Page last updated: 2024-10-31

neostigmine and Intestinal Obstruction

neostigmine has been researched along with Intestinal Obstruction in 46 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

Research Excerpts

Excerpt	Relevance	Reference
"To investigate the feasibility of using a revised major purgative decoction in combination with nasointestinal decompression for the treatment of intestinal paralysis."	2.80	Treatment of Intestinal Paralysis Using Revised Major Purgative Decoction Combined with Nasointestinal Decompression: Experience with 31 Patients. ( Dechun, L; Guoqing, S; Hongtao, D; Ruihong, L; Wei, L, 2015)
"Electroacupuncture combined with acupoint injection has a satisfied therapeutic effect for treatment of EPISBO."	2.75	[Clinical observation on electroacupuncture combined with acupoint injection for treatment of early postoperative inflammatory intestinal obstruction]. ( Ding, KY; Guan, J; Shen, LP, 2010)
" Dosage of drugs influencing peristalsis is facilitated."	1.28	[Computer-assisted drug therapy of incomplete ileus]. ( Geissler, N; Heymann, H; Jung, D, 1989)

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (73.91)	18.7374
1990's	4 (8.70)	18.2507
2000's	5 (10.87)	29.6817
2010's	3 (6.52)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ruihong, L	1
Dechun, L	1
Guoqing, S	1
Hongtao, D	1
Wei, L	1
Reeves, M	1
Frizelle, F	1
Wakeman, C	1
Parker, C	1
Shen, LP	1
Guan, J	1
Ding, KY	1
Kurtzman, TL	1
Borowitz, SM	1
BREINE, U	1
HEDENBERG, I	1
LILJEDAHL, SO	1
VAL'TER, VG	1
CHICHKOV, IuF	1
SHEPTUKHINA, EM	1
WEINGAERTNER, L	1
REAM, CR	1
MARGGRAF, W	1
HONDA, M	1
TAKESHIGE, S	1
ISHIKAWA, F	1
TOYAMA, F	1
HELBIG, D	1
KOZMA, JJ	1
Penner, RM	1
Jacka, MJ	1
Brindley, PG	1
Neely, J	2
Catchpole, BN	1
Dahlgren, S	1
Thorén, L	1
Prihoda, M	1
Flatt, A	1
Summers, RW	3
Grund, KE	1
Ruf, W	1
Suehiro, G	1
Suehiro, A	1
McNamara, JJ	1
Ruwart, MJ	1
Klepper, MS	1
Rush, BD	1
Orlando, E	1
Finelli, F	1
Colla, M	1
Giotto, E	1
Terragni, P	1
Olivero, G	1
García-Olmo, DC	1
García-Rivas, M	1
García-Olmo, D	1
Daaboul, B	1
Eaker, EY	1
Loffeld, RJ	1
Isbister, GK	1
Oakley, P	1
Whyte, I	1
Dawson, A	1
Althausen, PL	1
Gupta, MC	1
Benson, DR	1
Jones, DA	1
Leonardis, G	1
Ciammitti, B	1
Splendiani, G	1
Champault, G	1
Wiesmeier, R	1
von Sommoggy, S	1
Heinkelmann, W	1
Birk, M	1
Blümel, G	1
Sullivan, MA	1
Snape, WJ	1
Matarazzo, SA	1
Petrokubi, RJ	1
Jeffries, G	1
Cohen, S	1
Dauchel, J	1
Schang, JC	1
Kachelhoffer, J	1
Eloy, R	1
Grenier, JF	1
Constable, PD	1
Muir, WW	1
Freeman, L	1
Hoffsis, GF	1
St Jean, G	1
Welker, FH	1
Geissler, N	1
Jung, D	1
Heymann, H	1
Gómez Gámez, A	1
Sánchez de Badajoz, E	1
García Caballero, M	1
Gutstein Feldman, D	1
Vara Thorbeck, C	1
Hallerbäck, B	1
Ander, S	1
Glise, H	1
Tseng, J	1
Furness, JB	1
Costa, M	1
Daggett, PR	1
Staib, I	1
Kent, TH	2
Heimbach, DM	1
Crout, JR	1
Mieny, CJ	1
Cooke, PA	1
Solomon, H	1
Maldonado, JE	1
Gregg, JA	1
Green, PA	1
Brown, AL	1
Osborne, JW	1
Catchpole, B	1
Klein, N	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery[NCT02056405]			Phase 4	90 participants (Anticipated)	Interventional	2015-12-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for neostigmine and Intestinal Obstruction

Article	Year
Adynamic ileus, its pathogenesis and treatment. Medical biology, 1974, Volume: 52, Issue:2 Topics: Bethanechol Compounds; Chlorpromazine; Ganglia, Autonomic; Gastrointestinal Motility; Guanethidine;	1974

Trials

7 trials available for neostigmine and Intestinal Obstruction

Article	Year
Treatment of Intestinal Paralysis Using Revised Major Purgative Decoction Combined with Nasointestinal Decompression: Experience with 31 Patients. Cell biochemistry and biophysics, 2015, Volume: 73, Issue:2 Topics: Abdomen; Adult; Aged; Cathartics; Decompression; Female; Flatulence; Fluoroscopy; Humans; Intestinal	2015
[Clinical observation on electroacupuncture combined with acupoint injection for treatment of early postoperative inflammatory intestinal obstruction]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2010, Volume: 30, Issue:1 Topics: Acupuncture Points; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Electroacupuncture; F	2010
Best evidence in critical care medicine: medical therapy of acute colonic pseudo-obstruction: a moving experience. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:5 Topics: Acute Disease; Colonic Diseases; Critical Care; Double-Blind Method; Humans; Intestinal Obstruction;	2005
[A double-blind study of neostigmine versus placebo in paralytic ileus as a result of surgical interventions]. Minerva chirurgica, 1994, Volume: 49, Issue:5 Topics: Administration, Intranasal; Adult; Aged; Analysis of Variance; Cholecystectomy; Double-Blind Method;	1994
The use of neostigmine to treat postoperative ileus in orthopedic spinal patients. Journal of spinal disorders, 2001, Volume: 14, Issue:6 Topics: Adolescent; Adult; Female; Humans; Intestinal Obstruction; Male; Middle Aged; Neostigmine; Orthopedi	2001
Effect of combined blockade of beta-adrenoceptors and acetylcholinesterase in the treatment of postoperative ileus after cholecystectomy. Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Cholecystectomy; Clinical Trials as Topic; Double-Blind Method; Drug Therap	1987
Treatment of paralytic ileus with adrenergic neuronal blocking drugs. Surgery, 1971, Volume: 69, Issue:4 Topics: Clinical Trials as Topic; Guanidines; Humans; Intestinal Obstruction; Neostigmine; Placebos; Postope	1971

Other Studies

38 other studies available for neostigmine and Intestinal Obstruction

Article	Year
Acute colonic pseudo-obstruction in pregnancy. ANZ journal of surgery, 2015, Volume: 85, Issue:10 Topics: Abdominal Pain; Acute Disease; Adult; Anti-Bacterial Agents; Cesarean Section; Colonic Pseudo-Obstru	2015
Successful use of neostigmine in a patient with refractory distal intestinal obstruction syndrome. Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35, Issue:5 Topics: Adult; Cholinesterase Inhibitors; Cystic Fibrosis; Female; Humans; Injections, Intravenous; Intestin	2002
Treatment of paralytic ileus with cholinesterase inhibitors in intravenous drip. Acta chirurgica Scandinavica, 1958, Mar-08, Volume: 114, Issue:3 Topics: Cholinesterase Inhibitors; Humans; Infusions, Intravenous; Intestinal Obstruction; Intestinal Pseudo	1958
[Prevention and therapy of postoperative intestinal paralysis]. Vestnik khirurgii imeni I. I. Grekova, 1963, Volume: 90 Topics: Bromides; Humans; Intestinal Obstruction; Neostigmine; Pituitary Hormones; Pituitary Hormones, Poste	1963
[INFECTIOUS INTESTINAL DISEASES IN CHILDHOOD (WITH SPECIAL REFERENCE TO THEIR THERAPY)]. Medizinische Klinik, 1963, Sep-13, Volume: 58 Topics: Adolescent; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Dyse	1963
RESPIRATORY AND CARDIAC ARREST AFTER INTRAVENOUS ADMINISTRATION OF KANAMYCIN WITH REVERSAL OF TOXIC EFFECTS BY NEOSTIGMINE. Annals of internal medicine, 1963, Volume: 59 Topics: Abscess; Administration, Intravenous; Adolescent; Appendix; Drug Hypersensitivity; Escherichia coli	1963
[OBSERVATIONS ON POSTOPERATIVE GASTROINTESTINAL ATONY AFTER STOMACH SURGERY]. Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1963, Nov-05, Volume: 304 Topics: Autonomic Nervous System Diseases; Humans; Hypokalemia; Intestinal Obstruction; Neostigmine; Postgas	1963
[RADIOLOGICAL STUDIES ON THE RESTORATION OF POSTOPERATIVE PARALYTIC ILEUS AND THE EFFECT OF VARIOUS DRUGS AND MANAGEMENT]. Rinsho geka. Journal of clinical surgery, 1964, Volume: 19 Topics: Atropine; Humans; Hypertonic Solutions; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Neost	1964
[A CONTRIBUTION TO THE TREATMENT OF INTESTINAL PARALYSIS IN CHILDHOOD]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1964, Volume: 35 Topics: Acidosis; Humans; Hypoxia; Infant; Intestinal Obstruction; Intussusception; Neostigmine; Postoperati	1964
PARALYTIC ILEUS DUE TO METHOCARBAMOL. Clinical medicine (Northfield, Ill.), 1964, Volume: 71 Topics: Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Methocarbamol; Muscle Cramp; Neostigm	1964
An analysis of the autonomic control of gastrointestinal motility in the cat. Gut, 1967, Volume: 8, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Cats; Digestive System; Gastrointestinal Motility; Guan	1967
Intestinal motility in low small bowel obstruction. Animal experiments with endoradiosondes. Acta chirurgica Scandinavica, 1967, Volume: 133, Issue:5 Topics: Animals; Cholecystokinin; Dogs; Gastrointestinal Motility; Ileum; Intestinal Obstruction; Neostigmin	1967
Mechanisms of motility changes during acute intestinal obstruction in the dog. The American journal of physiology, 1984, Volume: 247, Issue:1 Pt 1 Topics: Animals; Atropine; Dogs; Electrodes, Implanted; Electromyography; Female; Gastrointestinal Motility;	1984
[Treatment of functional ileus: adrenergic blockade and stimulation (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1982, Feb-12, Volume: 107, Issue:6 Topics: Adolescent; Adult; Aged; Ceruletide; Child; Child, Preschool; Chlorpromazine; Dihydroergotamine; Fem	1982
Small intestinal blood flow after 48 hours ileus, prostigmin and manual decompression. Zeitschrift fur experimentelle Chirurgie, 1980, Volume: 13, Issue:5 Topics: Animals; Gastrointestinal Motility; Intestinal Obstruction; Intestine, Small; Microspheres; Neostigm	1980
Adrenergic and cholinergic contributions to decreased gastric emptying, small intestinal transit, and colonic transit in the postoperative ileus rat. The Journal of surgical research, 1980, Volume: 29, Issue:2 Topics: Animals; Bethanechol Compounds; Colon; Disease Models, Animal; Gastric Emptying; Gastrointestinal Mo	1980
Does neostigmine have a deleterious effect on the resistance of colonic anastomoses? European journal of anaesthesiology, 1998, Volume: 15, Issue:1 Topics: Anastomosis, Surgical; Animals; Body Weight; Cecum; Cholinergic Agents; Colon; Female; Gastrointesti	1998
Successful decompression of colonic pseudo-obstruction with neostigmine. The American journal of gastroenterology, 1999, Volume: 94, Issue:11 Topics: Cholinesterase Inhibitors; Colonic Diseases; Colonic Pseudo-Obstruction; Diabetes Mellitus, Type 2;	1999
[Neostigmine for the treatment of acute pseudo-obstruction of the colon (Ogilvie syndrome)]. Nederlands tijdschrift voor geneeskunde, 2001, May-26, Volume: 145, Issue:21 Topics: Acute Disease; Colonic Pseudo-Obstruction; Contraindications; Diagnosis, Differential; Humans; Intes	2001
Treatment of anticholinergic-induced ileus with neostigmine. Annals of emergency medicine, 2001, Volume: 38, Issue:6 Topics: Adult; Benztropine; Cholinergic Antagonists; Emergency Service, Hospital; Gastrointestinal Motility;	2001
[Treatment of paralytic ileus using alpha and beta-lytics]. Bollettino della Societa italiana di biologia sperimentale, 1976, Jul-30, Volume: 52, Issue:14 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Humans; Intestinal Obstruction; Int	1976
[Postoperative ileus. Measurement of the changes in intragastric pressure immediately after abdominal operations (practical deductions)]. Journal de chirurgie, 1975, Volume: 109, Issue:4 Topics: Abdomen; Adrenergic beta-Antagonists; Gastrointestinal Motility; Humans; Intestinal Obstruction; Int	1975
[Effect of dihydergot on the postoperative intestinal atonia. Experimental studies]. Die Medizinische Welt, 1978, Dec-15, Volume: 29, Issue:50 Topics: Animals; Dihydroergotamine; Female; Intestinal Obstruction; Male; Neostigmine; Postoperative Complic	1978
Gastrointestinal myoelectrical activity in idiopathic intestinal pseudo-obstruction. The New England journal of medicine, 1977, Aug-04, Volume: 297, Issue:5 Topics: Adult; Anal Canal; Chronic Disease; Colon; Diagnosis, Differential; Duodenum; Electromyography; Esop	1977
Effects of some drugs on electrical activity of the gut in the postoperative period. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1976, Volume: 8, Issue:1 Topics: Cholecystectomy; Cholecystokinin; Gastrointestinal Motility; Humans; Intestinal Obstruction; Jejunum	1976
Atrial fibrillation associated with neostigmine administration in three cows. Journal of the American Veterinary Medical Association, 1990, Jan-15, Volume: 196, Issue:2 Topics: Animals; Atrial Fibrillation; Cattle; Cattle Diseases; Electrocardiography; Female; Intestinal Obstr	1990
[Computer-assisted drug therapy of incomplete ileus]. Helvetica chirurgica acta, 1989, Volume: 56, Issue:1-2 Topics: Auscultation; Computers; Drug Therapy, Computer-Assisted; Gastrointestinal Motility; Humans; Intesti	1989
[Treatment of postoperatory ileus with several drugs]. Revista espanola de las enfermedades del aparato digestivo, 1989, Volume: 76, Issue:2 Topics: Animals; Drug Combinations; Intestinal Obstruction; Mepivacaine; Neostigmine; Phentolamine; Postoper	1989
[Clinical and experimental studies on the mechanism of neuromucular blockade by chloroquine diorotate]. Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:6 Topics: Action Potentials; Adolescent; Adult; Aged; Animals; Anura; Calcium Chloride; Chloroquine; Dogs; Ele	1971
Ultrasound for detecting peristalsis. British medical journal, 1972, Sep-16, Volume: 3, Issue:5828 Topics: Gastrointestinal Motility; Humans; Intestinal Obstruction; Neostigmine; Surgical Procedures, Operati	1972
[Therapy of paralytic ileus]. Minerva medica, 1973, Aug-18, Volume: 64, Issue:58 Topics: Dehydration; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Neostigmine; Sodium Chlo	1973
Effects of altered propulsion on rat small intestinal flora. Gastroenterology, 1970, Volume: 59, Issue:5 Topics: Animals; Bacteria; Bacteroides; Chlorisondamine; Clostridium; Enterobacteriaceae; Escherichia coli;	1970
Management of resistant ileus by the Neely-Catchpole regimen. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Mar-11, Volume: 46, Issue:11 Topics: Aged; Chronic Disease; Depression, Chemical; Drug Resistance; Female; Guanethidine; Humans; Injectio	1972
Ileus and pseudo-obstruction. British medical journal, 1971, Jun-26, Volume: 2, Issue:5764 Topics: Abdomen; Aged; Female; Gases; Gastrointestinal Motility; Guanethidine; Humans; Intestinal Obstructio	1971
Chronic idiopathic intestinal pseudo-obstruction. The American journal of medicine, 1970, Volume: 49, Issue:2 Topics: Abdomen, Acute; Acidosis; Adolescent; Adult; Anemia; Celiac Disease; Chronic Disease; Deficiency Dis	1970
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion. Gastroenterology, 1970, Volume: 59, Issue:5 Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ile	1970
Ileus: the restoration of alimentary-tract motility by pharmacological means. The British journal of surgery, 1971, Volume: 58, Issue:1 Topics: Aged; Bethanechol Compounds; Female; Gastrointestinal Motility; Guanethidine; Humans; Intestinal Obs	1971
[Contribution to the use of Neoeserine in intestinal radiography]. Zeitschrift fur arztliche Fortbildung, 1967, Dec-01, Volume: 61, Issue:23 Topics: Adult; Child; Contrast Media; Humans; Intestinal Diseases; Intestinal Obstruction; Neostigmine; Phys	1967