neoarsphenamine has been researched along with Dermatitis--Contact* in 1 studies
1 other study(ies) available for neoarsphenamine and Dermatitis--Contact
Article | Year |
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IMMUNOLOGICAL TOLERANCE INDUCED IN ANIMALS PREVIOUSLY SENSITIZED TO SIMPLE CHEMICAL COMPOUNDS.
Adult guinea pigs develop a delayed hypersensitivity to intradermally injected neoarsphenamine. If the animals are treated intravenously with high doses of this compound before sensitization, a specific and permanent immunological tolerance develops. Permanent tolerance is also obtained in previously sensitized animals when an intravenous injection of neoarsphenamine isfollowed 6 hours later by an intradermal one. When, however, the interval between the two injections is extended to 7 or 14 days, no tolerance is observed. Topics: Animals; Antigen-Antibody Reactions; Arsphenamine; Dermatitis; Dermatitis, Contact; Drug Tolerance; Guinea Pigs; Hypersensitivity, Delayed; Immune Tolerance; Research; Toxicology | 1964 |