1
Chen, D1
Wang, Y1
Liang, H1
Gui, B1
Franco, CCDS1
Previate, C1
Trombini, AB1
Miranda, RA1
Barella, LF1
Saavedra, LPJ1
de Oliveira, JC1
Prates, KV1
Tófolo, LP1
Ribeiro, TA1
Pavanello, A1
Malta, A1
Martins, IP1
Moreira, VM1
Matiusso, CCI1
Francisco, FA1
Alves, VS1
de Moraes, AMP1
de Sant Anna, JR1
de Castro Prado, MAA1
Gomes, RM1
Vieira, E1
de Freitas Mathias, PC2
Wang, W1
Baghdoyan, HA2
Lydic, R2
DAWSON, GR1
Douglas, CL1
Bowman, GN1
Suzuki, T1
Masaki, G1
Ogawa, S1
Baggot, MG1
Grassiolli, S1
Gravena, C1
Kirkegaard-Nielsen, H1
Lindholm, P1
Petersen, HS1
Severinsen, IK1

Trials

1 trial available for neostigmine and Obesity

ArticleYear
Use of sugammadex is associated with reduced incidence and severity of postoperative nausea and vomiting in adult patients with obesity undergoing laparoscopic bariatric surgery: a post-hoc analysis.
    BMC anesthesiology, 2023, 05-15, Volume: 23, Issue:1

    Topics: Adult; Antiemetics; Bariatric Surgery; Flatulence; Humans; Incidence; Laparoscopy; Neostigmine; Obes

2023

Other Studies

8 other studies available for neostigmine and Obesity

ArticleYear
Metformin Improves Autonomic Nervous System Imbalance and Metabolic Dysfunction in Monosodium L-Glutamate-Treated Rats.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Acetylcholine; Animals; Autonomic Nervous System; Glucose; Hypoglycemic Agents; Insulin-Secreting Ce

2021
Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice.
    The journal of pain, 2009, Volume: 10, Issue:8

    Topics: Acetylcholine; Adenosine; Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Hot T

2009
A CASE OF POST-OPERATIVE APNOEA RESPONDING TO INTRAVENOUS SODIUM BICARBONATE INFUSION.
    The Medical journal of Australia, 1964, Apr-04, Volume: 1

    Topics: Acidosis; Apnea; Atropine; Bicarbonates; Bis-Trimethylammonium Compounds; Gallamine Triethiodide; Hu

1964
C57BL/6J and B6.V-LEPOB mice differ in the cholinergic modulation of sleep and breathing.
    Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 98, Issue:3

    Topics: Acetylcholine; Animals; Arousal; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug;

2005
Neostigmine-induced reversal of vecuronium in normal weight, overweight and obese female patients.
    British journal of anaesthesia, 2006, Volume: 97, Issue:2

    Topics: Adult; Body Mass Index; Body Weight; Cholinesterase Inhibitors; Female; Humans; Middle Aged; Neostig

2006
Endo-abdominal hypertension complicating pregnancy & fetal development.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Abdomen; Female; Fetal Development; Humans; Hypertension; Ileus; Male; Neostigmine; Obesity; Parasym

2006
Muscarinic M2 receptor is active on pancreatic islets from hypothalamic obese rat.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Acetylcholine; Animals; Animals, Newborn; Diamines; Glucose Tolerance Test; Hypothalamus; In Vitro T

2007
Antagonism of atracurium-induced block in obese patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:1

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight;

1998