neostigmine has been researched along with Fasciculation in 5 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neostigmine-induced muscle fasciculations, quantitated as fasciculatory muscle action potentials, served as an indirect in vivo indicator of motor nerve ending (MNE) excitability." | 7.67 | Pharmacologic excitability of rat motor nerve endings: the effect of adrenalectomy on neostigmine-induced fasciculations. ( Baker, T; Riker, WF; Sprouse, JS, 1985) |
| "Previous studies have concluded that provocation of fasciculations by neostigmine indicates a lesion of lower motor neurones." | 7.66 | Neostigmine-induced fasciculations--a useful diagnostic test? ( Heijnsbroek, GJ; van Gijn, J, 1983) |
| "Pretreatment with phenytoin, 20 mg/kg, reduced the number of fasciculations to 32% of control without altering contractile strength." | 5.28 | Effects of calcium channel blocking agents on neostigmine-induced fasciculations. ( Dretchen, KL; Henderson, TR; Raines, A, 1989) |
| "The occurrence of fasciculations following administration of agents is a well-known pharmacologic phenomenon." | 5.27 | Drug actions at mammalian motor nerve endings: the suppression of neostigmine-induced fasciculations by vecuronium and isoflurane. ( Baker, T; Stanec, A, 1987) |
| "Neostigmine-induced muscle fasciculations, quantitated as fasciculatory muscle action potentials, served as an indirect in vivo indicator of motor nerve ending (MNE) excitability." | 3.67 | Pharmacologic excitability of rat motor nerve endings: the effect of adrenalectomy on neostigmine-induced fasciculations. ( Baker, T; Riker, WF; Sprouse, JS, 1985) |
| "Previous studies have concluded that provocation of fasciculations by neostigmine indicates a lesion of lower motor neurones." | 3.66 | Neostigmine-induced fasciculations--a useful diagnostic test? ( Heijnsbroek, GJ; van Gijn, J, 1983) |
| "Pretreatment with phenytoin, 20 mg/kg, reduced the number of fasciculations to 32% of control without altering contractile strength." | 1.28 | Effects of calcium channel blocking agents on neostigmine-induced fasciculations. ( Dretchen, KL; Henderson, TR; Raines, A, 1989) |
| "The occurrence of fasciculations following administration of agents is a well-known pharmacologic phenomenon." | 1.27 | Drug actions at mammalian motor nerve endings: the suppression of neostigmine-induced fasciculations by vecuronium and isoflurane. ( Baker, T; Stanec, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heijnsbroek, GJ | 1 |
| van Gijn, J | 1 |
| Okamoto, M | 1 |
| Walewski, JL | 1 |
| Artusio, JF | 1 |
| Riker, WF | 2 |
| Raines, A | 1 |
| Henderson, TR | 1 |
| Dretchen, KL | 1 |
| Baker, T | 2 |
| Stanec, A | 1 |
| Sprouse, JS | 1 |
5 other studies available for neostigmine and Fasciculation
| Article | Year |
|---|---|
Neostigmine-induced fasciculations--a useful diagnostic test?
Topics: Adult; Aged; Fasciculation; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Neostigmin | 1983 |
Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.
Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Cholinesterase Inhibitors; Curare; Dose-Response | 1992 |
Effects of calcium channel blocking agents on neostigmine-induced fasciculations.
Topics: Animals; Calcium Channel Blockers; Electric Stimulation; Facial Muscles; Fasciculation; Male; Neosti | 1989 |
Drug actions at mammalian motor nerve endings: the suppression of neostigmine-induced fasciculations by vecuronium and isoflurane.
Topics: Animals; Cats; Fasciculation; Isoflurane; Motor Neurons; Muscles; Neostigmine; Nerve Endings; Vecuro | 1987 |
Pharmacologic excitability of rat motor nerve endings: the effect of adrenalectomy on neostigmine-induced fasciculations.
Topics: Action Potentials; Adrenal Cortex Hormones; Adrenalectomy; Animals; Electrolytes; Fasciculation; Mal | 1985 |