neostigmine has been researched along with Inflammation in 14 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two hours later (T1), both hindpaws were tested for inflammation (paw circumference) and for hyperalgesia (paw withdrawal threshold) and subsequently 20 microg of neostigmine was injected in the right hind paw." | 3.71 | Lack of peripheral analgesia mediated by intraplantar administration of neostigmine in carrageenan-injected rats. ( Benhamou, D; Bouaziz, H; Fletcher, D; Gentili, ME; Girard, F; Laxenaire, MC; Mazoit, JX, 2001) |
| "On the other hand, in the presence of neuropathic pain, atropine (300 μg) did not alter the nociceptive threshold induced by constriction of the sciatic nerve." | 1.37 | Peripheral control of inflammatory but not neuropathic pain by endogenous cholinergic system. ( Alves, DP; Duarte, ID; Motta, PG; Perez, AC, 2011) |
| "IT neostigmine was found to suppress both leukocyte migration and MPO degranulation in a dose dependent manner." | 1.33 | Intrathecal neostigmine reduces the zymosan-induced inflammatory response in a mouse air pouch model via adrenomedullary activity: involvement of spinal muscarinic type 2 receptors. ( Beitz, AJ; Han, HJ; Kang, SY; Kim, CY; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Yang, IS; Yoon, SY, 2005) |
| "There was an increased incidence of delayed hypersensitivity and circulating thymus antibodies in the immunized guinea-pigs and an increased incidence of thymitis in the immunized guinea-pigs and rats." | 1.25 | An investigation of experimental myasthenia gravis. ( Brennan, JL; Jones, SF; McLeod, JG, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, F | 1 |
| Saand, A | 1 |
| Xing, C | 1 |
| Lee, JW | 1 |
| Hsu, L | 1 |
| Palmer, OP | 1 |
| Jackson, V | 1 |
| Tang, L | 1 |
| Ning, M | 1 |
| Du, R | 1 |
| Kochanek, PM | 1 |
| Lo, EH | 1 |
| Chou, SH | 1 |
| Herman, AP | 2 |
| Skipor, J | 2 |
| Krawczyńska, A | 2 |
| Bochenek, J | 1 |
| Wojtulewicz, K | 1 |
| Antushevich, H | 2 |
| Herman, A | 1 |
| Paczesna, K | 1 |
| Romanowicz, K | 1 |
| Tomaszewska-Zaremba, D | 2 |
| Kowalewska, M | 1 |
| Szczepkowska, A | 1 |
| Oleszkiewicz, M | 1 |
| Wójcik, M | 1 |
| Antunes, GL | 1 |
| Silveira, JS | 1 |
| Kaiber, DB | 1 |
| Luft, C | 1 |
| da Costa, MS | 1 |
| Marques, EP | 1 |
| Ferreira, FS | 1 |
| Breda, RV | 1 |
| Wyse, ATS | 1 |
| Stein, RT | 1 |
| Pitrez, PM | 1 |
| da Cunha, AA | 1 |
| Moriya, M | 1 |
| Oda, S | 1 |
| Nakane, M | 1 |
| Kawamae, K | 1 |
| Li, CH | 1 |
| Zhang, X | 1 |
| Ge, XL | 1 |
| Huang, X | 1 |
| Zhang, AQ | 1 |
| Gu, WQ | 1 |
| Zeinali, F | 1 |
| Stulberg, JJ | 1 |
| Delaney, CP | 1 |
| Motta, PG | 1 |
| Perez, AC | 1 |
| Alves, DP | 1 |
| Duarte, ID | 1 |
| Masaki, E | 1 |
| Saito, H | 1 |
| Shoji, K | 1 |
| Matsushima, M | 1 |
| Yoon, SY | 1 |
| Kwon, YB | 1 |
| Kim, HW | 1 |
| Roh, DH | 1 |
| Kang, SY | 1 |
| Kim, CY | 1 |
| Han, HJ | 1 |
| Kim, KW | 1 |
| Yang, IS | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
| Baek, YH | 1 |
| Choi, DY | 1 |
| Yang, HI | 1 |
| Park, DS | 1 |
| Buerkle, H | 1 |
| Bantel, C | 1 |
| Wuesten, R | 1 |
| Mae, M | 1 |
| Van Aken, H | 1 |
| Bouaziz, H | 1 |
| Gentili, ME | 1 |
| Girard, F | 1 |
| Mazoit, JX | 1 |
| Benhamou, D | 1 |
| Laxenaire, MC | 1 |
| Fletcher, D | 1 |
| Jones, SF | 1 |
| Brennan, JL | 1 |
| McLeod, JG | 1 |
1 review available for neostigmine and Inflammation
| Article | Year |
|---|---|
Pharmacological management of postoperative ileus.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; | 2009 |
1 trial available for neostigmine and Inflammation
| Article | Year |
|---|---|
Postoperative analgesic effect of epidural neostigmine and plasma cortisol and IL-6 responses.
Topics: Adult; Analgesia, Epidural; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Double-Blin | 2004 |
12 other studies available for neostigmine and Inflammation
| Article | Year |
|---|---|
CSF lipocalin-2 increases early in subarachnoid hemorrhage are associated with neuroinflammation and unfavorable outcome.
Topics: Aged; Cerebrospinal Fluid; Female; Humans; Inflammation; Lipocalin-2; Male; Middle Aged; Neostigmine | 2021 |
Peripheral Inhibitor of AChE, Neostigmine, Prevents the Inflammatory Dependent Suppression of GnRH/LH Secretion during the Follicular Phase of the Estrous Cycle.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Estrous Cycle; Female; Follicular Phase; G | 2017 |
Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation.
Topics: Animals; Cholinesterase Inhibitors; Choroid Plexus; Cytokines; Enzyme-Linked Immunosorbent Assay; Fe | 2018 |
Cholinergic anti-inflammatory pathway confers airway protection against oxidative damage and attenuates inflammation in an allergic asthma model.
Topics: Animals; Asthma; Cholinesterase Inhibitors; Disease Models, Animal; Female; Inflammation; Mice; Mice | 2020 |
[Severe asthmatic crisis during general anesthesia in a patient with IgG4 related disease].
Topics: Anesthesia, General; Asthma; Bronchial Hyperreactivity; Humans; Immunoglobulin G; Inflammation; Intr | 2014 |
Effects of combined anisodamine and neostigmine treatment on the inflammatory response and liver regeneration of obstructive jaundice rats after hepatectomy.
Topics: Animals; Drug Combinations; Hepatectomy; Humans; Inflammation; Interleukin-6; Jaundice, Obstructive; | 2014 |
Peripheral control of inflammatory but not neuropathic pain by endogenous cholinergic system.
Topics: Animals; Atropine; Carrageenan; Cholinergic Agents; Cholinesterase Inhibitors; Dinoprostone; Disease | 2011 |
Intrathecal neostigmine reduces the zymosan-induced inflammatory response in a mouse air pouch model via adrenomedullary activity: involvement of spinal muscarinic type 2 receptors.
Topics: Adrenal Cortex Hormones; Adrenal Medulla; Adrenalectomy; Air; Animals; Anti-Inflammatory Agents; Cat | 2005 |
Analgesic effect of electroacupuncture on inflammatory pain in the rat model of collagen-induced arthritis: mediation by cholinergic and serotonergic receptors.
Topics: Acupuncture Points; Analysis of Variance; Animals; Arthritis, Experimental; Cholinesterase Inhibitor | 2005 |
Continuing inflammation does enhance spinally mediated antinociception by neostigmine in the rat model.
Topics: Acetylcholine; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Inflammation; In | 1999 |
Lack of peripheral analgesia mediated by intraplantar administration of neostigmine in carrageenan-injected rats.
Topics: Analgesics; Animals; Carrageenan; Cholinesterase Inhibitors; Foot; Hyperalgesia; Inflammation; Injec | 2001 |
An investigation of experimental myasthenia gravis.
Topics: Action Potentials; Animals; Antibodies; Antigens; Cattle; Disease Models, Animal; Electromyography; | 1971 |