neostigmine has been researched along with Airway Obstruction in 4 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3% w/v (weight of solute per volume of solution) monoethanolamine (MEA) into his lungs, causing asthma-like symptoms." | 3.75 | Effects of inhaled monoethanolamine on bronchoconstriction. ( Hayashi, I; Ide, A; Kamijo, Y; Majima, M; Soma, K; Yoshimura, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuchs-Buder, T | 1 |
| Nemes, R | 1 |
| Schmartz, D | 1 |
| Kamijo, Y | 1 |
| Hayashi, I | 1 |
| Ide, A | 1 |
| Yoshimura, K | 1 |
| Soma, K | 1 |
| Majima, M | 1 |
| D'Honneur, G | 1 |
| Lofaso, F | 1 |
| Drummond, GB | 1 |
| Rimaniol, JM | 1 |
| Aubineau, JV | 1 |
| Harf, A | 1 |
| Duvaldestin, P | 1 |
| Overton, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Sugammadex (2mg/kg) to Shorten Time-to-extubation Among Postoperative ICU Patients Following AVR, CABG Surgery, or AVR/CABG Surgery- a Prospective Randomized Placebo-controlled Trial.[NCT03196167] | Phase 4 | 90 participants (Actual) | Interventional | 2017-05-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in renal function was defined as Creatinine elevation >0.5 mg/dl (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Sugammadex Group | 5 |
| Placebo Group | 3 |
Length of Hospital stay after surgery (NCT03196167)
Timeframe: 2 weeks
| Intervention | Days (Median) |
|---|---|
| Sugammadex Group | 5 |
| Placebo Group | 5 |
Days in the ICU post opertaitvely (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | days (Median) |
|---|---|
| Sugammadex Group | 2 |
| Placebo Group | 2 |
NIF=Negative Inspiratory Force (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | cm per H2O (Median) |
|---|---|
| Sugammadex Group | -33.0 |
| Placebo Group | -31.0 |
Any dysrhythmia after surgery in patients without history of dysrhythmia (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Sugammadex Group | 3 |
| Placebo Group | 6 |
Postoperative congestive heart failure (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Sugammadex Group | 0 |
| Placebo Group | 1 |
Rapid Shallow Breathing Index (NCT03196167)
Timeframe: Upto 2 weeks
| Intervention | breaths/min/L (Median) |
|---|---|
| Sugammadex Group | 40.0 |
| Placebo Group | 32.7 |
The primary outcome of this study aims to test the time to extubation among patients in the cardiothoracic ICU who have undergone isolated CABG. (NCT03196167)
Timeframe: Up to 2 weeks
| Intervention | minutes (Median) |
|---|---|
| Sugammadex | 126.0 |
| Placebo | 219.0 |
1 review available for neostigmine and Airway Obstruction
| Article | Year |
|---|---|
Residual neuromuscular blockade: management and impact on postoperative pulmonary outcome.
Topics: Airway Obstruction; Anesthesia Recovery Period; Cholinesterase Inhibitors; Delayed Emergence from An | 2016 |
1 trial available for neostigmine and Airway Obstruction
| Article | Year |
|---|---|
Susceptibility to upper airway obstruction during partial neuromuscular block.
Topics: Adult; Airway Obstruction; Airway Resistance; Cholinesterase Inhibitors; Disease Susceptibility; Hum | 1998 |
2 other studies available for neostigmine and Airway Obstruction
| Article | Year |
|---|---|
Effects of inhaled monoethanolamine on bronchoconstriction.
Topics: Aerosols; Air Pollutants, Occupational; Airway Obstruction; Airway Resistance; Animals; Asthma; Atro | 2009 |
Common problems in paediatric anaesthesia.
Topics: Airway Obstruction; Anesthesia, General; Atropine; Blood Transfusion; Body Temperature; Child; Human | 1976 |