neostigmine has been researched along with Allodynia in 7 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sprague-Dawley rats were used to test the analgesic effect of pentazocine and neostigmine using the paw formalin pain model and the incision mechanical allodynia model." | 8.12 | Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats. ( Bai, X; Guo, J; Huang, H; Ouyang, H; Wu, S; Zhang, K, 2022) |
| "Sprague-Dawley rats were used to test the analgesic effect of pentazocine and neostigmine using the paw formalin pain model and the incision mechanical allodynia model." | 4.12 | Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats. ( Bai, X; Guo, J; Huang, H; Ouyang, H; Wu, S; Zhang, K, 2022) |
| " Two hours later (T1), both hindpaws were tested for inflammation (paw circumference) and for hyperalgesia (paw withdrawal threshold) and subsequently 20 microg of neostigmine was injected in the right hind paw." | 3.71 | Lack of peripheral analgesia mediated by intraplantar administration of neostigmine in carrageenan-injected rats. ( Benhamou, D; Bouaziz, H; Fletcher, D; Gentili, ME; Girard, F; Laxenaire, MC; Mazoit, JX, 2001) |
| "On the other hand, in the presence of neuropathic pain, atropine (300 μg) did not alter the nociceptive threshold induced by constriction of the sciatic nerve." | 1.37 | Peripheral control of inflammatory but not neuropathic pain by endogenous cholinergic system. ( Alves, DP; Duarte, ID; Motta, PG; Perez, AC, 2011) |
| "Pretreatment with atropine (0." | 1.33 | Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury. ( Honda, M; Ono, H; Takasu, K; Tanabe, M, 2006) |
| "0 microg) were administered to obtain the dose-response curve and the 50% effective dose (ED(50))." | 1.31 | The interaction between intrathecal neostigmine and GABA receptor agonists in rats with nerve ligation Injury. ( Choi, IC; Han, SM; Hwang, JH; Hwang, KS; Kim, JU; Park, PH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, H | 1 |
| Bai, X | 1 |
| Zhang, K | 1 |
| Guo, J | 1 |
| Wu, S | 1 |
| Ouyang, H | 1 |
| Kanashiro, A | 1 |
| Talbot, J | 1 |
| Peres, RS | 1 |
| Pinto, LG | 1 |
| Bassi, GS | 1 |
| Cunha, TM | 1 |
| Cunha, FQ | 1 |
| Motta, PG | 1 |
| Perez, AC | 1 |
| Alves, DP | 1 |
| Duarte, ID | 1 |
| Patil, CS | 1 |
| Jain, NK | 1 |
| Singh, VP | 1 |
| Kulkarni, SK | 1 |
| Takasu, K | 1 |
| Honda, M | 1 |
| Ono, H | 1 |
| Tanabe, M | 1 |
| Bouaziz, H | 1 |
| Gentili, ME | 1 |
| Girard, F | 1 |
| Mazoit, JX | 1 |
| Benhamou, D | 1 |
| Laxenaire, MC | 1 |
| Fletcher, D | 1 |
| Hwang, JH | 1 |
| Hwang, KS | 1 |
| Kim, JU | 1 |
| Choi, IC | 1 |
| Park, PH | 1 |
| Han, SM | 1 |
7 other studies available for neostigmine and Allodynia
| Article | Year |
|---|---|
Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats.
Topics: Analgesics; Animals; Atropine Derivatives; Clonidine; Formaldehyde; Humans; Hyperalgesia; Naloxone; | 2022 |
Neutrophil Recruitment and Articular Hyperalgesia in Antigen-Induced Arthritis are Modulated by the Cholinergic Anti-Inflammatory Pathway.
Topics: Animals; Antigens; Arthritis, Experimental; Arthritis, Rheumatoid; Atropine Derivatives; Cholinergic | 2016 |
Peripheral control of inflammatory but not neuropathic pain by endogenous cholinergic system.
Topics: Animals; Atropine; Carrageenan; Cholinergic Agents; Cholinesterase Inhibitors; Dinoprostone; Disease | 2011 |
Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Acetylcholine; Animals; Carrageenan; Cholinergic A | 2004 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyc | 2006 |
Lack of peripheral analgesia mediated by intraplantar administration of neostigmine in carrageenan-injected rats.
Topics: Analgesics; Animals; Carrageenan; Cholinesterase Inhibitors; Foot; Hyperalgesia; Inflammation; Injec | 2001 |
The interaction between intrathecal neostigmine and GABA receptor agonists in rats with nerve ligation Injury.
Topics: Animals; Baclofen; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; G | 2001 |