Page last updated: 2024-10-31

neostigmine and Ataxia

neostigmine has been researched along with Ataxia in 5 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Neostigmine methylsulfate has a quaternary ammonium group, which prevents its penetration through the blood-brain barrier; hence its primary influence is believed to be due to its action on the peripheral nervous system."5.31A female with central anticholinergic syndrome responsive to neostigmine. ( Francia, A; Parisi, P, 2000)
"All treatments induced mild or moderate ataxia."2.77Efficacy of concurrent epidural administration of neostigmine and lidocaine for perineal analgesia in geldings. ( DeRossi, R; Maciel, FB; Módolo, TJ; Pagliosa, RC, 2012)
"Neostigmine methylsulfate has a quaternary ammonium group, which prevents its penetration through the blood-brain barrier; hence its primary influence is believed to be due to its action on the peripheral nervous system."1.31A female with central anticholinergic syndrome responsive to neostigmine. ( Francia, A; Parisi, P, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeRossi, R1
Maciel, FB1
Módolo, TJ1
Pagliosa, RC1
Shetisky, GM1
Shuster, J1
Dilts, SL1
Parisi, P1
Francia, A1
Duvoisin, RC1
Katz, R1

Trials

1 trial available for neostigmine and Ataxia

ArticleYear
Efficacy of concurrent epidural administration of neostigmine and lidocaine for perineal analgesia in geldings.
    American journal of veterinary research, 2012, Volume: 73, Issue:9

    Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Ataxia; Blood Pressure; Body Temperature; Cholines

2012

Other Studies

4 other studies available for neostigmine and Ataxia

ArticleYear
Ataxia telangiectasia.
    Henry Ford Hospital medical journal, 1967, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Ataxia; Curare; Edrophonium; Female; Humans; Male; Neostigmine

1967
Berry CA: Effect of cholinergic drugs on passive avoidance in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Animals; Ataxia; Atropine; Avoidance Learning; Galvanic Skin Response; Locomotion; Male; Mecamylamin

1967
A female with central anticholinergic syndrome responsive to neostigmine.
    Pediatric neurology, 2000, Volume: 23, Issue:2

    Topics: Ataxia; Blood-Brain Barrier; Child, Preschool; Cholinesterase Inhibitors; Female; Hallucinations; Hu

2000
Reversal of central anticholinergic syndrome in man by physostigmine.
    JAMA, 1968, Nov-25, Volume: 206, Issue:9

    Topics: Aged; Ataxia; Central Nervous System Diseases; Child; Cognition Disorders; Delirium; Female; Halluci

1968