Page last updated: 2024-10-31

neostigmine and Diaphragmatic Paralysis

neostigmine has been researched along with Diaphragmatic Paralysis in 14 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Research Excerpts

ExcerptRelevanceReference
" Low dosage must be employed and repeated administration avoided."1.31Is vecuronium toxicity abolished by hemodialysis? A case report. ( Borsa, S; Pignataro, A; Pozzato, M; Quarello, F; Rollino, C; Vallero, A; Visetti, E, 2000)
"Clonidine pretreatment (0."1.26Mechanism of the clonidine-induced protection against acetylcholinesterase inhibitor toxicity. ( Buccafusco, JJ, 1982)
"This respiratory paralysis caused by ETX was reversible and of long duration (10-20 hour)."1.26Effect of erabutoxin on respiration of rabbits. ( Murai, S; Ogura, Y, 1977)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's2 (14.29)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Wijdicks, EFM1
Donati, F1
Bawaskar, HS1
Bawaskar, PH2
Cassel, J1
Staehr-Rye, AK1
Nielsen, CV1
Gätke, MR1
Debaene, B1
Meistelman, C1
Plaud, B1
Buccafusco, JJ1
Adler, M1
Scovill, J1
Parker, G1
Lebeda, FJ1
Piotrowski, J1
Deshpande, SS1
Litman, RS1
Younan, MM1
Patt, RB1
Ward, DS1
Rollino, C1
Visetti, E1
Borsa, S1
Pignataro, A1
Pozzato, M1
Vallero, A1
Quarello, F1
Murai, S1
Ogura, Y1
McLaughlin, AP1
Altwein, JE1
Kessler, WO1
Gittes, RF1
Sorokin, M1
Prazák, M1
Placák, B1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Sugammadex Versus Neostigmine During Neuromuscular Blockade Reversal in Outpatient Surgeries - An Evaluation of Clinical and Associated Health Care Cost[NCT03579589]Phase 140 participants (Actual)Interventional2018-08-15Completed
Assessment of Residual Paralysis in Patients Who Receive Mini-dose Atracurium During Supraglottic Airway Insertion[NCT02673853]337 participants (Actual)Observational2016-02-29Completed
The Effectiveness of Neostigmine on the Recovery of Rocuronium-Induced Neuromuscular Blockade: A Comparison Between Partial Dose and TOF Ratio-Based Adjustment Dose[NCT03058263]Phase 1/Phase 266 participants (Actual)Interventional2016-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for neostigmine and Diaphragmatic Paralysis

ArticleYear
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
[Indications and clinical use of sugammadex].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28 Suppl 2

    Topics: Algorithms; Androstanols; Anesthesia Recovery Period; Clinical Trials, Phase III as Topic; Contraind

2009
[Sugammadex: something new to improve patient safety or simply a gadget?].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28 Suppl 2

    Topics: Androstanols; Anesthesia Recovery Period; Atracurium; Cost-Benefit Analysis; Drug Approval; Electrod

2009

Other Studies

11 other studies available for neostigmine and Diaphragmatic Paralysis

ArticleYear
Breaking Down Myasthenic Crisis.
    Neurocritical care, 2020, Volume: 32, Issue:3

    Topics: Cholinesterase Inhibitors; Deglutition Disorders; Emergencies; History, 17th Century; History, 18th

2020
Premonitory signs and symptoms of envenoming by common krait (Bungarus caeruleus).
    Tropical doctor, 2014, Volume: 44, Issue:2

    Topics: Adult; Animals; Atropine; Autonomic Nervous System Diseases; Bulbar Palsy, Progressive; Bungarus; Ch

2014
Use of neuromuscular monitoring to detect prolonged effect of succinylcholine or mivacurium: three case reports.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Accelerometry; Aged; Antidotes; Apnea; Appendicitis; Butyrylcholinesterase; Cholecystectomy, Laparos

2014
Mechanism of the clonidine-induced protection against acetylcholinesterase inhibitor toxicity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Clonidine; Drug Interactions; Male; Mice;

1982
Antagonism of botulinum toxin-induced muscle weakness by 3,4-diaminopyridine in rat phrenic nerve-hemidiaphragm preparations.
    Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:4

    Topics: Aminopyridines; Animals; Botulinum Toxins; Calcium Channel Blockers; Diaphragm; In Vitro Techniques;

1995
Postoperative recurrent paralysis in an infant after mivacurium infusion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:8

    Topics: Female; Humans; Infant; Infusions, Intravenous; Isoquinolines; Mivacurium; Muscle Contraction; Neost

1994
Is vecuronium toxicity abolished by hemodialysis? A case report.
    Artificial organs, 2000, Volume: 24, Issue:5

    Topics: Cholinesterase Inhibitors; Female; Graft Rejection; Humans; Kidney Transplantation; Middle Aged; Mus

2000
Effect of erabutoxin on respiration of rabbits.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:5

    Topics: Animals; Blood Pressure; Edrophonium; Elapid Venoms; Erabutoxins; Female; Heart Rate; Male; Morpholi

1977
Hazards of gallamine administration in patients with renal failure.
    The Journal of urology, 1972, Volume: 108, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Blood Urea Nitrogen; Duodenal Ulcer; Female; G

1972
Puffer fish poisoning.
    The Medical journal of Australia, 1973, May-12, Volume: 1, Issue:19

    Topics: Animals; Fishes, Poisonous; Foodborne Diseases; Humans; Male; Neostigmine; Respiratory Paralysis

1973
Postoperative care after thymectomy for myasthenia gravis.
    International surgery, 1969, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Aged; Ambenonium Chloride; Child; Female; Humans; Male; Middle Aged; Myasthenia G

1969