Page last updated: 2024-10-31

neostigmine and Insulin Sensitivity

neostigmine has been researched along with Insulin Sensitivity in 2 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Research Excerpts

ExcerptRelevanceReference
" Blockade of the parasympathetic feeding signal to the liver, either through surgical denervation or atropine-mediated antagonism of hepatic muscarinic receptors, eliminates the HISS response, resulting in HISS-dependent insulin resistance (HDIR) and decreasing the response to insulin by approximately 55% in the fed state."3.76Acetylcholinesterase antagonist potentiated insulin action in fed but not fasted state. ( Lautt, WW; Legare, DJ; Schafer, J, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schafer, J1
Legare, DJ1
Lautt, WW1
Grassiolli, S1
Gravena, C1
de Freitas Mathias, PC1

Other Studies

2 other studies available for neostigmine and Insulin Sensitivity

ArticleYear
Acetylcholinesterase antagonist potentiated insulin action in fed but not fasted state.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:2

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug

2010
Muscarinic M2 receptor is active on pancreatic islets from hypothalamic obese rat.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Acetylcholine; Animals; Animals, Newborn; Diamines; Glucose Tolerance Test; Hypothalamus; In Vitro T

2007