Page last updated: 2024-10-31

neostigmine and Blood Pressure, Low

neostigmine has been researched along with Blood Pressure, Low in 20 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Research Excerpts

ExcerptRelevanceReference
"Spinal neostigmine causes analgesia in animals and humans and abolishes hypotension from spinal bupivacaine in rats."7.69Spinal neostigmine diminishes, but does not abolish, hypotension from spinal bupivacaine in sheep. ( Eisenach, JC; Rose, G; Tong, C; Xu, Z, 1996)
"To test whether neostigmine would alter clonidine-induced hypotension, nine chronically prepared sheep received intrathecal injections of saline or neostigmine (150, 300, 1,000 micrograms) followed in 15 min by 200 micrograms clonidine."7.68Neostigmine counteracts spinal clonidine-induced hypotension in sheep. ( Eisenach, JC; Tong, C; Williams, JS, 1993)
"Spinal neostigmine causes analgesia in animals and humans and abolishes hypotension from spinal bupivacaine in rats."3.69Spinal neostigmine diminishes, but does not abolish, hypotension from spinal bupivacaine in sheep. ( Eisenach, JC; Rose, G; Tong, C; Xu, Z, 1996)
"To test whether neostigmine would alter clonidine-induced hypotension, nine chronically prepared sheep received intrathecal injections of saline or neostigmine (150, 300, 1,000 micrograms) followed in 15 min by 200 micrograms clonidine."3.68Neostigmine counteracts spinal clonidine-induced hypotension in sheep. ( Eisenach, JC; Tong, C; Williams, JS, 1993)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199013 (65.00)18.7374
1990's4 (20.00)18.2507
2000's2 (10.00)29.6817
2010's0 (0.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Paredes, S1
Torres, VH1
Chaves-Cardona, H1
Matus, M1
Porter, S1
Renew, JR1
Mathis, KW1
Molina, PE1
Thomas, MC1
Erstad, BL1
GOERRE, J1
PANDEY, K1
KUMAR, S1
BADOLA, RP1
GREENWOOD, RJ1
TUTTLE, RS1
CONNOR, RS1
KREUL, W1
ORTH, OS1
ERDMANN, WD1
MERCKER, H1
ALTANA, G1
Baraka, A2
Goudas, LC1
Filos, KS1
Williams, JS1
Tong, C2
Eisenach, JC2
Rose, G1
Xu, Z1
Fedorov, VI1
Eldor, J1
Hoffman, B1
Davidson, JT1
Molchanova, GIa1
Voznesenskiĭ, BB1
Vetten, KB1
Lett, Z1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized Trial of Enteral Naloxone Versus a Traditional Bowel Regimen in Prevention of Constipation and Decreased Gastric Motility in Critically Ill Trauma Patients[NCT00799201]Phase 43 participants (Actual)Interventional2007-08-31Terminated (stopped due to Naloxone became unavailable due to manufacturing shortatges requiring the study to be terminated.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for neostigmine and Blood Pressure, Low

ArticleYear
Safety of enteral naloxone and i.v. neostigmine when used to relieve constipation.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jun-15, Volume: 60, Issue:12

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Colic;

2003
[Functional peculiarities of the cardiovascular system in healthy parturients on various days of the puerperium].
    Akusherstvo i ginekologiia, 1966, Volume: 42, Issue:9

    Topics: Adaptation, Physiological; Adult; Cardiovascular Physiological Phenomena; Cardiovascular System; Cho

1966

Other Studies

18 other studies available for neostigmine and Blood Pressure, Low

ArticleYear
An appraisal of neostigmine versus sugammadex for neuromuscular blockade reversal in patients with a prior heart transplant.
    Anaesthesiology intensive therapy, 2023, Volume: 55, Issue:1

    Topics: Anesthetics; Bradycardia; Heart Transplantation; Humans; Hypotension; Neostigmine; Neuromuscular Blo

2023
Central acetylcholinesterase inhibition improves hemodynamic counterregulation to severe blood loss in alcohol-intoxicated rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:2

    Topics: Alcoholic Intoxication; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Bl

2009
[Influencing hypotensive states with prostigmin resulting from ganglion block with ecolid in man].
    Helvetica medica acta, 1957, Volume: 24, Issue:4

    Topics: Autonomic Agents; Autonomic Nervous System; Chlorisondamine; Humans; Hypotension; Male; Neostigmine

1957
NEUROMUSCULAR BLOCKING AND HYPOTENSIVE ACTIONS OF STREPTOMYCIN, AND THEIR REVERSAL.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Autonomic Nerve Block; Calcium; Chloralose; Chlorides; Dogs; Hypotension; Neostigmine; Neuromuscular

1964
THE PROPER USE OF CAROTID SINUS STIMULATION.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Carotid Sinus; Diagnosis; Digitalis Glycosides; Drug Therapy;

1964
AN INTENSE HYPOTENSIVE RESPONSE EVOKED BY MEDULLARY STIMULATION IN THE PYRAMIDAL CAT.
    The American journal of physiology, 1965, Volume: 208

    Topics: Adrenal Medulla; Atropine; Cats; Electric Stimulation; Hexamethonium Compounds; Histology; Hypotensi

1965
Treatment of the hypotensive states of spinal analgesia with dilute neosynephrin solution.
    Anesthesiology, 1951, Volume: 12, Issue:4

    Topics: Analgesia; Anesthesia; Blood Pressure; Humans; Hypotension; Neostigmine

1951
[Hypotension caused by d-tubocurarine; antagonistic effect of prostigmine].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1952, Volume: 214, Issue:5

    Topics: Blood Pressure; Blood Pressure Determination; Curare; Hostility; Hypotension; Neostigmine; Tubocurar

1952
[Hypotensive effect of prostigmine: hemodynamic study in normotensive subjects].
    Folia cardiologica, 1949, Volume: 8, Issue:4

    Topics: Blood Pressure; Hemodynamics; Humans; Hypotension; Neostigmine

1949
A comparative study between diallylnortoxiferine and tubocurarine.
    British journal of anaesthesia, 1967, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Aged; Atropine; Blood Pressure; Humans; Hypotension; Middle Aged; Neostigmine; Ne

1967
Pretreatment with an intrathecal cholinergic pressor agent: is it necessary?
    Anesthesiology, 1994, Volume: 80, Issue:5

    Topics: Anesthesia, Spinal; Animals; Blood Pressure; Clonidine; Humans; Hypotension; Neostigmine; Premedicat

1994
Neostigmine counteracts spinal clonidine-induced hypotension in sheep.
    Anesthesiology, 1993, Volume: 78, Issue:2

    Topics: Animals; Clonidine; Female; Hypotension; Injections, Spinal; Neostigmine; Sheep

1993
Spinal neostigmine diminishes, but does not abolish, hypotension from spinal bupivacaine in sheep.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:5

    Topics: Analgesia; Anesthesia, Spinal; Anesthetics, Local; Animals; Blood Pressure; Bupivacaine; Hypotension

1996
[The effect of activation and blockade of the renin-angiotensin system on the hypotensive activity of the cholinergic system].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1992, Volume: 78, Issue:5

    Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Re

1992
Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.
    Anaesthesia, 1987, Volume: 42, Issue:12

    Topics: Aged; Atenolol; Bradycardia; Drug Interactions; Female; Humans; Hypotension; Neostigmine; Pancuroniu

1987
Safe reversal. 1. Atropine followed by neostigmine. An electrocardiographic study.
    British journal of anaesthesia, 1968, Volume: 40, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Arrhythmias, Cardiac; Atropine; Heart; Heart Rate; Humans; Hypotension

1968
Anaesthesia for renal transplantation. A preliminary report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Apr-11, Volume: 44, Issue:15

    Topics: Anesthesia; Anesthesia, Spinal; Blood Pressure Determination; Cadaver; Cyclopropanes; Ethers; Ethyl

1970
Diallylnortoxiferine? Difficult to reverse.
    Anaesthesia, 1970, Volume: 25, Issue:2

    Topics: Atropine; Humans; Hypotension; Muscle Relaxants, Central; Neostigmine

1970