Page last updated: 2024-10-31

neostigmine and Arrhythmias, Cardiac

neostigmine has been researched along with Arrhythmias, Cardiac in 50 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"Cardiac arrhythmias were induced by potassium chloride intravenously as a bolus injection in a dose of 0."5.26Effects of atropine, isoprenaline, neostigmine and practocol on cardiac arrhythmias induced by potassium in anesthetized dogs. ( Alitalo, I; Hietala, A, 1977)
" The only existed anticholinergic in Thailand is atropine, which has a more rapid onset than neostigmine resulting in initial tachycardia."5.19A comparison of the combination of atropine and glycopyrrolate with atropine alone for the reversal of muscle relaxant. ( Ittichaikulthol, W; Komonhirun, R; Piathong, P; Pisitsak, C; Suyawet, R; Wirachpisit, N, 2014)
"The effect of increased cholinergic activity on reperfusion induced ventricular arrhythmias was studied in alpha chloralose anaesthetised dogs by administering neostigmine during a 25 min occlusion of the anterior left descending coronary artery."3.67Role of increased cholinergic activity in reperfusion induced ventricular arrhythmias. ( Abete, P; Bonaduce, D; Canonico, V; Ferrara, N; Leosco, D; Longobardi, G; Rengo, F, 1987)
" It is suggested that the dosage of anticholinergic agents given with neostigmine could be reduced in elderly patients in comparison to that in younger patients."1.27Antagonism of neuromuscular block in the elderly. A comparison of atropine and glycopyrronium in a mixture with neostigmine. ( Mirakhur, RK, 1985)
"Edrophonium (0."1.26Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia. ( Cronnelly, R; Miller, RD; Morris, RB, 1982)
"Cardiac arrhythmias were induced by potassium chloride intravenously as a bolus injection in a dose of 0."1.26Effects of atropine, isoprenaline, neostigmine and practocol on cardiac arrhythmias induced by potassium in anesthetized dogs. ( Alitalo, I; Hietala, A, 1977)
"Supraventricular arrhythmias occurred less frequently in the pyridostigmine groups than in the neostigmine groups."1.26Effects on muscarinic receptors of various agents in reversal of neuro-muscular blockade: a study evaluating atropine, glycopyrron, neostigmine and pyridostigmine. ( Eriksen, S; Hansen, EK; Hasselstrøm, L, 1978)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199045 (90.00)18.7374
1990's2 (4.00)18.2507
2000's2 (4.00)29.6817
2010's1 (2.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ittichaikulthol, W1
Pisitsak, C1
Wirachpisit, N1
Piathong, P1
Suyawet, R1
Komonhirun, R1
Thomas, MC1
Erstad, BL1
HAEGER, K2
JOHANSSON, B2
SJOSTROM, B2
YU, KJ1
HUANG, MH1
CHIANG, SC1
LU, CW1
CHENG, TS1
LAN, HC1
FENG, CJ1
GOTTLIEB, JD1
SWEET, RB1
BELLET, S1
EICHBAUM, FW1
PEREIRA, CB1
GREENWOOD, RJ1
IMMEL, E1
TILLING, W1
CUNNINGHAM, GC1
SCHINITZKER, WF1
Hayashida, H1
Miyauchi, Y1
Vassalle, M1
Caress, DL1
Slovin, AJ1
Stuckey, JH1
Takkunen, O1
Salmenperä, M1
Heinonen, J1
Cronnelly, R1
Morris, RB1
Miller, RD1
Homola, D1
Srnova, V1
Shutt, LE1
Bowes, JB1
Alitalo, I1
Hietala, A1
Eriksen, S1
Hansen, EK1
Hasselstrøm, L1
Muravchick, S1
Owens, WD1
Felts, JA1
Gyermek, L1
Raymond, CW1
Wetterslev, J1
Jarnvig, I1
Jørgensen, LN1
Olsen, NV1
Spiers, SP1
Yungbluth, J1
Henry, JD1
McAnallen, K1
Albee, DT1
Ferrara, N2
Bonaduce, D2
Abete, P2
Leosco, D2
Caccese, P1
Tuccillo, B1
Longobardi, G2
Canonico, V2
Rengo, F2
Mirakhur, RK1
Berry, FA1
Lake, CL1
Johns, RA1
Rogers, BM1
Schamroth, L1
Robinson, SJ1
Lees, P1
Tavernor, WD1
Schoenberg, AA1
Mennicken, U1
Simon, R1
Brambring, P1
Heintzen, PH1
James, TN1
Kanarek, KS1
Thomson, PD1
Levin, SE1
List, WF1
Baraka, A2
Marriott, HJ1
Smith, M1
Ray, CT1
Rossier, AB2
Ziegler, WH2
Duchosal, PW2
Meylan, J2
Rosner, V1
Kepes, ER1
Foldes, FF1
Huidobro, F1
Lewin, J1
Huidobro, JP1
Garbarino, JA1
Samaniego, E1
Ghoneim, MM1
Kjellberg, M1
Tammisto, T1
Salem, MR1
Ylagan, LB1
Angel, JJ1
Vedam, VS1
Collins, VJ1
Gil'mar, IS1
Mei, V1
Sardella, F1
Valora, N1
Fekete, M1
Pevzner, GI1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized Trial of Enteral Naloxone Versus a Traditional Bowel Regimen in Prevention of Constipation and Decreased Gastric Motility in Critically Ill Trauma Patients[NCT00799201]Phase 43 participants (Actual)Interventional2007-08-31Terminated (stopped due to Naloxone became unavailable due to manufacturing shortatges requiring the study to be terminated.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for neostigmine and Arrhythmias, Cardiac

ArticleYear
CHEMICAL THERAPY OF CARDIAC ARRHYTHMIAS.
    Biochemical clinics, 1963, Volume: 2

    Topics: Acetylcholine; Arrhythmias, Cardiac; Atropine; Digitalis; Digitalis Glycosides; Ephedrine; Epinephri

1963
Atropine and hyoscine.
    Anaesthesia, 1979, Volume: 34, Issue:5

    Topics: Arrhythmias, Cardiac; Atropine; Cardiac Output; Central Nervous System; Chemical Phenomena; Chemistr

1979
The diagnosis, significance, and management of A-V nodal rhythms.
    Cardiovascular clinics, 1970, Volume: 2, Issue:2

    Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atropine; Cardia

1970
Treatment of cardiac arrhythmias.
    Pediatric clinics of North America, 1964, Volume: 11, Issue:2

    Topics: Adams-Stokes Syndrome; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter;

1964
[Cardiac arrhythmias during anesthesia: their origin and pharmacological control].
    Der Anaesthesist, 1966, Volume: 15, Issue:11

    Topics: Anesthetics; Arrhythmias, Cardiac; Catecholamines; Digitalis Glycosides; Electroshock; Heart Disease

1966
Management of cardiac dysrhythmias complicating acute myocardial infarction.
    Geriatrics, 1968, Volume: 23, Issue:9

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compound

1968

Trials

4 trials available for neostigmine and Arrhythmias, Cardiac

ArticleYear
A comparison of the combination of atropine and glycopyrrolate with atropine alone for the reversal of muscle relaxant.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:7

    Topics: Adult; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Cholinesterase Inhibitors; Glycopyrrolat

2014
Safety of enteral naloxone and i.v. neostigmine when used to relieve constipation.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jun-15, Volume: 60, Issue:12

    Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Colic;

2003
Split-dose atropine versus glycopyrrolate with neostigmine for reversal of gallamine-induced neuromuscular blockade.
    Acta anaesthesiologica Scandinavica, 1991, Volume: 35, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Atropine; Female; Gallamine Triethiodide; Glycopyrrolate; Heart Rate; H

1991
Recovery characteristics following antagonism of vecuronium with edrophonium, neostigmine or pyridostigmine.
    AANA journal, 1988, Volume: 56, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cholinesterase Inhibitors; Clinical Trials as Top

1988

Other Studies

40 other studies available for neostigmine and Arrhythmias, Cardiac

ArticleYear
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Electrocardiographic studies on fibrillating and nonfibrillating hypothermic dogs with or without previous treatment with acetylcholine or procaine amide.
    American heart journal, 1957, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; D

1957
Arrhythmias and their management during mitral commissurotomy; with special reference to persistent ventricular flutter.
    Chinese medical journal (Peking, China : 1932), 1957, Volume: 75, Issue:7

    Topics: Arrhythmias, Cardiac; Cardiac Surgical Procedures; Digitalis; Digitalis Glycosides; Mitral Valve Ste

1957
The antagonism of curare: the cardiac effects of atropine and neostigmine.
    Canadian Anaesthetists' Society journal, 1963, Volume: 10

    Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Curare; Heart; Humans; Neostigmine

1963
EFFECT OF CRANIAL TRAUMA ON THE ELECTROCARDIOGRAM EXPERIMENTS IN GUINEA-PIGS.
    Cardiologia, 1964, Volume: 44

    Topics: Arrhythmias, Cardiac; Atropine; Brain Injuries; Craniocerebral Trauma; Electrocardiography; Ergotami

1964
THE PROPER USE OF CAROTID SINUS STIMULATION.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Carotid Sinus; Diagnosis; Digitalis Glycosides; Drug Therapy;

1964
[ON THE CLINICAL ASPECTS OF BOTULISM].
    Arztliche Forschung, 1965, Jan-10, Volume: 19

    Topics: Acetylcholine; Arrhythmias, Cardiac; Botulism; Drug Therapy; Eye Manifestations; Humans; Muscular Di

1965
Use of neo-synephrine in paroxysmal supraventricular tachycardia.
    The Journal of pediatrics, 1950, Volume: 37, Issue:5

    Topics: Arrhythmias, Cardiac; Neostigmine; Phenylephrine; Tachycardia, Supraventricular

1950
Anaesthetic management in patients with high-risk Brugada syndrome.
    British journal of anaesthesia, 2006, Volume: 97, Issue:1

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Administration Schedule;

2006
On the cause of ventricular asystole during vagal stimulation.
    Circulation research, 1967, Volume: 20, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Heart; Heart Conduction System; Neostigmi

1967
Atropine vs glycopyrrolate during reversal of pancuronium block in patients anaesthetized with halothane.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:4

    Topics: Adult; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Electrocardiography; Fem

1984
Edrophonium: duration of action and atropine requirement in humans during halothane anesthesia.
    Anesthesiology, 1982, Volume: 57, Issue:4

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Dose-Response Relationship, Dru

1982
Anomalous atrio-ventricular connections and their features.
    Advances in cardiology, 1976, Volume: 16

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventr

1976
Effects of atropine, isoprenaline, neostigmine and practocol on cardiac arrhythmias induced by potassium in anesthetized dogs.
    Nordisk veterinaermedicin, 1977, Volume: 29, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Autonomic Agents; Dogs; Female; Heart Rate; Homeostasis; Is

1977
Effects on muscarinic receptors of various agents in reversal of neuro-muscular blockade: a study evaluating atropine, glycopyrron, neostigmine and pyridostigmine.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Atropine; Glycopyrrolate; Heart Rate; Humans; Middle Aged;

1978
Glycopyrrolate and cardiac dysrhythmias in geriatric patients after reversal of neuromuscular blockade.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Cardiovascular Diseases; Cholinesterase Inhibitors; Glycopyrro

1979
Clinical pharmacology of the reversal of neuromuscular block.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Edrophonium; Femal

1977
Letter: Neostigmine methysulfate in the treatment of cardiac arryhthmia induced by perphenazine-amitriptyline.
    Canadian Medical Association journal, 1976, Jan-24, Volume: 114, Issue:2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Child, Preschool; Drug Combin

1976
Atropine or glycopyrronium?--a dangerous dilemma.
    Anaesthesia, 1991, Volume: 46, Issue:2

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Female; Glycopyrrolate; Humans; Neostigmine; Neuromuscular Jun

1991
[Role of the increased cholinergic activity in prevention of reperfusion-induced arrhythmia in dog experiments].
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Rate; Male; Neostigmine; Parasy

1987
Role of increased cholinergic activity in reperfusion induced ventricular arrhythmias.
    Cardiovascular research, 1987, Volume: 21, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Coronary Circulation; Dogs; Female; Heart Rate; Heart Ventr

1987
Antagonism of neuromuscular block in the elderly. A comparison of atropine and glycopyrronium in a mixture with neostigmine.
    Anaesthesia, 1985, Volume: 40, Issue:3

    Topics: Age Factors; Aged; Arrhythmias, Cardiac; Atropine; Female; Glycopyrrolate; Heart Rate; Humans; Male;

1985
Mitral valve prolapse--another cause of intraoperative dysrhythmias in the pediatric patient.
    Anesthesiology, 1985, Volume: 62, Issue:5

    Topics: Adolescent; Arrhythmias, Cardiac; Atropine; Enflurane; Funnel Chest; Halothane; Humans; Intraoperati

1985
An investigation of the actions of the neuromuscular blocking agent, dipyrandium iodide, on cardiovascular and respiratory function in the horse.
    Research in veterinary science, 1969, Volume: 10, Issue:5

    Topics: Androstanes; Anesthesia, Inhalation; Animals; Apnea; Arrhythmias, Cardiac; Blood Circulation; Blood

1969
Stroke volume estimation from aortic pressure with correction for arrhythmias.
    European journal of cardiology, 1974, Volume: 2, Issue:1

    Topics: Animals; Aorta; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Blood Pressure; Cardiac Output; C

1974
Sicknesses of the sinus node.
    The Western journal of medicine, 1974, Volume: 121, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Atrioventricular Node; Depression, Chemical; Dogs; Exercise Test; Hea

1974
The management of imipramine (Tofranil) intoxication in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-19, Volume: 47, Issue:19

    Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lava

1973
Safe reversal. 1. Atropine followed by neostigmine. An electrocardiographic study.
    British journal of anaesthesia, 1968, Volume: 40, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Arrhythmias, Cardiac; Atropine; Heart; Heart Rate; Humans; Hypotension

1968
Cardiac arrhythmias, increased intracranial pressure, and the autonomic nervous system.
    Chest, 1972, Volume: 61, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Autonomic Nervous System; Blood Pressure; Dogs; Electrocard

1972
Sexual function and dysreflexia.
    Paraplegia, 1971, Volume: 9, Issue:1

    Topics: Accidents, Traffic; Adult; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Dysautonomia, Famil

1971
The effects of atropine and neostigmine on heart rate and rhythm. Recommendation for their use to reverse residual neuromuscular block.
    British journal of anaesthesia, 1971, Volume: 43, Issue:11

    Topics: Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Benperidol; Female; Fentanyl; Halo

1971
[Sexual function, autonomic dysreflexia and catecholamines in traumatic medullary lesions].
    Schweizerische medizinische Wochenschrift, 1971, May-29, Volume: 101, Issue:21

    Topics: Adult; Arrhythmias, Cardiac; Blood Pressure Determination; Catecholamines; Dysautonomia, Familial; E

1971
Quinine-like actions of two 2-amino-2-phenol alkyl derivatives.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Blood Pressure; Butyrates; Carotid Arteries; Cats; Che

1969
[Magnesium-ion physiology].
    Anesthesiology, 1970, Volume: 33, Issue:3

    Topics: Adjuvants, Anesthesia; Arrhythmias, Cardiac; Atropine; Calcium; Humans; Magnesium; Neostigmine

1970
Heart-rate changes after atropine and neostigmine given for the reversion of muscle paralysis.
    Acta anaesthesiologica Scandinavica, 1970, Volume: 14, Issue:3

    Topics: Adult; Arrhythmias, Cardiac; Atropine; Heart Rate; Humans; Middle Aged; Neostigmine; Paralysis; Tubo

1970
Reversal of curarization with atropine-neostigmine mixture in patients with congenital cardiac disease.
    British journal of anaesthesia, 1970, Volume: 42, Issue:11

    Topics: Adolescent; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Cyanosis; Electrocardiography;

1970
Safe reversal. 2. Atropine-neostigmine mixture: an electrocardiographic study.
    British journal of anaesthesia, 1968, Volume: 40, Issue:1

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Arrhythmias, Cardiac; Atropine; Carbon Dioxide; Electrocar

1968
[Controlling attacks of paroxysmal tachycardia and fibrillation arrhythmia].
    Vrachebnoe delo, 1968, Volume: 3

    Topics: Arrhythmias, Cardiac; Glucose; Humans; Neostigmine; Procainamide; Quinine; Strophanthins

1968
[Action some drugs on the electrocardiogram of the rat. XII. Prostigmine].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Mar-31, Volume: 41, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Electrocardiography; Heart; Neostigmine; Rats

1965
A possible role of cholinergic effects in the noradrenaline potentiating action of imipramine.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cats; Dogs; Electrocardiography; Female; Hexamethonium C

1966
[On a rare form of disorder of heart rhythm in proserine therapy].
    Klinicheskaia meditsina, 1966, Volume: 44, Issue:8

    Topics: Adult; Arrhythmias, Cardiac; Female; Humans; Neostigmine

1966