Page last updated: 2024-10-31

neostigmine and Heart Arrest

neostigmine has been researched along with Heart Arrest in 23 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.

Research Excerpts

ExcerptRelevanceReference
" We report the case of a critically ill patient with ACPO who experienced bradycardia and a brief episode of asystole when receiving concomitant dexmedetomidine and neostigmine infusions but who later remained hemodynamically stable when receiving propofol and neostigmine infusions."8.12Asystole Following Concomitant Intravenous Administration of Neostigmine and Dexmedetomidine in a Patient With Acute Colonic Pseudo-Obstruction. ( Bell, CM; Parli, SE; Procter, LD, 2022)
"To describe a heart transplant recipient who developed asystole after administration of neostigmine which suggests that surgical dennervation of the heart may not permanently prevent significant responses to anticholinesterases."7.71Asystole after intravenous neostigmine in a heart transplant recipient. ( Bjerke, RJ; Mangione, MP, 2001)
"Sugammadex and neostigmine given to reverse residual neuromuscular blockade can cause side effects including bradycardia, anaphylaxis, bronchospasm, and even cardiac arrest."4.12Sugammadex Versus Neostigmine for Reversal of Residual Neuromuscular Blocks After Surgery: A Retrospective Cohort Analysis of Postoperative Side Effects. ( Chahar, P; Chhabada, S; Khanna, S; Li, K; Maheshwari, K; Ruetzler, K; Schmidt, MT; Sessler, DI; Turan, A; Yang, D, 2022)
" We report the case of a critically ill patient with ACPO who experienced bradycardia and a brief episode of asystole when receiving concomitant dexmedetomidine and neostigmine infusions but who later remained hemodynamically stable when receiving propofol and neostigmine infusions."4.12Asystole Following Concomitant Intravenous Administration of Neostigmine and Dexmedetomidine in a Patient With Acute Colonic Pseudo-Obstruction. ( Bell, CM; Parli, SE; Procter, LD, 2022)
"To describe a heart transplant recipient who developed asystole after administration of neostigmine which suggests that surgical dennervation of the heart may not permanently prevent significant responses to anticholinesterases."3.71Asystole after intravenous neostigmine in a heart transplant recipient. ( Bjerke, RJ; Mangione, MP, 2001)
"However, cardiac arrest developed immediately after administration."1.38Immediate cardiac arrest after neostigmine administration. ( Aycan, IO; Celik, F; Karaman, H; Tokgöz, O; Tüfek, A; Yildirim, B, 2012)
"Here, we report a case of cardiac arrest complicating neostigmine use in a 16-year-old woman with cerebral palsy who was being treated in the intensive care unit after orthopaedic surgery."1.37Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient. ( Maher, L; Young, PJ, 2011)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199013 (56.52)18.7374
1990's1 (4.35)18.2507
2000's4 (17.39)29.6817
2010's3 (13.04)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Ruetzler, K1
Li, K1
Chhabada, S1
Maheshwari, K1
Chahar, P1
Khanna, S1
Schmidt, MT1
Yang, D1
Turan, A1
Sessler, DI1
Bell, CM1
Procter, LD1
Parli, SE1
Cachemaille, M1
Olofsson, M1
Livio, F1
Pascale, P1
Zingg, T1
Boegli, Y1
Maher, L1
Young, PJ1
Tüfek, A1
Yildirim, B1
Tokgöz, O1
Karaman, H1
Celik, F1
Aycan, IO1
LAWSON, JI1
MERRITT, DM1
SEALY, WC3
YOUNG, WG3
HARRIS, FS1
BROWN, IW2
LESAGE, A1
CALLAWAY, HA1
HARRIS, JS2
MERRITT, DH2
MARITANO, M1
QUERCI, M1
HUBKA, M1
SUJANSKY, E1
SILVAY, J1
FEDELESOVA, M1
ZIEGELHOEFFER, A1
REAM, CR1
POTRUSIL, B1
UHLIR, J1
HANZL, J1
Sawasdiwipachai, P1
Laussen, PC1
McGowan, FX1
Smoot, L1
Casta, A1
Backman, SB1
Beebe, DS1
Shumway, SJ1
Maddock, R1
Bjerke, RJ1
Mangione, MP1
Laothong, C1
Sitprija, V1
Geevarghese, KP1
Shields, CB1
Gray, LA1
Chiche, P1
Lellouch, A1
Denizeau, JP1
Stovner, J1
Lund, I1
Kanarek, KS1
Thomson, PD1
Levin, SE1
Pleuvry, BJ1
Hunter, AR1

Reviews

1 review available for neostigmine and Heart Arrest

ArticleYear
The muscle relaxants and their antagonists.
    British journal of anaesthesia, 1970, Volume: 42, Issue:3

    Topics: Acid-Base Equilibrium; Androstanes; Animals; Anura; Blood Pressure; Carbon Dioxide; Cats; Cholineste

1970

Other Studies

22 other studies available for neostigmine and Heart Arrest

ArticleYear
Sugammadex Versus Neostigmine for Reversal of Residual Neuromuscular Blocks After Surgery: A Retrospective Cohort Analysis of Postoperative Side Effects.
    Anesthesia and analgesia, 2022, 05-01, Volume: 134, Issue:5

    Topics: Anaphylaxis; Bradycardia; Bronchial Spasm; Child; Cohort Studies; Delayed Emergence from Anesthesia;

2022
Asystole Following Concomitant Intravenous Administration of Neostigmine and Dexmedetomidine in a Patient With Acute Colonic Pseudo-Obstruction.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:4

    Topics: Acute Disease; Bradycardia; Colonic Pseudo-Obstruction; Dexmedetomidine; Heart Arrest; Humans; Infus

2022
Recurrent Asystole After Neostigmine in a Heart Transplant Recipient With End-Stage Renal Disease.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:2

    Topics: Aged; Cholinesterase Inhibitors; Heart Arrest; Heart Transplantation; Humans; Kidney Failure, Chroni

2017
Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2011, Volume: 13, Issue:3

    Topics: Adolescent; Bradycardia; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Critical Illness; Fe

2011
Immediate cardiac arrest after neostigmine administration.
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:6

    Topics: Electrocardiography; Glaucoma; Heart Arrest; Humans; Infant; Male; Neostigmine; Parasympathomimetics

2012
Cardiac arrest following the administration of neostigmine.
    British journal of anaesthesia, 1956, Volume: 28, Issue:7

    Topics: Heart Arrest; Humans; Neostigmine

1956
Potassium, magnesium, and neostigmine for controlled cardioplegia; evaluation with the isolated perfused cat heart.
    A.M.A. archives of surgery, 1958, Volume: 76, Issue:3

    Topics: Animals; Cats; Felis; Heart; Heart Arrest; Heart Arrest, Induced; Humans; Magnesium; Neostigmine; Po

1958
Potassium, magnesium, and neostigmine for controlled cardioplegia; studies on the deg using extracorporeal circulation and hypothermia.
    A.M.A. archives of surgery, 1958, Volume: 77, Issue:1

    Topics: Citrates; Extracorporeal Circulation; Heart Arrest; Heart Arrest, Induced; Humans; Hypothermia; Magn

1958
Potassium, magnesium, and neostigmine for controlled cardioplegia: a report of its use in 34 patients.
    The Journal of thoracic surgery, 1959, Volume: 37, Issue:5

    Topics: Cardiac Surgical Procedures; Heart Arrest; Heart Arrest, Induced; Humans; Magnesium; Neostigmine; Po

1959
[ON CARDIAC ARREST INDUCED IN MAN DURING ANESTHESIA. POTENTIATION OF THE OCULO-CARDIAC REFLEX WITH ANTICHOLINESTERASE DRUGS].
    Minerva anestesiologica, 1963, Volume: 29

    Topics: Anesthesia; Anesthesia, General; Cholinesterase Inhibitors; Electrocardiography; Eye; Galantamine; H

1963
[CURRENT STATUS OF THE PROBLEM OF ARTIFICIAL ASYSTOLES].
    Bratislavske lekarske listy, 1963, Volume: 2

    Topics: Cardiac Surgical Procedures; Heart; Heart Arrest; Heart, Artificial; Humans; Hypothermia; Hypothermi

1963
RESPIRATORY AND CARDIAC ARREST AFTER INTRAVENOUS ADMINISTRATION OF KANAMYCIN WITH REVERSAL OF TOXIC EFFECTS BY NEOSTIGMINE.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Abscess; Administration, Intravenous; Adolescent; Appendix; Drug Hypersensitivity; Escherichia coli

1963
[Cardioplegia induced by a combination of syntostigmin with acetylcholine].
    Scripta medica, 1962, Volume: 35

    Topics: Acetylcholine; Heart Arrest; Heart Arrest, Induced; Neostigmine

1962
Cardiac arrest after neuromuscular blockade reversal in a heart transplant infant.
    Anesthesiology, 2007, Volume: 107, Issue:4

    Topics: Biopsy; Cardiac Catheterization; Cardiovascular Abnormalities; Cholinesterase Inhibitors; Graft Reje

2007
Anticholinesterase drugs and the transplanted heart.
    Anesthesiology, 2008, Volume: 108, Issue:5

    Topics: Cholinesterase Inhibitors; Graft Rejection; Heart Arrest; Heart Transplantation; Humans; Infant; Mal

2008
Sinus arrest after intravenous neostigmine in two heart transplant recipients.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:4

    Topics: Glycopyrrolate; Heart Arrest; Heart Transplantation; Humans; Injections, Intravenous; Male; Middle A

1994
Asystole after intravenous neostigmine in a heart transplant recipient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:3

    Topics: Aged; Cholinesterase Inhibitors; Denervation; Heart Arrest; Heart Transplantation; Humans; Lung; Mal

2001
Decreased parasympathetic activities in Malayan krait (Bungarus candidus) envenoming.
    Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:9

    Topics: Adult; Animals; Autonomic Nervous System Diseases; Brain Damage, Chronic; Bungarus; Child; Female; H

2001
Anesthetic management for direct approach to carotid-cavernous fistula: case report.
    International anesthesiology clinics, 1977,Fall, Volume: 15, Issue:3

    Topics: Adult; Anesthesia; Arteriovenous Fistula; Atropine; Carotid Artery Diseases; Cavernous Sinus; Dexame

1977
Autonomic influences and cardiac conduction in patients with sinus node disease.
    Cardiology, 1976, Volume: 61 suppl 1

    Topics: Adult; Aged; Ajmaline; Arrhythmia, Sinus; Atropine; Blood Pressure; Bradycardia; Bundle of His; Digi

1976
The management of imipramine (Tofranil) intoxication in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-19, Volume: 47, Issue:19

    Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lava

1973
Antagonists to neuromuscular blocking agents. An experimental study.
    British journal of anaesthesia, 1968, Volume: 40, Issue:10

    Topics: Acetylcholine; Ambenonium Chloride; Animals; Anura; Curare; Diaphragm; Drug Synergism; Edrophonium;

1968