neostigmine has been researched along with Hypoxia in 15 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study is to comparison of neuromuscular blockade and reversal using cisatricurium and neostigmine with rocuronium and sugamadex on the quality of recovery from general anaesthesia for percutaneous closure of left atria appendage." | 9.51 | A comparison of neuromuscular blockade and reversal using cisatricurium and neostigmine with rocuronium and sugamadex on the quality of recovery from general anaesthesia for percutaneous closure of left atria appendage. ( Li, Q; Wu, D; Wu, J; Xie, H; Xu, M; Yao, H, 2022) |
| " The aim of the study is to comparison of neuromuscular blockade and reversal using cisatricurium and neostigmine with rocuronium and sugamadex on the quality of recovery from general anaesthesia for percutaneous closure of left atria appendage." | 5.51 | A comparison of neuromuscular blockade and reversal using cisatricurium and neostigmine with rocuronium and sugamadex on the quality of recovery from general anaesthesia for percutaneous closure of left atria appendage. ( Li, Q; Wu, D; Wu, J; Xie, H; Xu, M; Yao, H, 2022) |
| "In this single-center, experimental, randomized, controlled trial, ventilatory responses to 5-min hypoxia (oxygen saturation, 80 ± 2%) and ventilation at hyperoxic isohypercapnia (end-tidal carbon dioxide concentration, 55 mmHg) were obtained at baseline, during rocuronium-induced partial neuromuscular block (train-of-four ratio of 0." | 5.30 | Reversal of Partial Neuromuscular Block and the Ventilatory Response to Hypoxia: A Randomized Controlled Trial in Healthy Volunteers. ( Aarts, LPHJ; Boon, M; Broens, SJL; Dahan, A; Martini, CH; Niesters, M; van Velzen, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Yao, H | 1 |
| Wu, J | 1 |
| Xu, M | 1 |
| Xie, H | 1 |
| Wu, D | 1 |
| Broens, SJL | 1 |
| Boon, M | 1 |
| Martini, CH | 1 |
| Niesters, M | 1 |
| van Velzen, M | 1 |
| Aarts, LPHJ | 1 |
| Dahan, A | 1 |
| Grosse-Sundrup, M | 1 |
| Henneman, JP | 1 |
| Sandberg, WS | 1 |
| Bateman, BT | 1 |
| Uribe, JV | 1 |
| Nguyen, NT | 1 |
| Ehrenfeld, JM | 1 |
| Martinez, EA | 1 |
| Kurth, T | 1 |
| Eikermann, M | 1 |
| ANDERS, M | 1 |
| NIESCHKE, W | 1 |
| DAHM, H | 1 |
| TAUGNER, R | 1 |
| VARAGIC, VM | 1 |
| BELESLIN, DB | 1 |
| YAMASHITA, K | 1 |
| MORI, S | 1 |
| ABE, M | 1 |
| OTA, M | 1 |
| NISHIGUCHI, M | 1 |
| MIYAZATO, Y | 1 |
| EICHBAUM, FW | 1 |
| PEREIRA, CB | 1 |
| ROYER, R | 1 |
| LAMARCHE, M | 1 |
| DALICHAMPS, P | 1 |
| HELBIG, D | 1 |
| Saiyed, M | 1 |
| Riker, WK | 1 |
| Baurain, MJ | 1 |
| Hoton, F | 1 |
| Dernovoi, BS | 1 |
| d'Hollander, AA | 1 |
| Bucher, K | 1 |
| Benz-Lippold, M | 1 |
| Bättig, P | 1 |
| List, WF | 1 |
| Harrison, GA | 1 |
| Bailey, RJ | 1 |
| Thomson, PG | 1 |
| Coleman, AJ | 1 |
| Sliom, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Intraoperative Neuromuscular Blockade on Postoperative Atelectasis in Patients Undergoing Thoracic Surgery With One Lung Ventilation: Moderate vs. Deep Block[NCT03503565] | 118 participants (Actual) | Observational | 2018-10-11 | Completed | |||
| Visualization of Regional Lung Ventilation During Neostigmine or Sugammadex Enhanced Recovery From Moderate Residual Neuromuscular Blockade in the Anaesthetized Rat Using Functional Respiratory Imaging[NCT02284412] | Phase 4 | 13 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| Effects of Postoperative Residual Paralysis on Costs of Hospital Care, Length of Hospitalization and Intensive Care Unit Admission Rate[NCT01718860] | 3,000 participants (Anticipated) | Observational | 2011-04-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Atelectasis on Chest CT The lung area was delineated manually. To calculate atelectasis, a region of interest was laid out that encircled the dense part of the lung, excluding large vessels. For further analysis, the lung was divided into four categories: areas with densities ranging from -1000 to -900 Hounsfield units (HU) were classified as over-aerated, from -900 to -500 HU as normally aerated, from -500 to -100 HU as poorly aerated, and from -100 to +100 HU as non-aerated (atelectasis). The proportion of non-aerated lung tissue (-100 to +100 HU) was calculated by dividing the area of the region of interest with the whole lungs. (NCT03503565)
Timeframe: 1 day after the end of surgery
| Intervention | percentage of atelectasis volume (Median) |
|---|---|
| Moderate Block Group | 1.32 |
| Deep Block Group | 1.41 |
1 review available for neostigmine and Hypoxia
| Article | Year |
|---|---|
[Cardiac arrhythmias during anesthesia: their origin and pharmacological control].
Topics: Anesthetics; Arrhythmias, Cardiac; Catecholamines; Digitalis Glycosides; Electroshock; Heart Disease | 1966 |
3 trials available for neostigmine and Hypoxia
| Article | Year |
|---|---|
A comparison of neuromuscular blockade and reversal using cisatricurium and neostigmine with rocuronium and sugamadex on the quality of recovery from general anaesthesia for percutaneous closure of left atria appendage.
Topics: Anesthesia, General; Atrial Appendage; gamma-Cyclodextrins; Humans; Hypoxia; Neostigmine; Neuromuscu | 2022 |
Reversal of Partial Neuromuscular Block and the Ventilatory Response to Hypoxia: A Randomized Controlled Trial in Healthy Volunteers.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Cholinesterase Inhibitors; Double-Blind Method; Elect | 2019 |
Influence and relative sensitivities of 50-Hz and 100-Hz tetanic stimuli on subsequent tetanic fade ratios in patients receiving vecuronium.
Topics: Adolescent; Adult; Atropine; Cholinesterase Inhibitors; Electric Stimulation; Evaluation Studies as | 1996 |
11 other studies available for neostigmine and Hypoxia
| Article | Year |
|---|---|
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema | 2012 |
[Comparative pharmacological studies on tired, anoxemic and normal skeletal muscle].
Topics: Hypoxia; Muscle, Skeletal; Muscles; Neostigmine; Physostigmine; Potassium; Strophanthins; Xanthines | 1953 |
Comparison of adrenergic activation by anticholinesterases and by hypoxia.
Topics: Adrenergic Agents; Atropine; Blood Pressure; Bretylium Compounds; Cholinesterase Inhibitors; Gallami | 1962 |
[STUDIES ON EARLY OPERATIVE DEATHS].
Topics: Anesthesia; Anesthesia, General; Anesthesiology; Hypoxia; Japan; Mortality; Neostigmine; Surgical Pr | 1963 |
EFFECT OF CRANIAL TRAUMA ON THE ELECTROCARDIOGRAM EXPERIMENTS IN GUINEA-PIGS.
Topics: Arrhythmias, Cardiac; Atropine; Brain Injuries; Craniocerebral Trauma; Electrocardiography; Ergotami | 1964 |
[STUDY OF THE ANTICHOLINESTERASE ACTIVITY OF THE NICOTINIC ESTER OF DIETHYLAMINOETHANOL].
Topics: Amino Alcohols; Cholinesterase Inhibitors; Cholinesterases; Enzyme Inhibitors; Ethanolamines; Guinea | 1963 |
[A CONTRIBUTION TO THE TREATMENT OF INTESTINAL PARALYSIS IN CHILDHOOD].
Topics: Acidosis; Humans; Hypoxia; Infant; Intestinal Obstruction; Intussusception; Neostigmine; Postoperati | 1964 |
Cholinergic and anticholinergic drug effects on survival during hypoxia: significant gender differences.
Topics: Animals; Atropine; Body Temperature; Female; Hypoxia; Male; Mice; Neostigmine; Parasympatholytics; P | 1993 |
Peak-potentialities of inspiratory musculature as disclosed by tracheal occlusion.
Topics: Animals; Atropine; Central Nervous System Stimulants; Diaphragm; Female; Hypercapnia; Hypoxia; Male; | 1973 |
A heart transplantation. 4. Anaesthesia and cardio-pulmonary bypass.
Topics: Acidosis; Anesthesia, General; Anuria; Atropine; Australia; Blood Pressure; Coronary Vessels; Extrac | 1969 |
Polycythaemic hypoxaemia and general anaesthesia. A case report.
Topics: Atropine; Humans; Hypoxia; Male; Middle Aged; Neostigmine; Polycythemia; Thiopental; Tubocurarine | 1966 |