neostigmine has been researched along with Critical Illness in 7 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Critical illness-related colonic ileus (CIRCI) is characterized by the non-passage of stools in critically ill patients as a result of the absence of prokinetic movements of the colon, while the upper gastrointestinal tract functions properly and mechanical ileus is absent: We investigated whether neostigmine resulted in defecation in patients with CIRCI." | 9.09 | Neostigmine resolves critical illness-related colonic ileus in intensive care patients with multiple organ failure--a prospective, double-blind, placebo-controlled trial. ( Bosman, RJ; Oudemans-van Straaten, HM; Stoutenbeek, CP; van der Spoel, JI; Zandstra, DF, 2001) |
| "Constipation is a common complication of amyotrophic lateral sclerosis (ALS), especially as the disease progresses." | 5.33 | Neostigmine: an alternative treatment for constipation. ( Fu, A, 2005) |
| "Critical illness-related colonic ileus (CIRCI) is characterized by the non-passage of stools in critically ill patients as a result of the absence of prokinetic movements of the colon, while the upper gastrointestinal tract functions properly and mechanical ileus is absent: We investigated whether neostigmine resulted in defecation in patients with CIRCI." | 5.09 | Neostigmine resolves critical illness-related colonic ileus in intensive care patients with multiple organ failure--a prospective, double-blind, placebo-controlled trial. ( Bosman, RJ; Oudemans-van Straaten, HM; Stoutenbeek, CP; van der Spoel, JI; Zandstra, DF, 2001) |
| "Here, we report a case of cardiac arrest complicating neostigmine use in a 16-year-old woman with cerebral palsy who was being treated in the intensive care unit after orthopaedic surgery." | 1.37 | Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient. ( Maher, L; Young, PJ, 2011) |
| "Constipation is a common complication of amyotrophic lateral sclerosis (ALS), especially as the disease progresses." | 1.33 | Neostigmine: an alternative treatment for constipation. ( Fu, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Rahat-Dahmardeh, A | 1 |
| Saneie-Moghadam, S | 1 |
| Khosh-Fetrat, M | 1 |
| Guardiola, B | 1 |
| Llompart-Pou, JA | 1 |
| Ibáñez, J | 1 |
| Raurich, JM | 1 |
| Keller, J | 1 |
| Layer, P | 1 |
| Baradari, AG | 1 |
| Khajavi, MR | 1 |
| Firouzian, A | 1 |
| Alipour, A | 1 |
| Daneshpour, H | 1 |
| Panahi, Y | 1 |
| Sahebkar, A | 1 |
| Maher, L | 1 |
| Young, PJ | 1 |
| Fu, A | 1 |
| van der Spoel, JI | 1 |
| Oudemans-van Straaten, HM | 1 |
| Stoutenbeek, CP | 1 |
| Bosman, RJ | 1 |
| Zandstra, DF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Safety and Efficacy of Different Routes of Neostigmine Administration for Acute Colonic Pseudo Obstruction: a Prospective Randomized Trial[NCT04951726] | Phase 4 | 90 participants (Anticipated) | Interventional | 2022-02-04 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for neostigmine and Critical Illness
| Article | Year |
|---|---|
[Acute colonic pseudo-obstruction: Ogilvie syndrome].
Topics: Colonic Pseudo-Obstruction; Contrast Media; Critical Care; Critical Illness; Decompression, Surgical | 2015 |
3 trials available for neostigmine and Critical Illness
| Article | Year |
|---|---|
Comparing the Effect of Neostigmine and Metoclopramide on Gastric Residual Volume of Mechanically Ventilated Patients in Intensive Care Unit: A Double-Blind Randomized Clinical Trial.
Topics: Antiemetics; Critical Illness; Double-Blind Method; Female; Gastric Emptying; Humans; Intensive Care | 2021 |
Effects of combined prokinetic administration on gastric emptying in critically ill patients.
Topics: Adult; Critical Illness; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Double- | 2017 |
Neostigmine resolves critical illness-related colonic ileus in intensive care patients with multiple organ failure--a prospective, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Criti | 2001 |
3 other studies available for neostigmine and Critical Illness
| Article | Year |
|---|---|
Prophylaxis Versus Treatment Use of Laxative for Paralysis of Lower Gastrointestinal Tract in Critically Ill Patients.
Topics: Adult; Aged; Constipation; Critical Illness; Defecation; Drug Administration Schedule; Enema; Female | 2016 |
Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient.
Topics: Adolescent; Bradycardia; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Critical Illness; Fe | 2011 |
Neostigmine: an alternative treatment for constipation.
Topics: Aged; Amyotrophic Lateral Sclerosis; Colonic Pseudo-Obstruction; Constipation; Critical Illness; Fem | 2005 |