neostigmine has been researched along with Labor Pain in 4 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neostigmine is a parasympathomimetic agent that has been recently investigated for use as an adjunct analgesic agent in the perioperative and peripartum period." | 6.43 | Use of neostigmine in the management of acute postoperative pain and labour pain: a review. ( Gan, TJ; Habib, AS, 2006) |
| "To evaluate the quality of analgesia with epidural neostigmine and clonidine, added to initial spinal analgesia, and to test the hypothesis that the incidence of breakthrough pain could be reduced and patient satisfaction improved." | 5.19 | Epidural neostigmine and clonidine improves the quality of combined spinal epidural analgesia in labour: a randomised, double-blind controlled trial. ( Boogmans, T; Devroe, S; Roofthooft, E; Valkenborgh, T; Van de Velde, M; Vertommen, J, 2014) |
| "Epidural administration of neostigmine and clonidine, following the spinal injection of local anesthetic, has a stronger analgesic effect in managing labor pain and reduces hourly anesthetic consumption." | 4.91 | Effects of epidural neostigmine and clonidine in labor analgesia: a systematic review and meta-analysis. ( Xu, MJ; Zhang, N, 2015) |
| "Neostigmine is a parasympathomimetic agent that has been recently investigated for use as an adjunct analgesic agent in the perioperative and peripartum period." | 2.43 | Use of neostigmine in the management of acute postoperative pain and labour pain: a review. ( Gan, TJ; Habib, AS, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boogmans, T | 1 |
| Vertommen, J | 1 |
| Valkenborgh, T | 1 |
| Devroe, S | 1 |
| Roofthooft, E | 1 |
| Van de Velde, M | 1 |
| Zhang, N | 1 |
| Xu, MJ | 1 |
| Roelants, F | 1 |
| Lavand'homme, PM | 1 |
| Mercier-Fuzier, V | 1 |
| Habib, AS | 1 |
| Gan, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Clinical Trial Comparing Programed Intermittent Epidural Boluses (PIEB) Versus Patient Controlled Epidural Analgesia (PCEA) With Epidural or Combined Spinal-epidural (CSE) Technique[NCT02768272] | Phase 4 | 240 participants (Actual) | Interventional | 2016-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for neostigmine and Labor Pain
| Article | Year |
|---|---|
Effects of epidural neostigmine and clonidine in labor analgesia: a systematic review and meta-analysis.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Apgar Score; Clonidine; Delivery, | 2015 |
Use of neostigmine in the management of acute postoperative pain and labour pain: a review.
Topics: Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Intravenous; Anesthes | 2006 |
2 trials available for neostigmine and Labor Pain
| Article | Year |
|---|---|
Epidural neostigmine and clonidine improves the quality of combined spinal epidural analgesia in labour: a randomised, double-blind controlled trial.
Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthesi | 2014 |
Epidural administration of neostigmine and clonidine to induce labor analgesia: evaluation of efficacy and local anesthetic-sparing effect.
Topics: Anesthesia, Epidural; Anesthetics, Local; Clonidine; Drug Therapy, Combination; Female; Humans; Labo | 2005 |