neostigmine has been researched along with Atelectasis in 5 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We concluded that sugammadex is more effective at reducing the incidence of PPCs including pneumonia, atelectasis, NIV and reintubation compared with neostigmine." | 5.41 | Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis. ( Liang, P; Liu, HM; Yu, H; Zuo, YD, 2023) |
| "During general anaesthesia for VATS, compared with cisatracurium and neostigmine, use of rocuronium and sugammadex was associated with a significant decrease in the incidence of postoperative delayed removal of the chest tube, atelectasis, and pulmonary consolidation." | 4.31 | Use of rocuronium and sugammadex for video-assisted thoracoscopic surgery is associated with reduced duration of chest tube drainage: a propensity score-matched analysis. ( Chin, JC; Huang, CJ; Huang, SC; Illias, AM; Lu, HI; Shih, TH; Wang, PM; Wu, EB; Wu, SC, 2023) |
| "Neostigmine reversal did not affect oxygenation but was associated with increased atelectasis." | 3.80 | Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study. ( Doran, ME; Eikermann, M; Hoang, AH; Igumenshcheva, A; MacDonald, T; Malviya, SA; Meyer, MJ; Sasaki, N; Stanislaus, AB, 2014) |
| "Median [interquartile range (IQR)] atelectasis area was 9." | 2.90 | Effects of neuromuscular block reversal with sugammadex versus neostigmine on postoperative respiratory outcomes after major abdominal surgery: a randomized-controlled trial. ( Alday, E; Alvarez, C; Mata, E; Muñoz, M; Planas, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, EB | 1 |
| Huang, SC | 1 |
| Lu, HI | 1 |
| Illias, AM | 1 |
| Wang, PM | 1 |
| Huang, CJ | 1 |
| Shih, TH | 1 |
| Chin, JC | 1 |
| Wu, SC | 1 |
| Liu, HM | 1 |
| Yu, H | 1 |
| Zuo, YD | 1 |
| Liang, P | 1 |
| Bai, YX | 1 |
| Han, JJ | 1 |
| Liu, J | 1 |
| Li, X | 1 |
| Xu, ZZ | 1 |
| Lv, Y | 1 |
| Liu, KX | 1 |
| Wu, QP | 1 |
| Alday, E | 1 |
| Muñoz, M | 1 |
| Planas, A | 1 |
| Mata, E | 1 |
| Alvarez, C | 1 |
| Sasaki, N | 1 |
| Meyer, MJ | 1 |
| Malviya, SA | 1 |
| Stanislaus, AB | 1 |
| MacDonald, T | 1 |
| Doran, ME | 1 |
| Igumenshcheva, A | 1 |
| Hoang, AH | 1 |
| Eikermann, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Electromyographic Activity of the Diaphragm and of the Rectus Abdominis and Intercostal Muscles During Neostigmine, Sugammadex, or Neostigmine-sugammadex Enhanced Recovery After Neuromuscular Blockade With Rocuronium. A Randomised Controlled Study in Heal[NCT02403063] | Phase 4 | 18 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| A Randomized, Blinded-assessor, Single Center Study to Determine if Administration of Sugammadex, When Used to Reverse Deep Neuromuscular Blockade (NMB) After Open Abdominal Surgery, Impacts Hospital Efficiency[NCT02860507] | Phase 4 | 50 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Effects of Postoperative Residual Paralysis on Costs of Hospital Care, Length of Hospitalization and Intensive Care Unit Admission Rate[NCT01718860] | 3,000 participants (Anticipated) | Observational | 2011-04-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02860507)
Timeframe: through discharge from hospital, average of 72 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Neostigmine + Glycopyrrolate | 8 |
| Sugammadex | 10 |
(NCT02860507)
Timeframe: through start of next surgery, average of 2 hours
| Intervention | Minutes (Mean) |
|---|---|
| Neostigmine + Glycopyrrolate | 49.7 |
| Sugammadex | 49.45 |
2 reviews available for neostigmine and Atelectasis
| Article | Year |
|---|---|
Postoperative pulmonary complications after sugammadex reversal of neuromuscular blockade: a systematic review and meta-analysis with trial sequential analysis.
Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular Blocking Agent | 2023 |
Sugammadex Reduced the Incidence of Postoperative Pulmonary Complications in Susceptible Patients Identified by ARISCAT Risk Index: Systematic Review and Meta-analysis.
Topics: Humans; Incidence; Neostigmine; Neuromuscular Blockade; Postoperative Complications; Pulmonary Atele | 2023 |
1 trial available for neostigmine and Atelectasis
| Article | Year |
|---|---|
Effects of neuromuscular block reversal with sugammadex versus neostigmine on postoperative respiratory outcomes after major abdominal surgery: a randomized-controlled trial.
Topics: Abdomen; Aged; Female; Humans; Male; Middle Aged; Neostigmine; Neuromuscular Blockade; Postoperative | 2019 |
2 other studies available for neostigmine and Atelectasis
| Article | Year |
|---|---|
Use of rocuronium and sugammadex for video-assisted thoracoscopic surgery is associated with reduced duration of chest tube drainage: a propensity score-matched analysis.
Topics: Anesthesia, General; Chest Tubes; Cholinesterase Inhibitors; Drainage; Humans; Neostigmine; Neuromus | 2023 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |
Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.
Topics: Adult; Aged; Airway Extubation; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; | 2014 |