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neostigmine and Complication, Postoperative

neostigmine has been researched along with Complication, Postoperative in 173 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Research Excerpts

ExcerptRelevanceReference
"For patients accepted colon carcinoma surgery, neostigmine did not significantly reduce the incidence of POD, postoperative mortality and postoperative hospital stay, while it indeed reduced the extubating time, PACU time and the incidence of POPCs."9.51The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial. ( Bi, Y; Deng, X; Dong, R; Guo, Y; Lin, X; Lin, Y; Liu, F; Wang, B, 2022)
"This study aimed to assess the effects of sugammadex and neostigmine/atropine on postoperative cognitive dysfunction (POCD) in adult patients after elective surgery."9.24Effect of sugammadex versus neostigmine/atropine combination on postoperative cognitive dysfunction after elective surgery. ( Batistaki, C; Kostopanagiotou, G; Lyrakos, G; Matsota, P; Riga, M; Zafeiropoulou, F, 2017)
" The current trial was aimed to compare between sugammadex and neostigmine concerning the recovery time from neuromuscular blockade."9.24A comparison of sugammadex and neostigmine for reversal of rocuronium-induced neuromuscular blockade in children. ( Ammar, AS; Kasemy, ZA; Mahmoud, KM, 2017)
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."9.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)
"Neostigmine may increase postoperative nausea and vomiting."9.08Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. ( Halonen, P; Hovorka, J; Korttila, K; Nelskylä, K; Paatero, H; Sarvela, J; Soikkeli, A; Yli-Hankala, A, 1997)
"A double-blind and randomized clinical trial, which included 48 patients with postoperative intestinal paralysis on the third day after laparotomy, demonstrated no difference between treatment with ceruletide (0."9.06Ceruletide and neostigmine in postoperative intestinal paralysis. A double-blind clinical controlled trial. ( Hagen, K; Madsen, PV; Olsen, O, 1986)
" The authors hypothesized that the choice of neuromuscular blockade reversal (neostigmine vs."7.96Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis. ( Bardia, A; Bartels, K; Bash, LD; Colquhoun, DA; Dubovoy, TZ; Kheterpal, S; Mathis, MR; McCormick, PJ; Saager, L; Schonberger, RB; Shah, NJ; Shanks, AM; Soto, RG; Vaughn, MT, 2020)
"Prospective observational series of consecutive patients scheduled for laparoscopic bariatric surgery in whom neuromuscular blockade was reverted with sugammadex were compared with a historical matched cohort of patients reverted with neostigmines."7.80Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine. ( Cabrera, A; Camprubí, I; Ferreres, E; Llauradó, S; Sabaté, A, 2014)
"Starting the early intake of nutrition with neostigmine in the postoperative period reduced the postoperative ileus and increased the healing of colon anastomoses (Tab."7.77The effect of neostigmine on postoperative ileus and the healing of colon anastomoses. ( Durgun, V; Ekci, B; Emirleroglu, M, 2011)
" Sugammadex exhibits advantages over indirect reversal agent acetylcholinesterase inhibitor neostigmine with less adverse effects."5.72Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate. ( Chang, HC; Lee, MJ; Lee, SO; Liu, SY; Wong, CS, 2022)
" Sugammadex reversal of neuromuscular blockade is rapid and complete, and there appear to be fewer postoperative complications than with neostigmine."5.51Comparison of the effects of neostigmine and sugammadex on postoperative residual curarization and postoperative pulmonary complications by means of diaphragm and lung ultrasonography: a study protocol for prospective double-blind randomized controlled tr ( Chen, Y; Yi, J; Zhang, YG; Zhang, YL, 2022)
"For patients accepted colon carcinoma surgery, neostigmine did not significantly reduce the incidence of POD, postoperative mortality and postoperative hospital stay, while it indeed reduced the extubating time, PACU time and the incidence of POPCs."5.51The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial. ( Bi, Y; Deng, X; Dong, R; Guo, Y; Lin, X; Lin, Y; Liu, F; Wang, B, 2022)
"Post-operative ileus is common after abdominal surgeries."5.51Case report series of a novel application of neostigmine to successfully relieve refractory ileus status post-pediatric orthotopic liver transplantation. ( Balakrishnan, B; Hong, JC; Petersen, PC; Vitola, B, 2019)
"We concluded that sugammadex is more effective at reducing the incidence of PPCs including pneumonia, atelectasis, NIV and reintubation compared with neostigmine."5.41Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis. ( Liang, P; Liu, HM; Yu, H; Zuo, YD, 2023)
"The incidence of postoperative nausea and vomiting (PONV) in PACU was higher in neostigmine-reversed than sugammadex-reversed patients (21."5.40Retrospective investigation of postoperative outcome after reversal of residual neuromuscular blockade: sugammadex, neostigmine or no reversal. ( De Mel, A; Falke, L; Gillies, E; Greenaway, M; Johnston, F; Ledowski, T; Phillips, M; Tiong, WS, 2014)
"Neostigmine has been used in some cases of refractory constipation in critically ill adults."5.37Neostigmine in the treatment of refractory constipation in critically ill children. ( Botrán, M; García, A; González, R; López-Herce, J; Solana, MJ; Urbano, J, 2011)
"This study aimed to assess the effects of sugammadex and neostigmine/atropine on postoperative cognitive dysfunction (POCD) in adult patients after elective surgery."5.24Effect of sugammadex versus neostigmine/atropine combination on postoperative cognitive dysfunction after elective surgery. ( Batistaki, C; Kostopanagiotou, G; Lyrakos, G; Matsota, P; Riga, M; Zafeiropoulou, F, 2017)
" The current trial was aimed to compare between sugammadex and neostigmine concerning the recovery time from neuromuscular blockade."5.24A comparison of sugammadex and neostigmine for reversal of rocuronium-induced neuromuscular blockade in children. ( Ammar, AS; Kasemy, ZA; Mahmoud, KM, 2017)
"Neostigmine may increase postoperative nausea and vomiting."5.08Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. ( Halonen, P; Hovorka, J; Korttila, K; Nelskylä, K; Paatero, H; Sarvela, J; Soikkeli, A; Yli-Hankala, A, 1997)
" In this randomized, double-blind, placebo-controlled study of 113 healthy children who had received mivacurium as part of a standardized anesthetic regimen, we compared the incidence of postoperative complications after spontaneous recovery and after the use of neostigmine-glycopyrrolate or edrophonium-atropine."5.08Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children. ( McCulloch, DA; Safavi, FZ; Tan, TS; Watcha, MF; White, PF, 1995)
" morphine 100 microg, but with a high incidence of nausea and vomiting."5.08The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia. ( Chin, YJ; Chung, CJ; Kim, JS; Park, HS, 1998)
"A double-blind and randomized clinical trial, which included 48 patients with postoperative intestinal paralysis on the third day after laparotomy, demonstrated no difference between treatment with ceruletide (0."5.06Ceruletide and neostigmine in postoperative intestinal paralysis. A double-blind clinical controlled trial. ( Hagen, K; Madsen, PV; Olsen, O, 1986)
"In 2020, the Sugammadex vs Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER) study provided evidence for the first time that use of sugammadex is associated with fewer postoperative pulmonary complications than use of neostigmine."4.31How robust are the STRONGER and STIL-STRONGER studies? ( Blobner, M; Hunter, JM; Ulm, K, 2023)
"Gastrografin and combined use of gastrografin and neostigmine are effective and viable methods for postoperative ileus cases."4.31The efficacy and results of medical treatment in postoperative ileus. ( Alkan, S; Cakir, M; Duyan, AG; Sentiurk, M; Varman, A, 2023)
" The authors hypothesized that the choice of neuromuscular blockade reversal (neostigmine vs."3.96Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis. ( Bardia, A; Bartels, K; Bash, LD; Colquhoun, DA; Dubovoy, TZ; Kheterpal, S; Mathis, MR; McCormick, PJ; Saager, L; Schonberger, RB; Shah, NJ; Shanks, AM; Soto, RG; Vaughn, MT, 2020)
"Inappropriate dosing of neostigmine for antagonism of neuromuscular blockade has been associated with postoperative pulmonary complications."3.88Implementation of a new strategy to improve the peri-operative management of neuromuscular blockade and its effects on postoperative pulmonary complications. ( Agarwala, AV; Chitilian, HV; Doney, AB; Eikermann, M; Houle, TT; Ng, PY; Ramachandran, SK; Rudolph, MI; Timm, FP, 2018)
"Prospective observational series of consecutive patients scheduled for laparoscopic bariatric surgery in whom neuromuscular blockade was reverted with sugammadex were compared with a historical matched cohort of patients reverted with neostigmines."3.80Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine. ( Cabrera, A; Camprubí, I; Ferreres, E; Llauradó, S; Sabaté, A, 2014)
"Neostigmine reversal did not affect oxygenation but was associated with increased atelectasis."3.80Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study. ( Doran, ME; Eikermann, M; Hoang, AH; Igumenshcheva, A; MacDonald, T; Malviya, SA; Meyer, MJ; Sasaki, N; Stanislaus, AB, 2014)
"Starting the early intake of nutrition with neostigmine in the postoperative period reduced the postoperative ileus and increased the healing of colon anastomoses (Tab."3.77The effect of neostigmine on postoperative ileus and the healing of colon anastomoses. ( Durgun, V; Ekci, B; Emirleroglu, M, 2011)
" The most likely cause was the return of muscle paralysis after the apparent antagonism of tubocurarine by neostigmine (recurarization)."3.65Renal failure and postoperative respiratory failure: recurarization? ( Cullen, DJ; Miller, RD, 1976)
"Residual neuromuscular block has been associated with postoperative pulmonary complications."2.94Randomised controlled trial of sugammadex or neostigmine for reversal of neuromuscular block on the incidence of pulmonary complications in older adults undergoing prolonged surgery. ( Aziz, MF; Higgins, JR; Tekkali, P; Togioka, BM; Treggiari, MM; Yanez, D, 2020)
"Neostigmine was intravenously injected in the post-anesthesia care unit (PACU) according to the train-of-four ratio (TOFR) T4/T1."2.94The effects of neostigmine on postoperative cognitive function and inflammatory factors in elderly patients - a randomized trial. ( Deng, C; Feng, Y; Sun, D; Sun, Z; Yang, L; Zhu, B, 2020)
"Median [interquartile range (IQR)] atelectasis area was 9."2.90Effects of neuromuscular block reversal with sugammadex versus neostigmine on postoperative respiratory outcomes after major abdominal surgery: a randomized-controlled trial. ( Alday, E; Alvarez, C; Mata, E; Muñoz, M; Planas, A, 2019)
"Electroacupuncture combined with acupoint injection has a satisfied therapeutic effect for treatment of EPISBO."2.75[Clinical observation on electroacupuncture combined with acupoint injection for treatment of early postoperative inflammatory intestinal obstruction]. ( Ding, KY; Guan, J; Shen, LP, 2010)
"Monitoring for pain, sedation, postoperative nausea/vomiting, dizziness, and pruritus was performed by anesthesiologists blinded to the study allocation."2.71Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine. ( Acharya, A; Kumar, P; Pan, AK; Rudra, A, 2005)
" Peripherally acting acetylcholinesterase inhibitors such as neostigmine should then only be administered when indicated and dosed based on results of the train-of-four ratio."2.66The effects of acetylcholinesterase inhibitors on morbidity after general anesthesia and surgery. ( Eikermann, M; Schaefer, MS; Shay, D; Wongtangman, K, 2020)
"Neostigmine, 0."2.66Neostigmine in postoperative intestinal paralysis. A double-blind, clinical, controlled trial. ( Myrhöj, T; Olsen, O; Wengel, B, 1988)
" Patients treated with Ceruletide (n = 30, dosage of Ceruletide 2 ng/kg/min."2.65[Treatment of intestinal atony following gynecologic operations. Study on the effectiveness and tolerance of ceruletide]. ( Baur, M; Heinrich, D; Kubli, F; Schmid, H; Schulz-Wendtland, R; von Fournier, D, 1984)
"Patients with obstructive sleep apnea (OSA) may be at higher risk of complications related to the use of NMBD."2.58Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review. ( Chung, F; Hafeez, KR; Nagappa, M; Singh, M; Tuteja, A; Wong, DT; Wong, J, 2018)
"Even small degrees of residual neuromuscular blockade, i."2.55[Residual neuromuscular blockade]. ( Fuchs-Buder, T; Schmartz, D, 2017)
"The management of neuromuscular blocks in day case surgery requests a comprehensive approach that should include an adequate dosing of the muscle relaxant, quantitative objective monitoring, and a sufficient and appropriate reversal."2.50Management of neuromuscular blockade in ambulatory patients. ( Schreiber, JU, 2014)
" Sugammadex exhibits advantages over indirect reversal agent acetylcholinesterase inhibitor neostigmine with less adverse effects."1.72Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate. ( Chang, HC; Lee, MJ; Lee, SO; Liu, SY; Wong, CS, 2022)
" Inappropriate dosing of neostigmine can lead to post-operative respiratory complications."1.62Identifying high dose neostigmine as a risk factor for post-operative respiratory complications: a case-control study. ( Al-Zarah, M; Drzymalski, DM; Hall III, RR; Quraishi, SA; Ranjan, S, 2021)
"Post-operative ileus is common after abdominal surgeries."1.51Case report series of a novel application of neostigmine to successfully relieve refractory ileus status post-pediatric orthotopic liver transplantation. ( Balakrishnan, B; Hong, JC; Petersen, PC; Vitola, B, 2019)
"Complete avoidance of residual neuromuscular blockade (RNMB) during the postoperative period has not yet been achieved in current anesthesia practice."1.51Usefulness of intra-operative neuromuscular blockade monitoring and reversal agents for postoperative residual neuromuscular blockade: a retrospective observational study. ( Domenech, G; Fornari, GG; García Guzzo, ME; Kampel, MA; Novas, DS; Terrasa, SA, 2019)
" We tested whether a protocol for the management of neuromuscular block that specified appropriate dosing and optimal neostigmine reversal was associated with a reduction in postoperative residual neuromuscular block."1.48Management of rocuronium neuromuscular block using a protocol for qualitative monitoring and reversal with neostigmine. ( Bhananker, SM; Cain, KC; Ng, IC; Thilen, SR; Treggiari, MM, 2018)
"Neostigmine treatment was required for 1 patient in the intensive care unit setting, and 3 patients were managed conservatively without complications."1.46The Potentially Fatal Ogilvie's Syndrome in Lateral Transpsoas Access Surgery: A Multi-Institutional Experience with 2930 Patients. ( Beckman, JM; Januszewski, J; Kanter, AS; Keem, SK; Oskuian, RJ; Smith, W; Taylor, W; Uribe, JS, 2017)
"Neostigmine was associated with a dose-dependent increase in the risk of postoperative respiratory complications (OR, 1."1.42Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications. ( Diaz-Gil, D; Eikermann, M; Farhan, HN; Kurth, T; Ladha, KS; McLean, DJ, 2015)
"The incidence of postoperative nausea and vomiting (PONV) in PACU was higher in neostigmine-reversed than sugammadex-reversed patients (21."1.40Retrospective investigation of postoperative outcome after reversal of residual neuromuscular blockade: sugammadex, neostigmine or no reversal. ( De Mel, A; Falke, L; Gillies, E; Greenaway, M; Johnston, F; Ledowski, T; Phillips, M; Tiong, WS, 2014)
"Neostigmine has been used in some cases of refractory constipation in critically ill adults."1.37Neostigmine in the treatment of refractory constipation in critically ill children. ( Botrán, M; García, A; González, R; López-Herce, J; Solana, MJ; Urbano, J, 2011)
" It is suggested that the dosage of anticholinergic agents given with neostigmine could be reduced in elderly patients in comparison to that in younger patients."1.27Antagonism of neuromuscular block in the elderly. A comparison of atropine and glycopyrronium in a mixture with neostigmine. ( Mirakhur, RK, 1985)
"Ampullary stenosis was confirmed in all patients who subsequently underwent sphincteroplasty."1.26Duodenoscopy and endoscopic pancreatography in patients with postive morphine prostigmine tests. ( Capobianco, AG; Frager, SH; Gregg, JA; McCartney, AJ; Milano, AF; Santoro, BT; Taddeo, AE, 1977)
"Neostigmine may produce this effect by causing contractions of the gut musculature or by vasoconstriction of the blood vessels to the suture line, resulting in local ischaemia."1.25Effect of neostigmine on integrity of ileorectal anastomoses. ( Bell, CM; Lewis, CB, 1968)

Research

Studies (173)

TimeframeStudies, this research(%)All Research%
pre-199066 (38.15)18.7374
1990's17 (9.83)18.2507
2000's11 (6.36)29.6817
2010's45 (26.01)24.3611
2020's34 (19.65)2.80

Authors

AuthorsStudies
Beltran, RJ1
Mpody, C1
Nafiu, OO1
Tobias, JD1
Carron, M2
Tessari, I1
Linassi, F2
Ranjan, S1
Hall III, RR1
Al-Zarah, M1
Quraishi, SA1
Drzymalski, DM1
Zhang, YG1
Chen, Y2
Zhang, YL1
Yi, J1
Chang, HC1
Liu, SY1
Lee, MJ1
Lee, SO1
Wong, CS1
Yu, Y1
Wang, H1
Bao, Q1
Zhang, T1
Chen, B1
Ding, J1
Colquhoun, DA2
Vaughn, MT2
Bash, LD2
Janda, A1
Shah, N1
Ghaferi, A1
Sjoding, M1
Mentz, G1
Kheterpal, S2
Sharma, A1
Campos, JH1
Togioka, BM2
Schenning, KJ1
Liu, F1
Lin, X1
Lin, Y1
Deng, X2
Guo, Y2
Wang, B1
Dong, R1
Bi, Y1
Traeger, L1
Hall, TD1
Bedrikovetski, S2
Kroon, HM2
Dudi-Venkata, NN2
Moore, JW2
Sammour, T2
Yang, JL1
Chen, KB1
Shen, ML1
Hsu, WT1
Lai, YW1
Hsu, CM1
Blobner, M1
Hunter, JM2
Ulm, K1
Suleiman, A1
Munoz-Acuna, R1
Azimaraghi, O1
Houle, TT2
Chen, G1
Rupp, S1
Witt, AS1
Azizi, BA1
Ahrens, E1
Shay, D2
Wongtangman, K2
Wachtendorf, LJ1
Tartler, TM1
Eikermann, M9
Schaefer, MS2
Sidebotham, D1
Frampton, C1
Yu, H2
Zuo, Y1
Xu, Z1
Zhao, D1
Yue, J1
Liu, L1
Huang, J1
Liang, P2
Liu, H1
Luo, R1
Cao, S1
Zheng, B1
Ye, L1
Zhang, W1
Tamburini, E1
Ieppariello, G1
Liu, HM1
Zuo, YD1
Díaz-Cambronero, Ó1
Mazzinari, G1
Errando, CL1
Garutti, I1
Gurumeta, AA1
Serrano, AB1
Esteve, N1
Montañes, MV1
Neto, AS1
Hollmann, MW1
Schultz, MJ1
Argente Navarro, MP1
Alkan, S1
Cakir, M1
Sentiurk, M1
Varman, A1
Duyan, AG1
Ji, Y1
Yuan, H1
Zhang, X1
Wu, F1
Tang, W1
Lu, Z1
Huang, C1
Bai, YX1
Han, JJ1
Liu, J2
Li, X1
Xu, ZZ1
Lv, Y1
Liu, KX1
Wu, QP1
Domenech, G1
Kampel, MA1
García Guzzo, ME1
Novas, DS1
Terrasa, SA1
Fornari, GG1
Petersen, PC1
Balakrishnan, B1
Vitola, B1
Hong, JC1
Korkmaz, MO1
Sayhan, H1
Guven, M1
Scheffenbichler, FT1
Rudolph, MI2
Friedrich, S1
Althoff, FC1
Xu, X1
Spicer, AC1
Patrocínio, M1
Ng, PY2
Deng, H1
Anderson, TA1
Oh, TK2
Ryu, JH1
Nam, S1
Oh, AY2
Yanez, D1
Aziz, MF1
Higgins, JR1
Tekkali, P1
Treggiari, MM2
Dubovoy, TZ1
Shah, NJ1
Shanks, AM1
Mathis, MR1
Soto, RG1
Bardia, A1
Bartels, K1
McCormick, PJ1
Schonberger, RB1
Saager, L2
Leslie, K1
Min, BH1
Song, IA1
Jeon, YT1
Zhu, B1
Sun, D1
Yang, L1
Sun, Z1
Feng, Y1
Deng, C1
Brull, SJ1
Murphy, GS1
Ledowski, T2
Szabó-Maák, Z1
Loh, PS1
Turlach, BA1
Yang, HS1
de Boer, HD1
Asztalos, L1
Shariffuddin, II1
Chan, L1
Fülesdi, B1
Piskin, O1
Altinsoy, B1
Cimencan, M1
Aydin, BG1
Okyay, D1
Kucukosman, G1
Tascilar, O1
Sarikaya, S1
Ayoglu, H1
Choi, ES1
Koo, BW1
Hwang, JW1
Han, JW1
Seo, KS1
Ahn, SH1
Jeong, WJ1
Fuchs-Buder, T3
Schmartz, D1
Batistaki, C1
Riga, M1
Zafeiropoulou, F1
Lyrakos, G1
Kostopanagiotou, G1
Matsota, P1
Belcher, AW1
Leung, S1
Cohen, B1
Yang, D1
Mascha, EJ1
Turan, A1
Ruetzler, K1
Chitilian, HV1
Timm, FP1
Agarwala, AV1
Doney, AB1
Ramachandran, SK1
Hafeez, KR1
Tuteja, A1
Singh, M1
Wong, DT1
Nagappa, M1
Chung, F1
Wong, J1
Thilen, SR1
Ng, IC1
Cain, KC1
Bhananker, SM1
Alday, E1
Muñoz, M1
Planas, A1
Mata, E1
Alvarez, C1
Xia, R1
Kachru, N1
Tuazon, DM1
Bostan, F1
Fuentes, A1
Meyer, MJ3
Bateman, BT2
Kurth, T3
Donati, F1
Kalb, A1
von Haefen, C1
Sifringer, M1
Tegethoff, A1
Paeschke, N1
Kostova, M1
Feldheiser, A1
Spies, CD1
Della Rocca, G1
Pompei, L1
Pagan DE Paganis, C1
Tesoro, S1
Mendola, C1
Boninsegni, P1
Tempia, A1
Manstretta, S1
Zamidei, L1
Gratarola, A1
Murabito, P1
Fuggiano, L1
DI Marco, P1
Baraka, A2
Falke, L1
Johnston, F1
Gillies, E1
Greenaway, M1
De Mel, A1
Tiong, WS1
Phillips, M1
Llauradó, S1
Sabaté, A1
Ferreres, E1
Camprubí, I1
Cabrera, A1
Amorim, P1
Lagarto, F1
Gomes, B1
Esteves, S1
Bismarck, J1
Rodrigues, N1
Nogueira, M1
Nagella, AB1
Bijapur, MB1
Shreyavathi, S1
Rao, RR1
Sasaki, N2
Malviya, SA1
Stanislaus, AB1
MacDonald, T1
Doran, ME1
Igumenshcheva, A1
Hoang, AH1
Schreiber, JU1
McLean, DJ1
Diaz-Gil, D1
Farhan, HN1
Ladha, KS1
Hermite, L1
Louvier, N1
Hilaire, P1
Orry, D1
Seltzer, S1
Collet, E1
Yu, B1
Ouyang, B1
Ge, S1
Luo, Y1
Li, J1
Ni, D1
Hu, S1
Xu, H1
Min, S1
Li, L1
Ma, Z1
Xie, K1
Miao, C1
Wu, X1
Kopman, AF2
Naguib, M1
Bulka, CM1
Terekhov, MA1
Martin, BJ1
Dmochowski, RR1
Hayes, RM1
Ehrenfeld, JM2
Hinkson, L1
Faensen, AL1
Armbrust, R1
Henrich, W1
Januszewski, J1
Keem, SK1
Smith, W1
Beckman, JM1
Kanter, AS1
Oskuian, RJ1
Taylor, W1
Uribe, JS1
Ammar, AS1
Mahmoud, KM1
Kasemy, ZA1
Bronsert, MR1
Henderson, WG1
Monk, TG1
Richman, JS1
Nguyen, JD1
Sum-Ping, JT1
Mangione, MP1
Higley, B1
Hammermeister, KE1
Takeda, J1
FORD, WJ1
Gómez-Martínez, ML1
Fernández Garijo, P1
Bustamante Munguira, J1
Gómez Herreras, JI1
Beccaria, P1
Cabrini, L1
Garancini, MP1
Colombo, S1
Zeinali, F1
Stulberg, JJ1
Delaney, CP1
Debaene, B1
Meistelman, C1
Plaud, B1
Weingarten, TN1
Hofer, RE1
Milone, M1
Sprung, J1
Shen, LP1
Guan, J1
Ding, KY1
Yu, D1
Chai, W1
Sun, X1
Yao, L1
Emirleroglu, M1
Ekci, B1
Durgun, V1
Karkos, PD1
Srivastava, R1
Kaptanis, S1
Renukaswamy, GM1
González, R1
López-Herce, J1
García, A1
Botrán, M1
Solana, MJ1
Urbano, J1
Hili, S1
Fu, B1
Davis, J1
Fressard, D1
Manent, P1
Gautier, M1
Thevenot, F1
Grosse-Sundrup, M1
Henneman, JP1
Sandberg, WS1
Uribe, JV1
Nguyen, NT1
Martinez, EA1
MCDONALD, I1
REAM, CR1
FELDMAN, SA2
LEVI, JA1
POCTA, J1
UHLIROVA, A1
DAWSON, GR1
HONDA, M1
TAKESHIGE, S1
ISHIKAWA, F1
TOYAMA, F1
JENKINS, LC1
CHANG, J1
GRAVES, HB1
HELBIG, D1
Zank, LM1
Ng, J1
Neuman, GG1
Behm, B1
Stollman, N1
Kumar, P1
Rudra, A1
Pan, AK1
Acharya, A1
Lankarani-Fard, A1
Castle, SC1
Bräutigam, HH1
Netter, KJ1
Rietbrock, N1
Katsumi, M1
Utsunomiya, H1
Nakazawa, T1
Uragami, T1
Okada, M1
Aitkenhead, AR2
Sher, MH1
Mathews, PA1
von Fournier, D1
Baur, M1
Schmid, H1
Schulz-Wendtland, R1
Heinrich, D1
Kubli, F1
Punt-van Manen, JA1
Müller, H1
Kalenda, Z1
Brolin, RE1
Ravitch, MM1
Allwright, GT1
von Sommoggy, S2
Theisinger, W1
Fraunhofer, B1
Ruwart, MJ1
Klepper, MS1
Rush, BD1
Shorten, GD1
Merk, H1
Sieber, T1
Boeke, AJ2
Smith, I1
Williams, PI1
Watcha, MF2
Safavi, FZ1
McCulloch, DA1
Tan, TS1
White, PF2
de Lange, JJ1
van Druenen, B1
Langemeijer, JJ1
Litman, RS1
Younan, MM1
Patt, RB1
Ward, DS1
Huang, CH1
Wang, MJ1
Susetio, L1
Cherng, YG1
Shi, JJ1
Chen, YA1
Chiu, WH1
Orlando, E1
Finelli, F1
Colla, M1
Giotto, E1
Terragni, P1
Olivero, G1
Figueredo, E1
Sánchez, G1
Pérez, J1
Hovorka, J1
Korttila, K1
Nelskylä, K1
Soikkeli, A1
Sarvela, J1
Paatero, H1
Halonen, P1
Yli-Hankala, A1
Chung, CJ1
Kim, JS1
Park, HS1
Chin, YJ1
Herschman, Z1
Tramèr, MR1
Ortiz-Gómez, JR1
Champault, G1
Wiesmeier, R1
Heinkelmann, W1
Birk, M1
Blümel, G1
Muravchick, S1
Owens, WD1
Felts, JA1
Brun, J1
Magnin, F1
Gregg, JA1
Taddeo, AE1
Milano, AF1
McCartney, AJ1
Santoro, BT1
Frager, SH1
Capobianco, AG1
Schuster, G1
Peters, H1
Lynen, FK1
Oduro, KA1
Rho, S1
Dornette, WH1
Viljoen, JF1
Dauchel, J1
Schang, JC1
Kachelhoffer, J1
Eloy, R1
Grenier, JF1
Miller, RD1
Cullen, DJ1
Heijke, SA1
Smith, G1
Key, A1
Constable, PD1
Muir, WW1
Freeman, L1
Hoffsis, GF1
St Jean, G1
Welker, FH1
Kim, JM1
Mangold, J1
Braun, U1
Steiner, A1
Bearth, G1
Gómez Gámez, A1
Sánchez de Badajoz, E1
García Caballero, M1
Gutstein Feldman, D1
Vara Thorbeck, C1
Cody, MW1
Dormon, FM1
King, MJ1
Milazkiewicz, R1
Carli, F1
Deacock, AR1
Olivieri, L1
Pierdominici, S1
Testa, G1
Borzomati, E1
Battisti, G1
Arrabito, G1
Caporale, A1
Giuliani, A1
Myrhöj, T1
Olsen, O2
Wengel, B1
Sibai, AN1
Hamed, M1
Delleh, R1
Eldor, J1
Hoffman, B1
Davidson, JT1
Madsen, PV1
Hagen, K1
Herz, BL1
Carlos, R1
Erill, S1
Cyba-Altunbay, S1
Bauer, J1
Mirakhur, RK1
Madura, JA1
Fiore, AC1
O'Connor, KW1
Lehman, GA1
McCammon, RL1
Roberts-Thomson, IC1
Toouli, J1
Brodsky, JB1
Dechêne, JP1
Desrosiers, R1
Bédard, O1
Anand, JS1
Mehta, RK1
Munshi, CA1
Mulla, DH1
Leibowitz, I1
Draxler, V1
Mimpriss, TJ1
Heimbach, DM1
Crout, JR1
Mieny, CJ1
Cooke, PA1
Solomon, H1
Edwards, FR1
Wilson, A1
Anezaki, T1
Brehm, R1
Janisch, H1
Bell, CM2
Neely, J1
Catchpole, B1
Zhorov, IS1
Michelson, VA1
Krochalev, AA1
Sevadjian, EB1
Richmond, DR1
Smith, DR1
Lewis, CB1
Borchert, K1
Ostfeld, E1
Eliahou, HE1

Clinical Trials (33)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Neostigmine and Sugammadex on Postoperative Residual Curarization and Postoperative Pulmonary Complications Detected by Diaphragm and Lung Ultrasonography: A Study Protocol for Prospective Double-blind Randomized Controlled Tr[NCT05040490]414 participants (Anticipated)Interventional2021-08-31Not yet recruiting
The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications in Patients 70 Years or Older and Scheduled for 3 Hour or Longer Surgery-A Randomized Controlled Trial[NCT02861131]Phase 4200 participants (Actual)Interventional2017-01-24Completed
Diaphragm Ultrasound to Evaluate the Antagonistic Effect of Sugammadex on Rocuronium After Liver Surgery in Patients With Different Liver Child-Pugh Grades[NCT05028088]Phase 499 participants (Anticipated)Interventional2021-07-01Recruiting
Comparison Sugammadex With Neostigmine in Laryngeal Microsurgery.[NCT02330172]44 participants (Actual)Interventional2014-05-31Completed
Comparison of the Effect of Continuous Infusion and Bolus Doses of Rocuronium During Anesthesia for Lumbal Discectomy on Muscle Strength and Quality of Patient Recovery[NCT04236050]80 participants (Actual)Interventional2015-12-31Completed
Comparison of General Anesthesia With Use of Muscle Relaxation and General Anesthesia Without Muscle Relaxation on Recovery of Muscle Strength of the Patients[NCT04760912]60 participants (Anticipated)Interventional2020-04-01Enrolling by invitation
PACU or ICU for Postoperative Care After Major Thoracic and Abdominal Surgery:a Prospective Randomized Clinical Trial[NCT05046925]18,000 participants (Anticipated)Observational2021-10-01Not yet recruiting
Validation of the REPS Prediction Tool to Improve Quality of Perioperative Care[NCT03585400]101,510 participants (Actual)Observational2018-06-29Completed
Importance of Understanding Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal Agents[NCT03585348]265,537 participants (Actual)Observational2018-06-29Completed
Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium: A Pharmacodynamic Modelling Study[NCT03737942]60 participants (Anticipated)Observational2018-11-15Recruiting
Incidence and Severity of Residual Neuromuscular Blockade With Application of a Protocol for Paralysis and Neostigmine Reversal of Rocuronium[NCT02660398]Phase 478 participants (Actual)Interventional2016-01-31Completed
Electromyographic Activity of the Diaphragm and of the Rectus Abdominis and Intercostal Muscles During Neostigmine, Sugammadex, or Neostigmine-sugammadex Enhanced Recovery After Neuromuscular Blockade With Rocuronium. A Randomised Controlled Study in Heal[NCT02403063]Phase 418 participants (Actual)Interventional2015-09-30Completed
The Effect of Sugammadex Versus Neostigmine During Neuromuscular Blockade Reversal in Outpatient Surgeries - An Evaluation of Clinical and Associated Health Care Cost[NCT03579589]Phase 140 participants (Actual)Interventional2018-08-15Completed
Assessment of Residual Paralysis in Patients Who Receive Mini-dose Atracurium During Supraglottic Airway Insertion[NCT02673853]337 participants (Actual)Observational2016-02-29Completed
The Effectiveness of Neostigmine on the Recovery of Rocuronium-Induced Neuromuscular Blockade: A Comparison Between Partial Dose and TOF Ratio-Based Adjustment Dose[NCT03058263]Phase 1/Phase 266 participants (Actual)Interventional2016-10-31Completed
A Randomized, Blinded-assessor, Single Center Study to Determine if Administration of Sugammadex, When Used to Reverse Deep Neuromuscular Blockade (NMB) After Open Abdominal Surgery, Impacts Hospital Efficiency[NCT02860507]Phase 450 participants (Actual)Interventional2016-08-31Completed
Comparing Deep Neuromuscular Block and Moderate Neuromuscular Block in Patients Undergoing Laparoscopic Gynaecological Surgeries: Impact on Surgical Satisfaction of Operating Conditions and Patient Satisfaction[NCT02794714]Phase 40 participants (Actual)Interventional2016-06-30Withdrawn (stopped due to unresolved budget issues)
The VivaSight Double Lumen Tube Versus Conventional Double Lumen Tube in Thoracic Surgical Patients[NCT03690284]50 participants (Actual)Interventional2019-06-19Completed
Effects of Postoperative Residual Paralysis on Costs of Hospital Care, Length of Hospitalization and Intensive Care Unit Admission Rate[NCT01718860]3,000 participants (Anticipated)Observational2011-04-30Active, not recruiting
Residual Curarization and Its Incidence at Tracheal Extubation in China[NCT01871064]1,571 participants (Actual)Observational2012-12-31Completed
The Effect of Intraoperative Neuromuscular Blockade on Postoperative Atelectasis in Patients Undergoing Thoracic Surgery With One Lung Ventilation: Moderate vs. Deep Block[NCT03503565]118 participants (Actual)Observational2018-10-11Completed
Combined General and Spinal Anesthesia vs. Combined General and Spinal Anesthesia With Neuromuscular Blockade for Operative Repair of Hip Fractures[NCT03226080]Phase 40 participants (Actual)Interventional2017-07-19Withdrawn (stopped due to Study terminated with IRB on 20Feb2019 due to lack of enrollment.)
Sugammadex Versus Neostigmine in Pediatric Day-case Cancer Surgery[NCT03996655]Phase 480 participants (Anticipated)Interventional2019-06-30Not yet recruiting
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant[NCT02819089]100 participants (Anticipated)Interventional2016-05-31Recruiting
Comparison of Two Different Anesthetic Techniques on Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position: A Prospective Randomized Clinical Trial[NCT03572517]65 participants (Actual)Interventional2017-09-01Completed
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty: A Randomized, Controlled Trial[NCT05601674]76 participants (Actual)Interventional2022-11-04Completed
Visualization of Regional Lung Ventilation During Neostigmine or Sugammadex Enhanced Recovery From Moderate Residual Neuromuscular Blockade in the Anaesthetized Rat Using Functional Respiratory Imaging[NCT02284412]Phase 413 participants (Actual)Interventional2014-12-31Completed
Optimal Dose of Combination of Rocuronium and Cisatracurium: A Randomized Double-blinded Clinical Trial[NCT02495038]81 participants (Actual)Interventional2014-03-31Completed
A Prospective Randomized Control Trial of The Effectiveness of Entereg as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT02742181]Phase 314 participants (Actual)Interventional2015-12-02Terminated (stopped due to terminated due to lack of enrollment)
A Randomized Trial of Alvimopan for the Reduction of Ileus After Long Posterior Spinal Fusion[NCT02218190]31 participants (Actual)Interventional2014-08-31Completed
A Prospective Randomized Control Trial of The Effectiveness of Alvimopan as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT04405037]Phase 458 participants (Anticipated)Interventional2020-08-01Recruiting
Measurement Of GI Myoelectric Activity In Patients At Risk For Or Who Have A Post-Operative Ileus (POI) - Monitoring/ Recording GI Myoelectric Activity For Early Detection of A POI[NCT02673671]150 participants (Anticipated)Observational2016-02-29Recruiting
A Prospective Evaluation of an Anesthesia Protocol to Reduce Post-operative and Post-discharge Nausea and Vomiting in a High Risk Orthognathic Surgery Population[NCT01592708]233 participants (Actual)Interventional2012-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hospital Length of Stay

Defined as the number of days between hospital admission and discharge (NCT02861131)
Timeframe: Length of hospitalization, an average of 1 week

Interventiondays (Mean)
Sugammadex4.0
Neostigmine4.5

Number of Participants Diagnosed With a National Surgical Quality Improvement Program (NSQIP) Defined Respiratory Complication

pneumonia, unplanned re-intubation for any reason other than a return trip to the operating room, and ventilator times greater than 48 hours - excluding operating room time (NCT02861131)
Timeframe: Length of hospitalization, an average of 1 week

InterventionParticipants (Count of Participants)
Sugammadex4
Neostigmine2

Number of Participants With a Postoperative Pulmonary Complication

A composite outcome which includes any of the following: postoperative pneumonia, aspiration pneumonitis, atelectasis, pneumothorax, desaturation/hypoxemia, upper airway obstruction, or acute respiratory insufficiency (NCT02861131)
Timeframe: Length of hospitalization, an average of 1 week

InterventionParticipants (Count of Participants)
Sugammadex33
Neostigmine40

Number of Participants With Hospital Readmission Within 30 Days

The proportion of patients that require hospital readmission for any cause within 30 days of hospital discharge (NCT02861131)
Timeframe: Length of hospitalization plus 30 days post-discharge

InterventionParticipants (Count of Participants)
Sugammadex5
Neostigmine15

Number of Participants With Residual Neuromuscular Blockade in the PACU

Residual neuromuscular blockade will be defined as a train-of-four ratio < 0.9 taken within 5 minutes of subject arrival in the PACU (NCT02861131)
Timeframe: 1 day

InterventionParticipants (Count of Participants)
Sugammadex9
Neostigmine46

PACU Phase 1 Recovery Time

Defined as duration of time required to attain pain control and stable respiratory, haemodynamic, and neurological status (NCT02861131)
Timeframe: 1 day

Interventionminutes (Mean)
Sugammadex97.3
Neostigmine110.0

Recovery Time From Neuromuscular Blockade

We measured recovery time ffrom the injection of neostigmine or sugammadex to TOF ratio 0.9 (NCT02330172)
Timeframe: from the injection of neostigmine or sugammadex up to 30 minutes

Interventionminute (Mean)
Rocuronium 0.45 - Neostigmine9.9
Rocuronium 0.9 - Sugammadex2.1

Laryngoscopic Score

"Definitions for evaluation of Laryngoscopycondition.~: Easy = jaw relaxed, no resistance to blade insertion, fair = jaw not fully relaxed, slight resistance to blade insertion, difficult = poor jaw relaxation, active resistance of the patient to laryngoscopy.~Variables Excellent Good Poor" (NCT02330172)
Timeframe: At the beginning of surgery, the surgeon rated the laryngoscopy condition

,
InterventionParticipants (Count of Participants)
DifficultFairEasy
Rocuronium 0.45 - Neostigmine1119
Rocuronium 0.9 - Sugammadex0019

Number of Patients Who Experience Postoperative Nausea and Vomiting, Post-operative Pain, and Post-operative Complications

(NCT02860507)
Timeframe: through discharge from hospital, average of 72 hours

InterventionParticipants (Count of Participants)
Neostigmine + Glycopyrrolate8
Sugammadex10

Operating Room (OR) Turnover Time When Using Sugammadex Instead of Combination of Neostigmine and Glycopyrrolate.

(NCT02860507)
Timeframe: through start of next surgery, average of 2 hours

InterventionMinutes (Mean)
Neostigmine + Glycopyrrolate49.7
Sugammadex49.45

Number of Participants Requiring Flexible Fiberoptic Bronchoscopy

The number of participants requiring flexible fiberoptic bronchoscopy during double-lumen tube intubation for a single lung ventilation. (NCT03690284)
Timeframe: Intraoperative, within the time the double lumen was in the trachea

InterventionParticipants (Count of Participants)
Conventional Double Lumen Tube25
VivaSight Double Lumen Tube7

Number of Participants With Malposition

The number of participants with malposition of double lumen tube for a single lung intubation (NCT03690284)
Timeframe: Intraoperative, within the time the double lumen was in the trachea

InterventionParticipants (Count of Participants)
Conventional Double Lumen Tube12
VivaSight Double Lumen Tube4

The Intubation Time

The time required to place double lumen endotracheal tube for a single lung intubation (NCT03690284)
Timeframe: Intraoperative, time to successfully intubate patient.

Interventionseconds (Median)
Conventional Double Lumen Tube156
VivaSight Double Lumen Tube54

Atelectasis Area on Chest CT

Atelectasis on Chest CT The lung area was delineated manually. To calculate atelectasis, a region of interest was laid out that encircled the dense part of the lung, excluding large vessels. For further analysis, the lung was divided into four categories: areas with densities ranging from -1000 to -900 Hounsfield units (HU) were classified as over-aerated, from -900 to -500 HU as normally aerated, from -500 to -100 HU as poorly aerated, and from -100 to +100 HU as non-aerated (atelectasis). The proportion of non-aerated lung tissue (-100 to +100 HU) was calculated by dividing the area of the region of interest with the whole lungs. (NCT03503565)
Timeframe: 1 day after the end of surgery

Interventionpercentage of atelectasis volume (Median)
Moderate Block Group1.32
Deep Block Group1.41

Additional Rescue Doses Per Hour Ratio.

Additional Rescue Doses Per Hour Ratio is the number per hour of addition of rescue dose administrated with 10% of initial NMBAs dose. The formula is {(Addition number + 1 / Anesthetic time) x 60}. (NCT02495038)
Timeframe: Intraoperative, an average of 3 hours.

Interventionratio (Mean)
Intubating Dose, Group I1.43455
10% Reduction of Combination of Esmeron® and Nimbex®, Group S1.21014
20% Reduction of Combination of Esmeron® and Nimbex®, Group L0.82128

Anesthetic Time

Time from induction to recovery of anesthesia, asessed up to 3 hours. (NCT02495038)
Timeframe: Intraoperative, an average 4 hours.

InterventionMinute (Mean)
Intubating Dose, Group I163.0
10% Reduction of Combination of Esmeron® and Nimbex®, Group S159.9
20% Reduction of Combination of Esmeron® and Nimbex®, Group L161.4

Bispectral Index

"The BIS monitor provides a single dimensionless number, which ranges from 0 (equivalent to EEG silence) to 100. A BIS value between 40 and 60 indicates an appropriate level for general anesthesia, as recommended by the manufacturer.~Before induction of anesthesia, bispectral index was measured for baseline. And after injection of NMBAs, bispectral index was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.

InterventionBIS score (Mean)
Intubating Dose, Group I46.0
10% Reduction of Combination of Esmeron® and Nimbex®, Group S46.1
20% Reduction of Combination of Esmeron® and Nimbex®, Group L44.3

Body Temperature

"Before induction of anesthesia, body temperature was measured for baseline by oral temperature probe.~And after injection of NMBAs, non invasive blood pressure was measured at 10 min by esophageal temperature probe." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.

InterventionCelcius degree (Mean)
Intubating Dose, Group I36.3
10% Reduction of Combination of Esmeron® and Nimbex®, Group S36.3
20% Reduction of Combination of Esmeron® and Nimbex®, Group L36.3

Duration 25% of Neuromuscular Blocking Agents(NMBAs)

Time from administration of initial NMBAs to Train-of-four (TOF) ratio >25%, assessed up to 2 hours during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 1 hours

InterventionMinute (Mean)
Intubating Dose, Group I51.3
10% Reduction of Combination of Esmeron® and Nimbex®, Group S47.9
20% Reduction of Combination of Esmeron® and Nimbex®, Group L39.4

Onset of Neuromuscular Blocking Agents(NMBAs)

Time from administration of initial NMBAs to Train-of-four (TOF) ratio=0, assessed up to 15 minutes during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 5 minutes

InterventionSecond (Mean)
Intubating Dose, Group I212.8
10% Reduction of Combination of Esmeron® and Nimbex®, Group S230.1
20% Reduction of Combination of Esmeron® and Nimbex®, Group L399.3

Operation Time

Time from skin incision to wound dressing assessed up to 8 hours. (NCT02495038)
Timeframe: Intraoperative, an average of 3 hours.

InterventionMinute (Mean)
Intubating Dose, Group I151.8
10% Reduction of Combination of Esmeron® and Nimbex®, Group S147.0
20% Reduction of Combination of Esmeron® and Nimbex®, Group L145.9

Peripheral Oxygen Saturation

"Before induction of anesthesia, peripheral oxygen saturation was measured for baseline.~And after injection of NMBAs, peripheral oxygen saturation was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.

InterventionPercentage (Mean)
Intubating Dose, Group I100
10% Reduction of Combination of Esmeron® and Nimbex®, Group S99.9
20% Reduction of Combination of Esmeron® and Nimbex®, Group L100

Recovery Index of Neuromuscular Blocking Agents(NMBAs)

Time from TOF ratio 25% to 75%, assessed up to 1 hour during general anesthesia. (NCT02495038)
Timeframe: Intraoperative, an average of 20 minutes

InterventionMinute (Mean)
Intubating Dose, Group I15.9
10% Reduction of Combination of Esmeron® and Nimbex®, Group S16.2
20% Reduction of Combination of Esmeron® and Nimbex®, Group L14.1

Non Invasive Blood Pressure,

"Before induction of anesthesia, non invasive blood pressure was measured for baseline.~And after injection of NMBAs, non invasive blood pressure was measured at 10 min." (NCT02495038)
Timeframe: Before and after induction of anesthesia, an average 10 min.

,,
InterventionmmHg (Mean)
Systolic pressureDiastolic pressure
10% Reduction of Combination of Esmeron® and Nimbex®, Group S128.376.7
20% Reduction of Combination of Esmeron® and Nimbex®, Group L128.474.8
Intubating Dose, Group I128.375.6

Complications

All adverse events (NCT02742181)
Timeframe: 30 days

InterventionNumber of AEs (Number)
Alvimopan Group4
Control Group6

Hospital Length of Stay

Date of surgery until discharge (NCT02742181)
Timeframe: up to 30 days

InterventionDays (Median)
Alvimopan Group9
Control Group8.5

Number of Readmissions

Any readmissions within 30 days of surgery (NCT02742181)
Timeframe: 30 days

InterventionNumber of readmissions (Number)
Alvimopan Group0
Control Group0

Number of Reoperations

Any reoperations within 30 days of surgery (NCT02742181)
Timeframe: 30 days

InterventionNumber of reoperations (Number)
Alvimopan Group0
Control Group0

Complications and Adverse Event

Number of patients with complication/adverse event. (NCT02218190)
Timeframe: 14 days or until hospital discharge, which ever occurs first

InterventionParticipants (Count of Participants)
Alvimopan0
Placebo - Sugar Pill0

Length of Hospital Stay

To determine the effect of alvimopan on overall length of hospital stay in patients undergoing PSF. (NCT02218190)
Timeframe: 14 days or until hospital discharge whichever occurs first

InterventionHours (Mean)
Alvimopan122.5
Placebo - Sugar Pill117.2

Recovery of Bowel Function

To determine the effect of alvimopan on the recovery of bowel function as determined by time to first bowel movement in patients undergoing posterior spinal fusion. The effect size calculated may guide a larger, multicenter randomized controlled study. Time was measured from wound closure to bowel movement. (NCT02218190)
Timeframe: 14 days or until hospital discharge whichever occurs first

InterventionHours (Mean)
Alvimopan43.2
Placebo - Sugar Pill34.0

Hospital Length of Stay

Anesthesia start time determined from anesthesia portion of the medical record. Time at which discharge order was placed will serve as time of discharge. (NCT01592708)
Timeframe: Anesthesia start time to placement of hospital discharge order - average 26 - 28 hours

Interventionhours (Median)
Intervention Cohort26.4
Comparison Cohort28.2

Post-discharge Nausea

To be assessed based on patient diary completed daily for 1 week following discharge to home from the hospital (NCT01592708)
Timeframe: 1 week from discharge from hospital

Interventionpercentage of subjects with PDN (Number)
Intervention Cohort72
Comparison Cohort60

Post-discharge Vomiting

(NCT01592708)
Timeframe: 1 week post discharge

Interventionpercentage of subjects with PDV (Number)
Intervention Cohort22
Comparison Cohort29

Post-operative Nausea

End of surgery time determined by anesthesia portion of the medical record. PONV to be assessed by review of surgeons' and nurses' notes in the medical record as well as through review of patient diaries. Vomiting constitutes a safety issue and, as such, associated adverse events will be noted. (NCT01592708)
Timeframe: End of surgery to discharge from hospital

Interventionpercentage of subjects with PON (Number)
Intervention Cohort24
Comparison Cohort70

Post-operative Vomiting

(NCT01592708)
Timeframe: End of surgery to discharge from hospital

Interventionpercentage of subjects with POV (Number)
Intervention Cohort11
Comparison Cohort28

Reviews

21 reviews available for neostigmine and Complication, Postoperative

ArticleYear
Sugammadex compared with neostigmine in reducing postoperative pulmonary complications in older patients: a meta-analysis.
    British journal of anaesthesia, 2022, Volume: 128, Issue:4

    Topics: Aged; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular Nondepol

2022
Sugammadex for reversing neuromuscular blockages after lung surgery: A systematic review and meta-analysis.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Humans; Length of Stay; Lung; Neostigmine; Neuromuscular Blockade; Postoperative Complications; Suga

2022
Superiority of sugammadex in preventing postoperative pulmonary complications.
    Chinese medical journal, 2023, Jul-05, Volume: 136, Issue:13

    Topics: Humans; Neostigmine; Neuromuscular Blockade; Pneumonia; Postoperative Complications; Respiratory Ins

2023
Reversal of neuromuscular block with sugammadex compared with neostigmine and postoperative pulmonary complications in obese patients: meta-analysis and trial sequential analysis.
    British journal of anaesthesia, 2023, Volume: 130, Issue:6

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Postoperative Complications;

2023
Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis.
    BMC anesthesiology, 2023, 04-20, Volume: 23, Issue:1

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular Blocking Agent

2023
Sugammadex Is Associated With Reduced Pulmonary Complications in Patients With Respiratory Dysfunction.
    The Journal of surgical research, 2023, Volume: 290

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Pleural Effusion; Postoperat

2023
Sugammadex Reduced the Incidence of Postoperative Pulmonary Complications in Susceptible Patients Identified by ARISCAT Risk Index: Systematic Review and Meta-analysis.
    Advances in therapy, 2023, Volume: 40, Issue:9

    Topics: Humans; Incidence; Neostigmine; Neuromuscular Blockade; Postoperative Complications; Pulmonary Atele

2023
The effects of acetylcholinesterase inhibitors on morbidity after general anesthesia and surgery.
    Neuropharmacology, 2020, 08-15, Volume: 173

    Topics: Anesthesia, General; Cardiovascular System; Cholinesterase Inhibitors; General Surgery; Humans; Morb

2020
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
[Residual neuromuscular blockade].
    Der Anaesthesist, 2017, Volume: 66, Issue:6

    Topics: Anesthesia Recovery Period; Delayed Emergence from Anesthesia; gamma-Cyclodextrins; Humans; Incidenc

2017
Postoperative complications with neuromuscular blocking drugs and/or reversal agents in obstructive sleep apnea patients: a systematic review.
    BMC anesthesiology, 2018, 07-19, Volume: 18, Issue:1

    Topics: Humans; Neostigmine; Neuromuscular Blocking Agents; Parasympathomimetics; Postoperative Complication

2018
Systematic scoping review of enhanced recovery protocol recommendations targeting return of gastrointestinal function after colorectal surgery.
    ANZ journal of surgery, 2020, Volume: 90, Issue:1-2

    Topics: Bisacodyl; Chewing Gum; Colonic Diseases; Humans; Ileus; Lactulose; Neostigmine; Piperidines; Postop

2020
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Residual paralysis: a real problem or did we invent a new disease?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:7

    Topics: Anesthesia Recovery Period; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Neostigmine; Neu

2013
Management of neuromuscular blockade in ambulatory patients.
    Current opinion in anaesthesiology, 2014, Volume: 27, Issue:6

    Topics: Ambulatory Surgical Procedures; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blocka

2014
[Muscle relaxants in ambulatory anesthesia].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:7

    Topics: Ambulatory Surgical Procedures; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; Intubation,

2008
Pharmacological management of postoperative ileus.
    Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal;

2009
[Indications and clinical use of sugammadex].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28 Suppl 2

    Topics: Algorithms; Androstanols; Anesthesia Recovery Period; Clinical Trials, Phase III as Topic; Contraind

2009
[Sugammadex: something new to improve patient safety or simply a gadget?].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28 Suppl 2

    Topics: Androstanols; Anesthesia Recovery Period; Atracurium; Cost-Benefit Analysis; Drug Approval; Electrod

2009
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Postoperative ileus: etiologies and interventions.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2003, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Decompression, Surgical; Early Ambulation; Gastrointestinal

2003
Anaesthesia and bowel surgery.
    British journal of anaesthesia, 1984, Volume: 56, Issue:1

    Topics: Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthetics; Animals; Carbon Dioxide; Gastro

1984
Anaesthesia for bowel surgery.
    Annales chirurgiae et gynaecologiae, 1984, Volume: 73, Issue:3

    Topics: Analgesia; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, General; Anesthetics; Carbon Diox

1984
Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review.
    British journal of anaesthesia, 1999, Volume: 82, Issue:3

    Topics: Cholinesterase Inhibitors; Humans; Muscle Weakness; Neostigmine; Neuromuscular Blocking Agents; Post

1999
Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review.
    British journal of anaesthesia, 1999, Volume: 82, Issue:3

    Topics: Cholinesterase Inhibitors; Humans; Muscle Weakness; Neostigmine; Neuromuscular Blocking Agents; Post

1999
Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review.
    British journal of anaesthesia, 1999, Volume: 82, Issue:3

    Topics: Cholinesterase Inhibitors; Humans; Muscle Weakness; Neostigmine; Neuromuscular Blocking Agents; Post

1999
Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review.
    British journal of anaesthesia, 1999, Volume: 82, Issue:3

    Topics: Cholinesterase Inhibitors; Humans; Muscle Weakness; Neostigmine; Neuromuscular Blocking Agents; Post

1999

Trials

32 trials available for neostigmine and Complication, Postoperative

ArticleYear
Comparison of the effects of neostigmine and sugammadex on postoperative residual curarization and postoperative pulmonary complications by means of diaphragm and lung ultrasonography: a study protocol for prospective double-blind randomized controlled tr
    Trials, 2022, May-07, Volume: 23, Issue:1

    Topics: Aged; Delayed Emergence from Anesthesia; Diaphragm; Double-Blind Method; Humans; Lung; Neostigmine;

2022
Sugammadex Versus Neostigmine for Neuromuscular Block Reversal and Postoperative Pulmonary Complications in Patients Undergoing Resection of Lung Cancer.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:9

    Topics: Adult; Atropine Derivatives; Cholinesterase Inhibitors; Humans; Lung; Lung Neoplasms; Neostigmine; N

2022
The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial.
    BMC anesthesiology, 2022, 08-22, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Colon; Delirium; Double-Blind Method; Humans; Middle Aged

2022
An educational intervention to reduce the incidence of postoperative residual curarisation: a cluster randomised crossover trial in patients undergoing general anaesthesia.
    British journal of anaesthesia, 2023, Volume: 131, Issue:3

    Topics: Anesthesia, General; Cross-Over Studies; Delayed Emergence from Anesthesia; Humans; Neostigmine; Neu

2023
Does sugammadex decrease the severity of agitation and complications in pediatric patients undergoing adenotonsillectomy?
    Saudi medical journal, 2019, Volume: 40, Issue:9

    Topics: Adenoidectomy; Adolescent; Anesthesia, General; Atropine; Child; Child, Preschool; Cough; Double-Bli

2019
Randomised controlled trial of sugammadex or neostigmine for reversal of neuromuscular block on the incidence of pulmonary complications in older adults undergoing prolonged surgery.
    British journal of anaesthesia, 2020, Volume: 124, Issue:5

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Delayed Emergence from Anesthesia; Double-Blind

2020
The effects of neostigmine on postoperative cognitive function and inflammatory factors in elderly patients - a randomized trial.
    BMC geriatrics, 2020, 10-06, Volume: 20, Issue:1

    Topics: Aged; Cholinesterase Inhibitors; Cognition; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscul

2020
Reversal of residual neuromuscular block with neostigmine or sugammadex and postoperative pulmonary complications: a prospective, randomised, double-blind trial in high-risk older patients.
    British journal of anaesthesia, 2021, Volume: 127, Issue:2

    Topics: Aged; Aged, 80 and over; Australia; Cholinesterase Inhibitors; Double-Blind Method; Female; Geriatri

2021
Comparison of reversal with neostigmine of low-dose rocuronium vs. reversal with sugammadex of high-dose rocuronium for a short procedure.
    Anaesthesia, 2017, Volume: 72, Issue:10

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Attitude of Health Personnel; Dose-Res

2017
Effect of sugammadex versus neostigmine/atropine combination on postoperative cognitive dysfunction after elective surgery.
    Anaesthesia and intensive care, 2017, Volume: 45, Issue:5

    Topics: Adult; Atropine; Cognitive Dysfunction; Double-Blind Method; Elective Surgical Procedures; Female; g

2017
Effects of neuromuscular block reversal with sugammadex versus neostigmine on postoperative respiratory outcomes after major abdominal surgery: a randomized-controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2019, Volume: 66, Issue:11

    Topics: Abdomen; Aged; Female; Humans; Male; Middle Aged; Neostigmine; Neuromuscular Blockade; Postoperative

2019
A comparison of sugammadex and neostigmine for reversal of rocuronium-induced neuromuscular blockade in children.
    Acta anaesthesiologica Scandinavica, 2017, Volume: 61, Issue:4

    Topics: Abdomen; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Atropine; Child; Child, Pres

2017
[Clinical observation on electroacupuncture combined with acupoint injection for treatment of early postoperative inflammatory intestinal obstruction].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2010, Volume: 30, Issue:1

    Topics: Acupuncture Points; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Electroacupuncture; F

2010
Antagonism of cisatracurium and rocuronium block at a tactile train-of-four count of 2: should quantitative assessment of neuromuscular function be mandatory?
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Atracurium; Cholinesterase Inhibi

2004
Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Intravenous; Anest

2005
[Treatment of intestinal atony following gynecologic operations. Study on the effectiveness and tolerance of ceruletide].
    Fortschritte der Medizin, 1984, Jul-26, Volume: 102, Issue:27-28

    Topics: Blood Pressure; Ceruletide; Clinical Trials as Topic; Constipation; Defecation; Female; Gastrointest

1984
[Drug treatment of postoperative intestinal atony].
    Fortschritte der Medizin, 1981, Jan-15, Volume: 99, Issue:1-2

    Topics: Adult; Aged; Ceruletide; Dihydroergotamine; Female; Gastrointestinal Diseases; Gastrointestinal Moti

1981
Perioperative train-of-four monitoring and residual curarization.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:8

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholinesterase

1995
Effect of antagonism of mivacurium-induced neuromuscular block on postoperative emesis in children.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Anesthesia Recovery Period; Atropine; Child; Double-Blind Method; Edrophonium; Glycopyrrolate; Human

1995
Effect of antagonizing residual neuromuscular block by neostigmine and atropine on postoperative vomiting.
    British journal of anaesthesia, 1994, Volume: 72, Issue:6

    Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, General; Atropine; Female; Huma

1994
Comparison of the combined effects of atropine and neostigmine with atropine and edrophonium on the occurrence of postoperative nausea and vomiting.
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1993, Volume: 31, Issue:2

    Topics: Adult; Atropine; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Edrophoniu

1993
[A double-blind study of neostigmine versus placebo in paralytic ileus as a result of surgical interventions].
    Minerva chirurgica, 1994, Volume: 49, Issue:5

    Topics: Administration, Intranasal; Adult; Aged; Analysis of Variance; Cholecystectomy; Double-Blind Method;

1994
Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:6

    Topics: Adult; Aged; Anesthesia, General; Double-Blind Method; Female; Humans; Hysterectomy; Isoquinolines;

1997
The efficacy of intrathecal neostigmine, intrathecal morphine, and their combination for post-cesarean section analgesia.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Female; Hu

1998
Glycopyrrolate methobromide: 2. comparison with atropine sulphate in anaesthesia.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Atropine; Blood Pressure; Bradycardia; Female; Glycopyrrolate; Humans; Inje

1975
Comparison of the combined effects of atropine and neostigmine with atropine and edrophonium on the lower oesophageal sphincter.
    Anaesthesia, 1991, Volume: 46, Issue:8

    Topics: Adult; Anesthesia, General; Atropine; Edrophonium; Esophagogastric Junction; Female; Gastroesophagea

1991
Influence of neostigmine on postoperative vomiting.
    British journal of anaesthesia, 1988, Volume: 61, Issue:4

    Topics: Aged; Atropine; Hip Prosthesis; Humans; Knee Prosthesis; Nausea; Neostigmine; Postoperative Complica

1988
Neostigmine in postoperative intestinal paralysis. A double-blind, clinical, controlled trial.
    Diseases of the colon and rectum, 1988, Volume: 31, Issue:5

    Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Intestinal Pseudo-Obstruction; Neostigmine; P

1988
Ceruletide and neostigmine in postoperative intestinal paralysis. A double-blind clinical controlled trial.
    Diseases of the colon and rectum, 1986, Volume: 29, Issue:11

    Topics: Adolescent; Adult; Aged; Ceruletide; Clinical Trials as Topic; Double-Blind Method; Humans; Intestin

1986
[Therapy of prolonged postoperative intestinal atony following interventions on the aorto-iliac circulation. Results of a prospective randomized study with ceruletide lyophilysate versus neostigmine].
    Fortschritte der Medizin, 1985, Apr-25, Volume: 103, Issue:16

    Topics: Aorta, Abdominal; Blood Vessel Prosthesis; Ceruletide; Clinical Trials as Topic; Constipation; Gastr

1985
A clinical study of pancuronium, a new muscular relaxant for abdominal surgery.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Abdomen; Adolescent; Adult; Age Factors; Aged; Androstanes; Anesthesia; Atropine; Body Weight; Clini

1972
Treatment of paralytic ileus with adrenergic neuronal blocking drugs.
    Surgery, 1971, Volume: 69, Issue:4

    Topics: Clinical Trials as Topic; Guanidines; Humans; Intestinal Obstruction; Neostigmine; Placebos; Postope

1971

Other Studies

120 other studies available for neostigmine and Complication, Postoperative

ArticleYear
Association of Sugammadex or Neostigmine With Major Postoperative Pulmonary Complications in Children.
    Anesthesia and analgesia, 2022, 11-01, Volume: 135, Issue:5

    Topics: Adult; Child; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Postoperative

2022
Identifying high dose neostigmine as a risk factor for post-operative respiratory complications: a case-control study.
    Anaesthesiology intensive therapy, 2021, Volume: 53, Issue:4

    Topics: Acetylcholinesterase; Case-Control Studies; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromus

2021
Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:12

    Topics: Anesthesia; Glycopyrrolate; Humans; Iatrogenic Disease; Muscles; Neostigmine; Neuromuscular Blockade

2022
Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study.
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Cholinesterase Inhibitors; Cohort Studies; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscula

2023
Influence of Sugammadex in Decreasing Postoperative Pulmonary Complications in Thoracic Surgery, is There Evidence?
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:9

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular Nondepolarizin

2022
Optimizing Reversal of Neuromuscular Block in Older Adults: Sugammadex or Neostigmine.
    Drugs & aging, 2022, Volume: 39, Issue:10

    Topics: Acetylcholine; Acetylcholinesterase; Aged; Cholinesterase Inhibitors; gamma-Cyclodextrins; Humans; N

2022
Effect of neuromuscular reversal with neostigmine/glycopyrrolate versus sugammadex on postoperative ileus following colorectal surgery.
    Techniques in coloproctology, 2023, Volume: 27, Issue:3

    Topics: Acetylcholinesterase; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Glycopyrrolate; Hu

2023
How robust are the STRONGER and STIL-STRONGER studies?
    British journal of anaesthesia, 2023, Volume: 130, Issue:1

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular Blocking Agent

2023
The effects of sugammadex vs. neostigmine on postoperative respiratory complications and advanced healthcare utilisation: a multicentre retrospective cohort study.
    Anaesthesia, 2023, Volume: 78, Issue:3

    Topics: Adult; Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Patient Acceptance of

2023
Sugammadex and neostigmine: when better may not be best.
    Anaesthesia, 2023, Volume: 78, Issue:5

    Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Postoperative Complications;

2023
Comparison effects of two muscle relaxant strategies on postoperative pulmonary complications in transapical transcatheter aortic valve implantation: a propensity score-matched analysis.
    Journal of cardiothoracic surgery, 2023, Feb-01, Volume: 18, Issue:1

    Topics: Adult; Humans; Muscles; Neostigmine; Postoperative Complications; Propensity Score; Rocuronium; Suga

2023
The efficacy and results of medical treatment in postoperative ileus.
    Nigerian journal of clinical practice, 2023, Volume: 26, Issue:4

    Topics: Diatrizoate Meglumine; Humans; Ileus; Intestinal Pseudo-Obstruction; Neostigmine; Postoperative Comp

2023
Usefulness of intra-operative neuromuscular blockade monitoring and reversal agents for postoperative residual neuromuscular blockade: a retrospective observational study.
    BMC anesthesiology, 2019, 08-07, Volume: 19, Issue:1

    Topics: Cholinesterase Inhibitors; Delayed Emergence from Anesthesia; Female; Humans; Male; Middle Aged; Neo

2019
Case report series of a novel application of neostigmine to successfully relieve refractory ileus status post-pediatric orthotopic liver transplantation.
    Pediatric transplantation, 2019, Volume: 23, Issue:7

    Topics: Child; Child, Preschool; Cholinesterase Inhibitors; Humans; Ileus; Infant; Liver Transplantation; Ma

2019
Effects of high neuromuscular blocking agent dose on post-operative respiratory complications in infants and children.
    Acta anaesthesiologica Scandinavica, 2020, Volume: 64, Issue:2

    Topics: Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Neostigmine; Neuromuscular B

2020
Association of neuromuscular reversal by sugammadex and neostigmine with 90-day mortality after non-cardiac surgery.
    BMC anesthesiology, 2020, 02-20, Volume: 20, Issue:1

    Topics: Cholinesterase Inhibitors; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neo

2020
Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis.
    Anesthesiology, 2020, Volume: 132, Issue:6

    Topics: Cholinesterase Inhibitors; Cohort Studies; Female; Humans; Male; Middle Aged; Neostigmine; Neuromusc

2020
Sugammadex and Postoperative Pulmonary Complications: Is Stronger Evidence Required?
    Anesthesiology, 2020, Volume: 132, Issue:6

    Topics: Cohort Studies; gamma-Cyclodextrins; Humans; Neostigmine; Neuromuscular Blockade; Postoperative Comp

2020
Comparison of the effects of sugammadex and neostigmine on hospital stay in robot-assisted laparoscopic prostatectomy: a retrospective study.
    BMC anesthesiology, 2020, 07-21, Volume: 20, Issue:1

    Topics: Aged; Cohort Studies; Humans; Laparoscopy; Length of Stay; Male; Middle Aged; Neostigmine; Neuromusc

2020
The "True" Risk of Postoperative Pulmonary Complications and the Socratic Paradox: "I Know that I Know Nothing".
    Anesthesiology, 2021, 06-01, Volume: 134, Issue:6

    Topics: Humans; Neostigmine; Postoperative Complications; Registries; Retrospective Studies; Sugammadex

2021
The effect of bariatric anaesthesia on postoperative pulmonary functions.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Bariatric Surgery; Bl

2017
Incidence of complications in the post-anesthesia care unit and associated healthcare utilization in patients undergoing non-cardiac surgery requiring neuromuscular blockade 2005-2013: A single center study.
    Journal of clinical anesthesia, 2017, Volume: 43

    Topics: Adult; Airway Extubation; Anesthesia Recovery Period; Cholinesterase Inhibitors; Elective Surgical P

2017
Postoperative pulmonary complications and reversal agents.
    British journal of anaesthesia, 2018, Volume: 120, Issue:3

    Topics: Delayed Emergence from Anesthesia; Humans; Lung; Neostigmine; Postoperative Complications; Sugammade

2018
Implementation of a new strategy to improve the peri-operative management of neuromuscular blockade and its effects on postoperative pulmonary complications.
    Anaesthesia, 2018, Volume: 73, Issue:9

    Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Hospital Costs; Hu

2018
Implementation of a new strategy to improve the peri-operative management of neuromuscular blockade and its effects on postoperative pulmonary complications.
    Anaesthesia, 2018, Volume: 73, Issue:9

    Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Hospital Costs; Hu

2018
Implementation of a new strategy to improve the peri-operative management of neuromuscular blockade and its effects on postoperative pulmonary complications.
    Anaesthesia, 2018, Volume: 73, Issue:9

    Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Hospital Costs; Hu

2018
Implementation of a new strategy to improve the peri-operative management of neuromuscular blockade and its effects on postoperative pulmonary complications.
    Anaesthesia, 2018, Volume: 73, Issue:9

    Topics: Adult; Aged; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Hospital Costs; Hu

2018
Management of rocuronium neuromuscular block using a protocol for qualitative monitoring and reversal with neostigmine.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Adult; Aged; Airway Extubation; Clinical Protocols; Cohort Studies; Female; Humans; Incidence; Male;

2018
Evaluation of Neuromuscular Blockade Reversal on Postoperative Mechanical Ventilation Time in a Cardiovascular Surgery Population.
    Journal of cardiothoracic and vascular anesthesia, 2019, Volume: 33, Issue:12

    Topics: Aged; Cardiovascular Diseases; Cardiovascular Surgical Procedures; Female; Follow-Up Studies; Humans

2019
Neostigmine reversal doesn't improve postoperative respiratory safety.
    BMJ (Clinical research ed.), 2013, Mar-19, Volume: 346

    Topics: Adult; Aged; Case-Control Studies; Female; Humans; Intraoperative Care; Male; Middle Aged; Neostigmi

2013
Acetylcholinesterase inhibitors reduce neuroinflammation and -degeneration in the cortex and hippocampus of a surgery stress rat model.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cerebral Cortex; Cholinesterase Inhibitors; Drug Evaluation, Prec

2013
Reversal of rocuronium induced neuromuscular block with sugammadex or neostigmine: a large observational study.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Abdomen; Adult; Aged; Airway Extubation; Analgesics, Opioid; Androstanols; Anesthesia Recovery Perio

2013
Reversal of rocuronium induced neuromuscular block with sugammadex or neostigmine: a large observational study.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Abdomen; Adult; Aged; Airway Extubation; Analgesics, Opioid; Androstanols; Anesthesia Recovery Perio

2013
Reversal of rocuronium induced neuromuscular block with sugammadex or neostigmine: a large observational study.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Abdomen; Adult; Aged; Airway Extubation; Analgesics, Opioid; Androstanols; Anesthesia Recovery Perio

2013
Reversal of rocuronium induced neuromuscular block with sugammadex or neostigmine: a large observational study.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Abdomen; Adult; Aged; Airway Extubation; Analgesics, Opioid; Androstanols; Anesthesia Recovery Perio

2013
"Neostigmine-resistant curarization".
    Middle East journal of anaesthesiology, 2013, Volume: 22, Issue:2

    Topics: Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Neostigmine; Neuromuscular Bloc

2013
Retrospective investigation of postoperative outcome after reversal of residual neuromuscular blockade: sugammadex, neostigmine or no reversal.
    European journal of anaesthesiology, 2014, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Female; gamma-Cyclodextrins; Humans; Lung Disease

2014
Postoperative respiratory outcomes in laparoscopic bariatric surgery: comparison of a prospective group of patients whose neuromuscular blockade was reverted with sugammadex and a historical one reverted with neostigmine.
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:10

    Topics: Adult; Aged; Bariatric Surgery; Cholinesterase Inhibitors; Female; gamma-Cyclodextrins; Humans; Lapa

2014
Neostigmine vs. sugammadex: observational cohort study comparing the quality of recovery using the Postoperative Quality Recovery Scale.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:9

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Cholinesterase Inhibitors; Cohort Studies; F

2014
Neostigmine and pulmonary oedema.
    BMJ case reports, 2014, Sep-08, Volume: 2014

    Topics: Anesthesia, General; Cholinesterase Inhibitors; Glycopyrrolate; Humans; Infant; Neostigmine; Postope

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
    Anesthesiology, 2014, Volume: 121, Issue:5

    Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged;

2014
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.
    Anesthesiology, 2015, Volume: 122, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dose-Response

2015
Neostigmine induced anaphylaxis in the wake of surgery.
    Anaesthesia, critical care & pain medicine, 2015, Volume: 34, Issue:2

    Topics: Aged; Anaphylaxis; Cholinesterase Inhibitors; Female; Humans; Neostigmine; Postoperative Complicatio

2015
Incidence of postoperative residual neuromuscular blockade after general anesthesia: a prospective, multicenter, anesthetist-blind, observational study.
    Current medical research and opinion, 2016, Volume: 32, Issue:1

    Topics: Abdomen; Adult; Aged; Anesthesia, General; Delayed Emergence from Anesthesia; Female; Humans; Incide

2016
Neostigmine: You Can't Have It Both Ways.
    Anesthesiology, 2015, Volume: 123, Issue:1

    Topics: Female; Humans; Male; Neostigmine; Neuromuscular Nondepolarizing Agents; Parasympathomimetics; Posto

2015
In Reply.
    Anesthesiology, 2015, Volume: 123, Issue:1

    Topics: Female; Humans; Male; Neostigmine; Neuromuscular Nondepolarizing Agents; Parasympathomimetics; Posto

2015
Neostigmine: Timing and dosing in 2016.
    Anaesthesia, critical care & pain medicine, 2016, Volume: 35, Issue:4

    Topics: Anesthesia, General; Cholinesterase Inhibitors; Humans; Neostigmine; Paralysis; Postoperative Compli

2016
Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia.
    Anesthesiology, 2016, Volume: 125, Issue:4

    Topics: Causality; Cholinesterase Inhibitors; Databases, Factual; Female; Humans; Incidence; Male; Middle Ag

2016
Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia.
    Anesthesiology, 2016, Volume: 125, Issue:4

    Topics: Causality; Cholinesterase Inhibitors; Databases, Factual; Female; Humans; Incidence; Male; Middle Ag

2016
Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia.
    Anesthesiology, 2016, Volume: 125, Issue:4

    Topics: Causality; Cholinesterase Inhibitors; Databases, Factual; Female; Humans; Incidence; Male; Middle Ag

2016
Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia.
    Anesthesiology, 2016, Volume: 125, Issue:4

    Topics: Causality; Cholinesterase Inhibitors; Databases, Factual; Female; Humans; Incidence; Male; Middle Ag

2016
The O-Sign: early recognition of O-shaped abdominal distension avoids drastic surgical intervention in Ogilvie Syndrome after caesarean section.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 204

    Topics: Adult; Cesarean Section; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Colonoscopy; Drainag

2016
The Potentially Fatal Ogilvie's Syndrome in Lateral Transpsoas Access Surgery: A Multi-Institutional Experience with 2930 Patients.
    World neurosurgery, 2017, Volume: 99

    Topics: Aged; Aged, 80 and over; Cecum; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Female; Human

2017
Intermediate-Acting Nondepolarizing Neuromuscular Blocking Agents and Risk of Postoperative 30-Day Morbidity and Mortality, and Long-term Survival.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:5

    Topics: Adult; Aged; Anesthesia Recovery Period; Cholinesterase Inhibitors; Female; Humans; Male; Middle Age

2017
Neostigmine in arthritis; a case with toxic reaction.
    Quarterly bulletin. Northwestern University (Evanston, Ill.). Medical School, 1948, Volume: 22, Issue:2

    Topics: Arthritis; Humans; Neostigmine; Postoperative Complications

1948
[On "Ventricular fibrillation in a patient with type I Brugada syndrome"].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:8

    Topics: Brugada Syndrome; Contraindications; Defibrillators; Electric Countershock; Humans; Hypokalemia; Mal

2008
Recurarisation in a surgical ward.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:6

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, General; Anes

2008
Anesthesia and myotonic dystrophy type 2: a case series.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:3

    Topics: Adult; Anesthesia; Anesthetics, Inhalation; Cholinesterase Inhibitors; Female; Humans; Intraoperativ

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
Emergence agitation in adults: risk factors in 2,000 patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr

2010
The effect of neostigmine on postoperative ileus and the healing of colon anastomoses.
    Bratislavske lekarske listy, 2011, Volume: 112, Issue:6

    Topics: Anastomosis, Surgical; Animals; Body Weight; Cholinesterase Inhibitors; Colon; Dietary Proteins; Fem

2011
Neostigmine and FESS.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2011, Volume: 36, Issue:3

    Topics: Chronic Disease; Endoscopy; Female; Follow-Up Studies; Humans; Middle Aged; Neostigmine; Otorhinolar

2011
Neostigmine in the treatment of refractory constipation in critically ill children.
    Journal of pediatric gastroenterology and nutrition, 2011, Volume: 53, Issue:2

    Topics: Adolescent; Cathartics; Child; Child, Preschool; Cholinesterase Inhibitors; Constipation; Drug Resis

2011
Re: Neostigmine and Functional Endoscopic Sinus Surgery - ocular side-effects of other general anaesthetic agents.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2011, Volume: 36, Issue:5

    Topics: Endoscopy; Female; Humans; Neostigmine; Otorhinolaryngologic Surgical Procedures; Parasympathomimeti

2011
[Likely injection of neosynephrine on the place of the prostigmine: an adverse effect!].
    Annales francaises d'anesthesie et de reanimation, 2012, Volume: 31, Issue:1

    Topics: Adult; Anesthesia, General; Blood Gas Analysis; Blood Pressure; Drug Labeling; Drug Packaging; Femal

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.
    BMJ (Clinical research ed.), 2012, Oct-15, Volume: 345

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cholinesterase Inhibitors; Fema

2012
A CASE OF SUXAMETHONIUM SENSITIVITY.
    The Medical journal of Australia, 1963, Aug-10, Volume: 2

    Topics: Anesthesia; Anesthesiology; Apnea; Atropine; Bis-Trimethylammonium Compounds; Butyrylcholinesterase;

1963
RESPIRATORY AND CARDIAC ARREST AFTER INTRAVENOUS ADMINISTRATION OF KANAMYCIN WITH REVERSAL OF TOXIC EFFECTS BY NEOSTIGMINE.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Abscess; Administration, Intravenous; Adolescent; Appendix; Drug Hypersensitivity; Escherichia coli

1963
PROLONGED PARESIS FOLLOWING GALLAMINE; A CASE REPORT.
    British journal of anaesthesia, 1963, Volume: 35

    Topics: Anuria; Apnea; Gallamine Triethiodide; Humans; Kidney; Kidneys, Artificial; Neostigmine; Paralysis;

1963
[OUR EXPERIENCES WITH GENERAL ANESTHESIA IN HEART SURGERY].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1963, Volume: 42

    Topics: Anesthesia; Anesthesia, General; Cardiac Surgical Procedures; Humans; Neostigmine; Postoperative Com

1963
A CASE OF POST-OPERATIVE APNOEA RESPONDING TO INTRAVENOUS SODIUM BICARBONATE INFUSION.
    The Medical journal of Australia, 1964, Apr-04, Volume: 1

    Topics: Acidosis; Apnea; Atropine; Bicarbonates; Bis-Trimethylammonium Compounds; Gallamine Triethiodide; Hu

1964
[RADIOLOGICAL STUDIES ON THE RESTORATION OF POSTOPERATIVE PARALYTIC ILEUS AND THE EFFECT OF VARIOUS DRUGS AND MANAGEMENT].
    Rinsho geka. Journal of clinical surgery, 1964, Volume: 19

    Topics: Atropine; Humans; Hypertonic Solutions; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Neost

1964
MANAGEMENT OF THE PATIENT WITH MYASTHENIA GRAVIS FOR THYMECTOMY.
    Canadian Anaesthetists' Society journal, 1964, Volume: 11

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesiology; Myasthenia Gravis; Neostigmine; Parasympathomime

1964
[A CONTRIBUTION TO THE TREATMENT OF INTESTINAL PARALYSIS IN CHILDHOOD].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1964, Volume: 35

    Topics: Acidosis; Humans; Hypoxia; Infant; Intestinal Obstruction; Intussusception; Neostigmine; Postoperati

1964
Postoperative delirium and Ogilvie's syndrome resolving with neostigmine.
    Journal of the American Geriatrics Society, 2006, Volume: 54, Issue:6

    Topics: Aged; Arthroplasty, Replacement, Knee; Cholinesterase Inhibitors; Colonic Pseudo-Obstruction; Deliri

2006
[Postoperative apnea after suxamethonium].
    Archiv fur Gynakologie, 1966, Volume: 203, Issue:3

    Topics: Adult; Apnea; Bis-Trimethylammonium Compounds; Blood Transfusion; Cholinesterases; Female; Humans; M

1966
An evoked phonointestinography.
    Wakayama medical reports, 1967, Volume: 11, Issue:4

    Topics: Electrodiagnosis; Humans; Intestinal Diseases; Laparotomy; Neostigmine; Postoperative Complications

1967
Recurarization with quinine administration after reversal from anaesthesia.
    Anaesthesia and intensive care, 1983, Volume: 11, Issue:3

    Topics: Atropine; Drug Interactions; Humans; Male; Middle Aged; Neostigmine; Nerve Block; Neuromuscular Junc

1983
[Anesthesia in dystrophia myotonica using the capnogram].
    Der Anaesthesist, 1984, Volume: 33, Issue:8

    Topics: Adolescent; Adult; Anesthesia; Carbon Dioxide; Female; Heart Function Tests; Humans; Male; Middle Ag

1984
Studies in intestinal healing VI. Effect of pharmacologically induced peristalsis on fresh intestinal anastomoses in dogs.
    Archives of surgery (Chicago, Ill. : 1960), 1980, Volume: 115, Issue:3

    Topics: Animals; Castor Oil; Colon; Dogs; Gastrointestinal Motility; Ileum; Intestines; Jejunum; Neostigmine

1980
Administration of depolarizing muscle relaxants after non-depolarizer reversal -- when is it safe?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, May-29, Volume: 61, Issue:22

    Topics: Aged; Anesthesia; Humans; Male; Neostigmine; Postoperative Complications; Time Factors

1982
Adrenergic and cholinergic contributions to decreased gastric emptying, small intestinal transit, and colonic transit in the postoperative ileus rat.
    The Journal of surgical research, 1980, Volume: 29, Issue:2

    Topics: Animals; Bethanechol Compounds; Colon; Disease Models, Animal; Gastric Emptying; Gastrointestinal Mo

1980
Does neostigmine cause nausea and vomiting?
    Anesthesia and analgesia, 1995, Volume: 80, Issue:4

    Topics: Humans; Nausea; Neostigmine; Postoperative Complications; Vomiting

1995
Neostigmine and postoperative nausea.
    British journal of anaesthesia, 1994, Volume: 73, Issue:5

    Topics: Fasting; Humans; Nausea; Neostigmine; Postoperative Complications

1994
Neostigmine and postoperative nausea.
    British journal of anaesthesia, 1994, Volume: 73, Issue:5

    Topics: Atropine; Humans; Nausea; Neostigmine; Postoperative Complications

1994
Postoperative recurrent paralysis in an infant after mivacurium infusion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:8

    Topics: Female; Humans; Infant; Infusions, Intravenous; Isoquinolines; Mivacurium; Muscle Contraction; Neost

1994
[Thirst is the most common minor complication in the immediate postoperative period].
    Revista espanola de anestesiologia y reanimacion, 1996, Volume: 43, Issue:2

    Topics: Adjuvants, Anesthesia; Adult; Aged; Atropine; Blood Loss, Surgical; Female; Humans; Incidence; Male;

1996
Reversal of neuromuscular blockade.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Female; Humans; Hysterectomy; Nausea; Neostigmine; Neuromuscular Blockade; Postoperative Complicatio

1998
Other ways to stimulate postoperative bowel function.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:2

    Topics: Humans; Intestinal Pseudo-Obstruction; Neostigmine; Postoperative Complications

1998
[Erroneous attitudes in the use of neuromuscular blocking agents].
    Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:2

    Topics: Anesthesia Recovery Period; Anesthesiology; Attitude of Health Personnel; Cholinesterase Inhibitors;

2002
[Postoperative ileus. Measurement of the changes in intragastric pressure immediately after abdominal operations (practical deductions)].
    Journal de chirurgie, 1975, Volume: 109, Issue:4

    Topics: Abdomen; Adrenergic beta-Antagonists; Gastrointestinal Motility; Humans; Intestinal Obstruction; Int

1975
Residual paralysis in the recovery period.
    Acta anaesthesiologica Belgica, 1979, Volume: 30 Suppl

    Topics: Humans; Neostigmine; Neuromuscular Blocking Agents; Neuromuscular Junction; Paralysis; Postoperative

1979
[Effect of dihydergot on the postoperative intestinal atonia. Experimental studies].
    Die Medizinische Welt, 1978, Dec-15, Volume: 29, Issue:50

    Topics: Animals; Dihydroergotamine; Female; Intestinal Obstruction; Male; Neostigmine; Postoperative Complic

1978
Glycopyrrolate and cardiac dysrhythmias in geriatric patients after reversal of neuromuscular blockade.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Cardiovascular Diseases; Cholinesterase Inhibitors; Glycopyrro

1979
[Transient and curable myasthenia appearing 3 years after lower right thymectomy].
    Le Poumon et le coeur, 1977, Volume: 33, Issue:2

    Topics: Female; Humans; Middle Aged; Myasthenia Gravis; Neostigmine; Postoperative Complications; Pyridostig

1977
Duodenoscopy and endoscopic pancreatography in patients with postive morphine prostigmine tests.
    American journal of surgery, 1977, Volume: 134, Issue:3

    Topics: Adolescent; Adult; Biliary Tract Diseases; Cholangiography; Cholecystectomy; Chronic Disease; Cicatr

1977
[Experimental studies of the effects of gastrin, neostigmine and prostaglandin on the motility of the trunculary vagotomized stomach].
    Langenbecks Archiv fur Chirurgie, 1976, Volume: Suppl

    Topics: Animals; Dogs; Gastrins; Gastrointestinal Motility; Neostigmine; Postoperative Complications; Prosta

1976
Tracheobronchial hypersecretion following neostigmine administration.
    Cleveland Clinic quarterly, 1975,Summer, Volume: 42, Issue:2

    Topics: Adult; Aged; Bronchi; Female; Humans; Male; Middle Aged; Neostigmine; Postoperative Complications; S

1975
Effects of some drugs on electrical activity of the gut in the postoperative period.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1976, Volume: 8, Issue:1

    Topics: Cholecystectomy; Cholecystokinin; Gastrointestinal Motility; Humans; Intestinal Obstruction; Jejunum

1976
Renal failure and postoperative respiratory failure: recurarization?
    British journal of anaesthesia, 1976, Volume: 48, Issue:3

    Topics: Adult; Anesthesia, General; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Neostigmine;

1976
Atrial fibrillation associated with neostigmine administration in three cows.
    Journal of the American Veterinary Medical Association, 1990, Jan-15, Volume: 196, Issue:2

    Topics: Animals; Atrial Fibrillation; Cattle; Cattle Diseases; Electrocardiography; Female; Intestinal Obstr

1990
Sensitivity to both vecuronium and neostigmine in a sero-negative myasthenic patient.
    British journal of anaesthesia, 1989, Volume: 63, Issue:4

    Topics: Adult; Apnea; Female; Humans; Myasthenia Gravis; Neostigmine; Postoperative Complications; Vecuroniu

1989
Therapy and clinical progress of cattle with dilatation and torsion of the caecum.
    The Veterinary record, 1989, Oct-21, Volume: 125, Issue:17

    Topics: Animals; Cathartics; Cattle; Cattle Diseases; Cecal Diseases; Cecum; Defecation; Dilatation, Patholo

1989
[Treatment of postoperatory ileus with several drugs].
    Revista espanola de las enfermedades del aparato digestivo, 1989, Volume: 76, Issue:2

    Topics: Animals; Drug Combinations; Intestinal Obstruction; Mepivacaine; Neostigmine; Phentolamine; Postoper

1989
Recurarisation after vecuronium in a patient with renal failure.
    Anaesthesia, 1987, Volume: 42, Issue:9

    Topics: Acidosis; Adult; Atropine; Female; Humans; Kidney Failure, Chronic; Neostigmine; Neuromuscular Junct

1987
Dehiscence of intestinal anastomoses and anaesthesia.
    The Italian journal of surgical sciences, 1988, Volume: 18, Issue:3

    Topics: Adult; Aged; Anastomosis, Surgical; Anesthesia, General; Colon; Female; Humans; Male; Middle Aged; M

1988
Recurarisation following a suxamethonium-alcuronium sequence in patients with atypical cholinesterase.
    Anaesthesia, 1988, Volume: 43, Issue:4

    Topics: Adult; Alcuronium; Cholinesterases; Female; Humans; Middle Aged; Neostigmine; Postoperative Complica

1988
Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.
    Anaesthesia, 1987, Volume: 42, Issue:12

    Topics: Aged; Atenolol; Bradycardia; Drug Interactions; Female; Humans; Hypotension; Neostigmine; Pancuroniu

1987
Colonic anastomotic disruption in myasthenia gravis. Report of two cases.
    Diseases of the colon and rectum, 1987, Volume: 30, Issue:10

    Topics: Adult; Aged; Anastomosis, Surgical; Colon; Glucagon; Humans; Male; Myasthenia Gravis; Neostigmine; P

1987
Therapeutic rounds: abnormally prolonged responses to neuromuscular blocking agents.
    Clinical therapeutics, 1986, Volume: 9, Issue:1

    Topics: Apnea; Drug Interactions; Humans; Male; Middle Aged; Neostigmine; Pancuronium; Postoperative Complic

1986
Antagonism of neuromuscular block in the elderly. A comparison of atropine and glycopyrronium in a mixture with neostigmine.
    Anaesthesia, 1985, Volume: 40, Issue:3

    Topics: Age Factors; Aged; Arrhythmias, Cardiac; Atropine; Female; Glycopyrrolate; Heart Rate; Humans; Male;

1985
Pancreas divisum. Detection and management.
    The American surgeon, 1985, Volume: 51, Issue:6

    Topics: Adult; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; Female; Follow-Up Studies;

1985
Is endoscopic sphincterotomy for disabling biliary-type pain after cholecystectomy effective?
    Gastrointestinal endoscopy, 1985, Volume: 31, Issue:6

    Topics: Anal Canal; Biliary Tract Diseases; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy

1985
Letter: Neostigmine after bowel surgery.
    Lancet (London, England), 1974, Sep-21, Volume: 2, Issue:7882

    Topics: Colon; Drug Antagonism; Humans; Muscle Relaxants, Central; Neostigmine; Postoperative Complications;

1974
Reversal of neuromuscular blockade by artificial diuresis: case report.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Inhalation; Atropine; Diuresis; Gallamine Triethiodide; Hu

1972
Prolonged paresis following the administration of gallamine triethiodide (Flaxedil) to a patient with acute pancreatitis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jun-16, Volume: 47, Issue:23

    Topics: Acute Disease; Acute Kidney Injury; Anesthesia, General; Atropine; Gallamine Triethiodide; Humans; M

1973
[Acute respiratory dishess syndrome due to high dosage of penicilline in a case of myasthenia gravis (author's transl)].
    Der Anaesthesist, 1973, Volume: 22, Issue:11

    Topics: Adult; Apnea; Atropine; Drug Hypersensitivity; Female; Humans; Myasthenia Gravis; Neostigmine; Penic

1973
Efficient anaesthesia with the EMO ether inhaler.
    Tropical doctor, 1974, Volume: 4, Issue:3

    Topics: Adult; Anesthesia, Inhalation; Child; Costs and Cost Analysis; Curare; Ethyl Ethers; Evaluation Stud

1974
Management of resistant ileus by the Neely-Catchpole regimen.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Mar-11, Volume: 46, Issue:11

    Topics: Aged; Chronic Disease; Depression, Chemical; Drug Resistance; Female; Guanethidine; Humans; Injectio

1972
Thymectomy for myasthenia gravis.
    Thorax, 1972, Volume: 27, Issue:5

    Topics: Activities of Daily Living; Adolescent; Adult; Age Factors; Aged; Bronchopneumonia; Child; Female; F

1972
Ileus and pseudo-obstruction.
    British medical journal, 1971, Jun-26, Volume: 2, Issue:5764

    Topics: Abdomen; Aged; Female; Gases; Gastrointestinal Motility; Guanethidine; Humans; Intestinal Obstructio

1971
[Experimental and clinical observation of postoperative chronic obstipation].
    Kobe Ika Daigaku kiyo, 1964, Volume: 26, Issue:4

    Topics: Abdomen; Adult; Animals; Chronic Disease; Colon; Constipation; Dogs; Electromyography; Gastrointesti

1964
[Development, prophylaxis and therapy of urinary TRACT infections following gynecological operations].
    Deutsche medizinische Wochenschrift (1946), 1967, Nov-24, Volume: 92, Issue:47

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Electric Stimulation Therapy; Female; Genital Disea

1967
Neostigmine and anastomotic disruption.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:8

    Topics: Colectomy; Gastrointestinal Motility; Humans; Intestinal Perforation; Neostigmine; Postoperative Com

1970
Ileus: the restoration of alimentary-tract motility by pharmacological means.
    The British journal of surgery, 1971, Volume: 58, Issue:1

    Topics: Aged; Bethanechol Compounds; Female; Gastrointestinal Motility; Guanethidine; Humans; Intestinal Obs

1971
The prevention of muscle pains associated with the use of suxamethonium.
    British journal of anaesthesia, 1967, Volume: 39, Issue:12

    Topics: Adult; Barbiturates; Bronchoscopy; Humans; Injections, Intramuscular; Injections, Intravenous; Male;

1967
Aortic valve replacement in the Wolff-Parkinson-White syndrome.
    British heart journal, 1968, Volume: 30, Issue:4

    Topics: Adult; Aortic Valve; Heart Valve Prosthesis; Humans; Male; Neostigmine; Postoperative Complications;

1968
Effect of neostigmine on integrity of ileorectal anastomoses.
    British medical journal, 1968, Sep-07, Volume: 3, Issue:5618

    Topics: Adolescent; Adult; Aged; Animals; Child; Colectomy; Colitis, Ulcerative; Humans; Ileum; Middle Aged;

1968
[Contribution on the problem of muscle pains after succinylcholine administration].
    Der Anaesthesist, 1968, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Child; Female; Germany, East; Halothane;

1968
Neostigmine resistant curarization associated with oliguria of acute onset.
    Israel journal of medical sciences, 1965, Volume: 1, Issue:4

    Topics: Acute Kidney Injury; Aged; Anuria; Female; Humans; Male; Middle Aged; Neostigmine; Postoperative Com

1965
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